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The map label for this gene is aroC [H]

Identifier: 55981353

GI number: 55981353

Start: 1320847

End: 1321998

Strand: Direct

Name: aroC [H]

Synonym: TTHA1384

Alternate gene names: 55981353

Gene position: 1320847-1321998 (Clockwise)

Preceding gene: 55981352

Following gene: 55981354

Centisome position: 71.41

GC content: 70.66

Gene sequence:

>1152_bases
ATGCGGTTTCTCACGGCAGGCGAGTCCCACGGGCCCGAGCTTCTCGCCATCATTGAAGGGCTTCCCGCCGGGCTTCCCCT
CAGCGAGGAGGACATCAACCCCTGGCTGGAGAAGCGGCAGAAGGGCTACGGCCGGGGCCGGCGCATGGTCATTGAGCGCG
ACCGGGTGGAGTTCCGCGCCGGGGTGAGGGGCGGGCGCACCACGGGCGCCCCCGTGGCCCTGGCCATCAAGAACGCCGAC
TTCAAGAACTGGGCCGAGATCATGGACCCCGCCCCGGGGAACTGGCCCAGGAAACGGGCCCTGACCGCGGCCAGGCCGGG
CCACGCCGACCTCGCCGGGGGCATGAAGTACGGGCACAAGGACCTGAGGGACGTGCTAGAAAGGGCGAGCGCCCGGGAGA
CGGCCATGCGGGTGGCCGTGGGGGCCGTGGCCCTGAAGCTCCTCTCCCTCCTCGGGGTGGAGGGGGTGGGGTACGTCCCG
GGGATGGCGGGGGTGTGGGCCAAGGTGCCCTTCTCTTGGGACCTGGTGCCCCGCATTGAGGAAAGCCCCCTGCGCATGAC
CGACCCCGAGGCGGAGGCCGAGGCGATCCGCCGCATTGACCAGGCCAAGGCCGAGGGGGACACCCTGGGCGGGATCATTG
AGGCCCGCTTCCGGGGGCTCGTGCCGGGGCTTGGGAGCCACGTCCACTGGGACCGGAAGCTGGACGGGAGGCTGGCCCAG
ATGGCCCTCTCCATCCCGGCGGTGAAGGGGGTGGAGATCGGCCCCGCCTTTGAAAACGCCATGAAGCGGGGCTCCGAGGT
GCACGACGCCATCTACTGGAGCCCGGAGCGGGGCTTCTACCGGAAGACCAACCGGGCAGGGGGGCTGGAAGGGGGCATGA
CCACGGGGGAGGAGCTCGTGGTCCGGGCCGCCCTCAAGCCCATCGCCACCCTGATGAAGCCCCTTCCCACCGTGGACGTG
GTGACCCACGAGCCCAAGGACGCCGCCAGGGAGAGAAGCGACACCACGGCGGTGCCCGCGGCGAGCGTCATCCTCTGCGC
CCTCTCGGCCATCGTCCTGGCCCAGGCCTACCTGGAGAAGTTCGGGGGGGACACCATGGAGGAGATCCAGGAACGGGTGG
AGCGCTACCGGGAGCGGGTGCGGGCCTACTGA

Upstream 100 bases:

>100_bases
ACCGCCGACATCCTCAAGGAGACGGCCTCGGCGAACCCCTAAGAGGCCGGGCGTTCCGCAAGGGGGGCCCGTGGGCCCCC
CTTTGGCCTACAATGTCCCC

Downstream 100 bases:

>100_bases
GCCCGGCCCAGGTAGGATGGGAGGATGGCCCGCCTCGAGGTTCCCCGTCCCGCCACCTTCGTCACCCTCACCGGGTTCAT
GGGGGTGGGGAAAAGCCGCA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRFLTAGESHGPELLAIIEGLPAGLPLSEEDINPWLEKRQKGYGRGRRMVIERDRVEFRAGVRGGRTTGAPVALAIKNAD
FKNWAEIMDPAPGNWPRKRALTAARPGHADLAGGMKYGHKDLRDVLERASARETAMRVAVGAVALKLLSLLGVEGVGYVP
GMAGVWAKVPFSWDLVPRIEESPLRMTDPEAEAEAIRRIDQAKAEGDTLGGIIEARFRGLVPGLGSHVHWDRKLDGRLAQ
MALSIPAVKGVEIGPAFENAMKRGSEVHDAIYWSPERGFYRKTNRAGGLEGGMTTGEELVVRAALKPIATLMKPLPTVDV
VTHEPKDAARERSDTTAVPAASVILCALSAIVLAQAYLEKFGGDTMEEIQERVERYRERVRAY

