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The map label for this gene is dck [H]

Identifier: 56964654

GI number: 56964654

Start: 3018599

End: 3019228

Strand: Direct

Name: dck [H]

Synonym: ABC2890

Alternate gene names: 56964654

Gene position: 3018599-3019228 (Clockwise)

Preceding gene: 56964653

Following gene: 56964661

Centisome position: 70.14

GC content: 41.43

Gene sequence:

>630_bases
ATGTTACATATTCCTAATAATGCGATCATAACTGTAGCTGGCACAGTCGGAGTTGGAAAAACGACTTTGACGCACGCACT
TGCCGACGAGCTAAATTTTAAAACATCCTTTGAAAAAGTAGACAACAACCCATACTTAGACAAATTTTATCGCGATTTCG
AACGGTGGAGCTTTCACTTGCAAATTTACTTTTTAGCGGAGCGCTTTAAAGAGCAGAAGCGAATGGTAGAAGAAGGTGGT
GGCTATATTCAAGATCGTTCGATCTATGAAGACACAGGCATATTCGCGAAAATGCATGCCGATAAAGGCACGATGACGCA
AACCGATTACCAAACTTATACAAGCTTATTTGAAGCAATGGTGATGACGCCTTACTTTCCCCGCCCGGATGTATTAATCT
ACTTGCATGGCGATTTTGACTCGATTTTAGACCGTATTCAAGCACGAGGGCGCGAAATGGAAAAACAAACGCCCCTTTCT
TATTGGGAAGAAATGTACAACCGTTATGAAACATGGATTTCTTCCTTTTCCGCCTGTCCGGTTTTGCGCCTTGATATTCG
CGAATACGATTTACTTGCTGACCAATCATGTATCAAACGAATTGTTCATGAGCTAAGCACTTATTTCTAA

Upstream 100 bases:

>100_bases
CGGACGACCTTGACTTTGTCGCCAATCCGCATGATTTGGACTTTGTATTTGCCAAAATTGATGCATGCTTGACATCTGTT
AACCAGTAAGGAGCTTACCA

Downstream 100 bases:

>100_bases
CCTAAAAAAACAGCGAAGCTGCCTTCGCTGTTTTTTAATTATTTGTAGAAATAATCGCCGGCTGAAATGCGCTTTCGGCT
CTGTTCGACTTCAATTAATG

Product: deoxypurine kinase

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MLHIPNNAIITVAGTVGVGKTTLTHALADELNFKTSFEKVDNNPYLDKFYRDFERWSFHLQIYFLAERFKEQKRMVEEGG
GYIQDRSIYEDTGIFAKMHADKGTMTQTDYQTYTSLFEAMVMTPYFPRPDVLIYLHGDFDSILDRIQARGREMEKQTPLS
YWEEMYNRYETWISSFSACPVLRLDIREYDLLADQSCIKRIVHELSTYF

Sequences:

>Translated_209_residues
MLHIPNNAIITVAGTVGVGKTTLTHALADELNFKTSFEKVDNNPYLDKFYRDFERWSFHLQIYFLAERFKEQKRMVEEGG
GYIQDRSIYEDTGIFAKMHADKGTMTQTDYQTYTSLFEAMVMTPYFPRPDVLIYLHGDFDSILDRIQARGREMEKQTPLS
YWEEMYNRYETWISSFSACPVLRLDIREYDLLADQSCIKRIVHELSTYF
>Mature_209_residues
MLHIPNNAIITVAGTVGVGKTTLTHALADELNFKTSFEKVDNNPYLDKFYRDFERWSFHLQIYFLAERFKEQKRMVEEGG
GYIQDRSIYEDTGIFAKMHADKGTMTQTDYQTYTSLFEAMVMTPYFPRPDVLIYLHGDFDSILDRIQARGREMEKQTPLS
YWEEMYNRYETWISSFSACPVLRLDIREYDLLADQSCIKRIVHELSTYF

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

Organism=Homo sapiens, GI4503269, Length=242, Percent_Identity=25.6198347107438, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 24675; Mature: 24675

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHIPNNAIITVAGTVGVGKTTLTHALADELNFKTSFEKVDNNPYLDKFYRDFERWSFHL
CEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHE
QIYFLAERFKEQKRMVEEGGGYIQDRSIYEDTGIFAKMHADKGTMTQTDYQTYTSLFEAM
EHHHHHHHHHHHHHHHHHCCCEECCCCCHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VMTPYFPRPDVLIYLHGDFDSILDRIQARGREMEKQTPLSYWEEMYNRYETWISSFSACP
HHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
VLRLDIREYDLLADQSCIKRIVHELSTYF
EEEECHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLHIPNNAIITVAGTVGVGKTTLTHALADELNFKTSFEKVDNNPYLDKFYRDFERWSFHL
CEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHE
QIYFLAERFKEQKRMVEEGGGYIQDRSIYEDTGIFAKMHADKGTMTQTDYQTYTSLFEAM
EHHHHHHHHHHHHHHHHHCCCEECCCCCHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VMTPYFPRPDVLIYLHGDFDSILDRIQARGREMEKQTPLSYWEEMYNRYETWISSFSACP
HHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
VLRLDIREYDLLADQSCIKRIVHELSTYF
EEEECHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]