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The map label for this gene is yqeV [H]

Identifier: 56963428

GI number: 56963428

Start: 1793238

End: 1794575

Strand: Direct

Name: yqeV [H]

Synonym: ABC1663

Alternate gene names: 56963428

Gene position: 1793238-1794575 (Clockwise)

Preceding gene: 56963427

Following gene: 56963429

Centisome position: 41.67

GC content: 45.29

Gene sequence:

>1338_bases
TTGTCAACTGTTGCGTTTCATACATTAGGCTGTAAAGTAAACCATTACGAGACGGAAGCGATTTGGCAGCTGTTTAAACA
AGAAGGCTATGAAAAAGTCGAGTTTGAACAGACTGCAGACGTCTATGTCATTAATACATGTACGGTCACCAATACAGGTG
ACAAAAAAAGCAGGCAAGTCATTCGCCGCGCGATTCGCAAAAACCCAGACGCTGTTATTTGCGTAACTGGCTGTTACGCG
CAAACGTCTCCTGCTGAAGTGATGGCCATTCCTGGGGTCGATATTGTTGTCGGTACGCAAGACCGCTCGAAAATGCTTGG
TTACATCGACCAATATAAAAAAGAGCGGCAGCCAATCAACGCTGTCGGCAATATTATGAAATCACGGGTATATGAAGAAT
TGGATGTGCCTTCATTTACGGATCGGACACGGGCGTCTTTAAAAATTCAAGAAGGCTGTAACAATTTCTGCACATTTTGC
ATTATTCCTTGGGCGCGAGGGTTGATGCGTTCCCGCGATCCACAAGAAGTCGTGCGCCAAGCCCAGCAACTTGTTCATGC
TGGCTACAAAGAAATCGTGTTGACTGGCATTCATACTGGCGGCTATGGCGAAGATTTGAAGGATTATAGCCTTGCCCGCT
TGTTAGAGGATTTGGAAAAGGTAGAGGGGCTGAAACGGCTTCGTATTTCGTCGATTGAGGCGAGCCAATTAACCGACGAG
GTCATTGCGGTGATCGGCAAATCAAGCAAAGTGGTCCGCCATATGCACATTCCGCTCCAATCTGGATCGGATACGGTGCT
GAAACGGATGCGCAGGAAGTATACGATGGCCGCTTATGAAGAACGGATTGAAAAGTTAAAACAAGCCCTTCCACGGCTTG
CGATTACGTCCGATGTCATTGTTGGGTTTCCTGGCGAGACAGAAGAAGAGTTCCAAGAAACATACGACTTTATCGCCAAA
CATAAGTTCAGTGAATTGCATGTCTTTCCTTATTCGATGCGCACAGGTACGCCAGCTGCTCGGATGACAGACCAAATCGA
TGAGGCCATAAAAAATGAACGTGTGCACCGCTTAATTGAACTGTCAAACCAATTAGCGAAAGAATATGCCTCAAGTTTTG
AGAATGAAGTGCTTGAAGTCATTCCAGAAGAGCGAGATAAAGACAACCCTGAAAGCGGCTTGTTTGTCGGCTATACAGAT
AACTATTTAAAAGTAAAACTAGAAGCTGATGAAACGATGATTGGAAAATTGGTGCGCGTAAAAATCAAAGAGGCGGGCTA
TCCATATAACCGTGGCGAATTCGTCCGCGTTTTAGAAGATTACAAGCAAATTGTGTAA

Upstream 100 bases:

>100_bases
TCTCTTGCAGCATAGGCCCTCGCATTGTCCGTACTGAAACGGCTGCTATGTACGTGTTAGCTGCTCTTTCGTACCAATTT
GAATTATGAGGTGAATCCAG

Downstream 100 bases:

>100_bases
AAAACGCATTCCGGAAAATTCCGGGATGCGTTTTTTTTATAGAGGGTGATCATTTATTCCGAATATCTTTCCCTACCAGC
GCGTTTTATACTAAAAGCAA

Product: 2-methylthioadenine synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSTVAFHTLGCKVNHYETEAIWQLFKQEGYEKVEFEQTADVYVINTCTVTNTGDKKSRQVIRRAIRKNPDAVICVTGCYA
QTSPAEVMAIPGVDIVVGTQDRSKMLGYIDQYKKERQPINAVGNIMKSRVYEELDVPSFTDRTRASLKIQEGCNNFCTFC
IIPWARGLMRSRDPQEVVRQAQQLVHAGYKEIVLTGIHTGGYGEDLKDYSLARLLEDLEKVEGLKRLRISSIEASQLTDE
VIAVIGKSSKVVRHMHIPLQSGSDTVLKRMRRKYTMAAYEERIEKLKQALPRLAITSDVIVGFPGETEEEFQETYDFIAK
HKFSELHVFPYSMRTGTPAARMTDQIDEAIKNERVHRLIELSNQLAKEYASSFENEVLEVIPEERDKDNPESGLFVGYTD
NYLKVKLEADETMIGKLVRVKIKEAGYPYNRGEFVRVLEDYKQIV

Sequences:

