BacMap

Definition	Bacillus clausii KSM-K16, complete genome.
Accession	NC_006582
Length	4,303,871

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The map label for this gene is gno [H]

Identifier: 56965375

GI number: 56965375

Start: 3767091

End: 3767864

Strand: Direct

Name: gno [H]

Synonym: ABC3613

Alternate gene names: 56965375

Gene position: 3767091-3767864 (Clockwise)

Preceding gene: 56965365

Following gene: 56965376

Centisome position: 87.53

GC content: 47.03

Gene sequence:

>774_bases
TTGACCGTATCTACCATATTTGATTTATCGACGAAACATGCAGTGGTAACTGGCGGTGCCCAAGGCCTTGGTTTTACAAT
CGCAAAGTCATTAGCGGCCTTCGGTTGCGACATAGCCATTGTAGACATTGACGCTGAAGCTGCTGCAAAGGCAGCACAAG
AAATTACAACTACTTATTCGGTCAACACACAGTCGATTCAAGCGGATGTCAGCAAAGAGGAAGAAGTCAGCGCCATGGTT
GATCGTGTATTGGAATCATTTCCACAAATCGATGTGCTCGTCAATAACGCAGGGATTGTAAAGAAAATCGATACATTGGA
CATGACATACAGCGATTGGAAGCGAACGATGGATGTGAACATAAACGCTTTATTCCTAACATCTAAGCAGGTTGGCAAAC
ATATGGTCGCTAATGGGTCAGGCTCGATTATGAACATGTCTTCCATGTCTGCGATGATTGCCAATCGGGAAGCACAGAGT
GCGTACAATGCCTCTAAAGGCGCGGTCAGTATGCTGACCAAATCACTCGCTTCAGAATGGGCGCAATATGGGATACGTGT
CAATGCGATAGCACCTGGCTATATGGCCTCGCAAATGACAGGGCCGTTATTCGCGCCTGGCGGGGAGCTCGAACACATCC
TAGAACACGTTCCGATGAAACGCCTTGGTCGTCCAGATGAATTAAGCGGCATAGCTGTTTATTTAGCATCTGACGCATCT
AGTTTTACAACTGGCTCCATCATCGTTGTGGATGGCGGCTATACCACATGGTAA

Upstream 100 bases:

>100_bases
AAATAAAACAAAAGTATTCAACAAAAATATTGACATAAACGAAAACAATGTTATGATTTTCAATATCTGATTTGAAAACG
CTTACGAAAGGGGTGGTCGT

Downstream 100 bases:

>100_bases
ACGATAAAGCACATACAGGAGGAAAACACGATGAACGATTCAATTCCTAAAAAAATGAAAGCGGTTGTCGCTTACGGCCC
GAAAGATTATCGATTGGAAG

Product: oxidoreductase

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTVSTIFDLSTKHAVVTGGAQGLGFTIAKSLAAFGCDIAIVDIDAEAAAKAAQEITTTYSVNTQSIQADVSKEEEVSAMV
DRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQVGKHMVANGSGSIMNMSSMSAMIANREAQS
AYNASKGAVSMLTKSLASEWAQYGIRVNAIAPGYMASQMTGPLFAPGGELEHILEHVPMKRLGRPDELSGIAVYLASDAS
SFTTGSIIVVDGGYTTW

Sequences:

>Translated_257_residues
MTVSTIFDLSTKHAVVTGGAQGLGFTIAKSLAAFGCDIAIVDIDAEAAAKAAQEITTTYSVNTQSIQADVSKEEEVSAMV
DRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQVGKHMVANGSGSIMNMSSMSAMIANREAQS
AYNASKGAVSMLTKSLASEWAQYGIRVNAIAPGYMASQMTGPLFAPGGELEHILEHVPMKRLGRPDELSGIAVYLASDAS
SFTTGSIIVVDGGYTTW
>Mature_256_residues
TVSTIFDLSTKHAVVTGGAQGLGFTIAKSLAAFGCDIAIVDIDAEAAAKAAQEITTTYSVNTQSIQADVSKEEEVSAMVD
RVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQVGKHMVANGSGSIMNMSSMSAMIANREAQSA
YNASKGAVSMLTKSLASEWAQYGIRVNAIAPGYMASQMTGPLFAPGGELEHILEHVPMKRLGRPDELSGIAVYLASDASS
FTTGSIIVVDGGYTTW

Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=32.8063241106719, Blast_Score=131, Evalue=5e-31,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=32.9411764705882, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=32.6693227091633, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=30.241935483871, Blast_Score=114, Evalue=7e-26,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=30.5785123966942, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=30.9178743961353, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=27.9352226720648, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=29.718875502008, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI59889578, Length=224, Percent_Identity=29.4642857142857, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=30.1587301587302, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI4503301, Length=229, Percent_Identity=25.764192139738, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=29.1338582677165, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=31.413612565445, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=28.7958115183246, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI226371731, Length=194, Percent_Identity=30.9278350515464, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=27.4590163934426, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=30.5699481865285, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=27.5590551181102, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=30.4093567251462, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=32.4324324324324, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI40807363, Length=221, Percent_Identity=26.6968325791855, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7705855, Length=192, Percent_Identity=25.5208333333333, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=30.3664921465969, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4504503, Length=225, Percent_Identity=27.5555555555556, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40254986, Length=185, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=40.1606425702811, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=38, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=37.9446640316205, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=36.144578313253, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=33.739837398374, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=33.739837398374, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=31.1740890688259, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=33.6065573770492, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=31.6602316602317, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=29.9610894941634, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=31.1284046692607, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=27.6422764227642, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=25.4166666666667, Blast_Score=70, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=37.8048780487805, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=35.7429718875502, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.0813008130081, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=31.7073170731707, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=34, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=31.2252964426877, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=30.7984790874525, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=29.5019157088123, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=33.8582677165354, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=30, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.5862068965517, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=27.6923076923077, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=27.7992277992278, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30.8, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561272, Length=235, Percent_Identity=31.4893617021277, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=28.7449392712551, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=26.6409266409266, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=28.2945736434109, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=27.0992366412214, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=26.2548262548263, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=27.3076923076923, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=29.0697674418605, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=27.9693486590038, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=25.7575757575758, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=25.1968503937008, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=237, Percent_Identity=29.1139240506329, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=24.904214559387, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=25.3846153846154, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=24.3445692883895, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=24.8091603053435, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=228, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=226, Percent_Identity=26.1061946902655, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=25.6410256410256, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=25.6544502617801, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=25.2, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193207185, Length=145, Percent_Identity=26.8965517241379, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=186, Percent_Identity=28.494623655914, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=30.4878048780488, Blast_Score=96, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322861, Length=249, Percent_Identity=27.3092369477912, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=30.1980198019802, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=32.6612903225806, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=34.8178137651822, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.4661354581673, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=30.9803921568627, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=31.8725099601594, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.1960784313725, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=31.6, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI161076933, Length=188, Percent_Identity=30.3191489361702, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24584748, Length=188, Percent_Identity=30.3191489361702, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=29.0697674418605, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=29.6875, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584744, Length=213, Percent_Identity=28.169014084507, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574402, Length=213, Percent_Identity=28.169014084507, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281364892, Length=211, Percent_Identity=30.8056872037915, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=26.1627906976744, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=27.1276595744681, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640442, Length=213, Percent_Identity=29.5774647887324, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=27.7227722772277, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=30.8080808080808, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=30.8080808080808, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18859837, Length=248, Percent_Identity=26.2096774193548, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221510726, Length=197, Percent_Identity=30.9644670050761, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581726, Length=216, Percent_Identity=26.8518518518519, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665247, Length=199, Percent_Identity=30.6532663316583, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 27262; Mature: 27131

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSTIFDLSTKHAVVTGGAQGLGFTIAKSLAAFGCDIAIVDIDAEAAAKAAQEITTTYS
CCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHEEE
VNTQSIQADVSKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVN
CCHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHCCCCHHHHHEEEECC
INALFLTSKQVGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLASEW
EEEEEEECHHHCCCEEECCCCCEEEHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHH
AQYGIRVNAIAPGYMASQMTGPLFAPGGELEHILEHVPMKRLGRPDELSGIAVYLASDAS
HHCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCC
SFTTGSIIVVDGGYTTW
CCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TVSTIFDLSTKHAVVTGGAQGLGFTIAKSLAAFGCDIAIVDIDAEAAAKAAQEITTTYS
CCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHEEE
VNTQSIQADVSKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVN
CCHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHCCCCHHHHHEEEECC
INALFLTSKQVGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLASEW
EEEEEEECHHHCCCEEECCCCCEEEHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHH
AQYGIRVNAIAPGYMASQMTGPLFAPGGELEHILEHVPMKRLGRPDELSGIAVYLASDAS
HHCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCC
SFTTGSIIVVDGGYTTW
CCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751271 [H]