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The map label for this gene is ompR [H]

Identifier: 57237719

GI number: 57237719

Start: 907672

End: 908334

Strand: Reverse

Name: ompR [H]

Synonym: CJE0969

Alternate gene names: 57237719

Gene position: 908334-907672 (Counterclockwise)

Preceding gene: 57237720

Following gene: 57237718

Centisome position: 51.09

GC content: 27.75

Gene sequence:

>663_bases
ATGTTGAAATTTAAAATTTTAATTATAGAAGATGATATAGATTTAAACGAACTGCTTGTTTTAAAGTTAAAATCTAGTGG
TTATGAAGTTATATCTTTAGCGGATTTTTTTGGAGTTGAAGATTTGCTCGATAATGAGCAAATTGATCTTTTAATAGTCG
ATAGAAATTTGCCCAGTGGAGATTCTTTAGAAAAAATTCAAGATTTAAGAGAGCAAGGATATAAAGAAGCAGTTATTTTT
CTTACAGCCAAGGCTTTACATCAAGATTTGCTCGAAGGCTTTGAAAGTGGTTGTGATGATTATGTTTGTAAACCTTTTGA
TTTCAATGAGCTTTTGCTTCGCATTAAAGCAATTTTAAAACGCCATAAAAAAGAAGAAGAAAAACTATCTTTTGGTGATT
TTATTTTAGATTTGGTTAGTTATGAATTCTTTTACAAAAATCAAAAATTAGAAATCTCAAATCTTGACTATGAGCTTTTA
AAATGTTTTTTTGAAAATCCAAATACCTTGCTTACTAGACAATTTTTAAGCGAAAGTGTTTGGAAGGATGATACTACAAG
TGATAAAACAATCAATATAGCTCTAACAAGACTTAGAAATAAATTTCCAAAACTAAAAGATCATATTATAAGTGTTAGGG
GTATTGGCTATAAATTATGCTAA

Upstream 100 bases:

>100_bases
GGTTTTGGGTATGCTTTGGCTGTTGTTTTGATTGATGAAAAAGTTCAAAAAGAAGTATTAGATGAACTAAAACAATTAGA
GGCGTGTGTATTTGTCCAAT

Downstream 100 bases:

>100_bases
AAACTAAAAATATTTTTATAGTTTTTTTTGTTGTATTGGCTTTGATTTTTGGGTTTATTTTTTATACTTTTACTAATTCT
TATCTTAATTTCTTGCTTAT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MLKFKILIIEDDIDLNELLVLKLKSSGYEVISLADFFGVEDLLDNEQIDLLIVDRNLPSGDSLEKIQDLREQGYKEAVIF
LTAKALHQDLLEGFESGCDDYVCKPFDFNELLLRIKAILKRHKKEEEKLSFGDFILDLVSYEFFYKNQKLEISNLDYELL
KCFFENPNTLLTRQFLSESVWKDDTTSDKTINIALTRLRNKFPKLKDHIISVRGIGYKLC

Sequences:

>Translated_220_residues
MLKFKILIIEDDIDLNELLVLKLKSSGYEVISLADFFGVEDLLDNEQIDLLIVDRNLPSGDSLEKIQDLREQGYKEAVIF
LTAKALHQDLLEGFESGCDDYVCKPFDFNELLLRIKAILKRHKKEEEKLSFGDFILDLVSYEFFYKNQKLEISNLDYELL
KCFFENPNTLLTRQFLSESVWKDDTTSDKTINIALTRLRNKFPKLKDHIISVRGIGYKLC
>Mature_220_residues
MLKFKILIIEDDIDLNELLVLKLKSSGYEVISLADFFGVEDLLDNEQIDLLIVDRNLPSGDSLEKIQDLREQGYKEAVIF
LTAKALHQDLLEGFESGCDDYVCKPFDFNELLLRIKAILKRHKKEEEKLSFGDFILDLVSYEFFYKNQKLEISNLDYELL
KCFFENPNTLLTRQFLSESVWKDDTTSDKTINIALTRLRNKFPKLKDHIISVRGIGYKLC

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=31.4159292035398, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=29.1479820627803, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=31.0502283105023, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=32, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=30, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=28.7671232876712, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=29.2035398230088, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=29.2035398230088, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=26.6375545851528, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=28.5067873303167, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=26.8181818181818, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25643; Mature: 25643

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFKILIIEDDIDLNELLVLKLKSSGYEVISLADFFGVEDLLDNEQIDLLIVDRNLPSG
CEEEEEEEEECCCCCCCEEEEEECCCCCEEEEHHHHHCHHHHHCCCCEEEEEEECCCCCC
DSLEKIQDLREQGYKEAVIFLTAKALHQDLLEGFESGCDDYVCKPFDFNELLLRIKAILK
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
RHKKEEEKLSFGDFILDLVSYEFFYKNQKLEISNLDYELLKCFFENPNTLLTRQFLSESV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
WKDDTTSDKTINIALTRLRNKFPKLKDHIISVRGIGYKLC
CCCCCCCCCEEHHHHHHHHHHCCHHHHHEEHHCCCCEECC
>Mature Secondary Structure
MLKFKILIIEDDIDLNELLVLKLKSSGYEVISLADFFGVEDLLDNEQIDLLIVDRNLPSG
CEEEEEEEEECCCCCCCEEEEEECCCCCEEEEHHHHHCHHHHHCCCCEEEEEEECCCCCC
DSLEKIQDLREQGYKEAVIFLTAKALHQDLLEGFESGCDDYVCKPFDFNELLLRIKAILK
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
RHKKEEEKLSFGDFILDLVSYEFFYKNQKLEISNLDYELLKCFFENPNTLLTRQFLSESV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
WKDDTTSDKTINIALTRLRNKFPKLKDHIISVRGIGYKLC
CCCCCCCCCEEHHHHHHHHHHCCHHHHHEEHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]