>Translated_445_residues
MSTVAFHTLGCKVNHYETEAIWQLFKQEGYEKVEFEQTADVYVINTCTVTNTGDKKSRQVIRRAIRKNPDAVICVTGCYA
QTSPAEVMAIPGVDIVVGTQDRSKMLGYIDQYKKERQPINAVGNIMKSRVYEELDVPSFTDRTRASLKIQEGCNNFCTFC
IIPWARGLMRSRDPQEVVRQAQQLVHAGYKEIVLTGIHTGGYGEDLKDYSLARLLEDLEKVEGLKRLRISSIEASQLTDE
VIAVIGKSSKVVRHMHIPLQSGSDTVLKRMRRKYTMAAYEERIEKLKQALPRLAITSDVIVGFPGETEEEFQETYDFIAK
HKFSELHVFPYSMRTGTPAARMTDQIDEAIKNERVHRLIELSNQLAKEYASSFENEVLEVIPEERDKDNPESGLFVGYTD
NYLKVKLEADETMIGKLVRVKIKEAGYPYNRGEFVRVLEDYKQIV
>Mature_444_residues
STVAFHTLGCKVNHYETEAIWQLFKQEGYEKVEFEQTADVYVINTCTVTNTGDKKSRQVIRRAIRKNPDAVICVTGCYAQ
TSPAEVMAIPGVDIVVGTQDRSKMLGYIDQYKKERQPINAVGNIMKSRVYEELDVPSFTDRTRASLKIQEGCNNFCTFCI
IPWARGLMRSRDPQEVVRQAQQLVHAGYKEIVLTGIHTGGYGEDLKDYSLARLLEDLEKVEGLKRLRISSIEASQLTDEV
IAVIGKSSKVVRHMHIPLQSGSDTVLKRMRRKYTMAAYEERIEKLKQALPRLAITSDVIVGFPGETEEEFQETYDFIAKH
KFSELHVFPYSMRTGTPAARMTDQIDEAIKNERVHRLIELSNQLAKEYASSFENEVLEVIPEERDKDNPESGLFVGYTDN
YLKVKLEADETMIGKLVRVKIKEAGYPYNRGEFVRVLEDYKQIV

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=438, Percent_Identity=28.7671232876712, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI28872784, Length=391, Percent_Identity=26.8542199488491, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI28872782, Length=391, Percent_Identity=26.8542199488491, Blast_Score=162, Evalue=8e-40,
Organism=Escherichia coli, GI1786882, Length=438, Percent_Identity=32.648401826484, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1787057, Length=376, Percent_Identity=32.7127659574468, Blast_Score=184, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17553146, Length=386, Percent_Identity=27.979274611399, Blast_Score=161, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71996771, Length=354, Percent_Identity=29.6610169491525, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21356207, Length=475, Percent_Identity=27.7894736842105, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19922432, Length=430, Percent_Identity=30.4651162790698, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 50806; Mature: 50675

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVAFHTLGCKVNHYETEAIWQLFKQEGYEKVEFEQTADVYVINTCTVTNTGDKKSRQV
CCCEEEEEECCEECCCHHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEECCCCCHHHHHH
IRRAIRKNPDAVICVTGCYAQTSPAEVMAIPGVDIVVGTQDRSKMLGYIDQYKKERQPIN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCHH
AVGNIMKSRVYEELDVPSFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPQEVVRQ
HHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
AQQLVHAGYKEIVLTGIHTGGYGEDLKDYSLARLLEDLEKVEGLKRLRISSIEASQLTDE
HHHHHHCCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VIAVIGKSSKVVRHMHIPLQSGSDTVLKRMRRKYTMAAYEERIEKLKQALPRLAITSDVI
HHHHHCCCHHEEHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEE
VGFPGETEEEFQETYDFIAKHKFSELHVFPYSMRTGTPAARMTDQIDEAIKNERVHRLIE
EECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSNQLAKEYASSFENEVLEVIPEERDKDNPESGLFVGYTDNYLKVKLEADETMIGKLVRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEEECCHHHHHHHHHE
KIKEAGYPYNRGEFVRVLEDYKQIV
EECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
STVAFHTLGCKVNHYETEAIWQLFKQEGYEKVEFEQTADVYVINTCTVTNTGDKKSRQV
CCEEEEEECCEECCCHHHHHHHHHHHCCCCEECCCCCCCEEEEEEEEECCCCCHHHHHH
IRRAIRKNPDAVICVTGCYAQTSPAEVMAIPGVDIVVGTQDRSKMLGYIDQYKKERQPIN
HHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCHH
AVGNIMKSRVYEELDVPSFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPQEVVRQ
HHHHHHHHHHHHHCCCCCCCCCHHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
AQQLVHAGYKEIVLTGIHTGGYGEDLKDYSLARLLEDLEKVEGLKRLRISSIEASQLTDE
HHHHHHCCHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VIAVIGKSSKVVRHMHIPLQSGSDTVLKRMRRKYTMAAYEERIEKLKQALPRLAITSDVI
HHHHHCCCHHEEHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEE
VGFPGETEEEFQETYDFIAKHKFSELHVFPYSMRTGTPAARMTDQIDEAIKNERVHRLIE
EECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSNQLAKEYASSFENEVLEVIPEERDKDNPESGLFVGYTDNYLKVKLEADETMIGKLVRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEEEECCHHHHHHHHHE
KIKEAGYPYNRGEFVRVLEDYKQIV
EECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]