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The map label for this gene is abgB [H]

Identifier: 56963380

GI number: 56963380

Start: 1742214

End: 1743386

Strand: Direct

Name: abgB [H]

Synonym: ABC1615

Alternate gene names: 56963380

Gene position: 1742214-1743386 (Clockwise)

Preceding gene: 56963376

Following gene: 56963381

Centisome position: 40.48

GC content: 46.8

Gene sequence:

>1173_bases
ATGAAAGAACAAATTAGTGAAAAACTGGAACAGCTTCGTTTAACATTTTGGGAAGTAAGCCAGCATATTGGCCACAATCC
AGAACTTGGACATGAAGAGTTTATTGCTTGCAAAACATTGACTGACTTATTAAAATCACATGGATTTACAGTAGAAGTGG
GAACATGCGGGTTAGAAACGGCTTTTACAGCGACATTTGACAGCGGCCAACCTGGGCCGAAAGTGGGCTTTATGGCTGAA
TATGATGCCCTCCCGCAAATTGGTCATGCTTGCGGCCATAATTTAATTGGCACGATGTCGGCTGCAGCGGCGATTGGTCT
CAGTGACGTTTTGCATAAAACAGGGGGCAAGATATATGTCTATGGCACACCAGCGGAAGAGACACGTGGAGCGAAAGTGA
CCATGGCAGACGCAGGATTGTTTGATGATCTTGACGTAGCCATGATGGTCCATCCGAATGCCCATTATGAGGAAAGCGGA
ACTTCGTTGGCAATGGACGCCATTCAGTTCGACTTTTTTGGAAAGGCGGCCCATGCAGCGGCTAGCCCCCATGAGGGAAT
CAATGCATTGGATGCAGTCATAGCGACATTTAACCAAATCAATGCACTTAGGCAGCATGTTACGCCAGATGTGCGTATAC
ATGGCATTATCCCAGAAGGGGGACAGGCTGCAAATGTCGTTCCCGATTTTGCCAGAGCACAATTTTATGTGCGCGCTGCA
TCACGAAAAACGCTTCAACCTTTGCTTGAAAAGGTGAAAAACTGTGCGAAGGCAGCAGCTCTTGCGACTGGCGCACAGTT
GGAAATTTCGTTCTACGAGTTTTCCTATGACGATATGAATACAAATGAAGCGCTATCCAAACAATTTACCGCTAATTTGG
TTGCGTTGGGCGTTGACGTCGACGATATTCGCGAAAAAACACTTGGAGGCTCGTTGGATATGGGCAATGTCAGCCAGCGC
GTGCCCGCCATCCATCCGTACGTGAAAATTACAGATGGCGGTTATGCGTGCCATACGCCTGAATTCCGTGATGCCGCATT
AAGCGAGCAAGGATTTGAAGGGCTGATGCTTGGCGCAAAAACGATGGCGCATACGGCCTTTGATGTGTTGACTGATCAAG
CGCTTCTAGAAACAATTAAACAAGAATATAAAACGTGGAAAGAAAAACAGTAA

Upstream 100 bases:

>100_bases
AAATATTCATATGAATTTATATTTAACTTTATTTTAATATAAAGTATAATAGATAAATGTCAAGTAGCGAATAAAGATAC
GATGAATCGAGGAGAACCAA

Downstream 100 bases:

>100_bases
GAGAGCGTTCGAAAGGAGAAGCGCTATGCTAGAAGCAATGAGCCTCATCAAACGGCGAGTACGAGAGGAAAATAAAAAGA
CGAGAACAAAGCGATGAACC

Product: N-acyl-L-amino acid amidohydrolase

Products: carboxylate; L-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKEQISEKLEQLRLTFWEVSQHIGHNPELGHEEFIACKTLTDLLKSHGFTVEVGTCGLETAFTATFDSGQPGPKVGFMAE
YDALPQIGHACGHNLIGTMSAAAAIGLSDVLHKTGGKIYVYGTPAEETRGAKVTMADAGLFDDLDVAMMVHPNAHYEESG
TSLAMDAIQFDFFGKAAHAAASPHEGINALDAVIATFNQINALRQHVTPDVRIHGIIPEGGQAANVVPDFARAQFYVRAA
SRKTLQPLLEKVKNCAKAAALATGAQLEISFYEFSYDDMNTNEALSKQFTANLVALGVDVDDIREKTLGGSLDMGNVSQR
VPAIHPYVKITDGGYACHTPEFRDAALSEQGFEGLMLGAKTMAHTAFDVLTDQALLETIKQEYKTWKEKQ

Sequences:

