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The map label for this gene is ftsK [H]

Identifier: 57234759

GI number: 57234759

Start: 415774

End: 418218

Strand: Direct

Name: ftsK [H]

Synonym: DET0439

Alternate gene names: 57234759

Gene position: 415774-418218 (Clockwise)

Preceding gene: 57234760

Following gene: 57234734

Centisome position: 28.29

GC content: 53.25

Gene sequence:

>2445_bases
ATGCCTAAAAAAGAAGACCCCAGAGACACCCTGCGGAATGCCCGCCCCAGAGCTAAATCTGCGGTTAAGGTAACTGCCCG
TCCGTTTAAGAAAACCGCTCCGGTACGCAGCAAGGCTAAAAAAACAGCTGCTAAGAAGGCTTTTTCAAATACCCCGGTCA
GAGGCGGGGCTTCCTGGCTTTGGGTTATGCTGATAGCCTCGGCTATGGCCTTTGTGGTCTGGCAGTGGGAAGGCGTAATG
GACTTTTTTGCCAATTTCGGCAGCGGTACGGCCGGATTGTTCGGCTGGGGGCTGCTGCTTATTCTTTTGGGTATTATCAT
AGCTATTGTGGCTCTCAGGTTTGACCAGATGTCCGAATGGGCTCACCGCTACCGCTTAAATCTCTGGAACAAATGGCTGG
GCGGGGTGGTGCTGATTCTGGCGGCCTGGGGTATGCTGGGCATGATGGATGCCGGCGGTGATATAGGTCTAAGCATACTT
GGCGGTAACGCTGATATAAACGGGTTTATGCGGGTGCTGGCCCTGATTGTACTGGGGGTTATCCTTATAGCTCCGGGTGC
AGTCTGGCGAAGCCTCAGCGGGCTTTTCAGGGGTATTTTCAGCCCCTCCCGCCGCTCTAATATGCCCGAAGTGGCCCGCC
TTGACCGTACGGTAGTCAGCCGCCCTGTATTCGGCGGTGATGAAGACCGTATTGATATGGGTGAAGAGGCCCGCAGGCCT
CTGCCTGAAAAAGCTGCCCCGAAGATAGAACTACCCTCTATAAAGCTGCCGTCTTTCGGCAAAGCTGAATCACGGGTAGT
AGAAGTAAAAAACCCGCTGGCGGCTAAAAGTACTCCCCAGACCGAGCTTCCCAATATGCCGCCGGAGACTGCCGCTAAAG
AACCTAAATCGGTTGATGAGCGCACTGATGCAGACCGCAAACAGATAGCTTCCGAAGTCTGGAAGAAATATGGTGAGGCT
GAGGGGATAGCCGAGGTGGATGGCTGGAAACTGCCGCCTATAGAAATGCTGGATAAAACTACCGAAATAGGTTTTTCGGA
AGCGGATAATCTGCAGCGGGCAAGGGCTATTGAAGAAGCCCTGGCCAGCTACGGGGTGGAGGGCAAGGTTATCCAGATAA
ATGCCGGTCCTACCGTTACCCAATTCGGGGTTGAACCGGGCTGGGACCGCAAGTTTAAAGAAGTTAAAGAGCGTGACAAA
GACGGGGAGACTGTTTCTCGCCAGGTGGAGGTTTCCAAGACAAGGGTCAAGGTTGACAGGATTGCCTCTCTGGCAAATGA
CCTGGCTCTGGCTTTGGCCGCCCCCAGTTTACGCATAGAAGCCCCGGTGCCGGGTAAATCCATAGTGGGTATAGAAGTGC
CCAACACTTCATTCGGGGTGGTATCTATGCGGAGCGTCATGGAGACCAATACTTTTCAGAAGATACTGGCCCGTTCACCC
CTGGCTCTGGCTTTGGGCAAAGGTGCAGGCGGTGAGGCTGTTTCGGGAGACCTTACCAAGATGCCCCATCTGCTTATTGC
CGGTGCTACCGGTTCGGGTAAGACAGTCTGTTTAAACTCTATTATCTGCTGTATGCTGCTTAACAATACGCCTTCCAGCG
TGAAGTTTATTATGATAGACCCCAAACGGGTAGAGCTGACCCCCTTTAACGGCTTGCCGCATCTGGCTACCCCGGTGATT
GTAGACGTGGAAAAAGCCCTTTCCGCCCTGCGCTGGCTGGCGGCCGAAATGGACCGCCGCTACCAGACACTGGCCGCCGC
CGGTTCGCGTAATATAGAGGGTTACAACAAGACCCGCATGGGTTCTGACCGGATGGCGTTTATTGTGCTGATAATAGATG
AGCTGGCTGACCTGATGATGGCCGGTTTTGATGAGGTTGAGCATATCCTCTGCCGTTTGGCCCAAATGGCCAGAGCAGTG
GGTATTCACCTGGTGGTGGCCACCCAGCGCCCGTCAGTAGATGTTATCACCGGGCTTATTAAGGCTAACTTCCCCACCCG
TATCAGTTTTGCGGTTACCTCTCAGGTGGATTCGCGGACTATTCTGGATATGGTGGGGGCGGAAAAACTGCTGGGGCGGG
GCGATATGCTTTATATGCCCACCGAGGCAGCCAAACCCAAACGCCTGCAGGGCTGTTATGTTTCGGATGCCGAGAGTGAA
CGCCTGATATATTTCTGGACCAACCAGAAAGATATTTCTCCGTCTGAGGCTTTGAAGGTTGAGGAGATTACCGCGCCGCC
GCCCGCCCCAAAAAGTAAAAGCAAAGACCCTTTGTTTGATGAGGCTATGGCACTTATATCAGAGCATAACAATATTATTT
CAGCCTCGTTTTTACAGAGGAAGATGCATATCGGTTACCCCAGAGCCGCCCGTTTGGCAGATGAACTGCGGGAAGCTATT
GAGGGTGATGACGGCAAAGCCGAAGTGCCTAAAGATGAGTATTAA

