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The map label for this gene is trpB [H]

Identifier: 57233820

GI number: 57233820

Start: 1344698

End: 1345897

Strand: Direct

Name: trpB [H]

Synonym: DET1487

Alternate gene names: 57233820

Gene position: 1344698-1345897 (Clockwise)

Preceding gene: 57233821

Following gene: 57233819

Centisome position: 91.49

GC content: 52.08

Gene sequence:

>1200_bases
ATGCCTAAAGTAGATAGCACCGGTAAACCGGGGTATTTCGGCAAGTATGGCGGGCAGTTTGTACCTGAAATACTGGTGCC
AGTCCTAAACGAACTGGAACAGGCTTATGAACAAGCCAAAAAAGACGAGACTTTCCAGTCACGCCTGAAATCCCTTTCAA
ACACCTTTTCGGGGCGGCCCACTCCGCTGTATCTGGCAGAAAGGCTGACTGAACATCTGGGGGGTGCCAGAATTTACCTG
AAAAGGGAAGACCTGGCCCATACAGGTGCCCATAAAATCAACAACGCACTCGGTCAGGGGCTGCTTGCCTTGCATATGGG
AAAGAAAAGGGTAATTGCCGAAACAGGGGCGGGGCAACACGGGGTAGCCACCGCAGCTGTTTGCGCCATGCTGGGGCTGG
AATGCATTGTCTATATGGGCGAAGATGACATCAAACGTCAAGCCTTGAACGTATTCCGCATGAAGCTGATGGGAACGGAA
GTCAGAAGCGTATCTTCGGGCAGCCGTACCCTGAAAGACGCCATCAATGAAGCTATGCGTGACTGGGTAAGCAACCCGGA
GACCACTTATTATATAATCGGTTCGGTGGTCGGCCCGCGCCCTTATCCGGCTATGGTACGGGATTTTCAGGCAGTTATCG
GGCAGGAAACCAAAGCCCAGTCCTTAAGACAGCTGGGGGGACTACCTGACTGCATTGTTGCCTGTGTTGGCGGAGGCAGC
AATGCCATGGGTATTTTCTATGATTTCATACCAGACCAAAGCGTACGTCTTATCGGGGTGGAAGCTGCCGGCAGCGGCAT
CAGCACCGGCAAACATTCGGCCACCCTTAGTGCCGGCAAGGTGGGTATACTCCACGGCGCCATGTCCTACCTGCTTCAGG
ACGAGCATGGACAGGTGATTGAAACCCACAGTATTTCGGCCGGGCTGGATTATCCCGGCGTAGGACCTGAACACAGCTAC
CTGAAAGATAATAAGCGGGTGGAATATGTTTCGGTCACAGATGAAGAAGCCCTGAACGGCTTCAAACTGCTATGCTCGCT
GGAAGGGATAATGCCTGCTCTGGAATCTTCCCACGCCATTGCCCATGCCCTGAAAATAGCAGTCGGCATGCCGAAAAACA
AAAATATAGTCATAAACCTCTCCGGCAGAGGGGACAAAGACATGGATATTGTTCAAAAAGCAATGGGGGTAAAGATATGA

Upstream 100 bases:

>100_bases
CGCCCAGCGCTCTGTCTGACGGGGCGCAGTCTTTGTATCCGGAACAGTTTTGCCAATTGGTTAAAGAGGTGGAATATTTA
AATATGCTGGGAGTAGAAAA

Downstream 100 bases:

>100_bases
GCCGTATCAGTGATGCATTCCAAAAACGAAAATCTCTTATAGCTTACATAACAGTCGGCTACCCGGATATTGAAACCACC
CTGCGGCTGGTGCCTCTGCT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MPKVDSTGKPGYFGKYGGQFVPEILVPVLNELEQAYEQAKKDETFQSRLKSLSNTFSGRPTPLYLAERLTEHLGGARIYL
KREDLAHTGAHKINNALGQGLLALHMGKKRVIAETGAGQHGVATAAVCAMLGLECIVYMGEDDIKRQALNVFRMKLMGTE
VRSVSSGSRTLKDAINEAMRDWVSNPETTYYIIGSVVGPRPYPAMVRDFQAVIGQETKAQSLRQLGGLPDCIVACVGGGS
NAMGIFYDFIPDQSVRLIGVEAAGSGISTGKHSATLSAGKVGILHGAMSYLLQDEHGQVIETHSISAGLDYPGVGPEHSY
LKDNKRVEYVSVTDEEALNGFKLLCSLEGIMPALESSHAIAHALKIAVGMPKNKNIVINLSGRGDKDMDIVQKAMGVKI

Sequences:

>Translated_399_residues
MPKVDSTGKPGYFGKYGGQFVPEILVPVLNELEQAYEQAKKDETFQSRLKSLSNTFSGRPTPLYLAERLTEHLGGARIYL
KREDLAHTGAHKINNALGQGLLALHMGKKRVIAETGAGQHGVATAAVCAMLGLECIVYMGEDDIKRQALNVFRMKLMGTE
VRSVSSGSRTLKDAINEAMRDWVSNPETTYYIIGSVVGPRPYPAMVRDFQAVIGQETKAQSLRQLGGLPDCIVACVGGGS
NAMGIFYDFIPDQSVRLIGVEAAGSGISTGKHSATLSAGKVGILHGAMSYLLQDEHGQVIETHSISAGLDYPGVGPEHSY
LKDNKRVEYVSVTDEEALNGFKLLCSLEGIMPALESSHAIAHALKIAVGMPKNKNIVINLSGRGDKDMDIVQKAMGVKI
>Mature_398_residues
PKVDSTGKPGYFGKYGGQFVPEILVPVLNELEQAYEQAKKDETFQSRLKSLSNTFSGRPTPLYLAERLTEHLGGARIYLK
REDLAHTGAHKINNALGQGLLALHMGKKRVIAETGAGQHGVATAAVCAMLGLECIVYMGEDDIKRQALNVFRMKLMGTEV
RSVSSGSRTLKDAINEAMRDWVSNPETTYYIIGSVVGPRPYPAMVRDFQAVIGQETKAQSLRQLGGLPDCIVACVGGGSN
AMGIFYDFIPDQSVRLIGVEAAGSGISTGKHSATLSAGKVGILHGAMSYLLQDEHGQVIETHSISAGLDYPGVGPEHSYL
KDNKRVEYVSVTDEEALNGFKLLCSLEGIMPALESSHAIAHALKIAVGMPKNKNIVINLSGRGDKDMDIVQKAMGVKI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=388, Percent_Identity=55.6701030927835, Blast_Score=444, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321412, Length=387, Percent_Identity=57.8811369509044, Blast_Score=468, Evalue=1e-132,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42916; Mature: 42785

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVDSTGKPGYFGKYGGQFVPEILVPVLNELEQAYEQAKKDETFQSRLKSLSNTFSGRP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
TPLYLAERLTEHLGGARIYLKREDLAHTGAHKINNALGQGLLALHMGKKRVIAETGAGQH
CHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCC
GVATAAVCAMLGLECIVYMGEDDIKRQALNVFRMKLMGTEVRSVSSGSRTLKDAINEAMR
CHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DWVSNPETTYYIIGSVVGPRPYPAMVRDFQAVIGQETKAQSLRQLGGLPDCIVACVGGGS
HHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHEEECCCC
NAMGIFYDFIPDQSVRLIGVEAAGSGISTGKHSATLSAGKVGILHGAMSYLLQDEHGQVI
CCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCEE
ETHSISAGLDYPGVGPEHSYLKDNKRVEYVSVTDEEALNGFKLLCSLEGIMPALESSHAI
EECCCCCCCCCCCCCCCCHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
AHALKIAVGMPKNKNIVINLSGRGDKDMDIVQKAMGVKI
HHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PKVDSTGKPGYFGKYGGQFVPEILVPVLNELEQAYEQAKKDETFQSRLKSLSNTFSGRP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
TPLYLAERLTEHLGGARIYLKREDLAHTGAHKINNALGQGLLALHMGKKRVIAETGAGQH
CHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCC
GVATAAVCAMLGLECIVYMGEDDIKRQALNVFRMKLMGTEVRSVSSGSRTLKDAINEAMR
CHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DWVSNPETTYYIIGSVVGPRPYPAMVRDFQAVIGQETKAQSLRQLGGLPDCIVACVGGGS
HHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHEEECCCC
NAMGIFYDFIPDQSVRLIGVEAAGSGISTGKHSATLSAGKVGILHGAMSYLLQDEHGQVI
CCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCEE
ETHSISAGLDYPGVGPEHSYLKDNKRVEYVSVTDEEALNGFKLLCSLEGIMPALESSHAI
EECCCCCCCCCCCCCCCCHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
AHALKIAVGMPKNKNIVINLSGRGDKDMDIVQKAMGVKI
HHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]