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The map label for this gene is atpC

Identifier: 57234666

GI number: 57234666

Start: 520082

End: 520504

Strand: Direct

Name: atpC

Synonym: DET0565

Alternate gene names: 57234666

Gene position: 520082-520504 (Clockwise)

Preceding gene: 57234667

Following gene: 57234654

Centisome position: 35.39

GC content: 54.61

Gene sequence:

>423_bases
TTGGCTAAATTAAAGCTGGACATAGTAACTGCGGAACGTTCGGTCTTTTCCGAAGAGGTGGATTTGGTGGTTGCCCCTGG
TATTGAGGGTGAAATGGCCATACTGCCTCATCATGCCCCGCTGATGACAGCTTTGCAGGCGGGGGAACTTAAGGCCAAGA
TAGGCTCTGAGGAGTATTCTATGGTGGTTTCCGGCGGTTTCCTTGAGGTGCGGCCTGACAGGGTAATTGTACTGGCGGAC
AGTGCTGAAAGGGCTGAGGAAATTGACATTGCCCGGGCTACCGAGGCTAAGAAGAGGGCTGAAGCCCGCATGGCTGACAA
ATACGAGCCCGGTATGCTGGCTGCCGAAACAGAGGCTTCGCTGAGACGGGCTATGATACGCCTTAAGGTGGCTGAGAAGC
GGCGGAAACGCCCCTCTGTTTAG

Upstream 100 bases:

>100_bases
GCCTGAACAGGCTTTCTATATGGTAGGCACTATTGATGATGCCGTAGCCGAAGCTAAAAAGCTCAGCGCGGCCTAAGTAT
TATATCTGGCAGGTAAAAAA

Downstream 100 bases:

>100_bases
TCGGAATTCAGTACTTACAATAAAAGCCCCTCTAACGAGGGGCTTTTTGTTTAAGCGGCGGAAACTAAATCTAGTCAAGC
AGTCCGGGAATAGGGTCTAT

Product: F0F1 ATP synthase subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MAKLKLDIVTAERSVFSEEVDLVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGSEEYSMVVSGGFLEVRPDRVIVLAD
SAERAEEIDIARATEAKKRAEARMADKYEPGMLAAETEASLRRAMIRLKVAEKRRKRPSV

Sequences:

>Translated_140_residues
MAKLKLDIVTAERSVFSEEVDLVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGSEEYSMVVSGGFLEVRPDRVIVLAD
SAERAEEIDIARATEAKKRAEARMADKYEPGMLAAETEASLRRAMIRLKVAEKRRKRPSV
>Mature_139_residues
AKLKLDIVTAERSVFSEEVDLVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGSEEYSMVVSGGFLEVRPDRVIVLADS
AERAEEIDIARATEAKKRAEARMADKYEPGMLAAETEASLRRAMIRLKVAEKRRKRPSV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

Organism=Escherichia coli, GI1790169, Length=133, Percent_Identity=41.3533834586466, Blast_Score=94, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_DEHE1 (Q3Z8Z1)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181308.1
- ProteinModelPortal:   Q3Z8Z1
- SMR:   Q3Z8Z1
- STRING:   Q3Z8Z1
- GeneID:   3230135
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0565
- NMPDR:   fig|243164.3.peg.423
- TIGR:   DET0565
- eggNOG:   COG0355
- HOGENOM:   HBG663981
- OMA:   ARAELME
- PhylomeDB:   Q3Z8Z1
- ProtClustDB:   PRK00571
- BioCyc:   DETH243164:DET_0565-MONOMER
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020547
- InterPro:   IPR020546
- Gene3D:   G3DSA:1.20.5.440
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF00401 ATP-synt_DE; PF02823 ATP-synt_DE_N; SSF46604 ATPsynt_DE; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 15386; Mature: 15255

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLKLDIVTAERSVFSEEVDLVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGSEEYS
CCEEEEEEEECCHHHHHCCCCEEEECCCCCCEEEECCCCHHHHHHHCCCHHHHCCCCCEE
MVVSGGFLEVRPDRVIVLADSAERAEEIDIARATEAKKRAEARMADKYEPGMLAAETEAS
EEEECCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
LRRAMIRLKVAEKRRKRPSV
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKLKLDIVTAERSVFSEEVDLVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGSEEYS
CEEEEEEEECCHHHHHCCCCEEEECCCCCCEEEECCCCHHHHHHHCCCHHHHCCCCCEE
MVVSGGFLEVRPDRVIVLADSAERAEEIDIARATEAKKRAEARMADKYEPGMLAAETEAS
EEEECCEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
LRRAMIRLKVAEKRRKRPSV
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA