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The map label for this gene is phoR [H]

Identifier: 57237718

GI number: 57237718

Start: 906389

End: 907678

Strand: Reverse

Name: phoR [H]

Synonym: CJE0968

Alternate gene names: 57237718

Gene position: 907678-906389 (Counterclockwise)

Preceding gene: 57237719

Following gene: 57237717

Centisome position: 51.06

GC content: 24.96

Gene sequence:

>1290_bases
ATGCTAAAAACTAAAAATATTTTTATAGTTTTTTTTGTTGTATTGGCTTTGATTTTTGGGTTTATTTTTTATACTTTTAC
TAATTCTTATCTTAATTTCTTGCTTATAAAACAATATGAACAAAAAATCAAAAGCCTTGATGATGTTTTAAAATTTTCTC
TCTTAGAGCATTTAAATGATGCTAATATCAAGGATTTTGCTAAAGATACTAGGGCTGATTTTATTATCCTAAACAATGAT
ATGAAAATAAGTTCTGTAAAAAATCCTGATTTTTTTTCTAATCTTAAAGAAGGAGAAATTTTAAATTTCAATTCAAAAAA
AATTCTCACTAAAAGCTTTATTTGCAAAGGATATAAATATATTATTATTGTTTATCCTCGTTTTTTAGATTTAGAACTTT
TTTGGACAAAAATGGCAATCGGTTTTGGAGTATGCTTGCTGTTTGTTTTTATTTTAATGTTGTTGTTAGGTAGAAGAATA
GAGAAAAATTTTAATAAAATTTTGGATTTTTTGGATTCTATAGGGGATCATAAAGTTGTTATATTAGAAAAAGGAATGTT
TAAAGAATTTAATTTACTAAATGAGAAACTTTTAAAAACTAAGGATAAAATTCTAAAGAATACCCAAAAAAATAAAAAAC
AAAGCGATAAAATCACTTTAAAAAATACTCAGCTTGCTAGCGTGATTTCTGCTATTTCTCATGAACTTAAAAATCCATTA
AGCGTGATTGATCTTAGCTTAGAGATGCTAAAAGATGAGAAATTGGAAGATAAAAAATTAAAAAAGGAATTACTAGAAAA
AATTTCACGTCAAAGCGTTAAACTTAATGCTTTAACCCATAAGCTTAATTTTGTTTTTAATCTTAATAGTGAAGCCTTGC
AGATGCAAGAATTCGATCTTTTTTCTCTATGTGAAAAAATCACTAAAAACCCAGGCTTTGAAAGAGTTGCATTGCAAGGT
AAAAGCACGAAAGTTAAGGCTGATGAATTTTTAATCGAGCAAGTGATTATAAATTTGCTTTCTAATGCTTTAAAATATAG
TCAAAAAAAAGTCATTTTAACGGCAAGAGATCAAAAGATAATAGTGCAAGATTTTGGAAAAGGTATAGAAGAAGATAAAA
TAAAATTGATTACAAAAAAATTTTATAAAATTGATGTAAAAAGTAATAATTCTTTTGGTTTGGGACTTTTTTTAGTAAAG
AAAATTTTAAATATACATAAAAGTTATCTTGAAATTTCTAGCACTTTAGGTTATGGTTCTAGTTTTAGCTTTAAACTCAG
TCAAGGATAA

Upstream 100 bases:

>100_bases
CAAGTGATAAAACAATCAATATAGCTCTAACAAGACTTAGAAATAAATTTCCAAAACTAAAAGATCATATTATAAGTGTT
AGGGGTATTGGCTATAAATT

Downstream 100 bases:

>100_bases
AAAATGGCTCTTATAGATTTAATTGAAGCTTCAAAAAAATTTGGAGACAAAATAGTTTTAAATGAAGTAAATTTTAGCGC
AAACGAGGGAGAAAAGATTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYEQKIKSLDDVLKFSLLEHLNDANIKDFAKDTRADFIILNND
MKISSVKNPDFFSNLKEGEILNFNSKKILTKSFICKGYKYIIIVYPRFLDLELFWTKMAIGFGVCLLFVFILMLLLGRRI
EKNFNKILDFLDSIGDHKVVILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSDKITLKNTQLASVISAISHELKNPL
SVIDLSLEMLKDEKLEDKKLKKELLEKISRQSVKLNALTHKLNFVFNLNSEALQMQEFDLFSLCEKITKNPGFERVALQG
KSTKVKADEFLIEQVIINLLSNALKYSQKKVILTARDQKIIVQDFGKGIEEDKIKLITKKFYKIDVKSNNSFGLGLFLVK
KILNIHKSYLEISSTLGYGSSFSFKLSQG

