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The map label for this gene is trxB [H]

Identifier: 57237154

GI number: 57237154

Start: 149400

End: 150338

Strand: Reverse

Name: trxB [H]

Synonym: CJE0142

Alternate gene names: 57237154

Gene position: 150338-149400 (Counterclockwise)

Preceding gene: 57237155

Following gene: 57237150

Centisome position: 8.46

GC content: 35.57

Gene sequence:

>939_bases
ATGTTAGATGTAGCAATCATAGGTGGAGGTCCTGCTGGACTTAGTGCTGGACTTTATGCAACTAGAGGTGGTCTTAAGAA
TGTAGTAATGTTTGAAAAAGGTATGCCTGGTGGACAAATTACCTCAAGTTCTGAAATAGAAAATTATCCAGGTGTAGCCC
AAGTTATGGATGGAATTTCTTTTATGACTCCTTGGAATGAACAATGTATGCGTTTTGGTTTAAAACATGAAATGGTTGGA
GTAGAACAAATTTTAAAAAATAGTGATGGAAGTTTTACCATCAAATTAGAAGGTGGTAAAACAGAACTTGCTAAAGCTGT
GATAGTTTGTACAGGCTCAGCTCCAAAAAAAGCAGGTTTTAAGGGCGAAGATAAATTTTTTGGAAAAGGTGTAAGCACTT
GTGCAACTTGTGATGGATTTTTTTATAAAAATAAAGAAGTTGCAGTTTTAGGTGGTGGAGATACGGCTTTAGAAGAAGCT
TTATATCTAGCAAATATTTGTTCTAAGGTTTATCTTATCCACCGCAGAGATGAGTTTAGAGCAGCTCCATCTACAGTAGA
AAAAGTTAAGAAAAACGAAAAAATAGAACTCATTACTAGCGCAAGTGTAGATGAAGTATATGGTGATAAAATGGGTGTTA
CTGGGGTAAAAGTAAAATTAAAAGATGGTAGTATTAGAGATTTAAATGTTCCAGGAATTTTTACTTTTGTTGGTCTTAAT
GTAAGAAATGAAATTTTAAAACAAGACGATGGTAAGTTTTTATGCAATATGGAAGAAGGTGGGCAAGTAAGTGTTGATCT
TAAAATGCAAACTAGCGTTGCTGGACTTTTTGCCGCAGGGGACCTTAGAAAAGATGCGCCTAAGCAAGTTATTTGTGCTG
CAGGTGATGGAGCTGTAGCTGCATTAAGTGCTATGGCTTATATAGAAAGCTTGCATTAA

Upstream 100 bases:

>100_bases
AAATTTCAAATTTATACTAAATAATAATTTTTATTAACTACTATTAAGAATAATTTTTATATCATTATTAATAATAAAAT
TCAATATAAAGGAAATATAA

Downstream 100 bases:

>100_bases
GATTTTATAAAGTTGCTAAAAGCAACTTTATTTTTATTTAGCTTCCTATCACTCCACCATCAAGTTTTCTTATCATCATT
ACACTTGATCTTGGCGTTTT

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MLDVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYPGVAQVMDGISFMTPWNEQCMRFGLKHEMVG
VEQILKNSDGSFTIKLEGGKTELAKAVIVCTGSAPKKAGFKGEDKFFGKGVSTCATCDGFFYKNKEVAVLGGGDTALEEA
LYLANICSKVYLIHRRDEFRAAPSTVEKVKKNEKIELITSASVDEVYGDKMGVTGVKVKLKDGSIRDLNVPGIFTFVGLN
VRNEILKQDDGKFLCNMEEGGQVSVDLKMQTSVAGLFAAGDLRKDAPKQVICAAGDGAVAALSAMAYIESLH

Sequences:

>Translated_312_residues
MLDVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYPGVAQVMDGISFMTPWNEQCMRFGLKHEMVG
VEQILKNSDGSFTIKLEGGKTELAKAVIVCTGSAPKKAGFKGEDKFFGKGVSTCATCDGFFYKNKEVAVLGGGDTALEEA
LYLANICSKVYLIHRRDEFRAAPSTVEKVKKNEKIELITSASVDEVYGDKMGVTGVKVKLKDGSIRDLNVPGIFTFVGLN
VRNEILKQDDGKFLCNMEEGGQVSVDLKMQTSVAGLFAAGDLRKDAPKQVICAAGDGAVAALSAMAYIESLH
>Mature_312_residues
MLDVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYPGVAQVMDGISFMTPWNEQCMRFGLKHEMVG
VEQILKNSDGSFTIKLEGGKTELAKAVIVCTGSAPKKAGFKGEDKFFGKGVSTCATCDGFFYKNKEVAVLGGGDTALEEA
LYLANICSKVYLIHRRDEFRAAPSTVEKVKKNEKIELITSASVDEVYGDKMGVTGVKVKLKDGSIRDLNVPGIFTFVGLN
VRNEILKQDDGKFLCNMEEGGQVSVDLKMQTSVAGLFAAGDLRKDAPKQVICAAGDGAVAALSAMAYIESLH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=40.1253918495298, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI87081763, Length=323, Percent_Identity=33.7461300309598, Blast_Score=128, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=34.7826086956522, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=32.8125, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33161; Mature: 33161

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYPGVAQVMDGIS
CEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCH
FMTPWNEQCMRFGLKHEMVGVEQILKNSDGSFTIKLEGGKTELAKAVIVCTGSAPKKAGF
HCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHHEEEEEEEEECCCCCCCCC
KGEDKFFGKGVSTCATCDGFFYKNKEVAVLGGGDTALEEALYLANICSKVYLIHRRDEFR
CCCCCHHCCCCCHHEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEEEECHHHC
AAPSTVEKVKKNEKIELITSASVDEVYGDKMGVTGVKVKLKDGSIRDLNVPGIFTFVGLN
CCHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEEECCCCEEECCCCCEEEEEECC
VRNEILKQDDGKFLCNMEEGGQVSVDLKMQTSVAGLFAAGDLRKDAPKQVICAAGDGAVA
HHHHHHHCCCCCEEEEECCCCEEEEEEEEECCHHEEEEECCCCCCCCCEEEEECCCCHHH
ALSAMAYIESLH
HHHHHHHHHHCC
>Mature Secondary Structure
MLDVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSEIENYPGVAQVMDGIS
CEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCH
FMTPWNEQCMRFGLKHEMVGVEQILKNSDGSFTIKLEGGKTELAKAVIVCTGSAPKKAGF
HCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHHEEEEEEEEECCCCCCCCC
KGEDKFFGKGVSTCATCDGFFYKNKEVAVLGGGDTALEEALYLANICSKVYLIHRRDEFR
CCCCCHHCCCCCHHEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEEEECHHHC
AAPSTVEKVKKNEKIELITSASVDEVYGDKMGVTGVKVKLKDGSIRDLNVPGIFTFVGLN
CCHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEEECCCCEEECCCCCEEEEEECC
VRNEILKQDDGKFLCNMEEGGQVSVDLKMQTSVAGLFAAGDLRKDAPKQVICAAGDGAVA
HHHHHHHCCCCCEEEEECCCCEEEEEEEEECCHHEEEEECCCCCCCCCEEEEECCCCHHH
ALSAMAYIESLH
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]