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The map label for this gene is rbsK [H]

Identifier: 56965405

GI number: 56965405

Start: 3796264

End: 3797142

Strand: Direct

Name: rbsK [H]

Synonym: ABC3643

Alternate gene names: 56965405

Gene position: 3796264-3797142 (Clockwise)

Preceding gene: 56965404

Following gene: 56965407

Centisome position: 88.21

GC content: 50.4

Gene sequence:

>879_bases
TTGATTACGGTTGTTGGCAGTATAAACATTGATCTTGTCGTCCATACGGGCACCATGCCTGTCTTAGGGGAAACAGTGCT
TGGCGGCGAGTTTCAAACGAATCCAGGAGGAAAAGGGGCCAATCAAGCAGTTGCTGCGGCAAGGCTTGGTGCTGACGTGA
CGATGATAGGCAAAGTCGGCAATGACCCGTACGGAAAGCTTGTCACAGACAACTTACAAAACGAACAAATTAACACAGAT
TACATAGAGGTTGAGAAGGACGGACATACAGGCGTAGCCATGATTACGGTCACAAACAACGACAATGCGATTGTTGTCGC
GCCCGGCGCCAATTTCAGTTGGAAGCCCGAGGAGGCCGCCCAATACCGTGATGTGTTCAAACAGACAAACGTCCTCGTGC
TTCAACTTGAAGTGCCGCTCCCTTTTATCGAGGAAATCGCTAAAATAGGCAAGGAAGAACGATGCATCGTCATTCTAAAT
CCTGCCCCCGCACAGCCGTTGCCGTCATCGTTGCTTGATCTCGTTGATTATATCACTCCAAATGAAACAGAGTGCCAGAC
GATTTTTAAGCAATCGGTTGAACAAGCGGTCCAGAGATATCCAAACAAGCTGCTTGTAACAGAAGGAAAAAAAGGCGCCG
CCTACCACGACGGCCAACAGCTTGTTCAAGTGAACGGATTCCCAGCAAACGTCGTCGATACCACCGGAGCAGGCGATACA
TTCAATGGCGCCCTTGCCGCAGCTTTGGCGTCTGGCCAGCAATTAGCCGAAGCCGTGACATTTGCTAATGCTGCTGCTTC
GCTATCCGTAGAACAGGCAGGCGCACAGGCAGGGATGCCGTCAAAACAACAAGTATTGGCCCGTCTAGGCTCATCATAA

Upstream 100 bases:

>100_bases
TCGGCTGGCTCGCGCCACACGTTCACAGGCCCCTACTGAAATTCCTCTGGCAAAACAATTTATAGTAAAATGGAGTCATT
CGGAAGAGGAGGCGTATCCA

Downstream 100 bases:

>100_bases
ACAAGAGGCTCTTTCCTAAAGGGAAGGGCCTCCAGTCGTCGTTTCCGAGGGGCTTTGAAGCATATGAAGCTGTGGACGAC
TCGCCAATCATACAGCAACA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MITVVGSINIDLVVHTGTMPVLGETVLGGEFQTNPGGKGANQAVAAARLGADVTMIGKVGNDPYGKLVTDNLQNEQINTD
YIEVEKDGHTGVAMITVTNNDNAIVVAPGANFSWKPEEAAQYRDVFKQTNVLVLQLEVPLPFIEEIAKIGKEERCIVILN
PAPAQPLPSSLLDLVDYITPNETECQTIFKQSVEQAVQRYPNKLLVTEGKKGAAYHDGQQLVQVNGFPANVVDTTGAGDT
FNGALAAALASGQQLAEAVTFANAAASLSVEQAGAQAGMPSKQQVLARLGSS

Sequences:

>Translated_292_residues
MITVVGSINIDLVVHTGTMPVLGETVLGGEFQTNPGGKGANQAVAAARLGADVTMIGKVGNDPYGKLVTDNLQNEQINTD
YIEVEKDGHTGVAMITVTNNDNAIVVAPGANFSWKPEEAAQYRDVFKQTNVLVLQLEVPLPFIEEIAKIGKEERCIVILN
PAPAQPLPSSLLDLVDYITPNETECQTIFKQSVEQAVQRYPNKLLVTEGKKGAAYHDGQQLVQVNGFPANVVDTTGAGDT
FNGALAAALASGQQLAEAVTFANAAASLSVEQAGAQAGMPSKQQVLARLGSS
>Mature_292_residues
MITVVGSINIDLVVHTGTMPVLGETVLGGEFQTNPGGKGANQAVAAARLGADVTMIGKVGNDPYGKLVTDNLQNEQINTD
YIEVEKDGHTGVAMITVTNNDNAIVVAPGANFSWKPEEAAQYRDVFKQTNVLVLQLEVPLPFIEEIAKIGKEERCIVILN
PAPAQPLPSSLLDLVDYITPNETECQTIFKQSVEQAVQRYPNKLLVTEGKKGAAYHDGQQLVQVNGFPANVVDTTGAGDT
FNGALAAALASGQQLAEAVTFANAAASLSVEQAGAQAGMPSKQQVLARLGSS

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=301, Percent_Identity=34.21926910299, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=40.4682274247492, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI87082343, Length=294, Percent_Identity=27.2108843537415, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081971, Length=271, Percent_Identity=25.4612546125461, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788417, Length=305, Percent_Identity=25.2459016393443, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=290, Percent_Identity=35.5172413793103, Blast_Score=138, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=30.8157099697885, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=35.3333333333333, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24583886, Length=319, Percent_Identity=26.6457680250784, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30712; Mature: 30712

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVVGSINIDLVVHTGTMPVLGETVLGGEFQTNPGGKGANQAVAAARLGADVTMIGKVG
CEEEEEECEEEEEEECCCCCHHCHHEECCEEECCCCCCCCHHHHHHHHHCCCEEEEECCC
NDPYGKLVTDNLQNEQINTDYIEVEKDGHTGVAMITVTNNDNAIVVAPGANFSWKPEEAA
CCCCCCEEECCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHH
QYRDVFKQTNVLVLQLEVPLPFIEEIAKIGKEERCIVILNPAPAQPLPSSLLDLVDYITP
HHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC
NETECQTIFKQSVEQAVQRYPNKLLVTEGKKGAAYHDGQQLVQVNGFPANVVDTTGAGDT
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCCCEEECCCCCCC
FNGALAAALASGQQLAEAVTFANAAASLSVEQAGAQAGMPSKQQVLARLGSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MITVVGSINIDLVVHTGTMPVLGETVLGGEFQTNPGGKGANQAVAAARLGADVTMIGKVG
CEEEEEECEEEEEEECCCCCHHCHHEECCEEECCCCCCCCHHHHHHHHHCCCEEEEECCC
NDPYGKLVTDNLQNEQINTDYIEVEKDGHTGVAMITVTNNDNAIVVAPGANFSWKPEEAA
CCCCCCEEECCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHH
QYRDVFKQTNVLVLQLEVPLPFIEEIAKIGKEERCIVILNPAPAQPLPSSLLDLVDYITP
HHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC
NETECQTIFKQSVEQAVQRYPNKLLVTEGKKGAAYHDGQQLVQVNGFPANVVDTTGAGDT
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCCCEEECCCCCCC
FNGALAAALASGQQLAEAVTFANAAASLSVEQAGAQAGMPSKQQVLARLGSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]