Sequences:

>Translated_429_residues
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYEQKIKSLDDVLKFSLLEHLNDANIKDFAKDTRADFIILNND
MKISSVKNPDFFSNLKEGEILNFNSKKILTKSFICKGYKYIIIVYPRFLDLELFWTKMAIGFGVCLLFVFILMLLLGRRI
EKNFNKILDFLDSIGDHKVVILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSDKITLKNTQLASVISAISHELKNPL
SVIDLSLEMLKDEKLEDKKLKKELLEKISRQSVKLNALTHKLNFVFNLNSEALQMQEFDLFSLCEKITKNPGFERVALQG
KSTKVKADEFLIEQVIINLLSNALKYSQKKVILTARDQKIIVQDFGKGIEEDKIKLITKKFYKIDVKSNNSFGLGLFLVK
KILNIHKSYLEISSTLGYGSSFSFKLSQG
>Mature_429_residues
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYEQKIKSLDDVLKFSLLEHLNDANIKDFAKDTRADFIILNND
MKISSVKNPDFFSNLKEGEILNFNSKKILTKSFICKGYKYIIIVYPRFLDLELFWTKMAIGFGVCLLFVFILMLLLGRRI
EKNFNKILDFLDSIGDHKVVILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSDKITLKNTQLASVISAISHELKNPL
SVIDLSLEMLKDEKLEDKKLKKELLEKISRQSVKLNALTHKLNFVFNLNSEALQMQEFDLFSLCEKITKNPGFERVALQG
KSTKVKADEFLIEQVIINLLSNALKYSQKKVILTARDQKIIVQDFGKGIEEDKIKLITKKFYKIDVKSNNSFGLGLFLVK
KILNIHKSYLEISSTLGYGSSFSFKLSQG

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=217, Percent_Identity=27.1889400921659, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=25.2100840336134, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=214, Percent_Identity=27.1028037383178, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49613; Mature: 49613

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYEQKIKSLDDVLKFSLLEHLND
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANIKDFAKDTRADFIILNNDMKISSVKNPDFFSNLKEGEILNFNSKKILTKSFICKGYKY
CCHHHHHHHCCCCEEEEECCEEECCCCCCHHHHCCCCCCEECCCCCHHHHHHHHHCCCEE
IIIVYPRFLDLELFWTKMAIGFGVCLLFVFILMLLLGRRIEKNFNKILDFLDSIGDHKVV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSDKITLKNTQLASVISAISHELKNPL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCH
SVIDLSLEMLKDEKLEDKKLKKELLEKISRQSVKLNALTHKLNFVFNLNSEALQMQEFDL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEEECCHHHHHHHHCHH
FSLCEKITKNPGFERVALQGKSTKVKADEFLIEQVIINLLSNALKYSQKKVILTARDQKI
HHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
IVQDFGKGIEEDKIKLITKKFYKIDVKSNNSFGLGLFLVKKILNIHKSYLEISSTLGYGS
HHHHHCCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SFSFKLSQG
CEEEEECCC
>Mature Secondary Structure
MLKTKNIFIVFFVVLALIFGFIFYTFTNSYLNFLLIKQYEQKIKSLDDVLKFSLLEHLND
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ANIKDFAKDTRADFIILNNDMKISSVKNPDFFSNLKEGEILNFNSKKILTKSFICKGYKY
CCHHHHHHHCCCCEEEEECCEEECCCCCCHHHHCCCCCCEECCCCCHHHHHHHHHCCCEE
IIIVYPRFLDLELFWTKMAIGFGVCLLFVFILMLLLGRRIEKNFNKILDFLDSIGDHKVV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ILEKGMFKEFNLLNEKLLKTKDKILKNTQKNKKQSDKITLKNTQLASVISAISHELKNPL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCH
SVIDLSLEMLKDEKLEDKKLKKELLEKISRQSVKLNALTHKLNFVFNLNSEALQMQEFDL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHEEEEEEEECCHHHHHHHHCHH
FSLCEKITKNPGFERVALQGKSTKVKADEFLIEQVIINLLSNALKYSQKKVILTARDQKI
HHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
IVQDFGKGIEEDKIKLITKKFYKIDVKSNNSFGLGLFLVKKILNIHKSYLEISSTLGYGS
HHHHHCCCCCHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
SFSFKLSQG
CEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3550103; 9278503; 2187152; 8391104 [H]