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The map label for this gene is ykuT [H]

Identifier: 56964194

GI number: 56964194

Start: 2556802

End: 2557581

Strand: Direct

Name: ykuT [H]

Synonym: ABC2429

Alternate gene names: 56964194

Gene position: 2556802-2557581 (Clockwise)

Preceding gene: 56964190

Following gene: 56964202

Centisome position: 59.41

GC content: 47.95

Gene sequence:

>780_bases
GTGAACAGTACTATTAACGAATGGCTTTCCCATCCGCTTGTGCATACCGTTTGGAAAATTGCGCTTGTGGTCATCATTTT
TTTCATCGTGCGCGCCTTAGGGCGCAAACTGATCGCCGGGGCATTTAACCGTTCTATCCGCGCATCACAAGCTCGACTGA
AAACGTTAAAAAGCCTGACTCAAAATGTATTTTCTTATGTGTTGTTGTTTATTGTAGCAATGACGATCTTAGAAATACTC
GGTTTCAATTTAGGGCCGATTTTAGCTGGTGCAGGTGTTGTAGGGCTTGCCGTTGGTTTCGGCGCACAAGGCCTTGTAAG
CGATGTGGTGACTGGCTTTTTCTTATTGTTAGAACGTCAGCTTGAAGTCGGCGATTATGTGACTGCTGGCGGCGTTGAAG
GGATTGTCGAAGAACTCGGCTTCCGCACGACGTTGATTCGCGGTTTTGACGGTACACTCCACTACGTGCCAAACCGCAAC
ATTGCCAATGTGGACAACCATTCCCGCGGCAATATGCGTGCCCTCGTCGACATTTCCATCCCAGCTGGGCAAAAATTAGA
CGAATCGCTAGCAATGGTGAAAGAGGCACTAGAAAACTTTAGCCATCCAGCTATTGTATCTGGCCCTGACGTGTTAGGCG
TCGAAAGCGACGATTTAGCGACGACGACAATCCGTGTGATTGCCAAAACGGATAATATGGAGCAATGGGCAGTGGAACGC
GAAATCCGCCAAGCGATCCGGCAACGATACGATGCCTTTTCACAATCAGAAAATGAATAA

Upstream 100 bases:

>100_bases
CTTCACATTCCTGCCTTACTTACATAGCGGTCTTTGAAAGATTTGTCGATTTATGCTATTCTCAACAAAGCAATGATATT
GAGGAAGGAGCGGGTTATCA

Downstream 100 bases:

>100_bases
AAAAATACCAGCAAAAGCTGGTATTTTTTTAGTGTTGAGTCACAATTTCGTCGACACGTTGGCCGATTTCTTCTGCGCTT
AAACCTTCTGCGTGGATAAT

Product: mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNSTINEWLSHPLVHTVWKIALVVIIFFIVRALGRKLIAGAFNRSIRASQARLKTLKSLTQNVFSYVLLFIVAMTILEIL
GFNLGPILAGAGVVGLAVGFGAQGLVSDVVTGFFLLLERQLEVGDYVTAGGVEGIVEELGFRTTLIRGFDGTLHYVPNRN
IANVDNHSRGNMRALVDISIPAGQKLDESLAMVKEALENFSHPAIVSGPDVLGVESDDLATTTIRVIAKTDNMEQWAVER
EIRQAIRQRYDAFSQSENE

Sequences:

>Translated_259_residues
MNSTINEWLSHPLVHTVWKIALVVIIFFIVRALGRKLIAGAFNRSIRASQARLKTLKSLTQNVFSYVLLFIVAMTILEIL
GFNLGPILAGAGVVGLAVGFGAQGLVSDVVTGFFLLLERQLEVGDYVTAGGVEGIVEELGFRTTLIRGFDGTLHYVPNRN
IANVDNHSRGNMRALVDISIPAGQKLDESLAMVKEALENFSHPAIVSGPDVLGVESDDLATTTIRVIAKTDNMEQWAVER
EIRQAIRQRYDAFSQSENE
>Mature_259_residues
MNSTINEWLSHPLVHTVWKIALVVIIFFIVRALGRKLIAGAFNRSIRASQARLKTLKSLTQNVFSYVLLFIVAMTILEIL
GFNLGPILAGAGVVGLAVGFGAQGLVSDVVTGFFLLLERQLEVGDYVTAGGVEGIVEELGFRTTLIRGFDGTLHYVPNRN
IANVDNHSRGNMRALVDISIPAGQKLDESLAMVKEALENFSHPAIVSGPDVLGVESDDLATTTIRVIAKTDNMEQWAVER
EIRQAIRQRYDAFSQSENE

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=244, Percent_Identity=28.6885245901639, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787591, Length=144, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789291, Length=245, Percent_Identity=25.3061224489796, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786670, Length=156, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 28378; Mature: 28378

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTINEWLSHPLVHTVWKIALVVIIFFIVRALGRKLIAGAFNRSIRASQARLKTLKSLT
CCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVFSYVLLFIVAMTILEILGFNLGPILAGAGVVGLAVGFGAQGLVSDVVTGFFLLLERQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEVGDYVTAGGVEGIVEELGFRTTLIRGFDGTLHYVPNRNIANVDNHSRGNMRALVDISI
HHHCCCHHHCCHHHHHHHHCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEC
PAGQKLDESLAMVKEALENFSHPAIVSGPDVLGVESDDLATTTIRVIAKTDNMEQWAVER
CCCCHHHHHHHHHHHHHHHCCCCCEECCCCEECCCCCCHHHHHHHEEECCCCHHHHHHHH
EIRQAIRQRYDAFSQSENE
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNSTINEWLSHPLVHTVWKIALVVIIFFIVRALGRKLIAGAFNRSIRASQARLKTLKSLT
CCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVFSYVLLFIVAMTILEILGFNLGPILAGAGVVGLAVGFGAQGLVSDVVTGFFLLLERQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEVGDYVTAGGVEGIVEELGFRTTLIRGFDGTLHYVPNRNIANVDNHSRGNMRALVDISI
HHHCCCHHHCCHHHHHHHHCHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEC
PAGQKLDESLAMVKEALENFSHPAIVSGPDVLGVESDDLATTTIRVIAKTDNMEQWAVER
CCCCHHHHHHHHHHHHHHHCCCCCEECCCCEECCCCCCHHHHHHHEEECCCCHHHHHHHH
EIRQAIRQRYDAFSQSENE
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]