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The map label for this gene is treA [H]

Identifier: 56963036

GI number: 56963036

Start: 1384958

End: 1386628

Strand: Direct

Name: treA [H]

Synonym: ABC1264

Alternate gene names: 56963036

Gene position: 1384958-1386628 (Clockwise)

Preceding gene: 56963035

Following gene: 56963037

Centisome position: 32.18

GC content: 43.51

Gene sequence:

>1671_bases
ATGGAATGGTGGAGAACAAGTACGGTTTATCAAATTTACCCTAAAAGCTTTAACGATACGACTGGAAATGGCATTGGCGA
TTTGCAAGGGATCATTGAAAAGCTAGACTATTTAAAAGAACTAGGCATCGACGTCATTTGGTTAACGCCGATTTATGCTT
CCCCGCAAAATGACAATGGCTATGACATTTCCGATTATTATGCGATCCACGAAGACTATGGGACGATGGCCGACTTTGAA
GAACTCCTTAATGAAACCCATAAACGGGGAATGAAGCTAATTATGGACTTGGTTGTCAACCATACGTCGACTGAACATCA
ATGGTTTAAAAATGCGAAGCTAAGCAAACAAGCGAAGTACCGTGATTTTTATATTTGGAAAGAAGGCAAAGAAGGAGGTG
CACCAACAAATTGGCAATCGAAGTTTGGCGGTTCTGCGTGGGAATACAATGAAGCAACGGATGATTACTACTTGCATTTG
TTTGATGTCACGCAAGCAGACTTAAACTGGGAAAATGAACAACTGCGCAAGCATGTCTACGAGATGATGCATTTTTGGTT
TAATAAAGGCATTGATGGCTTCCGTCTTGATGTCATTAACTTAATATCGAAAGACCAACGCTTCCCTGACGATGATGGTT
CAGTTGCGCCAGGGGACGGCCGCAAATTTTACACAGATGGCCCCCGTGTCCATGAATACTTGCAGGAAATGAACCGAGAA
GTATTAGCCAAGTATGATAGCTTAACCGTTGGCGAAATGTCTTCAACGACGATTGAAGACTGTATACGCTATTCCAATCC
AAAACAGCGTGAACTATCAATGACGTTTAATTTCCACCATTTAAAAGTGGATTATCCAAATGGAGAAAAATGGGCTGTCG
CTGATTTTGATTTTAAAGCGCTAAAACAGATTTTATCGGAATGGCAAGTCCGTATGCATGAAGGCGGGGGATGGAATGCG
TTGTTTTGGTGCAACCACGACCAGCCGCGGGTTGTTAGCCGTTATGGCGATGAGGACGAATACCATAACCAATCAGCGAA
GATGTTGGCTGCGACCATCCATTTCATGCAAGGGACGCCCTATGTGTATCAGGGTGAAGAGTTCGGCATGACAAACCCGA
ATTTCACAAGCATCGACGATTACCGCGACGTAGAGTCATTGAATGTGTACGCTCGCTTAAAAGAAGAGGGTGTGCCTGAA
GAACATATTCTCGCGATCCTTAAACAGAAATCCCGGGACAACTCTCGGACGCCGGTCCAATGGGATTCAAGCGAGCAAGC
TGGATTTACAACGGGCACGCCATGGATAAAGGTGAGCAGCAATTACAAGGAGATCAATGCCAAAAAAGCGCTCAGTGACC
CGAATTCGATTTTTTATTTCTATCAAAAGCTCATTGCGCTGCGGAAAAAGCTGCCAATTGTGACAACAGGTGATTACCGC
TTGCTCGTGCCTGAACATGACCATGTATTTGCATACGTGCGCACGGATGGTACGGAAAAACTCCTTGTCGTTTCAAATTT
TTACCCTGTAAATTGCGATTTTGAATGCCCAGAAGATCTGGTATCATTAAAAGCGACACAGTTAATAAGCAACTACAACC
AAAAACGAAAACTGGAAAAAACATTTTCGCTCAAGCCTTATGAAACGGTAGCATTCCAGTTGAAGGAGTAA

Upstream 100 bases:

>100_bases
CATTCTCAAGGAACTGCTAAGCAGTTCCTTTTTTGAACTTGTATATACAAGTGTGCTAAACTGGTGGTAAATAGAGACAG
AGAAAGGTGGATAAACACAA

Downstream 100 bases:

>100_bases
GAGAAGCACGTGAAAAACAAGTTTCAATCGATTTATCAAGCGCTCATACAAGCAATCAATAGCGGTGTTTATGCTCCTGG
CGAAACGTTGCCTTCTGAAA

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MEWWRTSTVYQIYPKSFNDTTGNGIGDLQGIIEKLDYLKELGIDVIWLTPIYASPQNDNGYDISDYYAIHEDYGTMADFE
ELLNETHKRGMKLIMDLVVNHTSTEHQWFKNAKLSKQAKYRDFYIWKEGKEGGAPTNWQSKFGGSAWEYNEATDDYYLHL
FDVTQADLNWENEQLRKHVYEMMHFWFNKGIDGFRLDVINLISKDQRFPDDDGSVAPGDGRKFYTDGPRVHEYLQEMNRE
VLAKYDSLTVGEMSSTTIEDCIRYSNPKQRELSMTFNFHHLKVDYPNGEKWAVADFDFKALKQILSEWQVRMHEGGGWNA
LFWCNHDQPRVVSRYGDEDEYHNQSAKMLAATIHFMQGTPYVYQGEEFGMTNPNFTSIDDYRDVESLNVYARLKEEGVPE
EHILAILKQKSRDNSRTPVQWDSSEQAGFTTGTPWIKVSSNYKEINAKKALSDPNSIFYFYQKLIALRKKLPIVTTGDYR
LLVPEHDHVFAYVRTDGTEKLLVVSNFYPVNCDFECPEDLVSLKATQLISNYNQKRKLEKTFSLKPYETVAFQLKE

Sequences:

>Translated_556_residues
MEWWRTSTVYQIYPKSFNDTTGNGIGDLQGIIEKLDYLKELGIDVIWLTPIYASPQNDNGYDISDYYAIHEDYGTMADFE
ELLNETHKRGMKLIMDLVVNHTSTEHQWFKNAKLSKQAKYRDFYIWKEGKEGGAPTNWQSKFGGSAWEYNEATDDYYLHL
FDVTQADLNWENEQLRKHVYEMMHFWFNKGIDGFRLDVINLISKDQRFPDDDGSVAPGDGRKFYTDGPRVHEYLQEMNRE
VLAKYDSLTVGEMSSTTIEDCIRYSNPKQRELSMTFNFHHLKVDYPNGEKWAVADFDFKALKQILSEWQVRMHEGGGWNA
LFWCNHDQPRVVSRYGDEDEYHNQSAKMLAATIHFMQGTPYVYQGEEFGMTNPNFTSIDDYRDVESLNVYARLKEEGVPE
EHILAILKQKSRDNSRTPVQWDSSEQAGFTTGTPWIKVSSNYKEINAKKALSDPNSIFYFYQKLIALRKKLPIVTTGDYR
LLVPEHDHVFAYVRTDGTEKLLVVSNFYPVNCDFECPEDLVSLKATQLISNYNQKRKLEKTFSLKPYETVAFQLKE
>Mature_556_residues
MEWWRTSTVYQIYPKSFNDTTGNGIGDLQGIIEKLDYLKELGIDVIWLTPIYASPQNDNGYDISDYYAIHEDYGTMADFE
ELLNETHKRGMKLIMDLVVNHTSTEHQWFKNAKLSKQAKYRDFYIWKEGKEGGAPTNWQSKFGGSAWEYNEATDDYYLHL
FDVTQADLNWENEQLRKHVYEMMHFWFNKGIDGFRLDVINLISKDQRFPDDDGSVAPGDGRKFYTDGPRVHEYLQEMNRE
VLAKYDSLTVGEMSSTTIEDCIRYSNPKQRELSMTFNFHHLKVDYPNGEKWAVADFDFKALKQILSEWQVRMHEGGGWNA
LFWCNHDQPRVVSRYGDEDEYHNQSAKMLAATIHFMQGTPYVYQGEEFGMTNPNFTSIDDYRDVESLNVYARLKEEGVPE
EHILAILKQKSRDNSRTPVQWDSSEQAGFTTGTPWIKVSSNYKEINAKKALSDPNSIFYFYQKLIALRKKLPIVTTGDYR
LLVPEHDHVFAYVRTDGTEKLLVVSNFYPVNCDFECPEDLVSLKATQLISNYNQKRKLEKTFSLKPYETVAFQLKE

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=530, Percent_Identity=28.3018867924528, Blast_Score=231, Evalue=1e-60,
Organism=Escherichia coli, GI1790687, Length=555, Percent_Identity=54.0540540540541, Blast_Score=632, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=192, Percent_Identity=26.5625, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147709, Length=584, Percent_Identity=25, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32565753, Length=383, Percent_Identity=24.8041775456919, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322245, Length=578, Percent_Identity=38.7543252595156, Blast_Score=398, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321726, Length=572, Percent_Identity=38.1118881118881, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6324416, Length=574, Percent_Identity=37.9790940766551, Blast_Score=369, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6322241, Length=572, Percent_Identity=37.9370629370629, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6322021, Length=572, Percent_Identity=37.9370629370629, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6321731, Length=579, Percent_Identity=35.5785837651123, Blast_Score=340, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6319776, Length=579, Percent_Identity=35.405872193437, Blast_Score=339, Evalue=6e-94,
Organism=Drosophila melanogaster, GI221330053, Length=502, Percent_Identity=36.0557768924303, Blast_Score=296, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24583745, Length=586, Percent_Identity=35.6655290102389, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24583747, Length=530, Percent_Identity=34.7169811320755, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24583749, Length=530, Percent_Identity=34.7169811320755, Blast_Score=280, Evalue=3e-75,
Organism=Drosophila melanogaster, GI45549022, Length=538, Percent_Identity=33.8289962825279, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24586599, Length=587, Percent_Identity=31.0051107325383, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24586597, Length=536, Percent_Identity=32.8358208955224, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24586593, Length=504, Percent_Identity=33.7301587301587, Blast_Score=265, Evalue=7e-71,
Organism=Drosophila melanogaster, GI24586591, Length=590, Percent_Identity=32.0338983050847, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24586589, Length=586, Percent_Identity=32.5938566552901, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24586587, Length=589, Percent_Identity=30.5602716468591, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI281360393, Length=447, Percent_Identity=30.6487695749441, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 64909; Mature: 64909

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWWRTSTVYQIYPKSFNDTTGNGIGDLQGIIEKLDYLKELGIDVIWLTPIYASPQNDNG
CCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
YDISDYYAIHEDYGTMADFEELLNETHKRGMKLIMDLVVNHTSTEHQWFKNAKLSKQAKY
CCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCC
RDFYIWKEGKEGGAPTNWQSKFGGSAWEYNEATDDYYLHLFDVTQADLNWENEQLRKHVY
CEEEEEECCCCCCCCCCCHHHCCCCCEECCCCCCCEEEEEEEEEECCCCCCHHHHHHHHH
EMMHFWFNKGIDGFRLDVINLISKDQRFPDDDGSVAPGDGRKFYTDGPRVHEYLQEMNRE
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
VLAKYDSLTVGEMSSTTIEDCIRYSNPKQRELSMTFNFHHLKVDYPNGEKWAVADFDFKA
HHHHHCCCEECCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEEEECCCCCEEEEECCCHHH
LKQILSEWQVRMHEGGGWNALFWCNHDQPRVVSRYGDEDEYHNQSAKMLAATIHFMQGTP
HHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHCCCCHHHHCHHHHHHHHHHHHHCCCC
YVYQGEEFGMTNPNFTSIDDYRDVESLNVYARLKEEGVPEEHILAILKQKSRDNSRTPVQ
EEEECCCCCCCCCCCCCCCCCCCHHHHHHEEEEHHCCCCHHHHHHHHHHHCCCCCCCCEE
WDSSEQAGFTTGTPWIKVSSNYKEINAKKALSDPNSIFYFYQKLIALRKKLPIVTTGDYR
ECCCCCCCCCCCCCEEEECCCCHHHCHHHHCCCCHHHHHHHHHHHHHHHCCCEEECCCEE
LLVPEHDHVFAYVRTDGTEKLLVVSNFYPVNCDFECPEDLVSLKATQLISNYNQKRKLEK
EEECCCCCEEEEEEECCCCEEEEEECEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
TFSLKPYETVAFQLKE
HCCCCCCEEEEEEECC
>Mature Secondary Structure
MEWWRTSTVYQIYPKSFNDTTGNGIGDLQGIIEKLDYLKELGIDVIWLTPIYASPQNDNG
CCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
YDISDYYAIHEDYGTMADFEELLNETHKRGMKLIMDLVVNHTSTEHQWFKNAKLSKQAKY
CCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCC
RDFYIWKEGKEGGAPTNWQSKFGGSAWEYNEATDDYYLHLFDVTQADLNWENEQLRKHVY
CEEEEEECCCCCCCCCCCHHHCCCCCEECCCCCCCEEEEEEEEEECCCCCCHHHHHHHHH
EMMHFWFNKGIDGFRLDVINLISKDQRFPDDDGSVAPGDGRKFYTDGPRVHEYLQEMNRE
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
VLAKYDSLTVGEMSSTTIEDCIRYSNPKQRELSMTFNFHHLKVDYPNGEKWAVADFDFKA
HHHHHCCCEECCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEEEECCCCCEEEEECCCHHH
LKQILSEWQVRMHEGGGWNALFWCNHDQPRVVSRYGDEDEYHNQSAKMLAATIHFMQGTP
HHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHCCCCHHHHCHHHHHHHHHHHHHCCCC
YVYQGEEFGMTNPNFTSIDDYRDVESLNVYARLKEEGVPEEHILAILKQKSRDNSRTPVQ
EEEECCCCCCCCCCCCCCCCCCCHHHHHHEEEEHHCCCCHHHHHHHHHHHCCCCCCCCEE
WDSSEQAGFTTGTPWIKVSSNYKEINAKKALSDPNSIFYFYQKLIALRKKLPIVTTGDYR
ECCCCCCCCCCCCCEEEECCCCHHHCHHHHCCCCHHHHHHHHHHHHHHHCCCEEECCCEE
LLVPEHDHVFAYVRTDGTEKLLVVSNFYPVNCDFECPEDLVSLKATQLISNYNQKRKLEK
EEECCCCCEEEEEEECCCCEEEEEECEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
TFSLKPYETVAFQLKE
HCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]