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The map label for this gene is fbaA

Identifier: 57238207

GI number: 57238207

Start: 630395

End: 631459

Strand: Direct

Name: fbaA

Synonym: CJE0700

Alternate gene names: 57238207

Gene position: 630395-631459 (Clockwise)

Preceding gene: 57238208

Following gene: 57238206

Centisome position: 35.46

GC content: 35.02

Gene sequence:

>1065_bases
ATGGGTGTTTTAGACATTGTAAAAGCAGGGGTGATTAGCGGAGATGAGCTTAATAAAATTTATGACTATGCTAAAGCAGA
GGGTTTTGCTATCCCTGCTGTTAATGTTGTAGGAACTGATTCTATTAATGCAGTTTTAGAAGCTGCAAAAAAAGTTAACT
CTCCAGTTATTATCCAGTTTTCAAATGGTGGGGCAAAATTTTATGCAGGGAAAAATTGTCCTAATGGAGAAGTTTTAGGT
GCAATTAGTGGGGCTAAACATGTACATTTACTTGCTAAAGCTTATGGTGTACCTGTGATTTTACACACTGATCATGCTGC
AAGAAAACTTTTGCCTTGGATTGATGGGCTTATTGAGGCAAATGCACAATATAAAAAAACCCATGGACAAGCTTTATTTA
GTTCTCATATGCTTGATCTTAGCGAAGAAAGTTTAGAAGAAAATCTTAGCACTTGTGAAGTTTATCTTCAAAAACTTGAT
GCTTTAGGTGTCGCGCTTGAAATAGAATTAGGTTGTACAGGTGGCGAAGAAGATGGAGTGGATAATACAGGTATTGATAA
TTCCAAGCTTTATACCCAACCAGAAGATGTAGCTCTTGCATATGAAAGACTTGGAAAAATTAGTGATAAATTTTCAATCG
CAGCAAGCTTTGGAAATGTACATGGAGTTTACAAGCCAGGAAATGTTAGCTTACAACCTGAAATTTTAAAAAATTCGCAA
AAATTTGTAAAAGATAAATTTGCTTTAAATAGCGATAAGCCTATAAATTTTGTATTTCATGGCGGTAGCGGTAGTGAGCT
AAAAGATATTAAAAATGCAGTAAGCTATGGCGTAATTAAGATGAATATTGACACAGATACTCAATGGGCTTTTTGGGATG
GGGTGCGTGAATATGAACTTAAAAATAGGGCTTATTTGCAAGGACAAATTGGAAATCCAGAAGGTGATGACAAGCCAAAT
AAAAAATACTATGATCCGCGTGTTTGGTTAAGAAGCGGTGAAGAAAGCATGATAAAACGTCTTGAAATCGCTTTTGAAGA
TTTAAACTGTATAAACAAAAACTAA

Upstream 100 bases:

>100_bases
AACAAGGTATTGAAAACGGACTTAAATTTGAAGAATTTAAAAAAGTTATCAATCAAAAAGGCCAAGATCTCTTAAATAGT
GCTAAAGTGGAATATAAATA

Downstream 100 bases:

>100_bases
GCATTTTAAAAGCTTAGTTTTATTTTGTTTTAAAAATTTTTATCAAATTAAGTAGCAATCTTTAAAATAAAATTTTTAAT
GAGGTATTGGTTTCATGGAT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MGVLDIVKAGVISGDELNKIYDYAKAEGFAIPAVNVVGTDSINAVLEAAKKVNSPVIIQFSNGGAKFYAGKNCPNGEVLG
AISGAKHVHLLAKAYGVPVILHTDHAARKLLPWIDGLIEANAQYKKTHGQALFSSHMLDLSEESLEENLSTCEVYLQKLD
ALGVALEIELGCTGGEEDGVDNTGIDNSKLYTQPEDVALAYERLGKISDKFSIAASFGNVHGVYKPGNVSLQPEILKNSQ
KFVKDKFALNSDKPINFVFHGGSGSELKDIKNAVSYGVIKMNIDTDTQWAFWDGVREYELKNRAYLQGQIGNPEGDDKPN
KKYYDPRVWLRSGEESMIKRLEIAFEDLNCINKN

Sequences:

>Translated_354_residues
MGVLDIVKAGVISGDELNKIYDYAKAEGFAIPAVNVVGTDSINAVLEAAKKVNSPVIIQFSNGGAKFYAGKNCPNGEVLG
AISGAKHVHLLAKAYGVPVILHTDHAARKLLPWIDGLIEANAQYKKTHGQALFSSHMLDLSEESLEENLSTCEVYLQKLD
ALGVALEIELGCTGGEEDGVDNTGIDNSKLYTQPEDVALAYERLGKISDKFSIAASFGNVHGVYKPGNVSLQPEILKNSQ
KFVKDKFALNSDKPINFVFHGGSGSELKDIKNAVSYGVIKMNIDTDTQWAFWDGVREYELKNRAYLQGQIGNPEGDDKPN
KKYYDPRVWLRSGEESMIKRLEIAFEDLNCINKN
>Mature_353_residues
GVLDIVKAGVISGDELNKIYDYAKAEGFAIPAVNVVGTDSINAVLEAAKKVNSPVIIQFSNGGAKFYAGKNCPNGEVLGA
ISGAKHVHLLAKAYGVPVILHTDHAARKLLPWIDGLIEANAQYKKTHGQALFSSHMLDLSEESLEENLSTCEVYLQKLDA
LGVALEIELGCTGGEEDGVDNTGIDNSKLYTQPEDVALAYERLGKISDKFSIAASFGNVHGVYKPGNVSLQPEILKNSQK
FVKDKFALNSDKPINFVFHGGSGSELKDIKNAVSYGVIKMNIDTDTQWAFWDGVREYELKNRAYLQGQIGNPEGDDKPNK
KYYDPRVWLRSGEESMIKRLEIAFEDLNCINKN

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family

Homologues:

Organism=Escherichia coli, GI1789293, Length=355, Percent_Identity=64.5070422535211, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI87082041, Length=332, Percent_Identity=24.6987951807229, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789526, Length=314, Percent_Identity=25.4777070063694, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788072, Length=288, Percent_Identity=30.2083333333333, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322790, Length=358, Percent_Identity=48.3240223463687, Blast_Score=367, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALF_CAMJE (Q0PAS0)

Other databases:

- EMBL:   AL111168
- PIR:   S52413
- RefSeq:   YP_002344027.1
- ProteinModelPortal:   Q0PAS0
- SMR:   Q0PAS0
- IntAct:   Q0PAS0
- GeneID:   904922
- GenomeReviews:   AL111168_GR
- KEGG:   cje:Cj0597
- HOGENOM:   HBG327581
- OMA:   LNCIDRN
- PhylomeDB:   Q0PAS0
- ProtClustDB:   PRK09197
- BioCyc:   CJEJ192222:CJ0597-MONOMER
- BRENDA:   4.1.2.13
- GO:   GO:0006096
- InterPro:   IPR013785
- InterPro:   IPR006411
- InterPro:   IPR000771
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF001359
- TIGRFAMs:   TIGR00167
- TIGRFAMs:   TIGR01520

Pfam domain/function: PF01116 F_bP_aldolase

EC number: =4.1.2.13

Molecular weight: Translated: 38730; Mature: 38599

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00602 ALDOLASE_CLASS_II_1; PS00806 ALDOLASE_CLASS_II_2

Important sites: ACT_SITE 104-104 BINDING 61-61 BINDING 222-222

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLDIVKAGVISGDELNKIYDYAKAEGFAIPAVNVVGTDSINAVLEAAKKVNSPVIIQF
CCHHHHHHHCCCCCHHHHHHHHHHHCCCEECCEEEEECCCHHHHHHHHHHHCCCCEEEEE
SNGGAKFYAGKNCPNGEVLGAISGAKHVHLLAKAYGVPVILHTDHAARKLLPWIDGLIEA
CCCCEEEEECCCCCCCCEEEECCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHC
NAQYKKTHGQALFSSHMLDLSEESLEENLSTCEVYLQKLDALGVALEIELGCTGGEEDGV
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
DNTGIDNSKLYTQPEDVALAYERLGKISDKFSIAASFGNVHGVYKPGNVSLQPEILKNSQ
CCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHCHH
KFVKDKFALNSDKPINFVFHGGSGSELKDIKNAVSYGVIKMNIDTDTQWAFWDGVREYEL
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHCCCHHHHH
KNRAYLQGQIGNPEGDDKPNKKYYDPRVWLRSGEESMIKRLEIAFEDLNCINKN
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GVLDIVKAGVISGDELNKIYDYAKAEGFAIPAVNVVGTDSINAVLEAAKKVNSPVIIQF
CHHHHHHHCCCCCHHHHHHHHHHHCCCEECCEEEEECCCHHHHHHHHHHHCCCCEEEEE
SNGGAKFYAGKNCPNGEVLGAISGAKHVHLLAKAYGVPVILHTDHAARKLLPWIDGLIEA
CCCCEEEEECCCCCCCCEEEECCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHC
NAQYKKTHGQALFSSHMLDLSEESLEENLSTCEVYLQKLDALGVALEIELGCTGGEEDGV
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
DNTGIDNSKLYTQPEDVALAYERLGKISDKFSIAASFGNVHGVYKPGNVSLQPEILKNSQ
CCCCCCCCEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHCHH
KFVKDKFALNSDKPINFVFHGGSGSELKDIKNAVSYGVIKMNIDTDTQWAFWDGVREYEL
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHCCCHHHHH
KNRAYLQGQIGNPEGDDKPNKKYYDPRVWLRSGEESMIKRLEIAFEDLNCINKN
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204