Upstream 100 bases:

>100_bases
GTCAAAGAAACGCTGAACAAGTTTTACTACGAGCAGACTAAACGGCGTCCCATGGTTATCCCGGTTATGGTAAAAGTGTA
GGTTTGCAGACGAGGTTAAT

Downstream 100 bases:

>100_bases
ATAAACAGCTTACTCTGTATTAAAAAAGCCCTGACTTAAATCAGGGCTTTTATTTGGTCTTTTTTTCAACAGCGTCTTTG
TAAACTCTGGCCAGACCTTT

Product: FtsK/SpoIIIE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 814; Mature: 813

Protein sequence:

>814_residues
MPKKEDPRDTLRNARPRAKSAVKVTARPFKKTAPVRSKAKKTAAKKAFSNTPVRGGASWLWVMLIASAMAFVVWQWEGVM
DFFANFGSGTAGLFGWGLLLILLGIIIAIVALRFDQMSEWAHRYRLNLWNKWLGGVVLILAAWGMLGMMDAGGDIGLSIL
GGNADINGFMRVLALIVLGVILIAPGAVWRSLSGLFRGIFSPSRRSNMPEVARLDRTVVSRPVFGGDEDRIDMGEEARRP
LPEKAAPKIELPSIKLPSFGKAESRVVEVKNPLAAKSTPQTELPNMPPETAAKEPKSVDERTDADRKQIASEVWKKYGEA
EGIAEVDGWKLPPIEMLDKTTEIGFSEADNLQRARAIEEALASYGVEGKVIQINAGPTVTQFGVEPGWDRKFKEVKERDK
DGETVSRQVEVSKTRVKVDRIASLANDLALALAAPSLRIEAPVPGKSIVGIEVPNTSFGVVSMRSVMETNTFQKILARSP
LALALGKGAGGEAVSGDLTKMPHLLIAGATGSGKTVCLNSIICCMLLNNTPSSVKFIMIDPKRVELTPFNGLPHLATPVI
VDVEKALSALRWLAAEMDRRYQTLAAAGSRNIEGYNKTRMGSDRMAFIVLIIDELADLMMAGFDEVEHILCRLAQMARAV
GIHLVVATQRPSVDVITGLIKANFPTRISFAVTSQVDSRTILDMVGAEKLLGRGDMLYMPTEAAKPKRLQGCYVSDAESE
RLIYFWTNQKDISPSEALKVEEITAPPPAPKSKSKDPLFDEAMALISEHNNIISASFLQRKMHIGYPRAARLADELREAI
EGDDGKAEVPKDEY

