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The map label for this gene is yvrH [H]

Identifier: 56965403

GI number: 56965403

Start: 3794313

End: 3795029

Strand: Direct

Name: yvrH [H]

Synonym: ABC3641

Alternate gene names: 56965403

Gene position: 3794313-3795029 (Clockwise)

Preceding gene: 56965399

Following gene: 56965404

Centisome position: 88.16

GC content: 39.61

Gene sequence:

>717_bases
GTGGAACACGCAAAAATTTTAATAGTCGATGATGAAATAGGCATCGTAAAGCTACTGGAGATTACACTTGAAAAAGAAAA
TTTTATTCATATAGACAAAGCAACAACGGGGAAAGAGGCGCTGCAATTAACGAAAGAAAAAACATTCAACCTCATTTTGC
TTGATATCATGCTTCCAGATATTAGCGGATTTGAATTATGTACAGAAATACGACGAAATACGGATACGCCCATTATTTTT
GTTAGTTCCCGGGCTACAGACTTTGATAAATTAACGGGATTAGGGATCGGCGGAGATGATTATATTACAAAGCCTTTCAA
CCCTTTAGAAGTCATTGCCCGCATCAAGGCCATTCTTCGGCGCCAAAAAATGTATGAACGTTCAGAGAAGAAGCCGGTAT
ACGATTACGGCTACTTCGCGTTTTATCCGGAATCAGCGATATTAATGGTTCAAAATCAAACAGTAGAATGCACGGCAAAA
GAGCTGGAGTTGCTGCATTTTTTTTGTGAAAATCCTAATCGTATTTTCACTACAGCCCAGCTTTATGAACGCGTTTGGGG
AAATGATGTGTTTGGAGAAGAAAAAACAGTGACCATCCATATATCCAAGCTGCGAAAGAAACTTGGCGATGATACGCGCA
AACCAAAAATCATTGTCAACCTTCGGGGAATTGGCTATAAATTTATCCCTCCAAATGAGGGCTTGCCATGGGAATAA

Upstream 100 bases:

>100_bases
TACACACTTAGCTTAATCCATGAAAGTAAAATCAAAGTAAACAGGAAGGAAAATGCCTGTAATTTTTTCAGGATTGGGAT
TGAAATGAGGGATTATAAAA

Downstream 100 bases:

>100_bases
AAACGCGCTTCACCCTTCATTTCGCTTTGGGGCTTACCCTTTGGCTGCTAGGGACTGGGCTTAGTCTAGTGATTCTCTTT
GAAGTCCTTCTTCCCTTATT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEHAKILIVDDEIGIVKLLEITLEKENFIHIDKATTGKEALQLTKEKTFNLILLDIMLPDISGFELCTEIRRNTDTPIIF
VSSRATDFDKLTGLGIGGDDYITKPFNPLEVIARIKAILRRQKMYERSEKKPVYDYGYFAFYPESAILMVQNQTVECTAK
ELELLHFFCENPNRIFTTAQLYERVWGNDVFGEEKTVTIHISKLRKKLGDDTRKPKIIVNLRGIGYKFIPPNEGLPWE

Sequences:

>Translated_238_residues
MEHAKILIVDDEIGIVKLLEITLEKENFIHIDKATTGKEALQLTKEKTFNLILLDIMLPDISGFELCTEIRRNTDTPIIF
VSSRATDFDKLTGLGIGGDDYITKPFNPLEVIARIKAILRRQKMYERSEKKPVYDYGYFAFYPESAILMVQNQTVECTAK
ELELLHFFCENPNRIFTTAQLYERVWGNDVFGEEKTVTIHISKLRKKLGDDTRKPKIIVNLRGIGYKFIPPNEGLPWE
>Mature_238_residues
MEHAKILIVDDEIGIVKLLEITLEKENFIHIDKATTGKEALQLTKEKTFNLILLDIMLPDISGFELCTEIRRNTDTPIIF
VSSRATDFDKLTGLGIGGDDYITKPFNPLEVIARIKAILRRQKMYERSEKKPVYDYGYFAFYPESAILMVQNQTVECTAK
ELELLHFFCENPNRIFTTAQLYERVWGNDVFGEEKTVTIHISKLRKKLGDDTRKPKIIVNLRGIGYKFIPPNEGLPWE

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.0869565217391, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=31.3304721030043, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.6244541484716, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=33.1877729257642, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=31.7596566523605, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=29.9107142857143, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=31.8777292576419, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=28.3185840707965, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=29.2576419213974, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=28.2608695652174, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=30.4347826086957, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=26.5486725663717, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=26.6094420600858, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789149, Length=121, Percent_Identity=32.2314049586777, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27460; Mature: 27460

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHAKILIVDDEIGIVKLLEITLEKENFIHIDKATTGKEALQLTKEKTFNLILLDIMLPD
CCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCC
ISGFELCTEIRRNTDTPIIFVSSRATDFDKLTGLGIGGDDYITKPFNPLEVIARIKAILR
CCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RQKMYERSEKKPVYDYGYFAFYPESAILMVQNQTVECTAKELELLHFFCENPNRIFTTAQ
HHHHHHHHCCCCCEECCEEEEECCCEEEEEECCCEEHHHHHHHHHHHHHCCCCEEEEHHH
LYERVWGNDVFGEEKTVTIHISKLRKKLGDDTRKPKIIVNLRGIGYKFIPPNEGLPWE
HHHHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCCCCCC
>Mature Secondary Structure
MEHAKILIVDDEIGIVKLLEITLEKENFIHIDKATTGKEALQLTKEKTFNLILLDIMLPD
CCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCC
ISGFELCTEIRRNTDTPIIFVSSRATDFDKLTGLGIGGDDYITKPFNPLEVIARIKAILR
CCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RQKMYERSEKKPVYDYGYFAFYPESAILMVQNQTVECTAKELELLHFFCENPNRIFTTAQ
HHHHHHHHCCCCCEECCEEEEECCCEEEEEECCCEEHHHHHHHHHHHHHCCCCEEEEHHH
LYERVWGNDVFGEEKTVTIHISKLRKKLGDDTRKPKIIVNLRGIGYKFIPPNEGLPWE
HHHHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]