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The map label for this gene is aroF [H]

Identifier: 57233821

GI number: 57233821

Start: 1343688

End: 1344710

Strand: Direct

Name: aroF [H]

Synonym: DET1486

Alternate gene names: 57233821

Gene position: 1343688-1344710 (Clockwise)

Preceding gene: 57233822

Following gene: 57233820

Centisome position: 91.42

GC content: 50.83

Gene sequence:

>1023_bases
ATGTTAGTAATAATGAAAAACGATGCAACTCAGGAACAGATAGATAACGTCATCCGTGAGATTACGGATGCAGGCTACCG
GGGCATACCCATACCGGGTGACCACCGAACCGCCGTCTGCATAGTGGGCAATCAGGGTATGGTGGAGGAAAGCCCTTTTC
TGGCACTGGAAGGTGTGAAAGAAGTATTGCGGGTGACCAAGCCCTATAAACTGGTCAGCCATGAAACCTGCCCCAAACCG
ACAGTTATCCGTCTGGGAGAGGTAGAAATAGGAAACGGCTGCAAACCGGTTATCATTGCCGGACCTTGCTCGGTGGAAAG
TGAAGAACAGACCCTCCGCATAGCCCGTCAGGTAAAAGAGGGCGGTGCCAAGCTCTTCAGGGGAGGGGCATTCAAACCCC
GCACTTCACCCTACAGCTTTCAGGGTTTGGGCAAAGCCGGCCTCAAAATACTGGAAAAAGTACGCTCTGAAACTGGGTTG
CTTATTGTTACCGAAGCCACCGACTCTGAAAACCTGAAGCTGGTTGAAGCCAGCACAGATATTATCCAGATAGGTGCCCG
AAACATGCAAAATTACTCTCTGTTACGCAGGGCAGGCCAGACAAAAAAGCCGGTCATTTTAAAACGGGGGCTGTCAGCCA
CTATTGAAGAACTGCTGATGGCAGCCGAATATATAATAGCCGAAGGCAACACTCAAGTTATTTTGTGCGAACGGGGTATC
CGCACCTTTTCGGACAATACCCGCTTTACACTGGACCTAAGCGCCATCCTGTCCGTCAAGGCCTTAAGTCACCTGCCCAT
CATAGTAGACCCCAGCCATGCCGCCGGACGCCGTGATTATGTTATCCCCCTGTCCAGAGCAGCCATTGCAACAGGGGCAG
ACGGACTGATAGTAGAAGTCCATTCAGACCCGCCCAGCGCTCTGTCTGACGGGGCGCAGTCTTTGTATCCGGAACAGTTT
TGCCAATTGGTTAAAGAGGTGGAATATTTAAATATGCTGGGAGTAGAAAAATGCCTAAAGTAG

Upstream 100 bases:

>100_bases
GAATAGACGTTGCCAGCGGAGTGGAAACAGACGGGATAAAAGATACAGCCAAAATACACCTTTTCATTGAACGGGTGAAA
GATGCGGATGGTAACCGGAT

Downstream 100 bases:

>100_bases
ATAGCACCGGTAAACCGGGGTATTTCGGCAAGTATGGCGGGCAGTTTGTACCTGAAATACTGGTGCCAGTCCTAAACGAA
CTGGAACAGGCTTATGAACA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLVIMKNDATQEQIDNVIREITDAGYRGIPIPGDHRTAVCIVGNQGMVEESPFLALEGVKEVLRVTKPYKLVSHETCPKP
TVIRLGEVEIGNGCKPVIIAGPCSVESEEQTLRIARQVKEGGAKLFRGGAFKPRTSPYSFQGLGKAGLKILEKVRSETGL
LIVTEATDSENLKLVEASTDIIQIGARNMQNYSLLRRAGQTKKPVILKRGLSATIEELLMAAEYIIAEGNTQVILCERGI
RTFSDNTRFTLDLSAILSVKALSHLPIIVDPSHAAGRRDYVIPLSRAAIATGADGLIVEVHSDPPSALSDGAQSLYPEQF
CQLVKEVEYLNMLGVEKCLK

Sequences:

>Translated_340_residues
MLVIMKNDATQEQIDNVIREITDAGYRGIPIPGDHRTAVCIVGNQGMVEESPFLALEGVKEVLRVTKPYKLVSHETCPKP
TVIRLGEVEIGNGCKPVIIAGPCSVESEEQTLRIARQVKEGGAKLFRGGAFKPRTSPYSFQGLGKAGLKILEKVRSETGL
LIVTEATDSENLKLVEASTDIIQIGARNMQNYSLLRRAGQTKKPVILKRGLSATIEELLMAAEYIIAEGNTQVILCERGI
RTFSDNTRFTLDLSAILSVKALSHLPIIVDPSHAAGRRDYVIPLSRAAIATGADGLIVEVHSDPPSALSDGAQSLYPEQF
CQLVKEVEYLNMLGVEKCLK
>Mature_340_residues
MLVIMKNDATQEQIDNVIREITDAGYRGIPIPGDHRTAVCIVGNQGMVEESPFLALEGVKEVLRVTKPYKLVSHETCPKP
TVIRLGEVEIGNGCKPVIIAGPCSVESEEQTLRIARQVKEGGAKLFRGGAFKPRTSPYSFQGLGKAGLKILEKVRSETGL
LIVTEATDSENLKLVEASTDIIQIGARNMQNYSLLRRAGQTKKPVILKRGLSATIEELLMAAEYIIAEGNTQVILCERGI
RTFSDNTRFTLDLSAILSVKALSHLPIIVDPSHAAGRRDYVIPLSRAAIATGADGLIVEVHSDPPSALSDGAQSLYPEQF
CQLVKEVEYLNMLGVEKCLK

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=274, Percent_Identity=26.2773722627737, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36990; Mature: 36990

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVIMKNDATQEQIDNVIREITDAGYRGIPIPGDHRTAVCIVGNQGMVEESPFLALEGVK
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
EVLRVTKPYKLVSHETCPKPTVIRLGEVEIGNGCKPVIIAGPCSVESEEQTLRIARQVKE
HHHHHCCCHHHHCCCCCCCCCEEEECCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHH
GGAKLFRGGAFKPRTSPYSFQGLGKAGLKILEKVRSETGLLIVTEATDSENLKLVEASTD
CCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCC
IIQIGARNMQNYSLLRRAGQTKKPVILKRGLSATIEELLMAAEYIIAEGNTQVILCERGI
EEEECCCCCHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHEECCCCEEEEECCCC
RTFSDNTRFTLDLSAILSVKALSHLPIIVDPSHAAGRRDYVIPLSRAAIATGADGLIVEV
CCCCCCCEEEEEHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECHHHHHCCCCCEEEEE
HSDPPSALSDGAQSLYPEQFCQLVKEVEYLNMLGVEKCLK
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVIMKNDATQEQIDNVIREITDAGYRGIPIPGDHRTAVCIVGNQGMVEESPFLALEGVK
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
EVLRVTKPYKLVSHETCPKPTVIRLGEVEIGNGCKPVIIAGPCSVESEEQTLRIARQVKE
HHHHHCCCHHHHCCCCCCCCCEEEECCEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHH
GGAKLFRGGAFKPRTSPYSFQGLGKAGLKILEKVRSETGLLIVTEATDSENLKLVEASTD
CCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCC
IIQIGARNMQNYSLLRRAGQTKKPVILKRGLSATIEELLMAAEYIIAEGNTQVILCERGI
EEEECCCCCHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHEECCCCEEEEECCCC
RTFSDNTRFTLDLSAILSVKALSHLPIIVDPSHAAGRRDYVIPLSRAAIATGADGLIVEV
CCCCCCCEEEEEHHHHHHHHHHHCCCEEECCCCCCCCCCEEEEECHHHHHCCCCCEEEEE
HSDPPSALSDGAQSLYPEQFCQLVKEVEYLNMLGVEKCLK
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]