Sequences:

>Translated_814_residues
MPKKEDPRDTLRNARPRAKSAVKVTARPFKKTAPVRSKAKKTAAKKAFSNTPVRGGASWLWVMLIASAMAFVVWQWEGVM
DFFANFGSGTAGLFGWGLLLILLGIIIAIVALRFDQMSEWAHRYRLNLWNKWLGGVVLILAAWGMLGMMDAGGDIGLSIL
GGNADINGFMRVLALIVLGVILIAPGAVWRSLSGLFRGIFSPSRRSNMPEVARLDRTVVSRPVFGGDEDRIDMGEEARRP
LPEKAAPKIELPSIKLPSFGKAESRVVEVKNPLAAKSTPQTELPNMPPETAAKEPKSVDERTDADRKQIASEVWKKYGEA
EGIAEVDGWKLPPIEMLDKTTEIGFSEADNLQRARAIEEALASYGVEGKVIQINAGPTVTQFGVEPGWDRKFKEVKERDK
DGETVSRQVEVSKTRVKVDRIASLANDLALALAAPSLRIEAPVPGKSIVGIEVPNTSFGVVSMRSVMETNTFQKILARSP
LALALGKGAGGEAVSGDLTKMPHLLIAGATGSGKTVCLNSIICCMLLNNTPSSVKFIMIDPKRVELTPFNGLPHLATPVI
VDVEKALSALRWLAAEMDRRYQTLAAAGSRNIEGYNKTRMGSDRMAFIVLIIDELADLMMAGFDEVEHILCRLAQMARAV
GIHLVVATQRPSVDVITGLIKANFPTRISFAVTSQVDSRTILDMVGAEKLLGRGDMLYMPTEAAKPKRLQGCYVSDAESE
RLIYFWTNQKDISPSEALKVEEITAPPPAPKSKSKDPLFDEAMALISEHNNIISASFLQRKMHIGYPRAARLADELREAI
EGDDGKAEVPKDEY
>Mature_813_residues
PKKEDPRDTLRNARPRAKSAVKVTARPFKKTAPVRSKAKKTAAKKAFSNTPVRGGASWLWVMLIASAMAFVVWQWEGVMD
FFANFGSGTAGLFGWGLLLILLGIIIAIVALRFDQMSEWAHRYRLNLWNKWLGGVVLILAAWGMLGMMDAGGDIGLSILG
GNADINGFMRVLALIVLGVILIAPGAVWRSLSGLFRGIFSPSRRSNMPEVARLDRTVVSRPVFGGDEDRIDMGEEARRPL
PEKAAPKIELPSIKLPSFGKAESRVVEVKNPLAAKSTPQTELPNMPPETAAKEPKSVDERTDADRKQIASEVWKKYGEAE
GIAEVDGWKLPPIEMLDKTTEIGFSEADNLQRARAIEEALASYGVEGKVIQINAGPTVTQFGVEPGWDRKFKEVKERDKD
GETVSRQVEVSKTRVKVDRIASLANDLALALAAPSLRIEAPVPGKSIVGIEVPNTSFGVVSMRSVMETNTFQKILARSPL
ALALGKGAGGEAVSGDLTKMPHLLIAGATGSGKTVCLNSIICCMLLNNTPSSVKFIMIDPKRVELTPFNGLPHLATPVIV
DVEKALSALRWLAAEMDRRYQTLAAAGSRNIEGYNKTRMGSDRMAFIVLIIDELADLMMAGFDEVEHILCRLAQMARAVG
IHLVVATQRPSVDVITGLIKANFPTRISFAVTSQVDSRTILDMVGAEKLLGRGDMLYMPTEAAKPKRLQGCYVSDAESER
LIYFWTNQKDISPSEALKVEEITAPPPAPKSKSKDPLFDEAMALISEHNNIISASFLQRKMHIGYPRAARLADELREAIE
GDDGKAEVPKDEY

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=501, Percent_Identity=40.1197604790419, Blast_Score=339, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88902; Mature: 88771