Sequences:

>Translated_383_residues
MRFLTAGESHGPELLAIIEGLPAGLPLSEEDINPWLEKRQKGYGRGRRMVIERDRVEFRAGVRGGRTTGAPVALAIKNAD
FKNWAEIMDPAPGNWPRKRALTAARPGHADLAGGMKYGHKDLRDVLERASARETAMRVAVGAVALKLLSLLGVEGVGYVP
GMAGVWAKVPFSWDLVPRIEESPLRMTDPEAEAEAIRRIDQAKAEGDTLGGIIEARFRGLVPGLGSHVHWDRKLDGRLAQ
MALSIPAVKGVEIGPAFENAMKRGSEVHDAIYWSPERGFYRKTNRAGGLEGGMTTGEELVVRAALKPIATLMKPLPTVDV
VTHEPKDAARERSDTTAVPAASVILCALSAIVLAQAYLEKFGGDTMEEIQERVERYRERVRAY
>Mature_383_residues
MRFLTAGESHGPELLAIIEGLPAGLPLSEEDINPWLEKRQKGYGRGRRMVIERDRVEFRAGVRGGRTTGAPVALAIKNAD
FKNWAEIMDPAPGNWPRKRALTAARPGHADLAGGMKYGHKDLRDVLERASARETAMRVAVGAVALKLLSLLGVEGVGYVP
GMAGVWAKVPFSWDLVPRIEESPLRMTDPEAEAEAIRRIDQAKAEGDTLGGIIEARFRGLVPGLGSHVHWDRKLDGRLAQ
MALSIPAVKGVEIGPAFENAMKRGSEVHDAIYWSPERGFYRKTNRAGGLEGGMTTGEELVVRAALKPIATLMKPLPTVDV
VTHEPKDAARERSDTTAVPAASVILCALSAIVLAQAYLEKFGGDTMEEIQERVERYRERVRAY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=35.7142857142857, Blast_Score=153, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321290, Length=372, Percent_Identity=34.6774193548387, Blast_Score=174, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 41823; Mature: 41823

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00788 CHORISMATE_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLTAGESHGPELLAIIEGLPAGLPLSEEDINPWLEKRQKGYGRGRRMVIERDRVEFRA
CCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCCCEEEEEHHHHHHHH
GVRGGRTTGAPVALAIKNADFKNWAEIMDPAPGNWPRKRALTAARPGHADLAGGMKYGHK
CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHCCHHCCHH
DLRDVLERASARETAMRVAVGAVALKLLSLLGVEGVGYVPGMAGVWAKVPFSWDLVPRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCCCCCCC
ESPLRMTDPEAEAEAIRRIDQAKAEGDTLGGIIEARFRGLVPGLGSHVHWDRKLDGRLAQ
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
MALSIPAVKGVEIGPAFENAMKRGSEVHDAIYWSPERGFYRKTNRAGGLEGGMTTGEELV
HHHHCCCCCCCCCCHHHHHHHHCCCHHHHHEEECCCCCCHHHCCCCCCCCCCCCCHHHHH
VRAALKPIATLMKPLPTVDVVTHEPKDAARERSDTTAVPAASVILCALSAIVLAQAYLEK
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGGDTMEEIQERVERYRERVRAY
HCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFLTAGESHGPELLAIIEGLPAGLPLSEEDINPWLEKRQKGYGRGRRMVIERDRVEFRA
CCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCCCEEEEEHHHHHHHH
GVRGGRTTGAPVALAIKNADFKNWAEIMDPAPGNWPRKRALTAARPGHADLAGGMKYGHK
CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHCCHHCCHH
DLRDVLERASARETAMRVAVGAVALKLLSLLGVEGVGYVPGMAGVWAKVPFSWDLVPRIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCCCCCCC
ESPLRMTDPEAEAEAIRRIDQAKAEGDTLGGIIEARFRGLVPGLGSHVHWDRKLDGRLAQ
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
MALSIPAVKGVEIGPAFENAMKRGSEVHDAIYWSPERGFYRKTNRAGGLEGGMTTGEELV
HHHHCCCCCCCCCCHHHHHHHHCCCHHHHHEEECCCCCCHHHCCCCCCCCCCCCCHHHHH
VRAALKPIATLMKPLPTVDVVTHEPKDAARERSDTTAVPAASVILCALSAIVLAQAYLEK
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGGDTMEEIQERVERYRERVRAY
HCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA