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The map label for this gene is uup [H]

Identifier: 57237717

GI number: 57237717

Start: 904454

End: 906385

Strand: Reverse

Name: uup [H]

Synonym: CJE0967

Alternate gene names: 57237717

Gene position: 906385-904454 (Counterclockwise)

Preceding gene: 57237718

Following gene: 57237716

Centisome position: 50.98

GC content: 29.92

Gene sequence:

>1932_bases
ATGGCTCTTATAGATTTAATTGAAGCTTCAAAAAAATTTGGAGACAAAATAGTTTTAAATGAAGTAAATTTTAGCGCAAA
CGAGGGAGAAAAGATTGCTATTATAGGCAAAAATGGAGAAGGAAAATCTACTTTTTTAAAAACGCTTTTAGGCACACTTC
CTTTAGATAGCGGTAGAATAATAAGACAAAATGGAAAAAGCATAGCCATGCTTTCACAAACCGTTGATTTTAATGCAAAT
TTAAGCGTAAAAGAAGCCATCAAGCAAGAGCTTGTAGAAATTTACAATACCTTAGAAGAATATGAAATACTGCATAAAAA
ATTAGAAGAAGATCCTAGTAATAAAGATTATCTTCAAAAAATAGATACGCTTATGACTTTGATTGATAGTAAAGATGCTT
GGAGTATAGAATCTAAAATAATACGCGTTTTAAAAGAATTTAGTTTACTTGAGTATGAAAATCGCATTATATCTACTTTA
AGTGGTGGAGAAATACGCCGCGTTGGGCTTTGCATACTTTTACTAAAAAATCCTGATATTTTATTGCTTGATGAACCAAC
TAATCATTTAGATGTATATATGACAAGCTTTTTGGAAGAATTGCTAAAAAATTCAAAGATGTGTGTGATTTTTATTTCCC
ATGATAGATATTTTATTGACGCTATAGCACACAAGTGTGTAGAAGTAGAGCAGGGTAAGCTTAGTATTTTTAAAGGCGGA
TATGCAAACTATTTAGAGAAAAAAACACAAATTTTACAAAGCCTTACTAAGAGCCATGAAACTCTTTTAAAGCAATTAAA
AAGCGAAGAAGAATGGCTTAGAAGAGGGGTTAAAGCAAGACTTAAAAGAAATGAAGGACGAAAAGAACGCATTTTTAAAA
TGCGTGAAGAAGCGAAAAAAAATCCTGGGGCAATCAAACGCTTAAAACTTGAAATTTCAAGAGCGGCTTTAAATTTTAAT
GGAGAAAAAACGATCAATCGTAAAAAAATGCTTTTTGAGCTTAAAAATATAAGCAAAAATATAAACAATAAAAATCTTTT
TAAAGATTTTTCAACGCGTATTTTACAAGGTGAACGCATAGCTATCGTAGGAAGAAATGGTTGTGGAAAATCAACATTGT
TAAAAATTCTTCTAGGGCAAATAAAACAAGATAGCGGTGAAATAAAACGCGGAGAGCTTAAGATAGGATATTTTGATCAG
GCTAGAAGCTTGGTAAATTCTGATAAAAGCTTGCTTGAAATTTTTTGTCCCAATGGTGGAGATAGGGTTGAAGTTCGTGG
TAAAAATATGCATGTTTATGGATATTTGAAAAATTTTCTATTTCCTAAGGAATTTTTAGATAAAAGCGTGGCTCTTTTAA
GTGGCGGAGAGAAAAATCGCGTTGCTTTAGCCTTGCTTTTTATTAAAGAATATGATGTTTTGATTTTAGATGAGCCAACT
AATGATCTTGATATAGCTACGATTAATATATTAGAAGAATACTTACTTAGTTTTGAAGGGGCTATTTTGCTAGTATCACA
CGATAGATATTTTGTTGATAAAATCGCAACAAAACTTTATGCTTTTGAGGGAAATGGATATATAAATATTTTACACACTC
TTTATACTGAATATCTTGAAAATGAAAAAGAAATTGAAGAATTGGATAATTTTGCTTTAGAGCTTCAAACCCAAGAGCAA
AATAATAACCAAAAAGAAAAAAGCTCCAAAAAATTGAGCTACAAAGAAAATGAGATATTAAAAAACCATCCTGAAAAAAT
AGATTTTTTAGAGCAAAAGATAGCTAAATTAAATCAAAATTTATCCGATCCAAATGTATATCAAGAAATAGGTATTAACA
AGCTTTATCAAGAGCTTGAAGTAATGCAAAAAGAACTTGAAATTCTAGAAAATGAGTATTTTTTAGTATTAGAGAAAAGC
GAGAATTTATAA

Upstream 100 bases:

>100_bases
AGTAAAGAAAATTTTAAATATACATAAAAGTTATCTTGAAATTTCTAGCACTTTAGGTTATGGTTCTAGTTTTAGCTTTA
AACTCAGTCAAGGATAAAAA

Downstream 100 bases:

>100_bases
TTAAAGAGATTTTATATTTTTTATTCTATGGAGCGGGAAACGAGATTCGAACCCGCGACCCCAACCTTGGCAAGGTTGTG
CTCTACCCCTGAGCTATTCC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MALIDLIEASKKFGDKIVLNEVNFSANEGEKIAIIGKNGEGKSTFLKTLLGTLPLDSGRIIRQNGKSIAMLSQTVDFNAN
LSVKEAIKQELVEIYNTLEEYEILHKKLEEDPSNKDYLQKIDTLMTLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTL
SGGEIRRVGLCILLLKNPDILLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
YANYLEKKTQILQSLTKSHETLLKQLKSEEEWLRRGVKARLKRNEGRKERIFKMREEAKKNPGAIKRLKLEISRAALNFN
GEKTINRKKMLFELKNISKNINNKNLFKDFSTRILQGERIAIVGRNGCGKSTLLKILLGQIKQDSGEIKRGELKIGYFDQ
ARSLVNSDKSLLEIFCPNGGDRVEVRGKNMHVYGYLKNFLFPKEFLDKSVALLSGGEKNRVALALLFIKEYDVLILDEPT
NDLDIATINILEEYLLSFEGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLENEKEIEELDNFALELQTQEQ
NNNQKEKSSKKLSYKENEILKNHPEKIDFLEQKIAKLNQNLSDPNVYQEIGINKLYQELEVMQKELEILENEYFLVLEKS
ENL

Sequences:

>Translated_643_residues
MALIDLIEASKKFGDKIVLNEVNFSANEGEKIAIIGKNGEGKSTFLKTLLGTLPLDSGRIIRQNGKSIAMLSQTVDFNAN
LSVKEAIKQELVEIYNTLEEYEILHKKLEEDPSNKDYLQKIDTLMTLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTL
SGGEIRRVGLCILLLKNPDILLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
YANYLEKKTQILQSLTKSHETLLKQLKSEEEWLRRGVKARLKRNEGRKERIFKMREEAKKNPGAIKRLKLEISRAALNFN
GEKTINRKKMLFELKNISKNINNKNLFKDFSTRILQGERIAIVGRNGCGKSTLLKILLGQIKQDSGEIKRGELKIGYFDQ
ARSLVNSDKSLLEIFCPNGGDRVEVRGKNMHVYGYLKNFLFPKEFLDKSVALLSGGEKNRVALALLFIKEYDVLILDEPT
NDLDIATINILEEYLLSFEGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLENEKEIEELDNFALELQTQEQ
NNNQKEKSSKKLSYKENEILKNHPEKIDFLEQKIAKLNQNLSDPNVYQEIGINKLYQELEVMQKELEILENEYFLVLEKS
ENL
>Mature_642_residues
ALIDLIEASKKFGDKIVLNEVNFSANEGEKIAIIGKNGEGKSTFLKTLLGTLPLDSGRIIRQNGKSIAMLSQTVDFNANL
SVKEAIKQELVEIYNTLEEYEILHKKLEEDPSNKDYLQKIDTLMTLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTLS
GGEIRRVGLCILLLKNPDILLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGGY
ANYLEKKTQILQSLTKSHETLLKQLKSEEEWLRRGVKARLKRNEGRKERIFKMREEAKKNPGAIKRLKLEISRAALNFNG
EKTINRKKMLFELKNISKNINNKNLFKDFSTRILQGERIAIVGRNGCGKSTLLKILLGQIKQDSGEIKRGELKIGYFDQA
RSLVNSDKSLLEIFCPNGGDRVEVRGKNMHVYGYLKNFLFPKEFLDKSVALLSGGEKNRVALALLFIKEYDVLILDEPTN
DLDIATINILEEYLLSFEGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLENEKEIEELDNFALELQTQEQN
NNQKEKSSKKLSYKENEILKNHPEKIDFLEQKIAKLNQNLSDPNVYQEIGINKLYQELEVMQKELEILENEYFLVLEKSE
NL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=532, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI10947135, Length=522, Percent_Identity=28.1609195402299, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI69354671, Length=522, Percent_Identity=28.1609195402299, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI27881506, Length=532, Percent_Identity=27.4436090225564, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI10947137, Length=532, Percent_Identity=27.6315789473684, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI108773784, Length=524, Percent_Identity=23.6641221374046, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI108773782, Length=524, Percent_Identity=23.6641221374046, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI1787182, Length=632, Percent_Identity=36.2341772151899, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI2367384, Length=538, Percent_Identity=33.457249070632, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI1789751, Length=627, Percent_Identity=28.548644338118, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1787041, Length=523, Percent_Identity=29.8279158699809, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1788506, Length=544, Percent_Identity=24.2647058823529, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081834, Length=223, Percent_Identity=31.390134529148, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788225, Length=263, Percent_Identity=25.8555133079848, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1789593, Length=240, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789672, Length=236, Percent_Identity=22.8813559322034, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994883, Length=242, Percent_Identity=27.6859504132231, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786703, Length=176, Percent_Identity=34.0909090909091, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786872, Length=235, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788897, Length=237, Percent_Identity=25.7383966244726, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786698, Length=212, Percent_Identity=30.6603773584906, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790544, Length=234, Percent_Identity=22.6495726495727, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790467, Length=166, Percent_Identity=29.5180722891566, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1787029, Length=213, Percent_Identity=26.2910798122066, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=528, Percent_Identity=26.7045454545455, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17555318, Length=528, Percent_Identity=27.4621212121212, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=28.6792452830189, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17555800, Length=204, Percent_Identity=26.9607843137255, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17552232, Length=205, Percent_Identity=27.3170731707317, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=534, Percent_Identity=27.5280898876405, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6321121, Length=542, Percent_Identity=26.7527675276753, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6325030, Length=255, Percent_Identity=29.0196078431373, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323278, Length=397, Percent_Identity=26.7002518891688, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324314, Length=399, Percent_Identity=24.0601503759398, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666836, Length=562, Percent_Identity=29.1814946619217, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24641342, Length=541, Percent_Identity=27.7264325323475, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24642252, Length=524, Percent_Identity=27.4809160305344, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI18859989, Length=524, Percent_Identity=27.4809160305344, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24661270, Length=528, Percent_Identity=24.2424242424242, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355589, Length=528, Percent_Identity=24.2424242424242, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI116007328, Length=193, Percent_Identity=27.979274611399, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574150, Length=193, Percent_Identity=27.979274611399, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221500365, Length=169, Percent_Identity=31.9526627218935, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=169, Percent_Identity=31.9526627218935, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 74018; Mature: 73886

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIDLIEASKKFGDKIVLNEVNFSANEGEKIAIIGKNGEGKSTFLKTLLGTLPLDSGRI
CCHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCE
IRQNGKSIAMLSQTVDFNANLSVKEAIKQELVEIYNTLEEYEILHKKLEEDPSNKDYLQK
EECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IDTLMTLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTLSGGEIRRVGLCILLLKNPDI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCE
LLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
EEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCC
YANYLEKKTQILQSLTKSHETLLKQLKSEEEWLRRGVKARLKRNEGRKERIFKMREEAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
NPGAIKRLKLEISRAALNFNGEKTINRKKMLFELKNISKNINNKNLFKDFSTRILQGERI
CCCHHHHHHHEEEHHHCCCCCCHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEE
AIVGRNGCGKSTLLKILLGQIKQDSGEIKRGELKIGYFDQARSLVNSDKSLLEIFCPNGG
EEEECCCCCHHHHHHHHHHHHCCCCCCCEECEEEEEEHHHHHHHHCCCCCEEEEECCCCC
DRVEVRGKNMHVYGYLKNFLFPKEFLDKSVALLSGGEKNRVALALLFIKEYDVLILDEPT
CEEEEECCCEEEEEEHHHCCCCHHHHCCHHHHHCCCCCCCEEEEEEEEECCCEEEEECCC
NDLDIATINILEEYLLSFEGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLE
CCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEEECCCEEEHHHHHHHHHHC
NEKEIEELDNFALELQTQEQNNNQKEKSSKKLSYKENEILKNHPEKIDFLEQKIAKLNQN
CHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHCC
LSDPNVYQEIGINKLYQELEVMQKELEILENEYFLVLEKSENL
CCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
>Mature Secondary Structure 
ALIDLIEASKKFGDKIVLNEVNFSANEGEKIAIIGKNGEGKSTFLKTLLGTLPLDSGRI
CHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCE
IRQNGKSIAMLSQTVDFNANLSVKEAIKQELVEIYNTLEEYEILHKKLEEDPSNKDYLQK
EECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IDTLMTLIDSKDAWSIESKIIRVLKEFSLLEYENRIISTLSGGEIRRVGLCILLLKNPDI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCE
LLLDEPTNHLDVYMTSFLEELLKNSKMCVIFISHDRYFIDAIAHKCVEVEQGKLSIFKGG
EEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCC
YANYLEKKTQILQSLTKSHETLLKQLKSEEEWLRRGVKARLKRNEGRKERIFKMREEAKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
NPGAIKRLKLEISRAALNFNGEKTINRKKMLFELKNISKNINNKNLFKDFSTRILQGERI
CCCHHHHHHHEEEHHHCCCCCCHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEE
AIVGRNGCGKSTLLKILLGQIKQDSGEIKRGELKIGYFDQARSLVNSDKSLLEIFCPNGG
EEEECCCCCHHHHHHHHHHHHCCCCCCCEECEEEEEEHHHHHHHHCCCCCEEEEECCCCC
DRVEVRGKNMHVYGYLKNFLFPKEFLDKSVALLSGGEKNRVALALLFIKEYDVLILDEPT
CEEEEECCCEEEEEEHHHCCCCHHHHCCHHHHHCCCCCCCEEEEEEEEECCCEEEEECCC
NDLDIATINILEEYLLSFEGAILLVSHDRYFVDKIATKLYAFEGNGYINILHTLYTEYLE
CCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEEEECCCEEEHHHHHHHHHHC
NEKEIEELDNFALELQTQEQNNNQKEKSSKKLSYKENEILKNHPEKIDFLEQKIAKLNQN
CHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHCC
LSDPNVYQEIGINKLYQELEVMQKELEILENEYFLVLEKSENL
CCCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]