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The map label for this gene is rnjA [H]

Identifier: 56964190

GI number: 56964190

Start: 2553018

End: 2554685

Strand: Direct

Name: rnjA [H]

Synonym: ABC2425

Alternate gene names: 56964190

Gene position: 2553018-2554685 (Clockwise)

Preceding gene: 56964189

Following gene: 56964194

Centisome position: 59.32

GC content: 44.9

Gene sequence:

>1668_bases
ATGAAACAAGTAAAAAACAACCAAACAGCTGTTTTCGCTTTAGGCGGCTTAGGCGAAATTGGCAAAAATACGTACGGTGT
TCAGTTCCAAGACGAAATTATTCTTATTGATGCTGGAATTATGTTTCCTCAAGACGAGCTTCTTGGCATCGATTATGTCA
TTCCCGACTATACGTACTTAATCAAAAATCGGGACAAAATCAAAGGCTTGTTTATTACCCATGGCCATGAAGACCATATC
GGCGGAATTCCTTATTTGTTGCGGGAAATCAACATTGATGTCTATGGCGGCAAGCTTGCACTCGGCCTCTTAAAAGGAAA
ACTTGAAGAACACGGCTTGCTACGCAGCGCTAAGCTTCACGAGATTGCAGAAGACCAAGTCGTCAAATTCACGAAAACAT
CGGTGTCGTTTTTCCGGACAACCCATAGCATTCCTGACTCATACGGCGTTGTTGTCAAAACGCCACCAGGAAACATTGTC
CATACAGGCGATTTTAAATTTGACTTTACTCCTGTTGGCGAACCGGCAAATTTAACGAAAATGGCGAAAATCGGCGATGA
AGGCGTACTTTGCTTGCTGTCTGACAGCACCAATAGCGAAATTCCGACTTTTACAATGTCCGAACGAAAAGTAGGCGAAA
GCATCAACAACGTTTTCCAAAAAGTCGATGGGCGCATTATTTTTGCCACGTTCGCTTCGAATATCCATCGCTTGCAACAA
GTGATCCAGGCCGCAGTTGACTACGGCCGCAAAGTATGTGTATTTGGCCGCAGCATGGAATCAGCCATTACCATTGGCCA
AGAGCTTGGCTACATCAATGCGCCTAAACATACATTCATTGAGCACTCACAGTTAAACAAACTCCCTGATAACAAAGTAA
CGATTCTTTGCACAGGAAGCCAAGGTGAACCGATGGCAGCCCTATCACGGATAGCTTTTGGAACACACCGCCAAATTCAA
ATTATTCCAGGGGATACGGTTGTGTTTTCTTCTTCGCCAATTCCAGGAAACACGCTTAGCGTTGGAAAAATCATCAACCA
ACTATACCGTGTTGGCGCAAATGTCATCCATGGCCCACTTAGTGATATCCATACTTCTGGGCACGGCGGGCAGGAAGAAC
AGAAACTGATGTTGCGGCTTATGAAACCGCAATACTTCTTACCCATCCATGGCGAATATCGGATGCTGCGCACTCATAAC
CGCCTCGCTCAAGACTGTGGCGTTAAAGAAGAAAACTGTTTTATTATGGATAACGGCGATGTCCTCGCGCTCCATCCTAA
TGAAGCAGGGGTCGTCGGCAAAATTCCGTCTGGCTCTGTTTATGTGGATGGGAATGGCATCGGCGATATTGGCAATATCG
TGCTTCGTGACCGCCGAATTCTCTCAGAGGAAGGCTTAGTCATCGTTGTCGTTAGCTTAGATATGAAGGAATTCAAAGTC
ACAGCTGGGCCAGATATCATTTCCCGCGGTTTTGTGTACATGAGGGAATCAGGCGATTTGATTCATGAAGCCCAAAAAAT
GCTCGCTAAACATTTAAACAGCGTCATGGAAAAGAAAACGTCTCAGTGGTCTGAAATTAAAAACGAAATGACCGAGCTTC
TCGGACCATTTTTGTACGAGCGTACGAAACGCAAACCGATGATTTTGCCGATTATCATGGAAGTATAA

Upstream 100 bases:

>100_bases
CCAAGCAAAACTTCAACATTGAATACGTAACAGCTGTAACTGGAGCATATTTAGAATATGAGCAGGCAAACAGCGACTTT
AAGGTCGTGAACATTTAACC

Downstream 100 bases:

>100_bases
CAACAAGCCTGCTGACAATGAAAGCCATTGTCGGCAGGCTTGTTTAGCAGCTATTAGTTGGCAATAAAGTCTTTTTCAAA
TGCATAAATGGCTTTTTTTG

Product: metallo-beta-lactamase superfamily hydrolase

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MKQVKNNQTAVFALGGLGEIGKNTYGVQFQDEIILIDAGIMFPQDELLGIDYVIPDYTYLIKNRDKIKGLFITHGHEDHI
GGIPYLLREINIDVYGGKLALGLLKGKLEEHGLLRSAKLHEIAEDQVVKFTKTSVSFFRTTHSIPDSYGVVVKTPPGNIV
HTGDFKFDFTPVGEPANLTKMAKIGDEGVLCLLSDSTNSEIPTFTMSERKVGESINNVFQKVDGRIIFATFASNIHRLQQ
VIQAAVDYGRKVCVFGRSMESAITIGQELGYINAPKHTFIEHSQLNKLPDNKVTILCTGSQGEPMAALSRIAFGTHRQIQ
IIPGDTVVFSSSPIPGNTLSVGKIINQLYRVGANVIHGPLSDIHTSGHGGQEEQKLMLRLMKPQYFLPIHGEYRMLRTHN
RLAQDCGVKEENCFIMDNGDVLALHPNEAGVVGKIPSGSVYVDGNGIGDIGNIVLRDRRILSEEGLVIVVVSLDMKEFKV
TAGPDIISRGFVYMRESGDLIHEAQKMLAKHLNSVMEKKTSQWSEIKNEMTELLGPFLYERTKRKPMILPIIMEV

Sequences:

>Translated_555_residues
MKQVKNNQTAVFALGGLGEIGKNTYGVQFQDEIILIDAGIMFPQDELLGIDYVIPDYTYLIKNRDKIKGLFITHGHEDHI
GGIPYLLREINIDVYGGKLALGLLKGKLEEHGLLRSAKLHEIAEDQVVKFTKTSVSFFRTTHSIPDSYGVVVKTPPGNIV
HTGDFKFDFTPVGEPANLTKMAKIGDEGVLCLLSDSTNSEIPTFTMSERKVGESINNVFQKVDGRIIFATFASNIHRLQQ
VIQAAVDYGRKVCVFGRSMESAITIGQELGYINAPKHTFIEHSQLNKLPDNKVTILCTGSQGEPMAALSRIAFGTHRQIQ
IIPGDTVVFSSSPIPGNTLSVGKIINQLYRVGANVIHGPLSDIHTSGHGGQEEQKLMLRLMKPQYFLPIHGEYRMLRTHN
RLAQDCGVKEENCFIMDNGDVLALHPNEAGVVGKIPSGSVYVDGNGIGDIGNIVLRDRRILSEEGLVIVVVSLDMKEFKV
TAGPDIISRGFVYMRESGDLIHEAQKMLAKHLNSVMEKKTSQWSEIKNEMTELLGPFLYERTKRKPMILPIIMEV
>Mature_555_residues
MKQVKNNQTAVFALGGLGEIGKNTYGVQFQDEIILIDAGIMFPQDELLGIDYVIPDYTYLIKNRDKIKGLFITHGHEDHI
GGIPYLLREINIDVYGGKLALGLLKGKLEEHGLLRSAKLHEIAEDQVVKFTKTSVSFFRTTHSIPDSYGVVVKTPPGNIV
HTGDFKFDFTPVGEPANLTKMAKIGDEGVLCLLSDSTNSEIPTFTMSERKVGESINNVFQKVDGRIIFATFASNIHRLQQ
VIQAAVDYGRKVCVFGRSMESAITIGQELGYINAPKHTFIEHSQLNKLPDNKVTILCTGSQGEPMAALSRIAFGTHRQIQ
IIPGDTVVFSSSPIPGNTLSVGKIINQLYRVGANVIHGPLSDIHTSGHGGQEEQKLMLRLMKPQYFLPIHGEYRMLRTHN
RLAQDCGVKEENCFIMDNGDVLALHPNEAGVVGKIPSGSVYVDGNGIGDIGNIVLRDRRILSEEGLVIVVVSLDMKEFKV
TAGPDIISRGFVYMRESGDLIHEAQKMLAKHLNSVMEKKTSQWSEIKNEMTELLGPFLYERTKRKPMILPIIMEV

Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 61464; Mature: 61464

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVKNNQTAVFALGGLGEIGKNTYGVQFQDEIILIDAGIMFPQDELLGIDYVIPDYTYL
CCCCCCCCEEEEEECCCCCCCCCCCCEEEECCEEEEECCCCCCCHHHEEEEEECCCEEEE
IKNRDKIKGLFITHGHEDHIGGIPYLLREINIDVYGGKLALGLLKGKLEEHGLLRSAKLH
ECCCCCEEEEEEECCCCCCCCCHHHHHHHCCEEEECCCEEEHHHHHHHHHCCCHHHHHHH
EIAEDQVVKFTKTSVSFFRTTHSIPDSYGVVVKTPPGNIVHTGDFKFDFTPVGEPANLTK
HHHHHHHEEEEHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCEEEEECCCCCCCCHH
MAKIGDEGVLCLLSDSTNSEIPTFTMSERKVGESINNVFQKVDGRIIFATFASNIHRLQQ
HHHCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHH
VIQAAVDYGRKVCVFGRSMESAITIGQELGYINAPKHTFIEHSQLNKLPDNKVTILCTGS
HHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCHHHHCHHHHCCCCCCCEEEEEECC
QGEPMAALSRIAFGTHRQIQIIPGDTVVFSSSPIPGNTLSVGKIINQLYRVGANVIHGPL
CCCHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHCCCCH
SDIHTSGHGGQEEQKLMLRLMKPQYFLPIHGEYRMLRTHNRLAQDCGVKEENCFIMDNGD
HHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHCCCCCCCEEEEECCC
VLALHPNEAGVVGKIPSGSVYVDGNGIGDIGNIVLRDRRILSEEGLVIVVVSLDMKEFKV
EEEECCCCCCEEEECCCCCEEECCCCCCCHHHHEECCCHHHCCCCEEEEEEECCHHHEEE
TAGPDIISRGFVYMRESGDLIHEAQKMLAKHLNSVMEKKTSQWSEIKNEMTELLGPFLYE
ECCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTKRKPMILPIIMEV
HHCCCCEEEEEEEEC
>Mature Secondary Structure
MKQVKNNQTAVFALGGLGEIGKNTYGVQFQDEIILIDAGIMFPQDELLGIDYVIPDYTYL
CCCCCCCCEEEEEECCCCCCCCCCCCEEEECCEEEEECCCCCCCHHHEEEEEECCCEEEE
IKNRDKIKGLFITHGHEDHIGGIPYLLREINIDVYGGKLALGLLKGKLEEHGLLRSAKLH
ECCCCCEEEEEEECCCCCCCCCHHHHHHHCCEEEECCCEEEHHHHHHHHHCCCHHHHHHH
EIAEDQVVKFTKTSVSFFRTTHSIPDSYGVVVKTPPGNIVHTGDFKFDFTPVGEPANLTK
HHHHHHHEEEEHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCEEEEECCCCCCCCHH
MAKIGDEGVLCLLSDSTNSEIPTFTMSERKVGESINNVFQKVDGRIIFATFASNIHRLQQ
HHHCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHH
VIQAAVDYGRKVCVFGRSMESAITIGQELGYINAPKHTFIEHSQLNKLPDNKVTILCTGS
HHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCHHHHCHHHHCCCCCCCEEEEEECC
QGEPMAALSRIAFGTHRQIQIIPGDTVVFSSSPIPGNTLSVGKIINQLYRVGANVIHGPL
CCCHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHCCCCH
SDIHTSGHGGQEEQKLMLRLMKPQYFLPIHGEYRMLRTHNRLAQDCGVKEENCFIMDNGD
HHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEHHHHHHHHHHCCCCCCCEEEEECCC
VLALHPNEAGVVGKIPSGSVYVDGNGIGDIGNIVLRDRRILSEEGLVIVVVSLDMKEFKV
EEEECCCCCCEEEECCCCCEEECCCCCCCHHHHEECCCHHHCCCCEEEEEEECCHHHEEE
TAGPDIISRGFVYMRESGDLIHEAQKMLAKHLNSVMEKKTSQWSEIKNEMTELLGPFLYE
ECCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTKRKPMILPIIMEV
HHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]