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The map label for this gene is lacD [H]

Identifier: 57233912

GI number: 57233912

Start: 1215887

End: 1216897

Strand: Direct

Name: lacD [H]

Synonym: DET1345

Alternate gene names: 57233912

Gene position: 1215887-1216897 (Clockwise)

Preceding gene: 57233923

Following gene: 57233911

Centisome position: 82.73

GC content: 53.81

Gene sequence:

>1011_bases
ATGACTATCAGTGCCGGTAAACTGCTTAACCTGACTGCTCTGGCCAGCCAGAGAGGTTTATTTGAGATTGCGGCTATGGA
CCACCGCGGCTCCATAAAAAAGCACCTCTGCCCGAAAACCACCGAAGAAGAATGCTACCGCAGCCTGGCTGATTTCAAAC
TGAGCCTTTGCCGGGCTTTTTCAGGGCAGGCCAGCGCCGTACTCCTTGACCCCATTTACGGGCTGCCTGAGTGCCTGGCC
CAAAACGCCATTGCACCCGGCTGCGGCTTGCTTGTCAGCCTGGAATCAAGCGGTTACTGCGGAGAGGCTGAGTACCGGAC
TACCGAACTTCTTAAAAACTGGGGGGTAAACAAGATAAAACTGCTGGGGGCAAACGCCGTCAAGCTGCTGCTTTATTACC
GCCCGGATATAAAAGATTTAGCCAAGACCCAGCAGCTTCTGGTAAAAACCGTGGCTGACGAATGCCGCAAACTGGATATC
CCCTTTGTGCTGGAGCCTGTTACCTACCCCACCGGGCAGGAACTGAAAAATGCCGGGCTTTTTGCCAAAAACAAACCGGG
TTTAGTCCTTTCCACCGTAGAAGATTTGGCAGGACTGGGTATAGATATACTCAAGGTGGAGTTTCCCGCCGACCTCCGCT
TCAGCCTGACCGAAGATGAGGCCTTTATATCCGCCCGAAAACTGGACTCCATCTGTCCCGTACCCTGGGCTATACTCTCT
GCCGGGGCGGATTTTAACCTGTACGTGCGTGAACTGGAGATAGCCTGCCAGTGCGGGGCATCCGGTTTTCTGGCCGGCAG
AGCCGTCTGGCAGGAAGCTTTGGAGATAACCAACCCGGTAAACCGCCAGGATTTTATAAACCGCGTGGCCGCCGAAAGGT
TTAAACGCCTGTGTCAGATAGCCGAAAATACGGGACGCCCCTGGCATGAAAAACTGGGACTTAAAGCGGGTAATTTTATA
AACCCCAGCCCCACCTGGTATGCCAACTACCAGCCGGGAGAAAACCCATGA

Upstream 100 bases:

>100_bases
CGCATTCCACTTTCATAGCTAAAAGCCATTATATCCCGTATATCCTGCCAAAACAAATAGTTCTTGATTTAGATGCTTTA
ATGCTACATAATGGCTTAAG

Downstream 100 bases:

>100_bases
TTACCACCGTTACCCTAAACCCCTGTCTGGACAAACACATAGACGTGCATGGTCTGGTACTGTACGAAACTAACCGCTGG
CATCTTATGTCCAAATATGC

Product: tagatose 1,6-diphosphate aldolase

Products: NA

Alternate protein names: D-tagatose-1,6-bisphosphate aldolase; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTISAGKLLNLTALASQRGLFEIAAMDHRGSIKKHLCPKTTEEECYRSLADFKLSLCRAFSGQASAVLLDPIYGLPECLA
QNAIAPGCGLLVSLESSGYCGEAEYRTTELLKNWGVNKIKLLGANAVKLLLYYRPDIKDLAKTQQLLVKTVADECRKLDI
PFVLEPVTYPTGQELKNAGLFAKNKPGLVLSTVEDLAGLGIDILKVEFPADLRFSLTEDEAFISARKLDSICPVPWAILS
AGADFNLYVRELEIACQCGASGFLAGRAVWQEALEITNPVNRQDFINRVAAERFKRLCQIAENTGRPWHEKLGLKAGNFI
NPSPTWYANYQPGENP

Sequences:

>Translated_336_residues
MTISAGKLLNLTALASQRGLFEIAAMDHRGSIKKHLCPKTTEEECYRSLADFKLSLCRAFSGQASAVLLDPIYGLPECLA
QNAIAPGCGLLVSLESSGYCGEAEYRTTELLKNWGVNKIKLLGANAVKLLLYYRPDIKDLAKTQQLLVKTVADECRKLDI
PFVLEPVTYPTGQELKNAGLFAKNKPGLVLSTVEDLAGLGIDILKVEFPADLRFSLTEDEAFISARKLDSICPVPWAILS
AGADFNLYVRELEIACQCGASGFLAGRAVWQEALEITNPVNRQDFINRVAAERFKRLCQIAENTGRPWHEKLGLKAGNFI
NPSPTWYANYQPGENP
>Mature_335_residues
TISAGKLLNLTALASQRGLFEIAAMDHRGSIKKHLCPKTTEEECYRSLADFKLSLCRAFSGQASAVLLDPIYGLPECLAQ
NAIAPGCGLLVSLESSGYCGEAEYRTTELLKNWGVNKIKLLGANAVKLLLYYRPDIKDLAKTQQLLVKTVADECRKLDIP
FVLEPVTYPTGQELKNAGLFAKNKPGLVLSTVEDLAGLGIDILKVEFPADLRFSLTEDEAFISARKLDSICPVPWAILSA
GADFNLYVRELEIACQCGASGFLAGRAVWQEALEITNPVNRQDFINRVAAERFKRLCQIAENTGRPWHEKLGLKAGNFIN
PSPTWYANYQPGENP

Specific function: Unknown

COG id: COG3684

COG function: function code G; Tagatose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase lacD family [H]

Homologues:

Organism=Escherichia coli, GI1790314, Length=253, Percent_Identity=29.2490118577075, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 36940; Mature: 36809

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISAGKLLNLTALASQRGLFEIAAMDHRGSIKKHLCPKTTEEECYRSLADFKLSLCRAF
CCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SGQASAVLLDPIYGLPECLAQNAIAPGCGLLVSLESSGYCGEAEYRTTELLKNWGVNKIK
CCCCCEEEECCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEE
LLGANAVKLLLYYRPDIKDLAKTQQLLVKTVADECRKLDIPFVLEPVTYPTGQELKNAGL
EECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHCCC
FAKNKPGLVLSTVEDLAGLGIDILKVEFPADLRFSLTEDEAFISARKLDSICPVPWAILS
CCCCCCCEEEEEHHHHHCCCEEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHH
AGADFNLYVRELEIACQCGASGFLAGRAVWQEALEITNPVNRQDFINRVAAERFKRLCQI
CCCCCEEEHHEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AENTGRPWHEKLGLKAGNFINPSPTWYANYQPGENP
HHHCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TISAGKLLNLTALASQRGLFEIAAMDHRGSIKKHLCPKTTEEECYRSLADFKLSLCRAF
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SGQASAVLLDPIYGLPECLAQNAIAPGCGLLVSLESSGYCGEAEYRTTELLKNWGVNKIK
CCCCCEEEECCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEE
LLGANAVKLLLYYRPDIKDLAKTQQLLVKTVADECRKLDIPFVLEPVTYPTGQELKNAGL
EECCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHCCC
FAKNKPGLVLSTVEDLAGLGIDILKVEFPADLRFSLTEDEAFISARKLDSICPVPWAILS
CCCCCCCEEEEEHHHHHCCCEEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHH
AGADFNLYVRELEIACQCGASGFLAGRAVWQEALEITNPVNRQDFINRVAAERFKRLCQI
CCCCCEEEHHEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
AENTGRPWHEKLGLKAGNFINPSPTWYANYQPGENP
HHHCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]