Click here to switch to the map view.

The map label for this gene is yvrG [H]

Identifier: 56965404

GI number: 56965404

Start: 3795020

End: 3796138

Strand: Direct

Name: yvrG [H]

Synonym: ABC3642

Alternate gene names: 56965404

Gene position: 3795020-3796138 (Clockwise)

Preceding gene: 56965403

Following gene: 56965405

Centisome position: 88.18

GC content: 41.82

Gene sequence:

>1119_bases
ATGGGAATAAAAACGCGCTTCACCCTTCATTTCGCTTTGGGGCTTACCCTTTGGCTGCTAGGGACTGGGCTTAGTCTAGT
GATTCTCTTTGAAGTCCTTCTTCCCTTATTCGATGTGGTGGTTGGTGAAAATACGGAAGGACTACTAGTTGGATCGATTT
TTGCACTAAGCACTCTTGTTTGTATTGGCCTCTTTGGCTGGTATTTTGGCGGGCCGATTGCTTTTATCATGAGATGGATC
CATCAGCTCTCGCAAGGGAATTACAAGCAGCCTCCAGGCCTACGGAAGATTTACACGCGAAAAGAAACATTGCGGATGCG
TTATCTTCTTTATAAGGAAGTGCTCCATTCCCTTCAATTATTGGCTGAGCAATTACAAGCAAATGAAGTAGAAAGGAAAA
AAATCGAACAAGCAAAACAGGAATGGATAGCAGGTATTTCCCATGATTTGAAAACGCCTTTAACATATATCACAGGATAT
TCTACCCTTTTATTAACGAATCAGTATGAATGGTCAACAGAGGAAGCCCGCTCTTTTACTCAGGAGATTTATGATAAGGG
CAAACATATGGAAGAGTTAATTCAAGATTTGAATCTTGTCTTAAAATTGAATGATGGCGTTCACCTGTTCCCTATCAACA
CGACGAGCCAGGATTTGGTTGAATTTACGAAAAGGGTCGTTGCCGATATTAGCAATAGCCCACAAGCTGTTGACTATCGC
CTCCATTTTAAAACGAACAAGCCAAGAATCGACGTCGACTTTGACGACAAATTTATGCAACGCATTTTGCAAAACATTTT
AATGAATTCGATCATCCATAATCCCGAACCCGTTGACATCTATATAGAGCTTTTCGATTACAACGAACAGGCAAGAATCC
ATATAACAGATAACGGCATAGGCATGCCGACTCATATGATGGAAAATCTTTTTCAACAATACTATCGGGGGGCCACGACA
GATTCAGCCTCTGAGGGAACTGGGCTTGGTATGGCTATTGTCTATAACCTTGTTCGTGCTCATCATGGGACAATCTCTGT
AGAAAGCGAACCATCTAAAGGGACATCGTTTGATATTCACTTCCCGAAAAAAGGACGCCCTCAAGACAATATGTCTTGA

Upstream 100 bases:

>100_bases
AGCTGCGAAAGAAACTTGGCGATGATACGCGCAAACCAAAAATCATTGTCAACCTTCGGGGAATTGGCTATAAATTTATC
CCTCCAAATGAGGGCTTGCC

Downstream 100 bases:

>100_bases
GGCGTCCTTTTCATGATCGAGCCTTTCGGCTGGCTCGCGCCACACGTTCACAGGCCCCTACTGAAATTCCTCTGGCAAAA
CAATTTATAGTAAAATGGAG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MGIKTRFTLHFALGLTLWLLGTGLSLVILFEVLLPLFDVVVGENTEGLLVGSIFALSTLVCIGLFGWYFGGPIAFIMRWI
HQLSQGNYKQPPGLRKIYTRKETLRMRYLLYKEVLHSLQLLAEQLQANEVERKKIEQAKQEWIAGISHDLKTPLTYITGY
STLLLTNQYEWSTEEARSFTQEIYDKGKHMEELIQDLNLVLKLNDGVHLFPINTTSQDLVEFTKRVVADISNSPQAVDYR
LHFKTNKPRIDVDFDDKFMQRILQNILMNSIIHNPEPVDIYIELFDYNEQARIHITDNGIGMPTHMMENLFQQYYRGATT
DSASEGTGLGMAIVYNLVRAHHGTISVESEPSKGTSFDIHFPKKGRPQDNMS

Sequences:

>Translated_372_residues
MGIKTRFTLHFALGLTLWLLGTGLSLVILFEVLLPLFDVVVGENTEGLLVGSIFALSTLVCIGLFGWYFGGPIAFIMRWI
HQLSQGNYKQPPGLRKIYTRKETLRMRYLLYKEVLHSLQLLAEQLQANEVERKKIEQAKQEWIAGISHDLKTPLTYITGY
STLLLTNQYEWSTEEARSFTQEIYDKGKHMEELIQDLNLVLKLNDGVHLFPINTTSQDLVEFTKRVVADISNSPQAVDYR
LHFKTNKPRIDVDFDDKFMQRILQNILMNSIIHNPEPVDIYIELFDYNEQARIHITDNGIGMPTHMMENLFQQYYRGATT
DSASEGTGLGMAIVYNLVRAHHGTISVESEPSKGTSFDIHFPKKGRPQDNMS
>Mature_371_residues
GIKTRFTLHFALGLTLWLLGTGLSLVILFEVLLPLFDVVVGENTEGLLVGSIFALSTLVCIGLFGWYFGGPIAFIMRWIH
QLSQGNYKQPPGLRKIYTRKETLRMRYLLYKEVLHSLQLLAEQLQANEVERKKIEQAKQEWIAGISHDLKTPLTYITGYS
TLLLTNQYEWSTEEARSFTQEIYDKGKHMEELIQDLNLVLKLNDGVHLFPINTTSQDLVEFTKRVVADISNSPQAVDYRL
HFKTNKPRIDVDFDDKFMQRILQNILMNSIIHNPEPVDIYIELFDYNEQARIHITDNGIGMPTHMMENLFQQYYRGATTD
SASEGTGLGMAIVYNLVRAHHGTISVESEPSKGTSFDIHFPKKGRPQDNMS

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=284, Percent_Identity=26.056338028169, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=257, Percent_Identity=25.2918287937743, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789149, Length=347, Percent_Identity=25.6484149855908, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=24.4635193133047, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=23.8095238095238, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=270, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI48994928, Length=261, Percent_Identity=27.2030651340996, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=26.8398268398268, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=239, Percent_Identity=22.1757322175732, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=26.5822784810127, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=27.9352226720648, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=24, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42604; Mature: 42472

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKTRFTLHFALGLTLWLLGTGLSLVILFEVLLPLFDVVVGENTEGLLVGSIFALSTLV
CCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
CIGLFGWYFGGPIAFIMRWIHQLSQGNYKQPPGLRKIYTRKETLRMRYLLYKEVLHSLQL
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEQLQANEVERKKIEQAKQEWIAGISHDLKTPLTYITGYSTLLLTNQYEWSTEEARSFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCHHHHHHHH
QEIYDKGKHMEELIQDLNLVLKLNDGVHLFPINTTSQDLVEFTKRVVADISNSPQAVDYR
HHHHHCCHHHHHHHHHHHEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEE
LHFKTNKPRIDVDFDDKFMQRILQNILMNSIIHNPEPVDIYIELFDYNEQARIHITDNGI
EEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCC
GMPTHMMENLFQQYYRGATTDSASEGTGLGMAIVYNLVRAHHGTISVESEPSKGTSFDIH
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEE
FPKKGRPQDNMS
CCCCCCCCCCCC
>Mature Secondary Structure 
GIKTRFTLHFALGLTLWLLGTGLSLVILFEVLLPLFDVVVGENTEGLLVGSIFALSTLV
CCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
CIGLFGWYFGGPIAFIMRWIHQLSQGNYKQPPGLRKIYTRKETLRMRYLLYKEVLHSLQL
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEQLQANEVERKKIEQAKQEWIAGISHDLKTPLTYITGYSTLLLTNQYEWSTEEARSFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCHHHHHHHH
QEIYDKGKHMEELIQDLNLVLKLNDGVHLFPINTTSQDLVEFTKRVVADISNSPQAVDYR
HHHHHCCHHHHHHHHHHHEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEE
LHFKTNKPRIDVDFDDKFMQRILQNILMNSIIHNPEPVDIYIELFDYNEQARIHITDNGI
EEEECCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCC
GMPTHMMENLFQQYYRGATTDSASEGTGLGMAIVYNLVRAHHGTISVESEPSKGTSFDIH
CCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEE
FPKKGRPQDNMS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]