>Translated_390_residues
MKEQISEKLEQLRLTFWEVSQHIGHNPELGHEEFIACKTLTDLLKSHGFTVEVGTCGLETAFTATFDSGQPGPKVGFMAE
YDALPQIGHACGHNLIGTMSAAAAIGLSDVLHKTGGKIYVYGTPAEETRGAKVTMADAGLFDDLDVAMMVHPNAHYEESG
TSLAMDAIQFDFFGKAAHAAASPHEGINALDAVIATFNQINALRQHVTPDVRIHGIIPEGGQAANVVPDFARAQFYVRAA
SRKTLQPLLEKVKNCAKAAALATGAQLEISFYEFSYDDMNTNEALSKQFTANLVALGVDVDDIREKTLGGSLDMGNVSQR
VPAIHPYVKITDGGYACHTPEFRDAALSEQGFEGLMLGAKTMAHTAFDVLTDQALLETIKQEYKTWKEKQ
>Mature_390_residues
MKEQISEKLEQLRLTFWEVSQHIGHNPELGHEEFIACKTLTDLLKSHGFTVEVGTCGLETAFTATFDSGQPGPKVGFMAE
YDALPQIGHACGHNLIGTMSAAAAIGLSDVLHKTGGKIYVYGTPAEETRGAKVTMADAGLFDDLDVAMMVHPNAHYEESG
TSLAMDAIQFDFFGKAAHAAASPHEGINALDAVIATFNQINALRQHVTPDVRIHGIIPEGGQAANVVPDFARAQFYVRAA
SRKTLQPLLEKVKNCAKAAALATGAQLEISFYEFSYDDMNTNEALSKQFTANLVALGVDVDDIREKTLGGSLDMGNVSQR
VPAIHPYVKITDGGYACHTPEFRDAALSEQGFEGLMLGAKTMAHTAFDVLTDQALLETIKQEYKTWKEKQ

Specific function: Required but not essential for aminobenzoyl-glutamate utilization. May participate in hydrolysis of aminobenzoyl- glutamate to aminobenzoate, either alone or in combination with AbgA [H]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI58082085, Length=386, Percent_Identity=38.0829015544041, Blast_Score=237, Evalue=2e-62,
Organism=Escherichia coli, GI1787598, Length=460, Percent_Identity=30.2173913043478, Blast_Score=164, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017145
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.5.1.14

Molecular weight: Translated: 42219; Mature: 42219

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQISEKLEQLRLTFWEVSQHIGHNPELGHEEFIACKTLTDLLKSHGFTVEVGTCGLET
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
AFTATFDSGQPGPKVGFMAEYDALPQIGHACGHNLIGTMSAAAAIGLSDVLHKTGGKIYV
EEEEEECCCCCCCCCCCEECHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
YGTPAEETRGAKVTMADAGLFDDLDVAMMVHPNAHYEESGTSLAMDAIQFDFFGKAAHAA
EECCHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHCCHHHHHC
ASPHEGINALDAVIATFNQINALRQHVTPDVRIHGIIPEGGQAANVVPDFARAQFYVRAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
SRKTLQPLLEKVKNCAKAAALATGAQLEISFYEFSYDDMNTNEALSKQFTANLVALGVDV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHCEEEEECCCH
DDIREKTLGGSLDMGNVSQRVPAIHPYVKITDGGYACHTPEFRDAALSEQGFEGLMLGAK
HHHHHHHCCCCCCCCCHHHCCCCCCCEEEEECCCEEECCCCHHHHHHHHCCCCHHHHHHH
TMAHTAFDVLTDQALLETIKQEYKTWKEKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEQISEKLEQLRLTFWEVSQHIGHNPELGHEEFIACKTLTDLLKSHGFTVEVGTCGLET
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
AFTATFDSGQPGPKVGFMAEYDALPQIGHACGHNLIGTMSAAAAIGLSDVLHKTGGKIYV
EEEEEECCCCCCCCCCCEECHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
YGTPAEETRGAKVTMADAGLFDDLDVAMMVHPNAHYEESGTSLAMDAIQFDFFGKAAHAA
EECCHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEHHHHHHHHCCHHHHHC
ASPHEGINALDAVIATFNQINALRQHVTPDVRIHGIIPEGGQAANVVPDFARAQFYVRAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
SRKTLQPLLEKVKNCAKAAALATGAQLEISFYEFSYDDMNTNEALSKQFTANLVALGVDV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHCEEEEECCCH
DDIREKTLGGSLDMGNVSQRVPAIHPYVKITDGGYACHTPEFRDAALSEQGFEGLMLGAK
HHHHHHHCCCCCCCCCHHHCCCCCCCEEEEECCCEEECCCCHHHHHHHHCCCCHHHHHHH
TMAHTAFDVLTDQALLETIKQEYKTWKEKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-acyl-L-amino acid; H2O

Specific reaction: An N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9829935 [H]