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The map label for this gene is rbsK [H]

Identifier: 56965365

GI number: 56965365

Start: 3757537

End: 3758412

Strand: Direct

Name: rbsK [H]

Synonym: ABC3603

Alternate gene names: 56965365

Gene position: 3757537-3758412 (Clockwise)

Preceding gene: 56965363

Following gene: 56965375

Centisome position: 87.31

GC content: 49.89

Gene sequence:

>876_bases
TTGATCGCCATTGTTGGAAGCATCAACATCGACCTTGTCGTTTACACAAGTAATATGCCTGTGCCTGGGGAAACCGTGCT
CGGCGACAAGTTTCGAACCAATCCAGGAGGGAAAGGAGCCAATCAAGCCGTTGCTGCTGCCAGGCTAGGTGCTGCGGTAA
CAATGGTAGGCCGGGTTGGCAATGATCCGTATGGAAAGCTTGCGACTGAGAACTTGAGAAACGAACAAGTGGAAACAGGC
TACATAGACGTGGACAACGCGGCACATACCGGCGTGGCAATGATTACTGTCACAAATAATGACAATTCTATTGTGGTCGC
TCCTGGCGCTAATTTTAGCTGGAAGCGCGAGGAGGCAGGGCTGTACCGGGAACTGTTGCGGCAATCAAAAGTCCTGCTTC
TTCAACTTGAAGTACCGCTGCCTTTTATTGAAGAGATCGCAAAACTTGGCAAGGAAGAACAATGCACCACAATTCTAAAC
CCTGCCCCCGCCCAACAGTTATCGCCGTCCATGCTTGATCTAGTCGACTTTATAACGCCAAATGAAACAGAGTGCCAAAC
CATCTTTAAACAACCAGTTGAACAAGCGGTTCGGAACTATCCCAATAAGCTGATTGTGACAGAAGGAAAAAAAGGCGCCA
CCTACCATGATGGCAACCGTCTTGTCCGCGTCAATGGATTTTTAGCAAAAGCTGTCGATACGACTGGCGCTGGAGACACA
TTTAACGGTGCCTTTGCTGCCGCTTTGGCATCCGAACATCCATTAGCTGAAGCAGTGTCCTTCGCCAACGCCGCTGCCTC
GCTTTCCGTTGAAAAAGCAGGAGCACAATCCGGCATGCCTACAAAAAAGCAAGTAGTGCATCGCCTAGGCACCTGA

Upstream 100 bases:

>100_bases
CAAAAGGCAAGATACTTTTATACGAGTTATGATATTAGGACTTACTTTAGGAAAACGTTTTATTGTAAAATAGAGGTATT
CGGGAAAGGAGGCGTTTGCA

Downstream 100 bases:

>100_bases
CACACCAAACGCCCTTTCCTTAAGCGGAAGGGGCGTTATTTTTAGGGTTTCGTCTAAACATAGGAATTAAAACTGAAAGT
CCAGCTATGACAAATAAGGC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIAIVGSINIDLVVYTSNMPVPGETVLGDKFRTNPGGKGANQAVAAARLGAAVTMVGRVGNDPYGKLATENLRNEQVETG
YIDVDNAAHTGVAMITVTNNDNSIVVAPGANFSWKREEAGLYRELLRQSKVLLLQLEVPLPFIEEIAKLGKEEQCTTILN
PAPAQQLSPSMLDLVDFITPNETECQTIFKQPVEQAVRNYPNKLIVTEGKKGATYHDGNRLVRVNGFLAKAVDTTGAGDT
FNGAFAAALASEHPLAEAVSFANAAASLSVEKAGAQSGMPTKKQVVHRLGT

Sequences:

>Translated_291_residues
MIAIVGSINIDLVVYTSNMPVPGETVLGDKFRTNPGGKGANQAVAAARLGAAVTMVGRVGNDPYGKLATENLRNEQVETG
YIDVDNAAHTGVAMITVTNNDNSIVVAPGANFSWKREEAGLYRELLRQSKVLLLQLEVPLPFIEEIAKLGKEEQCTTILN
PAPAQQLSPSMLDLVDFITPNETECQTIFKQPVEQAVRNYPNKLIVTEGKKGATYHDGNRLVRVNGFLAKAVDTTGAGDT
FNGAFAAALASEHPLAEAVSFANAAASLSVEKAGAQSGMPTKKQVVHRLGT
>Mature_291_residues
MIAIVGSINIDLVVYTSNMPVPGETVLGDKFRTNPGGKGANQAVAAARLGAAVTMVGRVGNDPYGKLATENLRNEQVETG
YIDVDNAAHTGVAMITVTNNDNSIVVAPGANFSWKREEAGLYRELLRQSKVLLLQLEVPLPFIEEIAKLGKEEQCTTILN
PAPAQQLSPSMLDLVDFITPNETECQTIFKQPVEQAVRNYPNKLIVTEGKKGATYHDGNRLVRVNGFLAKAVDTTGAGDT
FNGAFAAALASEHPLAEAVSFANAAASLSVEKAGAQSGMPTKKQVVHRLGT

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=35.6902356902357, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1790193, Length=295, Percent_Identity=37.6271186440678, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI87081971, Length=270, Percent_Identity=26.2962962962963, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082343, Length=290, Percent_Identity=28.6206896551724, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788417, Length=310, Percent_Identity=27.0967741935484, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=295, Percent_Identity=37.2881355932203, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319884, Length=333, Percent_Identity=27.3273273273273, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=34.5514950166113, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24583886, Length=314, Percent_Identity=27.3885350318471, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30915; Mature: 30915

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAIVGSINIDLVVYTSNMPVPGETVLGDKFRTNPGGKGANQAVAAARLGAAVTMVGRVG
CEEEEEECEEEEEEEECCCCCCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHEEEECCC
NDPYGKLATENLRNEQVETGYIDVDNAAHTGVAMITVTNNDNSIVVAPGANFSWKREEAG
CCCCCCHHHHHHCCCCCEECEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHH
LYRELLRQSKVLLLQLEVPLPFIEEIAKLGKEEQCTTILNPAPAQQLSPSMLDLVDFITP
HHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCEECCCCCHHHCCHHHHHHHHHCCC
NETECQTIFKQPVEQAVRNYPNKLIVTEGKKGATYHDGNRLVRVNGFLAKAVDTTGAGDT
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCEEEEECCEEEEHHCCCCCCCC
FNGAFAAALASEHPLAEAVSFANAAASLSVEKAGAQSGMPTKKQVVHRLGT
CCHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIAIVGSINIDLVVYTSNMPVPGETVLGDKFRTNPGGKGANQAVAAARLGAAVTMVGRVG
CEEEEEECEEEEEEEECCCCCCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHEEEECCC
NDPYGKLATENLRNEQVETGYIDVDNAAHTGVAMITVTNNDNSIVVAPGANFSWKREEAG
CCCCCCHHHHHHCCCCCEECEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHH
LYRELLRQSKVLLLQLEVPLPFIEEIAKLGKEEQCTTILNPAPAQQLSPSMLDLVDFITP
HHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCCCCCEECCCCCHHHCCHHHHHHHHHCCC
NETECQTIFKQPVEQAVRNYPNKLIVTEGKKGATYHDGNRLVRVNGFLAKAVDTTGAGDT
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCEEEEECCEEEEHHCCCCCCCC
FNGAFAAALASEHPLAEAVSFANAAASLSVEKAGAQSGMPTKKQVVHRLGT
CCHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]