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The map label for this gene is nadD

Identifier: 57233677

GI number: 57233677

Start: 3186

End: 3800

Strand: Direct

Name: nadD

Synonym: DET0003

Alternate gene names: 57233677

Gene position: 3186-3800 (Clockwise)

Preceding gene: 57233686

Following gene: 57233674

Centisome position: 0.22

GC content: 50.41

Gene sequence:

>615_bases
ATGGTATCTTTAAAAACAGGCATACTGGGGGGGACTTTTGACCCTATTCATACCGGCCACCTGATACTGGCAGAAGAGGT
AAAAAAGAGGCTGGGGCTGGATGAGATTATTTTTATACCCACCGGCCAGCCATATTACAAAGCGGACAAGACTATCAGCC
CGGCTGCAGACCGCCTGAACATGGTTAAACTGGCTATATCCGGCAAGCCCTATTTCAGGGTTATGGATATTGAAATAAAA
AGAAGCGGCCCTACCTATACGGCAGACACCTTAAATGACCTGAAGCTTATTCTGCCCGAAAAGACCGAACTTTACTTTAT
ATTGGGCTGGGATAATCTGGAGGCTTTGCCGCGCTGGCATAAGGCTTCGGAAATAATACGGCTCTGCCAGCTGGTGGCGG
TGCCCCGGATAGGGCAGGCAAAGCCTGATGTGGACGAACTGGATGACAAACTGCCCGGTTTGCAGCAGAGCCTTATTATG
CTGTCCAAGCCGGAGGTAGATGTCTCTTCGTCTCTGGTAAGGGAAAGGCTGGAAAACGGACAGGGCGTGGAACATCTGGT
GCCTGAGGCAGTGGCTGCCTACATCAAAGAGCACGGTTTGTACCACAGGCAATAA

Upstream 100 bases:

>100_bases
GGCGGCAGATAATGGTGCTTCTTAAACACCGGAATGTCCAGCAGGCGTTGATAAAGGCCGGGGCAGTTATCGGCCAGAAG
ATTATAACCGGCAGGCTGGA

Downstream 100 bases:

>100_bases
AGCCGCTATTTTAACGTCAGACAAAAATAAGGGGCGTCTTAAGACGCCCCTTAGCTGTTTTCAAAGGCTTTATTTCAGCC
TTAGATATCCAGATTCTTAA

Product: nicotinate (nicotinamide) nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MVSLKTGILGGTFDPIHTGHLILAEEVKKRLGLDEIIFIPTGQPYYKADKTISPAADRLNMVKLAISGKPYFRVMDIEIK
RSGPTYTADTLNDLKLILPEKTELYFILGWDNLEALPRWHKASEIIRLCQLVAVPRIGQAKPDVDELDDKLPGLQQSLIM
LSKPEVDVSSSLVRERLENGQGVEHLVPEAVAAYIKEHGLYHRQ

Sequences:

>Translated_204_residues
MVSLKTGILGGTFDPIHTGHLILAEEVKKRLGLDEIIFIPTGQPYYKADKTISPAADRLNMVKLAISGKPYFRVMDIEIK
RSGPTYTADTLNDLKLILPEKTELYFILGWDNLEALPRWHKASEIIRLCQLVAVPRIGQAKPDVDELDDKLPGLQQSLIM
LSKPEVDVSSSLVRERLENGQGVEHLVPEAVAAYIKEHGLYHRQ
>Mature_204_residues
MVSLKTGILGGTFDPIHTGHLILAEEVKKRLGLDEIIFIPTGQPYYKADKTISPAADRLNMVKLAISGKPYFRVMDIEIK
RSGPTYTADTLNDLKLILPEKTELYFILGWDNLEALPRWHKASEIIRLCQLVAVPRIGQAKPDVDELDDKLPGLQQSLIM
LSKPEVDVSSSLVRERLENGQGVEHLVPEAVAAYIKEHGLYHRQ

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=214, Percent_Identity=33.6448598130841, Blast_Score=120, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_DEHE1 (Q3ZAJ1)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_180758.1
- HSSP:   Q9HX21
- ProteinModelPortal:   Q3ZAJ1
- SMR:   Q3ZAJ1
- STRING:   Q3ZAJ1
- GeneID:   3229140
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0003
- NMPDR:   fig|243164.3.peg.15
- TIGR:   DET0003
- eggNOG:   COG1057
- HOGENOM:   HBG739448
- OMA:   LLGWDAF
- PhylomeDB:   Q3ZAJ1
- ProtClustDB:   CLSK836841
- BioCyc:   DETH243164:DET_0003-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR019450
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2; PF10362 DUF2432

EC number: =2.7.7.18

Molecular weight: Translated: 22877; Mature: 22877

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKTGILGGTFDPIHTGHLILAEEVKKRLGLDEIIFIPTGQPYYKADKTISPAADRLN
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHE
MVKLAISGKPYFRVMDIEIKRSGPTYTADTLNDLKLILPEKTELYFILGWDNLEALPRWH
EEEEEECCCCEEEEEEEEEECCCCCEECCCCCCEEEEECCCCCEEEEEECCCHHHCCCHH
KASEIIRLCQLVAVPRIGQAKPDVDELDDKLPGLQQSLIMLSKPEVDVSSSLVRERLENG
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCC
QGVEHLVPEAVAAYIKEHGLYHRQ
CCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVSLKTGILGGTFDPIHTGHLILAEEVKKRLGLDEIIFIPTGQPYYKADKTISPAADRLN
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHE
MVKLAISGKPYFRVMDIEIKRSGPTYTADTLNDLKLILPEKTELYFILGWDNLEALPRWH
EEEEEECCCCEEEEEEEEEECCCCCEECCCCCCEEEEECCCCCEEEEEECCCHHHCCCHH
KASEIIRLCQLVAVPRIGQAKPDVDELDDKLPGLQQSLIMLSKPEVDVSSSLVRERLENG
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHCC
QGVEHLVPEAVAAYIKEHGLYHRQ
CCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA