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The map label for this gene is degU [H]

Identifier: 57233700

GI number: 57233700

Start: 1407133

End: 1407813

Strand: Direct

Name: degU [H]

Synonym: DET1561

Alternate gene names: 57233700

Gene position: 1407133-1407813 (Clockwise)

Preceding gene: 57233701

Following gene: 57233699

Centisome position: 95.74

GC content: 35.68

Gene sequence:

>681_bases
ATGGGGAATTTATCAGACAATATACGTAACCCAATCAGAATATTTATTGTTGATGACCATGAAATAGTGAGACAAGGCCT
TAAAGTCATTATTAATCAAGAACAGGACTTTGAATTAGTAGGTGAATCAAATGGACAAAAAGGACTCCTGAAGGAAATTG
CTGAAGCTCATCCGGATGTATTATTACTGGACATAAGGATTAGTGGTTCAGATGGATTTGATATTGCTTCACAGCTTAAT
GAAAAGTTTCCTTCCATAAAAATTCTGATAATTTCCGGATATGAAAGTGAATTGTATTTAGTTGAGGCATTAGATCATAA
GGTTAGCGGATTTATACCGAAGGGGTCTTCGCGAGATTATGTTTGTTCAGCGATTCGCATGGTTGCTCTTGGTGGTACAG
TTTGGCACGGAGAGCTATTGTACAGAGTTATCAGGGGGTTGAGTAGACTAGGGAATGAACCTAATGATACAAAAGTACAA
ATAGGGAAAAGCCATTTAAAACCTCGCGAATTAAAAGTACTATCATTATTGGCCAAAGGGAAGTTAAACAAAGAAATATG
CTTCGAACTACAGATATCGATGGATACTGTTAAAAAAGATATACATCAGTTAAAAAGTAAATACGGAGTGTTTAATCGTA
CTCAACTTGCTACTATAGCAACTGAGATGCAATTAAAGTAA

Upstream 100 bases:

>100_bases
GTATTAGAAGTGGGGTAAAGGGTACCTGTATTCATGTTTTGCTGCCTATAATTAATCACATAATGCCTACATTATCACTT
TAACGATATCCGAGGTTAAA

Downstream 100 bases:

>100_bases
GTGACTTATCATCAGCAAATATAAATTATTGAGGTCAATTTTATTGGGAGCATAGGGCTCAAACAGCACCCAATTTATGA
CGTCTTTAACTAATTAGAAA

Product: LuxR family DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGNLSDNIRNPIRIFIVDDHEIVRQGLKVIINQEQDFELVGESNGQKGLLKEIAEAHPDVLLLDIRISGSDGFDIASQLN
EKFPSIKILIISGYESELYLVEALDHKVSGFIPKGSSRDYVCSAIRMVALGGTVWHGELLYRVIRGLSRLGNEPNDTKVQ
IGKSHLKPRELKVLSLLAKGKLNKEICFELQISMDTVKKDIHQLKSKYGVFNRTQLATIATEMQLK

Sequences:

>Translated_226_residues
MGNLSDNIRNPIRIFIVDDHEIVRQGLKVIINQEQDFELVGESNGQKGLLKEIAEAHPDVLLLDIRISGSDGFDIASQLN
EKFPSIKILIISGYESELYLVEALDHKVSGFIPKGSSRDYVCSAIRMVALGGTVWHGELLYRVIRGLSRLGNEPNDTKVQ
IGKSHLKPRELKVLSLLAKGKLNKEICFELQISMDTVKKDIHQLKSKYGVFNRTQLATIATEMQLK
>Mature_225_residues
GNLSDNIRNPIRIFIVDDHEIVRQGLKVIINQEQDFELVGESNGQKGLLKEIAEAHPDVLLLDIRISGSDGFDIASQLNE
KFPSIKILIISGYESELYLVEALDHKVSGFIPKGSSRDYVCSAIRMVALGGTVWHGELLYRVIRGLSRLGNEPNDTKVQI
GKSHLKPRELKVLSLLAKGKLNKEICFELQISMDTVKKDIHQLKSKYGVFNRTQLATIATEMQLK

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=210, Percent_Identity=30, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=25.3588516746411, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786747, Length=215, Percent_Identity=23.2558139534884, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790102, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787473, Length=211, Percent_Identity=31.7535545023697, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788546, Length=219, Percent_Identity=25.1141552511416, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25337; Mature: 25206

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNLSDNIRNPIRIFIVDDHEIVRQGLKVIINQEQDFELVGESNGQKGLLKEIAEAHPDV
CCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCE
LLLDIRISGSDGFDIASQLNEKFPSIKILIISGYESELYLVEALDHKVSGFIPKGSSRDY
EEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEEHHHHHHCCCCCCCCCHH
VCSAIRMVALGGTVWHGELLYRVIRGLSRLGNEPNDTKVQIGKSHLKPRELKVLSLLAKG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHCCHHHHHHHHHHHHC
KLNKEICFELQISMDTVKKDIHQLKSKYGVFNRTQLATIATEMQLK
CCCCEEEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
GNLSDNIRNPIRIFIVDDHEIVRQGLKVIINQEQDFELVGESNGQKGLLKEIAEAHPDV
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCE
LLLDIRISGSDGFDIASQLNEKFPSIKILIISGYESELYLVEALDHKVSGFIPKGSSRDY
EEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEEHHHHHHCCCCCCCCCHH
VCSAIRMVALGGTVWHGELLYRVIRGLSRLGNEPNDTKVQIGKSHLKPRELKVLSLLAKG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHCCHHHHHHHHHHHHC
KLNKEICFELQISMDTVKKDIHQLKSKYGVFNRTQLATIATEMQLK
CCCCEEEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]