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The map label for this gene is adcA [H]

Identifier: 57237150

GI number: 57237150

Start: 144318

End: 145208

Strand: Reverse

Name: adcA [H]

Synonym: CJE0138

Alternate gene names: 57237150

Gene position: 145208-144318 (Counterclockwise)

Preceding gene: 57237154

Following gene: 57237149

Centisome position: 8.17

GC content: 26.37

Gene sequence:

>891_bases
TTGAAAAAAATTATATTATTTATCTTATCTTTAGGGATATTTTATACTTTCACACAAGCTAAAAATTTAGAGCAAGAACA
AAATACTAGTAGCAATTTAGTTAGTGTCAGTATAGCACCTCAAGCATTTTTTGTTAAAAAAATAGCTGCAAATACTCTAG
ATATCAATGTTATTTTGCCCCCAAATAGCAATGAGCATAATTTTGAATTTAAACCAAGTACTATGAAAAAACTTGAAAAA
AGTGATATTTATTTCACTATAGGCTTAGAATTTGAAAAAGTTTTTACGGATAAATTTAAACAAAATTTTCCAAAACTTCA
AGTTATAAATATGCAAAAAAACATAGCTTTGATTCAAACTCATGATACACACGAACACTCTCATGAACATGAACACCACG
AACATGAGCATTTTGATCCTCATACTTGGCTAGATCCTATTTTAGTCCAAACTATGGCTTTAAATATTTATGACACCTTA
ATTCAAAAATATCCACAAAATGAAAATTTATATAAAGAAAATTTAGATAAATTTTTAGCAGAATTAGATAGTTTAAATTT
ACAAATTGCCTCAAAATTAGAAAAATTAAAAAATAGAGAATTTGTAGTTTATCATCCTTCTTGGACATATTTTGCAAAAC
GCTATAATCTTACGCAAATTCCTGTAGAAATTTTAGGCAAGGAACCAAAAAGCAAAGATTTGCAAAAACTTATCACTCTA
ATGAAAAATAAAAATTTAAAAGTCATTTTTGTTCAAAATGGTTTCCCTGAAAATGCAGCAAAAACACTTGCTAAAGAATG
TGATGCAAAAATTTACAAAATAGATCATTTATCTTATGATTGGGAAAATGAGCTTTTAAAAACTGCTGATGCCTTTTCTC
ATAATTTATAA

Upstream 100 bases:

>100_bases
TATATTTATTATTTTTATTTAAATAAATATCGCTTCGAAAATTCTATGTATTAAGCTTAATATCGTTATAATTTAAAAAA
TTTATATCGAAGGAAATATT

Downstream 100 bases:

>100_bases
TCAGGTTTTTTGATGCTTTTTTTTGAAATTTCTAATCTAAACTACGCTTATAATAATGAAATCATCTTAAAAAACATCAA
TCTTAGCTATGACAATAAAG

Product: cation ABC transporter periplasmic cation-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKKIILFILSLGIFYTFTQAKNLEQEQNTSSNLVSVSIAPQAFFVKKIAANTLDINVILPPNSNEHNFEFKPSTMKKLEK
SDIYFTIGLEFEKVFTDKFKQNFPKLQVINMQKNIALIQTHDTHEHSHEHEHHEHEHFDPHTWLDPILVQTMALNIYDTL
IQKYPQNENLYKENLDKFLAELDSLNLQIASKLEKLKNREFVVYHPSWTYFAKRYNLTQIPVEILGKEPKSKDLQKLITL
MKNKNLKVIFVQNGFPENAAKTLAKECDAKIYKIDHLSYDWENELLKTADAFSHNL

Sequences:

>Translated_296_residues
MKKIILFILSLGIFYTFTQAKNLEQEQNTSSNLVSVSIAPQAFFVKKIAANTLDINVILPPNSNEHNFEFKPSTMKKLEK
SDIYFTIGLEFEKVFTDKFKQNFPKLQVINMQKNIALIQTHDTHEHSHEHEHHEHEHFDPHTWLDPILVQTMALNIYDTL
IQKYPQNENLYKENLDKFLAELDSLNLQIASKLEKLKNREFVVYHPSWTYFAKRYNLTQIPVEILGKEPKSKDLQKLITL
MKNKNLKVIFVQNGFPENAAKTLAKECDAKIYKIDHLSYDWENELLKTADAFSHNL
>Mature_296_residues
MKKIILFILSLGIFYTFTQAKNLEQEQNTSSNLVSVSIAPQAFFVKKIAANTLDINVILPPNSNEHNFEFKPSTMKKLEK
SDIYFTIGLEFEKVFTDKFKQNFPKLQVINMQKNIALIQTHDTHEHSHEHEHHEHEHFDPHTWLDPILVQTMALNIYDTL
IQKYPQNENLYKENLDKFLAELDSLNLQIASKLEKLKNREFVVYHPSWTYFAKRYNLTQIPVEILGKEPKSKDLQKLITL
MKNKNLKVIFVQNGFPENAAKTLAKECDAKIYKIDHLSYDWENELLKTADAFSHNL

Specific function: Part of the ATP-driven transport system AdcABC for zinc [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=257, Percent_Identity=24.9027237354086, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 34663; Mature: 34663

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIILFILSLGIFYTFTQAKNLEQEQNTSSNLVSVSIAPQAFFVKKIAANTLDINVILP
CHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCHHHHHHHHHCCEEEEEEEEC
PNSNEHNFEFKPSTMKKLEKSDIYFTIGLEFEKVFTDKFKQNFPKLQVINMQKNIALIQT
CCCCCCCEEECCHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCEEEEEECCCEEEEEE
HDTHEHSHEHEHHEHEHFDPHTWLDPILVQTMALNIYDTLIQKYPQNENLYKENLDKFLA
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ELDSLNLQIASKLEKLKNREFVVYHPSWTYFAKRYNLTQIPVEILGKEPKSKDLQKLITL
HHHHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHH
MKNKNLKVIFVQNGFPENAAKTLAKECDAKIYKIDHLSYDWENELLKTADAFSHNL
HCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIILFILSLGIFYTFTQAKNLEQEQNTSSNLVSVSIAPQAFFVKKIAANTLDINVILP
CHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCHHHHHHHHHCCEEEEEEEEC
PNSNEHNFEFKPSTMKKLEKSDIYFTIGLEFEKVFTDKFKQNFPKLQVINMQKNIALIQT
CCCCCCCEEECCHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCCCEEEEEECCCEEEEEE
HDTHEHSHEHEHHEHEHFDPHTWLDPILVQTMALNIYDTLIQKYPQNENLYKENLDKFLA
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ELDSLNLQIASKLEKLKNREFVVYHPSWTYFAKRYNLTQIPVEILGKEPKSKDLQKLITL
HHHHCCHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHH
MKNKNLKVIFVQNGFPENAAKTLAKECDAKIYKIDHLSYDWENELLKTADAFSHNL
HCCCCEEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]