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKEDPRDTLRNARPRAKSAVKVTARPFKKTAPVRSKAKKTAAKKAFSNTPVRGGASWL
CCCCCCHHHHHHCCCCCCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
WVMLIASAMAFVVWQWEGVMDFFANFGSGTAGLFGWGLLLILLGIIIAIVALRFDQMSEW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRYRLNLWNKWLGGVVLILAAWGMLGMMDAGGDIGLSILGGNADINGFMRVLALIVLGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
ILIAPGAVWRSLSGLFRGIFSPSRRSNMPEVARLDRTVVSRPVFGGDEDRIDMGEEARRP
HHHCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCC
LPEKAAPKIELPSIKLPSFGKAESRVVEVKNPLAAKSTPQTELPNMPPETAAKEPKSVDE
CCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCHHH
RTDADRKQIASEVWKKYGEAEGIAEVDGWKLPPIEMLDKTTEIGFSEADNLQRARAIEEA
HCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LASYGVEGKVIQINAGPTVTQFGVEPGWDRKFKEVKERDKDGETVSRQVEVSKTRVKVDR
HHHCCCCCEEEEEECCCCEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
IASLANDLALALAAPSLRIEAPVPGKSIVGIEVPNTSFGVVSMRSVMETNTFQKILARSP
HHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
LALALGKGAGGEAVSGDLTKMPHLLIAGATGSGKTVCLNSIICCMLLNNTPSSVKFIMID
CEEEECCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEC
PKRVELTPFNGLPHLATPVIVDVEKALSALRWLAAEMDRRYQTLAAAGSRNIEGYNKTRM
CCEEEEECCCCCCCHHCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GSDRMAFIVLIIDELADLMMAGFDEVEHILCRLAQMARAVGIHLVVATQRPSVDVITGLI
CCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHH
KANFPTRISFAVTSQVDSRTILDMVGAEKLLGRGDMLYMPTEAAKPKRLQGCYVSDAESE
HCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEECCCCCC
RLIYFWTNQKDISPSEALKVEEITAPPPAPKSKSKDPLFDEAMALISEHNNIISASFLQR
EEEEEECCCCCCCHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHH
KMHIGYPRAARLADELREAIEGDDGKAEVPKDEY
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PKKEDPRDTLRNARPRAKSAVKVTARPFKKTAPVRSKAKKTAAKKAFSNTPVRGGASWL
CCCCCHHHHHHCCCCCCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
WVMLIASAMAFVVWQWEGVMDFFANFGSGTAGLFGWGLLLILLGIIIAIVALRFDQMSEW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHRYRLNLWNKWLGGVVLILAAWGMLGMMDAGGDIGLSILGGNADINGFMRVLALIVLGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
ILIAPGAVWRSLSGLFRGIFSPSRRSNMPEVARLDRTVVSRPVFGGDEDRIDMGEEARRP
HHHCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCC
LPEKAAPKIELPSIKLPSFGKAESRVVEVKNPLAAKSTPQTELPNMPPETAAKEPKSVDE
CCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCCHHH
RTDADRKQIASEVWKKYGEAEGIAEVDGWKLPPIEMLDKTTEIGFSEADNLQRARAIEEA
HCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LASYGVEGKVIQINAGPTVTQFGVEPGWDRKFKEVKERDKDGETVSRQVEVSKTRVKVDR
HHHCCCCCEEEEEECCCCEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
IASLANDLALALAAPSLRIEAPVPGKSIVGIEVPNTSFGVVSMRSVMETNTFQKILARSP
HHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
LALALGKGAGGEAVSGDLTKMPHLLIAGATGSGKTVCLNSIICCMLLNNTPSSVKFIMID
CEEEECCCCCCCCCCCCHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEC
PKRVELTPFNGLPHLATPVIVDVEKALSALRWLAAEMDRRYQTLAAAGSRNIEGYNKTRM
CCEEEEECCCCCCCHHCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GSDRMAFIVLIIDELADLMMAGFDEVEHILCRLAQMARAVGIHLVVATQRPSVDVITGLI
CCCCCEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHH
KANFPTRISFAVTSQVDSRTILDMVGAEKLLGRGDMLYMPTEAAKPKRLQGCYVSDAESE
HCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEECCCCCC
RLIYFWTNQKDISPSEALKVEEITAPPPAPKSKSKDPLFDEAMALISEHNNIISASFLQR
EEEEEECCCCCCCHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHH
KMHIGYPRAARLADELREAIEGDDGKAEVPKDEY
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]