Click here to switch to the map view.

The map label for this gene is atpD

Identifier: 57234667

GI number: 57234667

Start: 518663

End: 520057

Strand: Direct

Name: atpD

Synonym: DET0564

Alternate gene names: 57234667

Gene position: 518663-520057 (Clockwise)

Preceding gene: 57234627

Following gene: 57234666

Centisome position: 35.29

GC content: 51.47

Gene sequence:

>1395_bases
ATGGCAAACGGAAAGGTTATACAGGTAATTGGTTCGGTTGTTGACGTAGAGTTCTCGGCAGATTCCATGCCGGCTCTGTT
TAACGCATTGGAAATTCCCCGTGATAACGGCAAGATGGTGCTGGAAGTGCAGTCACACGTCGGTAACAACCGCGTAAAGT
GCCTTTCCTTTACTCCTACCGATGGTCTGGAGCGCGGCGCCGAGGTTATAGATACCAAAAGGCCGCTTTCAGTTCCGGTA
GGCCGGAATACTCTGGGGCGTATCTTTAACGTGCTGGGTGAACCTCTGGATAACAGGGGTGATGTAAAAGCTGAAAAGAC
TATGCCTATCCACCGCTCGGCACCAGCTATGGACGAGCTGGAATCTTCTGCTCAGGTATTGGAAACAGGTCTTAAAGTTA
TCGACCTGATTGCCCCCTTTGCCCGCGGCGGTAAGATCGGTGCTTTGGGTGGCGCTGGCGTAGGCAAGACAGTGCTTATT
CAGGAACTTATCCGCAATATTGCTACCGAACACGAAGGGTTTTCGGTTTTTGCCGGTGTAGGTGAACGTTCCCGCGAAGG
TAATGACCTCTGGCATGAAATGGAAGACTCCGGCGTGCTTCCCAAAACTACCATGGTATTCGGTCAGATGAATGAGCTTC
CCGCAGTACGTCTGCGTATTGCTCTTACCGGCCTTACCATGGCCGAATATTTCCGTGACGAAGAAAGACAGGACGTGCTC
CTGTTTATTGACAATATTTATCGTTATACTCTGGCCGGTATGGAAGTATCCGCTCTTCTGGGGCGTATGCCTTCCGCTGT
AGGTTATCAGCCTACTCTGGCTACAGAGATGGGTGCTCTGCAGGAACGCATTGCCTCCACCAAACAGGGTTCGATTACTT
CATTCCAGGCTGTGTATGTACCGGCAGATGACTATACCGATCCCGGTGTAGTCGCCACCTTCGGTCACCTGGATGCTATG
ATAGCCCTTGAGCGTTCACTGGCTGAACAGGCTCTTTATCCGGCGGTAGACCCGCTGGCTTCCAATTCCCGCATACTTGA
CCCTCAGGTAGTGGGTGAGGAACACTATCAGGTAGCCCGTGACGTGCAGAAGGTTCTCCAGCGTTACAAGGACCTGCAGG
ACGTTATTGCTATCTTGGGTATGGAAGAACTTTCTGAAGAAGATAAACTCACAGTTGCCCGTGCCCGCCGTATTCAGCGT
TTCCTGACTCAGCCCATGTTTGTTTCCGAGGTATTTACCGGCCGTCCCGGTCAGTATGTATCTCTGGCTGAGACTATCCG
CGGGTTCAAGGAAATCCTTGAGGGTAAGCATGACAGTTTGCCTGAACAGGCTTTCTATATGGTAGGCACTATTGATGATG
CCGTAGCCGAAGCTAAAAAGCTCAGCGCGGCCTAA

Upstream 100 bases:

>100_bases
GACACTTGTTTACAACAAGGCTCGTCAGGAATCTATCACTAATGAGCTTTTGGACATCGTCGGCGGAGCTGCCGCGCTGG
CCTAATTCTAGGAGGATATA

Downstream 100 bases:

>100_bases
GTATTATATCTGGCAGGTAAAAAATTGGCTAAATTAAAGCTGGACATAGTAACTGCGGAACGTTCGGTCTTTTCCGAAGA
GGTGGATTTGGTGGTTGCCC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MANGKVIQVIGSVVDVEFSADSMPALFNALEIPRDNGKMVLEVQSHVGNNRVKCLSFTPTDGLERGAEVIDTKRPLSVPV
GRNTLGRIFNVLGEPLDNRGDVKAEKTMPIHRSAPAMDELESSAQVLETGLKVIDLIAPFARGGKIGALGGAGVGKTVLI
QELIRNIATEHEGFSVFAGVGERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVL
LFIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYVPADDYTDPGVVATFGHLDAM
IALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYQVARDVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQR
FLTQPMFVSEVFTGRPGQYVSLAETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAA

Sequences:

>Translated_464_residues
MANGKVIQVIGSVVDVEFSADSMPALFNALEIPRDNGKMVLEVQSHVGNNRVKCLSFTPTDGLERGAEVIDTKRPLSVPV
GRNTLGRIFNVLGEPLDNRGDVKAEKTMPIHRSAPAMDELESSAQVLETGLKVIDLIAPFARGGKIGALGGAGVGKTVLI
QELIRNIATEHEGFSVFAGVGERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVL
LFIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYVPADDYTDPGVVATFGHLDAM
IALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYQVARDVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQR
FLTQPMFVSEVFTGRPGQYVSLAETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAA
>Mature_463_residues
ANGKVIQVIGSVVDVEFSADSMPALFNALEIPRDNGKMVLEVQSHVGNNRVKCLSFTPTDGLERGAEVIDTKRPLSVPVG
RNTLGRIFNVLGEPLDNRGDVKAEKTMPIHRSAPAMDELESSAQVLETGLKVIDLIAPFARGGKIGALGGAGVGKTVLIQ
ELIRNIATEHEGFSVFAGVGERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVLL
FIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYVPADDYTDPGVVATFGHLDAMI
ALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYQVARDVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQRF
LTQPMFVSEVFTGRPGQYVSLAETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=467, Percent_Identity=62.0985010706638, Blast_Score=602, Evalue=1e-172,
Organism=Homo sapiens, GI19913424, Length=323, Percent_Identity=28.7925696594427, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI19913428, Length=353, Percent_Identity=25.7790368271955, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI19913426, Length=348, Percent_Identity=25.2873563218391, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI50345984, Length=400, Percent_Identity=23.25, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4757810, Length=400, Percent_Identity=23.25, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790170, Length=461, Percent_Identity=66.8112798264642, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=392, Percent_Identity=28.8265306122449, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790172, Length=358, Percent_Identity=26.8156424581006, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=467, Percent_Identity=61.0278372591007, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17565854, Length=324, Percent_Identity=29.320987654321, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=375, Percent_Identity=25.0666666666667, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=350, Percent_Identity=25.1428571428571, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988080, Length=372, Percent_Identity=23.9247311827957, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988063, Length=372, Percent_Identity=23.9247311827957, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988074, Length=329, Percent_Identity=23.1003039513678, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=64.1921397379913, Blast_Score=608, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6319603, Length=385, Percent_Identity=27.7922077922078, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6319370, Length=363, Percent_Identity=24.5179063360882, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=28.3261802575107, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638766, Length=466, Percent_Identity=61.3733905579399, Blast_Score=594, Evalue=1e-170,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=59.8726114649682, Blast_Score=565, Evalue=1e-161,
Organism=Drosophila melanogaster, GI20129479, Length=321, Percent_Identity=30.2180685358255, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24583988, Length=331, Percent_Identity=27.4924471299094, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583986, Length=331, Percent_Identity=27.4924471299094, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583984, Length=331, Percent_Identity=27.4924471299094, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583992, Length=327, Percent_Identity=26.605504587156, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281361666, Length=349, Percent_Identity=25.214899713467, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646341, Length=349, Percent_Identity=25.214899713467, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136796, Length=349, Percent_Identity=25.214899713467, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=48.9130434782609, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24658560, Length=417, Percent_Identity=23.7410071942446, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_DEHE1 (Q3Z8Z2)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181307.1
- ProteinModelPortal:   Q3Z8Z2
- SMR:   Q3Z8Z2
- STRING:   Q3Z8Z2
- GeneID:   3230136
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0564
- NMPDR:   fig|243164.3.peg.422
- TIGR:   DET0564
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   Q3Z8Z2
- ProtClustDB:   PRK09280
- BioCyc:   DETH243164:DET_0564-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50740; Mature: 50608

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANGKVIQVIGSVVDVEFSADSMPALFNALEIPRDNGKMVLEVQSHVGNNRVKCLSFTPT
CCCCHHHHEEHHHHEEEECCCCHHHHHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEECCC
DGLERGAEVIDTKRPLSVPVGRNTLGRIFNVLGEPLDNRGDVKAEKTMPIHRSAPAMDEL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCHHHH
ESSAQVLETGLKVIDLIAPFARGGKIGALGGAGVGKTVLIQELIRNIATEHEGFSVFAGV
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECC
GERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVL
CCCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHH
LFIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYV
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
PADDYTDPGVVATFGHLDAMIALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYQVAR
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHCCHHHHHHHH
DVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQRFLTQPMFVSEVFTGRPGQYV
HHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCH
SLAETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAA
HHHHHHHHHHHHHCCCCCCCCHHHEEEEECHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANGKVIQVIGSVVDVEFSADSMPALFNALEIPRDNGKMVLEVQSHVGNNRVKCLSFTPT
CCCHHHHEEHHHHEEEECCCCHHHHHHHHHCCCCCCCEEEEEHHHCCCCCEEEEEECCC
DGLERGAEVIDTKRPLSVPVGRNTLGRIFNVLGEPLDNRGDVKAEKTMPIHRSAPAMDEL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCHHHH
ESSAQVLETGLKVIDLIAPFARGGKIGALGGAGVGKTVLIQELIRNIATEHEGFSVFAGV
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECC
GERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVL
CCCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHH
LFIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYV
HHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
PADDYTDPGVVATFGHLDAMIALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYQVAR
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHCCHHHHHHHH
DVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQRFLTQPMFVSEVFTGRPGQYV
HHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCH
SLAETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAA
HHHHHHHHHHHHHCCCCCCCCHHHEEEEECHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA