| Definition | Campylobacter jejuni RM1221, complete genome. |
|---|---|
| Accession | NC_003912 |
| Length | 1,777,831 |
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The map label for this gene is metE [H]
Identifier: 57238073
GI number: 57238073
Start: 1250806
End: 1253070
Strand: Direct
Name: metE [H]
Synonym: CJE1335
Alternate gene names: 57238073
Gene position: 1250806-1253070 (Clockwise)
Preceding gene: 57238072
Following gene: 57238074
Centisome position: 70.36
GC content: 32.19
Gene sequence:
>2265_bases ATGAAAAATTCAATCATTTCTTACCCAAGAATAGGTGCAAATAGAGAATTAAAATTTGCTATTGAAAAATACTTTAAAAA CCAAAGTTCTAAAGAGGAGCTTTTAAAGAGTGCTAAGGATTTAAGGATTAGACACTGGCAAGAAATTCAAAAAGCTGGCA TTGATTTTATCCCTAGTAATGATTTTTCACTTTATGATAATGTCTTAGATGCAGCTGTGCTTTTTAACATTGTTCATACA AAGTATAAAAATTTAAATTTAGATGCTTTAGATGAATACTTTGCTCAAAGTCGAGGTTATCAAGGAGAAAATGGAGATGT TACAGCCTTAGCAATGAAAAAATGGTTCAATACAAATTATCATTATTTGGTGCCTGAGTGCGATAATGCTGATATTATAG CTTTAACAGGGGATAAAATTTTTAAAGAATATCTCGAAGCTAAAGAGCTTGGCATAGAAAGCAAGCCTGTTTTAATAGGC ATTTTCACACTTTTTAAGCTCATTGCCTTTAAAGATGAAAAAACTCAAAAACTCGCCAAAGAAAAGCTTTTAAACGCTTA CATAGAGCTTTTTGATAAACTAAATGAACTTAAAGTGACATGGCTTGAACTTGATGAGCCTTATTTGGTTTATGATTTAA GCAAGGAAGATATCGCTTTGTTTGAAGAATTTTACCAAGAACTTTTAAATCACAAAAAAGATCTTAAAATTTTACTTCAA AGCTATTTTGGAGACTTAAGAGATATTTATCCTAAACTTTTAGAAAGCAAATTTGATGCTTTGGGTCTTGATTTTATCGA AGGTAAACAAAGCTTAGCCTTAGTTCAAAAATACGGCTTTGCTAAAGATAAAATCCTTTTTGCAGGTCTTATTAATGGCA AAAATATCTATACTAATGATTATGCTAAAAGCCTAAAGCTTATTAAAGAGCTTCAAAAATATACACAAAATATCATCTTA AACACTTCTTGCTCACTTTTACATGTGCCTTATAGCACTGAATTTGAAAGCAAATTAGATTCAAACTATCTTAAACTTTT TTCCTTTGCCAAAGAAAAACTTCAAGAACTTAAAGATTTAAAAGAAATTCTAAATTCTAGCGAAGAAAATCCGCTCTTTA GAGCCAATCAAGAGCTTTTTAAAAATATCCCAGAGCGTTTAGATGAAAAAGTCAAAGCAAGGCTTAAGGCTTTAAAAAAA GAAGATTTTACCAGAACGCCTAGTTTTAAAGAACGCGCCTTAATCCAAAAAGAATTTTTAAAACTCCCTCTTTTACCAAC CACAACCATAGGTTCGTTTCCTCAAAGTGCTGATGTAAGATCTAATCGCCTTGCCTTTAAGCAAGAAAAAATTTCAGCTC AAAACTACACTGAATTTAACCAACAAAAAATCAAAGAATGCATACAAATTCAAGAAGAAATAGGACTTGATGTTTTAGTG CATGGAGAATTTGAAAGAAATGATATGGTGGAGTATTTTGGAGAGAATTTAAAGGGCTTTTTATTTACTCAAAATGGCTG GGTTCAAAGCTATGGCACAAGGTGCGTTAAGCCTCCTGTAATTTGGGGTGATGTATCACGCACAAAGCCTATTACCTTAG CTTGGTCTAAATTTGCACAAAGTTTAAGTCAAAAAATCGTAAAAGGTATGCTAACTGGACCTGTAACCATACTTAATTGG TCCTTTCCAAGAGAAGACATCAGTCTAAAAGAAAGCACTGAGCAAATTGCCTTAGCTATAAGAGATGAAGTATTAGATCT TGAAAATGCAGGTATAAAAATCATACAAATTGATGAAGCGGCTTTGCGTGAAAAACTACCTTTAAGAAAAAGTGATTGGC ATAGTGAGTATTTAGATTGGGCTATTCCTGCTTTTAATCTTGTGCATAGCGGGGTAAAAGCTAAAACTCAAATTCACACT CATATGTGTTATAGTGAATTTAGTGATATCTTAAAAGAAATTGACGCTATGGATGCTGATGTGATTTCTTTTGAAGCTTC AAGATCAAACTTAAGTCTTTTAGATACCCTAAAAGCTATTCGTTTTAAAACTGAGGTGGGACCAGGAGTTTATGATATAC ATAGCCCTAGAGTTCCAAGCGTAGAAGAATTAAGTTTAACTATAGAAAAAATTTTAAACAAATTACCTAAGGAGCAAATT TGGATCAATCCAGACTGCGGACTTAAAACAAGAGCCTATGAAGAAGTTATAGCCTCTCTTAAAAATTTAGTTACGGCTAC GCAAAAAATACGAGAACAATTATAA
Upstream 100 bases:
>100_bases TCAAAGCCCTAGTAAAGGCCTTGCAAAGCGATGAAGTTAAAAAATTTATAGAAGAAAAATATCAGGGTGCTTTAATCCCT ACATTTTAAGGAGAACAAAT
Downstream 100 bases:
>100_bases GGAGTTTTCATGTGTAGTTTTTCTTTTGAAGTTTTTCCACCAAGAAAGGATGAAAATATCAAAAATCTTCATGCTATCTT AGATGATTTAGGGCAATTAA
Product: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase
Products: NA
Alternate protein names: Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme [H]
Number of amino acids: Translated: 754; Mature: 754
Protein sequence:
>754_residues MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSNDFSLYDNVLDAAVLFNIVHT KYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNYHYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIG IFTLFKLIAFKDEKTQKLAKEKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQ SYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALVQKYGFAKDKILFAGLINGKNIYTNDYAKSLKLIKELQKYTQNIIL NTSCSLLHVPYSTEFESKLDSNYLKLFSFAKEKLQELKDLKEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKK EDFTRTPSFKERALIQKEFLKLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLV HGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQSLSQKIVKGMLTGPVTILNW SFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEAALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHT HMCYSEFSDILKEIDAMDADVISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQI WINPDCGLKTRAYEEVIASLKNLVTATQKIREQL
Sequences:
>Translated_754_residues MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSNDFSLYDNVLDAAVLFNIVHT KYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNYHYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIG IFTLFKLIAFKDEKTQKLAKEKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQ SYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALVQKYGFAKDKILFAGLINGKNIYTNDYAKSLKLIKELQKYTQNIIL NTSCSLLHVPYSTEFESKLDSNYLKLFSFAKEKLQELKDLKEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKK EDFTRTPSFKERALIQKEFLKLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLV HGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQSLSQKIVKGMLTGPVTILNW SFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEAALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHT HMCYSEFSDILKEIDAMDADVISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQI WINPDCGLKTRAYEEVIASLKNLVTATQKIREQL >Mature_754_residues MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSNDFSLYDNVLDAAVLFNIVHT KYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNYHYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIG IFTLFKLIAFKDEKTQKLAKEKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQ SYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALVQKYGFAKDKILFAGLINGKNIYTNDYAKSLKLIKELQKYTQNIIL NTSCSLLHVPYSTEFESKLDSNYLKLFSFAKEKLQELKDLKEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKK EDFTRTPSFKERALIQKEFLKLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLV HGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQSLSQKIVKGMLTGPVTILNW SFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEAALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHT HMCYSEFSDILKEIDAMDADVISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQI WINPDCGLKTRAYEEVIASLKNLVTATQKIREQL
Specific function: Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation [H]
COG id: COG0620
COG function: function code E; Methionine synthase II (cobalamin-independent)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the vitamin-B12 independent methionine synthase family [H]
Homologues:
Organism=Escherichia coli, GI2367304, Length=753, Percent_Identity=44.7543160690571, Blast_Score=655, Evalue=0.0, Organism=Saccharomyces cerevisiae, GI6320936, Length=771, Percent_Identity=43.1906614785992, Blast_Score=604, Evalue=1e-173,
Paralogues:
None
Copy number: 45,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013215 - InterPro: IPR006276 - InterPro: IPR002629 [H]
Pfam domain/function: PF08267 Meth_synt_1; PF01717 Meth_synt_2 [H]
EC number: =2.1.1.14 [H]
Molecular weight: Translated: 86981; Mature: 86981
Theoretical pI: Translated: 6.47; Mature: 6.47
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSN CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC DFSLYDNVLDAAVLFNIVHTKYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNY CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEHEEHHHHHCCCC HYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIGIFTLFKLIAFKDEKTQKLAK EEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH EKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQ HHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH SYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALVQKYGFAKDKILFAGLINGKNIYTND HHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCEEECHH YAKSLKLIKELQKYTQNIILNTSCSLLHVPYSTEFESKLDSNYLKLFSFAKEKLQELKDL HHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH KEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKKEDFTRTPSFKERALIQKEFL HHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH KLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLV HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEE HGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQ ECCCCCHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCEEECCCCCCCCEEHHHHHHHH SLSQKIVKGMLTGPVTILNWSFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEA HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHH ALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHTHMCYSEFSDILKEIDAMDAD HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH VISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQI HEEEECCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHE WINPDCGLKTRAYEEVIASLKNLVTATQKIREQL EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSN CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC DFSLYDNVLDAAVLFNIVHTKYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNY CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEHEEHHHHHCCCC HYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIGIFTLFKLIAFKDEKTQKLAK EEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH EKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQ HHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH SYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALVQKYGFAKDKILFAGLINGKNIYTND HHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHCCCCCCEEEEEEECCCEEECHH YAKSLKLIKELQKYTQNIILNTSCSLLHVPYSTEFESKLDSNYLKLFSFAKEKLQELKDL HHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH KEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKKEDFTRTPSFKERALIQKEFL HHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH KLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLV HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEE HGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQ ECCCCCHHHHHHHCCCCCEEEEECCCCHHHCCCCCCCCCEEECCCCCCCCEEHHHHHHHH SLSQKIVKGMLTGPVTILNWSFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEA HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHH ALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHTHMCYSEFSDILKEIDAMDAD HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH VISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQI HEEEECCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHE WINPDCGLKTRAYEEVIASLKNLVTATQKIREQL EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA