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The map label for this gene is nreB [H]

Identifier: 57233701

GI number: 57233701

Start: 1406081

End: 1407115

Strand: Direct

Name: nreB [H]

Synonym: DET1560

Alternate gene names: 57233701

Gene position: 1406081-1407115 (Clockwise)

Preceding gene: 57235098

Following gene: 57233700

Centisome position: 95.67

GC content: 37.2

Gene sequence:

>1035_bases
GTGCTTGGCGAAAAACAATTACCAACGCAAGAAGTTTTGCCCGCAAATGATTTGATGATAAGCGGTATCAGAGATTCGGT
ATTTATTGCGGATCTAAATGGCAAAATAGTATTTGCTAATGATCAGGCTTGTAAAGTTCACGGATATACAAAAGGCGAAT
TTAAAGGCCTGAATGTCATAGATATAGTCCCACCCGAGCGGGTTAAAGAGGTTATGCCACACATCAACAAAGTCAAAGCA
CAGGGATATTCTATTCATAATTCAATTCACCGATGTAAAAATGGTGAAATAAAAATATCAGAGATTTCCTTAAGGCTTAT
TGAGATGGACAACCATGAATATATCCTGGCATTGTTTAAGGATATATCTGAGTTCCAAACAAAAATTCAGACTTATGTTG
CAGCACAAGAAAAAGAACGGGAGTGGGTTTCAATTGAGATTCACGACAGGATTGTCCAGAATCTGTCTGGGATTTTGCAT
CAAATAAATGCTTTGACCCTCTGCAAGAAACCTTTTAATAAGGATAAAAGAGATAAACTGGATGAATTATCGGGGCAATT
GAATAATACTATAATTGAAGCTCGAAGTATTATGCGGGAACTTTACCCAAGCACACTCGCTAGGTATGGACTTATCAGGC
TAATCCAAGAAGAATCAATTCATCTGCAAGATGAAATGCATTGTGAGATAAAGTTTAATCATTCACTGACAAAAGCAGTG
CCGCCGTATTTAGAGACAACAATATACCGGATTGTCCATGAGGCTTTATTAAATGCTAAGAAGTATTCTCAGGCATCACA
AATAGTTGTTGATCTTAATAGGACTGATAAAAATATTTCGCTTGACATATGTGATAACGGAATCGGTTTTTGCTTAAAAA
ACGTCGATTGGATACGGCCGAGTGGGTTACAAAGTATGCGCCAAAGAGCAGAGATTGTCAGCGGAACATTTTGTATTAGA
AGTGGGGTAAAGGGTACCTGTATTCATGTTTTGCTGCCTATAATTAATCACATAATGCCTACATTATCACTTTAA

Upstream 100 bases:

>100_bases
TATTTTAAGAATGAAATCCTAGACTGAGCAGTAATTAGTCTAAAATAGTCTTAGCCTAGAGCTGTATTTTGTATGTTATA
ATCCGAGTATGAGTAGAAAA

Downstream 100 bases:

>100_bases
CGATATCCGAGGTTAAAATGGGGAATTTATCAGACAATATACGTAACCCAATCAGAATATTTATTGTTGATGACCATGAA
ATAGTGAGACAAGGCCTTAA

Product: sensory box sensor histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MLGEKQLPTQEVLPANDLMISGIRDSVFIADLNGKIVFANDQACKVHGYTKGEFKGLNVIDIVPPERVKEVMPHINKVKA
QGYSIHNSIHRCKNGEIKISEISLRLIEMDNHEYILALFKDISEFQTKIQTYVAAQEKEREWVSIEIHDRIVQNLSGILH
QINALTLCKKPFNKDKRDKLDELSGQLNNTIIEARSIMRELYPSTLARYGLIRLIQEESIHLQDEMHCEIKFNHSLTKAV
PPYLETTIYRIVHEALLNAKKYSQASQIVVDLNRTDKNISLDICDNGIGFCLKNVDWIRPSGLQSMRQRAEIVSGTFCIR
SGVKGTCIHVLLPIINHIMPTLSL

Sequences:

>Translated_344_residues
MLGEKQLPTQEVLPANDLMISGIRDSVFIADLNGKIVFANDQACKVHGYTKGEFKGLNVIDIVPPERVKEVMPHINKVKA
QGYSIHNSIHRCKNGEIKISEISLRLIEMDNHEYILALFKDISEFQTKIQTYVAAQEKEREWVSIEIHDRIVQNLSGILH
QINALTLCKKPFNKDKRDKLDELSGQLNNTIIEARSIMRELYPSTLARYGLIRLIQEESIHLQDEMHCEIKFNHSLTKAV
PPYLETTIYRIVHEALLNAKKYSQASQIVVDLNRTDKNISLDICDNGIGFCLKNVDWIRPSGLQSMRQRAEIVSGTFCIR
SGVKGTCIHVLLPIINHIMPTLSL
>Mature_344_residues
MLGEKQLPTQEVLPANDLMISGIRDSVFIADLNGKIVFANDQACKVHGYTKGEFKGLNVIDIVPPERVKEVMPHINKVKA
QGYSIHNSIHRCKNGEIKISEISLRLIEMDNHEYILALFKDISEFQTKIQTYVAAQEKEREWVSIEIHDRIVQNLSGILH
QINALTLCKKPFNKDKRDKLDELSGQLNNTIIEARSIMRELYPSTLARYGLIRLIQEESIHLQDEMHCEIKFNHSLTKAV
PPYLETTIYRIVHEALLNAKKYSQASQIVVDLNRTDKNISLDICDNGIGFCLKNVDWIRPSGLQSMRQRAEIVSGTFCIR
SGVKGTCIHVLLPIINHIMPTLSL

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=189, Percent_Identity=26.984126984127, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39162; Mature: 39162

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGEKQLPTQEVLPANDLMISGIRDSVFIADLNGKIVFANDQACKVHGYTKGEFKGLNVI
CCCCCCCCHHHCCCCCCCEEECCCCEEEEEECCCEEEEECCCEEEEECCCCCCCCCCEEE
DIVPPERVKEVMPHINKVKAQGYSIHNSIHRCKNGEIKISEISLRLIEMDNHEYILALFK
ECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCHHHHHHHH
DISEFQTKIQTYVAAQEKEREWVSIEIHDRIVQNLSGILHQINALTLCKKPFNKDKRDKL
HHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DELSGQLNNTIIEARSIMRELYPSTLARYGLIRLIQEESIHLQDEMHCEIKFNHSLTKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHC
PPYLETTIYRIVHEALLNAKKYSQASQIVVDLNRTDKNISLDICDNGIGFCLKNVDWIRP
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCHHHHHCCCCCCCC
SGLQSMRQRAEIVSGTFCIRSGVKGTCIHVLLPIINHIMPTLSL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLGEKQLPTQEVLPANDLMISGIRDSVFIADLNGKIVFANDQACKVHGYTKGEFKGLNVI
CCCCCCCCHHHCCCCCCCEEECCCCEEEEEECCCEEEEECCCEEEEECCCCCCCCCCEEE
DIVPPERVKEVMPHINKVKAQGYSIHNSIHRCKNGEIKISEISLRLIEMDNHEYILALFK
ECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCCHHHHHHHH
DISEFQTKIQTYVAAQEKEREWVSIEIHDRIVQNLSGILHQINALTLCKKPFNKDKRDKL
HHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DELSGQLNNTIIEARSIMRELYPSTLARYGLIRLIQEESIHLQDEMHCEIKFNHSLTKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHC
PPYLETTIYRIVHEALLNAKKYSQASQIVVDLNRTDKNISLDICDNGIGFCLKNVDWIRP
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCHHHHHCCCCCCCC
SGLQSMRQRAEIVSGTFCIRSGVKGTCIHVLLPIINHIMPTLSL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]