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The map label for this gene is dsdA

Identifier: 56963719

GI number: 56963719

Start: 2069421

End: 2070743

Strand: Direct

Name: dsdA

Synonym: ABC1954

Alternate gene names: 56963719

Gene position: 2069421-2070743 (Clockwise)

Preceding gene: 56963717

Following gene: 56963720

Centisome position: 48.08

GC content: 49.28

Gene sequence:

>1323_bases
GTGGACATAGCAGGCAAAAACAGAGAGCAATGGTTGGCAGCTTACCCACTTTTACAACAAATTGTATTGACAAAGGAAGT
GTGGTGGGCCAATCCGAACAGGCAGCCTGCTAGCGAAGGGCTAGCACGCCTTTCTTTAAAGGAAGAGGACGTGAAGGAAG
CAGAACAGCGGTTGCGACGCTTTGCCCCATACATAGCAAGCGTGTTTCCGGAAACGAAAGGGGCAGGGGGCTTGATCGAA
TCGCCGCTTATCGACATTCCCACAATGAAGCACAAGCTTGACCAACGATTTGGCCAAAACGTGCCAGGCCGACTTTTGCT
GAAAGGCGATCACGCGCTGCCTATTTCAGGCTCCATTAAAGCGCGGGGCGGTATTTATGAAGTGTTGAAACATGCGGAAA
GCTTGTTGGTCGACCAACAAATTCTCACTAAACAAGACGATTATTCATTGATCGCCACTGACGCAGTCCAATCGTTTTTC
TCGTCTTATGCCATTGTTGTTGGATCAACAGGTAATTTAGGATTAAGCATTGGCATCATTAGCGCAAAGCTAGGTTTTCG
CGTGACGGTACACATGTCAGATGATGCAAAGCAATGGAAAAAAGACATGTTGCGAGAAAAAGGCGTGCGTGTGGTCGAAC
ATTCCGCCGATTACAGCAAGGCAGTCGAAGAGGGAAGAAAAGAATCAGACGCCGATCCGAACAGCTATTTTATTGATGAC
GAACATTCAATTGATCTATTTGTAGGGTATGCTGTCGCTGCATTTCGCTTAAAAGAACAGTTGCAGGAAAAGGGAATTGC
CGTCACAAAAGACCAACCGCTCCACGTCTATCTTCCATGTGGCGTTGGCGGCGGTCCTGGCGGGGTTGCTTTCGGCTTGA
AGCTCGTTTTCGGTGACGCTGTCCGCTGTTTTTTCGCAGAGCCTACCCATTCGCCATGTATGTTAATTGGTATGTTAACT
GGAAAGCACCAGCACATTTCTGTCCAAGACTTTGGAATCGACAACCAAACAGCAGCCGACGGTCTTGCGGTAGGGAGACC
GTCTGGCTTTGTTGGCCGCATGATGGCTCCATTGCTTGAGGGCATCTACACAATCGCCGACCCGATGCTTTATACACTCT
TGGCTGATCTCGCCGACGCAGAAGGCCTCTATTTGGAGCCATCAGCAGTTGCGGGATTATACGGCCCTGTACAGCTTGAA
AAGAGAGGGCTATATACCGATGCAGCGACTCATCTTGTCTGGGCGACAGGAGGAAGCATGGTGCCTAAAGAGATCATGGA
AACGGATTACCAACTAGGTGTCAACTTACGGACTGAGCAGTAG

Upstream 100 bases:

>100_bases
AGTGTCGTTCCCATTTACGATGTGCATTTACAAACAGGAATATCCCGAGCCGGATTGTTCTTACATGTGCTAAAGTTAAA
GAAAAAAGGAGGGGATAAAC

Downstream 100 bases:

>100_bases
ATTGAGTGCCAATACTCACGCCGAGGTACAGAAAGCAAAACGGTACTGGTTTTCTCTTATCTATGCTACACTGGGCACTG
GATAAAGAGAGAGGGAGTAC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MDIAGKNREQWLAAYPLLQQIVLTKEVWWANPNRQPASEGLARLSLKEEDVKEAEQRLRRFAPYIASVFPETKGAGGLIE
SPLIDIPTMKHKLDQRFGQNVPGRLLLKGDHALPISGSIKARGGIYEVLKHAESLLVDQQILTKQDDYSLIATDAVQSFF
SSYAIVVGSTGNLGLSIGIISAKLGFRVTVHMSDDAKQWKKDMLREKGVRVVEHSADYSKAVEEGRKESDADPNSYFIDD
EHSIDLFVGYAVAAFRLKEQLQEKGIAVTKDQPLHVYLPCGVGGGPGGVAFGLKLVFGDAVRCFFAEPTHSPCMLIGMLT
GKHQHISVQDFGIDNQTAADGLAVGRPSGFVGRMMAPLLEGIYTIADPMLYTLLADLADAEGLYLEPSAVAGLYGPVQLE
KRGLYTDAATHLVWATGGSMVPKEIMETDYQLGVNLRTEQ

Sequences:

>Translated_440_residues
MDIAGKNREQWLAAYPLLQQIVLTKEVWWANPNRQPASEGLARLSLKEEDVKEAEQRLRRFAPYIASVFPETKGAGGLIE
SPLIDIPTMKHKLDQRFGQNVPGRLLLKGDHALPISGSIKARGGIYEVLKHAESLLVDQQILTKQDDYSLIATDAVQSFF
SSYAIVVGSTGNLGLSIGIISAKLGFRVTVHMSDDAKQWKKDMLREKGVRVVEHSADYSKAVEEGRKESDADPNSYFIDD
EHSIDLFVGYAVAAFRLKEQLQEKGIAVTKDQPLHVYLPCGVGGGPGGVAFGLKLVFGDAVRCFFAEPTHSPCMLIGMLT
GKHQHISVQDFGIDNQTAADGLAVGRPSGFVGRMMAPLLEGIYTIADPMLYTLLADLADAEGLYLEPSAVAGLYGPVQLE
KRGLYTDAATHLVWATGGSMVPKEIMETDYQLGVNLRTEQ
>Mature_440_residues
MDIAGKNREQWLAAYPLLQQIVLTKEVWWANPNRQPASEGLARLSLKEEDVKEAEQRLRRFAPYIASVFPETKGAGGLIE
SPLIDIPTMKHKLDQRFGQNVPGRLLLKGDHALPISGSIKARGGIYEVLKHAESLLVDQQILTKQDDYSLIATDAVQSFF
SSYAIVVGSTGNLGLSIGIISAKLGFRVTVHMSDDAKQWKKDMLREKGVRVVEHSADYSKAVEEGRKESDADPNSYFIDD
EHSIDLFVGYAVAAFRLKEQLQEKGIAVTKDQPLHVYLPCGVGGGPGGVAFGLKLVFGDAVRCFFAEPTHSPCMLIGMLT
GKHQHISVQDFGIDNQTAADGLAVGRPSGFVGRMMAPLLEGIYTIADPMLYTLLADLADAEGLYLEPSAVAGLYGPVQLE
KRGLYTDAATHLVWATGGSMVPKEIMETDYQLGVNLRTEQ

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=426, Percent_Identity=58.6854460093897, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_BACSK (Q5WGL6)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175450.1
- ProteinModelPortal:   Q5WGL6
- STRING:   Q5WGL6
- EnsemblBacteria:   EBBACT00000049557
- GeneID:   3202337
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1954
- NMPDR:   fig|66692.3.peg.32
- eggNOG:   COG3048
- GeneTree:   EBGT00050000001628
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- ProtClustDB:   PRK02991
- BioCyc:   BCLA66692:ABC1954-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 48074; Mature: 48074

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIAGKNREQWLAAYPLLQQIVLTKEVWWANPNRQPASEGLARLSLKEEDVKEAEQRLRR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
FAPYIASVFPETKGAGGLIESPLIDIPTMKHKLDQRFGQNVPGRLLLKGDHALPISGSIK
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
ARGGIYEVLKHAESLLVDQQILTKQDDYSLIATDAVQSFFSSYAIVVGSTGNLGLSIGII
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCEEEEEECCCCCEEEEEEE
SAKLGFRVTVHMSDDAKQWKKDMLREKGVRVVEHSADYSKAVEEGRKESDADPNSYFIDD
EECCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCCCCCCEEECC
EHSIDLFVGYAVAAFRLKEQLQEKGIAVTKDQPLHVYLPCGVGGGPGGVAFGLKLVFGDA
CCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
VRCFFAEPTHSPCMLIGMLTGKHQHISVQDFGIDNQTAADGLAVGRPSGFVGRMMAPLLE
EEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GIYTIADPMLYTLLADLADAEGLYLEPSAVAGLYGPVQLEKRGLYTDAATHLVWATGGSM
HHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCCCCEEECCCCCCCCHHHEEEEECCCCC
VPKEIMETDYQLGVNLRTEQ
CHHHHHCCCHHCCCEEECCC
>Mature Secondary Structure
MDIAGKNREQWLAAYPLLQQIVLTKEVWWANPNRQPASEGLARLSLKEEDVKEAEQRLRR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
FAPYIASVFPETKGAGGLIESPLIDIPTMKHKLDQRFGQNVPGRLLLKGDHALPISGSIK
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
ARGGIYEVLKHAESLLVDQQILTKQDDYSLIATDAVQSFFSSYAIVVGSTGNLGLSIGII
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCEEEEEECCCCCEEEEEEE
SAKLGFRVTVHMSDDAKQWKKDMLREKGVRVVEHSADYSKAVEEGRKESDADPNSYFIDD
EECCCEEEEEEECCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCCCCCCEEECC
EHSIDLFVGYAVAAFRLKEQLQEKGIAVTKDQPLHVYLPCGVGGGPGGVAFGLKLVFGDA
CCCEEHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
VRCFFAEPTHSPCMLIGMLTGKHQHISVQDFGIDNQTAADGLAVGRPSGFVGRMMAPLLE
EEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GIYTIADPMLYTLLADLADAEGLYLEPSAVAGLYGPVQLEKRGLYTDAATHLVWATGGSM
HHHHHHHHHHHHHHHHHCCCCCEEECCHHHHCCCCCEEECCCCCCCCHHHEEEEECCCCC
VPKEIMETDYQLGVNLRTEQ
CHHHHHCCCHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA