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The map label for this gene is ung [H]

Identifier: 57237093

GI number: 57237093

Start: 94116

End: 94811

Strand: Reverse

Name: ung [H]

Synonym: CJE0081

Alternate gene names: 57237093

Gene position: 94811-94116 (Counterclockwise)

Preceding gene: 57237130

Following gene: 57237092

Centisome position: 5.33

GC content: 29.02

Gene sequence:

>696_bases
ATGGAAGAAATTACAATAAACATAGATAAGATTAAAATAAATGATGACTGGAAAGAATTTTTAAGAGACGAATTTCAAAA
AAAATATTTTCTAGAAATCAAAAAACAATACCTAAATGCGATTAATCAAAATATAGTTATTTATCCGCCTGCAAATTTAA
TCTTTAATGCTTTTAATTTATGTCCTTTAAAAGAAATTAAAATTATTATCCTAGGACAAGATCCTTATCATCAACCAAAT
CAAGCAATGGGGCTTAGTTTTTCGGTTCCAAAAAATGTAAAAATCCCACCAAGTCTTAATAATATTTTTAAAGAATTGCA
AAATGATTTAAACATCACTCCAGCAAAAAGCGGAGATTTAAGCTCTTGGGCAAAACAAGGAGTTTTGCTCTTAAATTCTA
TTCTTAGCGTTGAAGCAAATAAAGCAGCTAGCCATAGTTCGTGGGGTTGGCAAGAATTTAGTGATGCTATAATACATAAA
TTAAGTAATGAAAAATCAGGGCTTGTTTTTATGCTTTGGGGAAATTACGCAAAAAACAAGGAGATTTTGATTGATAATAC
TAAGCATTTGATTTTAAAAGCAGCTCACCCAAGCCCTTTAGCTAGAACAGGATTTTTAGGTTGTAAGCATTTTTCAAAGG
CTAATGAATTTTTAAAAAAAGTTGGTAAAATTCCTATAGATTGGAAAATAGTTTAA

Upstream 100 bases:

>100_bases
TAATATAAAAAATTTTATTTACTTCAAAAAAAATTAATATATTTTTGCAAGCTTTTTTGTTAGAATAAAATTTTTAATAA
TTTAAATAATTAGGGATAAT

Downstream 100 bases:

>100_bases
AAAATTATTTTAAACTTTAATAAAAATATTAAAATATATTTATTTATTTAAAAATAAATCATATTTCTATGAAATATATT
GTAATAAAACGACTCAAAAA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MEEITINIDKIKINDDWKEFLRDEFQKKYFLEIKKQYLNAINQNIVIYPPANLIFNAFNLCPLKEIKIIILGQDPYHQPN
QAMGLSFSVPKNVKIPPSLNNIFKELQNDLNITPAKSGDLSSWAKQGVLLLNSILSVEANKAASHSSWGWQEFSDAIIHK
LSNEKSGLVFMLWGNYAKNKEILIDNTKHLILKAAHPSPLARTGFLGCKHFSKANEFLKKVGKIPIDWKIV

Sequences:

>Translated_231_residues
MEEITINIDKIKINDDWKEFLRDEFQKKYFLEIKKQYLNAINQNIVIYPPANLIFNAFNLCPLKEIKIIILGQDPYHQPN
QAMGLSFSVPKNVKIPPSLNNIFKELQNDLNITPAKSGDLSSWAKQGVLLLNSILSVEANKAASHSSWGWQEFSDAIIHK
LSNEKSGLVFMLWGNYAKNKEILIDNTKHLILKAAHPSPLARTGFLGCKHFSKANEFLKKVGKIPIDWKIV
>Mature_231_residues
MEEITINIDKIKINDDWKEFLRDEFQKKYFLEIKKQYLNAINQNIVIYPPANLIFNAFNLCPLKEIKIIILGQDPYHQPN
QAMGLSFSVPKNVKIPPSLNNIFKELQNDLNITPAKSGDLSSWAKQGVLLLNSILSVEANKAASHSSWGWQEFSDAIIHK
LSNEKSGLVFMLWGNYAKNKEILIDNTKHLILKAAHPSPLARTGFLGCKHFSKANEFLKKVGKIPIDWKIV

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=221, Percent_Identity=48.868778280543, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI6224979, Length=221, Percent_Identity=48.868778280543, Blast_Score=232, Evalue=3e-61,
Organism=Escherichia coli, GI1788934, Length=217, Percent_Identity=47.4654377880184, Blast_Score=222, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17556304, Length=229, Percent_Identity=44.9781659388646, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6323620, Length=237, Percent_Identity=41.3502109704641, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 26327; Mature: 26327

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEITINIDKIKINDDWKEFLRDEFQKKYFLEIKKQYLNAINQNIVIYPPANLIFNAFNL
CCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCC
CPLKEIKIIILGQDPYHQPNQAMGLSFSVPKNVKIPPSLNNIFKELQNDLNITPAKSGDL
CCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
SSWAKQGVLLLNSILSVEANKAASHSSWGWQEFSDAIIHKLSNEKSGLVFMLWGNYAKNK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
EILIDNTKHLILKAAHPSPLARTGFLGCKHFSKANEFLKKVGKIPIDWKIV
EEEEECCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MEEITINIDKIKINDDWKEFLRDEFQKKYFLEIKKQYLNAINQNIVIYPPANLIFNAFNL
CCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCC
CPLKEIKIIILGQDPYHQPNQAMGLSFSVPKNVKIPPSLNNIFKELQNDLNITPAKSGDL
CCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCH
SSWAKQGVLLLNSILSVEANKAASHSSWGWQEFSDAIIHKLSNEKSGLVFMLWGNYAKNK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCC
EILIDNTKHLILKAAHPSPLARTGFLGCKHFSKANEFLKKVGKIPIDWKIV
EEEEECCCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA