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The map label for this gene is asbF [H]

Identifier: 56963717

GI number: 56963717

Start: 2067891

End: 2068721

Strand: Direct

Name: asbF [H]

Synonym: ABC1952

Alternate gene names: 56963717

Gene position: 2067891-2068721 (Clockwise)

Preceding gene: 56963716

Following gene: 56963719

Centisome position: 48.05

GC content: 46.21

Gene sequence:

>831_bases
ATGAATGTGTCGATTTGTACCATTTCTTTTCGCCATGCATTAGTGTCGATCGACCAGCTTGCTGATTGGGCGAAGGCCCA
CGATGTCGATGGAATTGAATTGTGGGCCCCTCATGCCCGCCACTTGTTTGCCACTCCATCCTACAATGGCGACTGGCTTA
AAAAACAGGGCCTGATCGTACCAATGGTAAGTGATTACTTTCCGCTTTATGAGGAATGGAATACATTAATAGAGGCTGCC
AAACAGGCATCACGTCTATTGACGAGATGGAATACGAACCACATCCGCACATTTGCCGGTGCAAAGGGAAGCAAGGATAC
GACAAAAGCAGAACGAGCCTATCTTGTAAAACGGTTAGCTTGTCTTTGTGACTACTTTTTCGACAAAGGGCACTATGTGT
TGGTTGAAACACATCCCCATACGCTATGTGATACAGTCCCATCCACGCTGCAATTGTTGGCGGAAGTCGATCATCCAGGG
TTAGCAATCAATTTTGATGTCCTTCATGTATGGGAAAGCGGAGCGGATGTAAACGGTGCGTTTAAACAATTGCAGCCTCA
TATCCGCCATCTGCATGTAAAAAACATTCGCTCGCCAGAAGACTTAGATGTATTTGCGCCTGAAAATGTTTATGCTGCTG
CCGGATCTAGAGAGGGAATGGCCGGGCTGTTTAATGGATGCGTTGATTATGAGTCCTTTCTGTCAGCGAATCAATTGGAC
GGCGTCAATGTATCGATTGAATGGTTCGGGAACGAACCGTTTCACGTGTTAGAGCAAGACTGCCAGCAATTAATGAAATG
GAAAACAGTCCCCAATAGAGTGGTGCATTAG

Upstream 100 bases:

>100_bases
TGGAAAAACAAGATCTACGGGAAAGGCGAATCAAACACAGGCTATACGATTATTTTAGGGAATGGCAACAATTACAAGAA
ATGGCTAGGGGGGTGAACGC

Downstream 100 bases:

>100_bases
AAGAATTGCTTTAACGGGCCGCAGCTCTCTTTTGGGCAATGATCCATGGAACGGCGGCACGCAAGTCCGGGAAGCGTGCG
TCTGCTTGGAAATCGTCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: 3-DHS dehydratase; DHSase; Petrobactin biosynthesis protein AsbF [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNVSICTISFRHALVSIDQLADWAKAHDVDGIELWAPHARHLFATPSYNGDWLKKQGLIVPMVSDYFPLYEEWNTLIEAA
KQASRLLTRWNTNHIRTFAGAKGSKDTTKAERAYLVKRLACLCDYFFDKGHYVLVETHPHTLCDTVPSTLQLLAEVDHPG
LAINFDVLHVWESGADVNGAFKQLQPHIRHLHVKNIRSPEDLDVFAPENVYAAAGSREGMAGLFNGCVDYESFLSANQLD
GVNVSIEWFGNEPFHVLEQDCQQLMKWKTVPNRVVH

Sequences:

>Translated_276_residues
MNVSICTISFRHALVSIDQLADWAKAHDVDGIELWAPHARHLFATPSYNGDWLKKQGLIVPMVSDYFPLYEEWNTLIEAA
KQASRLLTRWNTNHIRTFAGAKGSKDTTKAERAYLVKRLACLCDYFFDKGHYVLVETHPHTLCDTVPSTLQLLAEVDHPG
LAINFDVLHVWESGADVNGAFKQLQPHIRHLHVKNIRSPEDLDVFAPENVYAAAGSREGMAGLFNGCVDYESFLSANQLD
GVNVSIEWFGNEPFHVLEQDCQQLMKWKTVPNRVVH
>Mature_276_residues
MNVSICTISFRHALVSIDQLADWAKAHDVDGIELWAPHARHLFATPSYNGDWLKKQGLIVPMVSDYFPLYEEWNTLIEAA
KQASRLLTRWNTNHIRTFAGAKGSKDTTKAERAYLVKRLACLCDYFFDKGHYVLVETHPHTLCDTVPSTLQLLAEVDHPG
LAINFDVLHVWESGADVNGAFKQLQPHIRHLHVKNIRSPEDLDVFAPENVYAAAGSREGMAGLFNGCVDYESFLSANQLD
GVNVSIEWFGNEPFHVLEQDCQQLMKWKTVPNRVVH

Specific function: Converts 3-dehydroshikimate to protocatechuate (3,4- dihydroxybenzoate), a biosynthetic unit required for the biosynthesis of petrobactin which is a virulence-associated siderophore produced by B.anthracis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.118 [H]

Molecular weight: Translated: 31224; Mature: 31224

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSICTISFRHALVSIDQLADWAKAHDVDGIELWAPHARHLFATPSYNGDWLKKQGLIV
CCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCHHHCCEEE
PMVSDYFPLYEEWNTLIEAAKQASRLLTRWNTNHIRTFAGAKGSKDTTKAERAYLVKRLA
EEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
CLCDYFFDKGHYVLVETHPHTLCDTVPSTLQLLAEVDHPGLAINFDVLHVWESGADVNGA
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCHH
FKQLQPHIRHLHVKNIRSPEDLDVFAPENVYAAAGSREGMAGLFNGCVDYESFLSANQLD
HHHHHHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GVNVSIEWFGNEPFHVLEQDCQQLMKWKTVPNRVVH
CCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MNVSICTISFRHALVSIDQLADWAKAHDVDGIELWAPHARHLFATPSYNGDWLKKQGLIV
CCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCCHHHCCEEE
PMVSDYFPLYEEWNTLIEAAKQASRLLTRWNTNHIRTFAGAKGSKDTTKAERAYLVKRLA
EEHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
CLCDYFFDKGHYVLVETHPHTLCDTVPSTLQLLAEVDHPGLAINFDVLHVWESGADVNGA
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCHH
FKQLQPHIRHLHVKNIRSPEDLDVFAPENVYAAAGSREGMAGLFNGCVDYESFLSANQLD
HHHHHHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GVNVSIEWFGNEPFHVLEQDCQQLMKWKTVPNRVVH
CCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]