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The map label for this gene is dgk [H]

Identifier: 56964653

GI number: 56964653

Start: 3017964

End: 3018587

Strand: Direct

Name: dgk [H]

Synonym: ABC2889

Alternate gene names: 56964653

Gene position: 3017964-3018587 (Clockwise)

Preceding gene: 56964647

Following gene: 56964654

Centisome position: 70.12

GC content: 41.35

Gene sequence:

>624_bases
TTGACGACCCCATTTATATGTGTAGAAGGAGTGATTGGCGTCGGAAAGACAACATTGGCCAAAGCGATTGCTACCCACTA
TGGGCGAGAGTGCTTGCTTGAAATCGTTGAAGAAAACCCTTTTCTTGAAAAATTTTATGACAATATGGAGGAATGGAGTT
TTCAAACCGAAATGTTCTTTCTGTGCAACCGCGTCAAACAACTAGAAGATATCGGCCCTGTTCTTAACCACAAACTCGTC
GTGTCGGATTACCATATTTGCAAAAACTTAATTTTTGCCCGCCAAACGCTGTCTGCTTTTAAATGGAGCCAATACCGACG
TATTTTTCAAATTTTAAATGAACCATTGCCAAAGCCAACAGTCGTCATTTACTTAAAAGCAGGCTTGTCCACATTGACCA
ACCGTATTACCAAAAGGGGGCGTCCTTTTGAAAAAGAAATGGACCCCAATTATTTGCGAAAGCTTTCAGACGATTATGAG
GCGACAATGGCAGAACTCGCTAAAGAGGAAAACACAACAGTTTTAACGATTGACACGGACGACCTTGACTTTGTCGCCAA
TCCGCATGATTTGGACTTTGTATTTGCCAAAATTGATGCATGCTTGACATCTGTTAACCAGTAA

Upstream 100 bases:

>100_bases
TTAAGTGTACCACATTTTTTGACGTTGGACTTTCACACTGCTTGACCACAAAACGTGGTACACTAGCACATGTAAACATG
CAAAACGAGGAGGAAACGGA

Downstream 100 bases:

>100_bases
GGAGCTTACCAATGTTACATATTCCTAATAATGCGATCATAACTGTAGCTGGCACAGTCGGAGTTGGAAAAACGACTTTG
ACGCACGCACTTGCCGACGA

Product: deoxypurine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTTPFICVEGVIGVGKTTLAKAIATHYGRECLLEIVEENPFLEKFYDNMEEWSFQTEMFFLCNRVKQLEDIGPVLNHKLV
VSDYHICKNLIFARQTLSAFKWSQYRRIFQILNEPLPKPTVVIYLKAGLSTLTNRITKRGRPFEKEMDPNYLRKLSDDYE
ATMAELAKEENTTVLTIDTDDLDFVANPHDLDFVFAKIDACLTSVNQ

Sequences:

>Translated_207_residues
MTTPFICVEGVIGVGKTTLAKAIATHYGRECLLEIVEENPFLEKFYDNMEEWSFQTEMFFLCNRVKQLEDIGPVLNHKLV
VSDYHICKNLIFARQTLSAFKWSQYRRIFQILNEPLPKPTVVIYLKAGLSTLTNRITKRGRPFEKEMDPNYLRKLSDDYE
ATMAELAKEENTTVLTIDTDDLDFVANPHDLDFVFAKIDACLTSVNQ
>Mature_206_residues
TTPFICVEGVIGVGKTTLAKAIATHYGRECLLEIVEENPFLEKFYDNMEEWSFQTEMFFLCNRVKQLEDIGPVLNHKLVV
SDYHICKNLIFARQTLSAFKWSQYRRIFQILNEPLPKPTVVIYLKAGLSTLTNRITKRGRPFEKEMDPNYLRKLSDDYEA
TMAELAKEENTTVLTIDTDDLDFVANPHDLDFVFAKIDACLTSVNQ

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 23885; Mature: 23754

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPFICVEGVIGVGKTTLAKAIATHYGRECLLEIVEENPFLEKFYDNMEEWSFQTEMFF
CCCCCEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LCNRVKQLEDIGPVLNHKLVVSDYHICKNLIFARQTLSAFKWSQYRRIFQILNEPLPKPT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVIYLKAGLSTLTNRITKRGRPFEKEMDPNYLRKLSDDYEATMAELAKEENTTVLTIDTD
EEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECC
DLDFVANPHDLDFVFAKIDACLTSVNQ
CCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPFICVEGVIGVGKTTLAKAIATHYGRECLLEIVEENPFLEKFYDNMEEWSFQTEMFF
CCCCEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LCNRVKQLEDIGPVLNHKLVVSDYHICKNLIFARQTLSAFKWSQYRRIFQILNEPLPKPT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVIYLKAGLSTLTNRITKRGRPFEKEMDPNYLRKLSDDYEATMAELAKEENTTVLTIDTD
EEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECC
DLDFVANPHDLDFVFAKIDACLTSVNQ
CCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]