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The map label for this gene is ydjN [C]

Identifier: 56964661

GI number: 56964661

Start: 3024871

End: 3026268

Strand: Direct

Name: ydjN [C]

Synonym: ABC2897

Alternate gene names: 56964661

Gene position: 3024871-3026268 (Clockwise)

Preceding gene: 56964654

Following gene: 56964663

Centisome position: 70.28

GC content: 45.64

Gene sequence:

>1398_bases
ATGGACTTGTTCTTAACTTTATTGATTATTGCGATTGTCCTCGCTGTAGCTGGACTGTTGTTTTACATGCAAAAAAAGCA
CGTCTCTTTCTCGATCCGCGTTTTGTTGGCGCTAGGAGCCGGTGTGGTATATGGCCTGTTGCTCCAGTTTTTCTTCGCCC
CTGATTCATCTGTTATTCAACAATCAATGGATTGGGTCAATATTTTAGGGACCGGTTATGTCCGCTTTTTGCAAATGATT
GTCATGCCGTTAATTTTCATTTCGATTCTGTCTGCATTTACACGTATGACGTTAACAAAGAATCTAGGGAAAATTAGCGC
TTTGATTCTTGGCACATTGATTGCTACGACAGCCATTGCCGCTGCTATTGGGATCACTGCTTCATCCGTCTTTCAACTTG
AAGCGATTGACATTCCTGCAGGCGAAGCAGAACTTAGCCACGGCGATGCCCTTGAAGAAAGTTACGCTGGCATGGAAGCA
GCGACATTGCCGCAGCAAATTGTCGAGCTAATCCCTGCTAATCCATTTCTTGACCTAACTGGCGAACGACCGACTTCGGC
AATTGGTGTTGTGATCTTTTCTGCCTTTCTCGGCGTAGCCTATTTAGGTGTACGCCGCAAACAGCCGGAAGCAGCCGACA
CGTTTAAAGGCATTGTCAATGCCCTTTACGCGATCATTATGCGCGTCGTTACATTAATTTTACGGTTGACTCCTTATGGT
GTTTTGGCGATTATGACAAGAACAGTTGCAACAAGTGACCTACAGGCAATTTCGACACTTGGGACGTTTGTGCTTGCTTC
TTATGCCGCACTGATTGTCATGTTTGTTATTCATTTAATCATTCTAGCTGCGACTGGCCTAAGCCCCATTACGTATGTGA
AAAAGGCATTTCCGGTGCTCGCTTTTGCGTTTACGTCACGCACGAGTGCAGGGGCATTGCCAATGAACATCCAAACACAA
AAGAAATTAGGCGTTCCAGAGGGCATTGCCAATTTTGCAGGTTCATTTGGCTTATCAATTGGCCAAAATGGATGTGCTGG
GATTTATCCAGCCATGCTGGCCGTTATGATTGCGCCAACGGTAGGCCAAAATCCTCTAGAACCAACGTTTATTTTGTTGT
TAATTGTGGTCATTGCCATTAGTTCGTTTGGCGTAGCAGGCGTTGGCGGTGGGGCAACTTTCGCTGCCATTCTCGTCTTG
TCCGCACTTGATTTTCCAATTGCCCTTGCCGGCCTCCTTATTTCGATTGAACCACTAATTGACATGGGCCGTACTGCTTT
AAACGTTTCAGGCAGCATGGTGTCCGGCATCTTTACTTCAAAAGTGACAGGGAGCCTTGACAAAGAAGTATTTTCAGATC
CGAACGAACAACTTGATACGCAAGACATGCAAGGTTAA

Upstream 100 bases:

>100_bases
TATGATACACTCACTTCACATATAATTCCCACTTGACTCATATGATTATACAGAATACTATAAAGAACGTTGTATATTTT
AACCAAAGGAGTTTGAGCAT

Downstream 100 bases:

>100_bases
CAAGAAACGCGGCATCTGATTAGATTGCCGCGCTTTTCATATCTCTATTGGCCAAAAAATGGAAGAAGCCAATGGCTTGC
ATACACACAAATAATGCCAA

Product: sodium:dicarboxylate symporter

Products: NA

Alternate protein names: Transporter of cystine tcyP

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MDLFLTLLIIAIVLAVAGLLFYMQKKHVSFSIRVLLALGAGVVYGLLLQFFFAPDSSVIQQSMDWVNILGTGYVRFLQMI
VMPLIFISILSAFTRMTLTKNLGKISALILGTLIATTAIAAAIGITASSVFQLEAIDIPAGEAELSHGDALEESYAGMEA
ATLPQQIVELIPANPFLDLTGERPTSAIGVVIFSAFLGVAYLGVRRKQPEAADTFKGIVNALYAIIMRVVTLILRLTPYG
VLAIMTRTVATSDLQAISTLGTFVLASYAALIVMFVIHLIILAATGLSPITYVKKAFPVLAFAFTSRTSAGALPMNIQTQ
KKLGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPTVGQNPLEPTFILLLIVVIAISSFGVAGVGGGATFAAILVL
SALDFPIALAGLLISIEPLIDMGRTALNVSGSMVSGIFTSKVTGSLDKEVFSDPNEQLDTQDMQG

Sequences:

>Translated_465_residues
MDLFLTLLIIAIVLAVAGLLFYMQKKHVSFSIRVLLALGAGVVYGLLLQFFFAPDSSVIQQSMDWVNILGTGYVRFLQMI
VMPLIFISILSAFTRMTLTKNLGKISALILGTLIATTAIAAAIGITASSVFQLEAIDIPAGEAELSHGDALEESYAGMEA
ATLPQQIVELIPANPFLDLTGERPTSAIGVVIFSAFLGVAYLGVRRKQPEAADTFKGIVNALYAIIMRVVTLILRLTPYG
VLAIMTRTVATSDLQAISTLGTFVLASYAALIVMFVIHLIILAATGLSPITYVKKAFPVLAFAFTSRTSAGALPMNIQTQ
KKLGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPTVGQNPLEPTFILLLIVVIAISSFGVAGVGGGATFAAILVL
SALDFPIALAGLLISIEPLIDMGRTALNVSGSMVSGIFTSKVTGSLDKEVFSDPNEQLDTQDMQG
>Mature_465_residues
MDLFLTLLIIAIVLAVAGLLFYMQKKHVSFSIRVLLALGAGVVYGLLLQFFFAPDSSVIQQSMDWVNILGTGYVRFLQMI
VMPLIFISILSAFTRMTLTKNLGKISALILGTLIATTAIAAAIGITASSVFQLEAIDIPAGEAELSHGDALEESYAGMEA
ATLPQQIVELIPANPFLDLTGERPTSAIGVVIFSAFLGVAYLGVRRKQPEAADTFKGIVNALYAIIMRVVTLILRLTPYG
VLAIMTRTVATSDLQAISTLGTFVLASYAALIVMFVIHLIILAATGLSPITYVKKAFPVLAFAFTSRTSAGALPMNIQTQ
KKLGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPTVGQNPLEPTFILLLIVVIAISSFGVAGVGGGATFAAILVL
SALDFPIALAGLLISIEPLIDMGRTALNVSGSMVSGIFTSKVTGSLDKEVFSDPNEQLDTQDMQG

Specific function: Mediates uptake of L-cystine, the oxidized form of L- cysteine

COG id: COG1823

COG function: function code R; Predicted Na+/dicarboxylate symporter

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI223468564, Length=250, Percent_Identity=26, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI223468566, Length=250, Percent_Identity=26, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI5032093, Length=250, Percent_Identity=26, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788024, Length=459, Percent_Identity=51.19825708061, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1790514, Length=444, Percent_Identity=25, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789947, Length=436, Percent_Identity=25, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193206654, Length=443, Percent_Identity=23.0248306997743, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193206505, Length=439, Percent_Identity=23.2346241457859, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537407, Length=442, Percent_Identity=24.2081447963801, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983106, Length=431, Percent_Identity=22.2737819025522, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983099, Length=431, Percent_Identity=22.2737819025522, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996953, Length=470, Percent_Identity=22.9787234042553, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583025, Length=442, Percent_Identity=24.2081447963801, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17137668, Length=442, Percent_Identity=24.2081447963801, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583023, Length=442, Percent_Identity=24.2081447963801, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TCYP_BACSK (Q5WDX9)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_176392.1
- ProteinModelPortal:   Q5WDX9
- STRING:   Q5WDX9
- EnsemblBacteria:   EBBACT00000046186
- GeneID:   3204836
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC2897
- NMPDR:   fig|66692.3.peg.2786
- eggNOG:   COG1823
- GeneTree:   EBGT00070000032022
- HOGENOM:   HBG739804
- OMA:   AWVMRLV
- BioCyc:   BCLA66692:ABC2897-MONOMER
- InterPro:   IPR001991
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 48931; Mature: 48931

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1eb89e60)-; HASH(0x1f42f014)-; HASH(0x1f3ddc9c)-; HASH(0x1f434150)-; HASH(0x1f43a7f8)-; HASH(0x1f0392fc)-; HASH(0x1f3cd940)-; HASH(0x1f432644)-; HASH(0x1f3f9cbc)-; HASH(0x1f410e04)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFLTLLIIAIVLAVAGLLFYMQKKHVSFSIRVLLALGAGVVYGLLLQFFFAPDSSVIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QSMDWVNILGTGYVRFLQMIVMPLIFISILSAFTRMTLTKNLGKISALILGTLIATTAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIGITASSVFQLEAIDIPAGEAELSHGDALEESYAGMEAATLPQQIVELIPANPFLDLT
HHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEECC
GERPTSAIGVVIFSAFLGVAYLGVRRKQPEAADTFKGIVNALYAIIMRVVTLILRLTPYG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAIMTRTVATSDLQAISTLGTFVLASYAALIVMFVIHLIILAATGLSPITYVKKAFPVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AFAFTSRTSAGALPMNIQTQKKLGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPT
HHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
VGQNPLEPTFILLLIVVIAISSFGVAGVGGGATFAAILVLSALDFPIALAGLLISIEPLI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMGRTALNVSGSMVSGIFTSKVTGSLDKEVFSDPNEQLDTQDMQG
HCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHCCCCCCCH
>Mature Secondary Structure
MDLFLTLLIIAIVLAVAGLLFYMQKKHVSFSIRVLLALGAGVVYGLLLQFFFAPDSSVIQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QSMDWVNILGTGYVRFLQMIVMPLIFISILSAFTRMTLTKNLGKISALILGTLIATTAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIGITASSVFQLEAIDIPAGEAELSHGDALEESYAGMEAATLPQQIVELIPANPFLDLT
HHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCEECC
GERPTSAIGVVIFSAFLGVAYLGVRRKQPEAADTFKGIVNALYAIIMRVVTLILRLTPYG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VLAIMTRTVATSDLQAISTLGTFVLASYAALIVMFVIHLIILAATGLSPITYVKKAFPVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AFAFTSRTSAGALPMNIQTQKKLGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPT
HHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
VGQNPLEPTFILLLIVVIAISSFGVAGVGGGATFAAILVLSALDFPIALAGLLISIEPLI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMGRTALNVSGSMVSGIFTSKVTGSLDKEVFSDPNEQLDTQDMQG
HCCCHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA