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The map label for this gene is nadA [H]

Identifier: 55980953

GI number: 55980953

Start: 927346

End: 928278

Strand: Reverse

Name: nadA [H]

Synonym: TTHA0984

Alternate gene names: 55980953

Gene position: 928278-927346 (Counterclockwise)

Preceding gene: 55980954

Following gene: 55980952

Centisome position: 50.18

GC content: 68.81

Gene sequence:

>933_bases
ATGGGTAGGATGCGTGGGGAAGCCCTGGCGCAAGAGGTCCTCAGGCTCAAGCGGGAGCGGAACGCCGTCATCCTGGCCCA
CTCCTACCAGCTCCCCGAGGTGCAGGAGGTGGCGGACTTCGTGGGGGACTCCCTGGGCCTCGCCCGAGAGGCCCAAAGAA
CGCGGGCCGAGGTCATCGTCTTCTGCGGCGTCCATTTCATGGCGGAGACCGCCGCCATCCTGAACCCCGAGAAGACGGTG
CTTCTGCCCGACCTGGAGGCGGGCTGCTCCCTCGCCGACAGCATCCGGCCCGAGGACGTCCTGGCCTGGAAGGCAAAGCA
CCCCGACGGGATCGTGGTGGCCTACGTGAACACCAAGGCGGAGGTCAAGGCCCTGGCGGACGTCTGCGTGACGAGCGCGA
ACGCCGTGGAGGTGGTCTCCCGGCTTCCCCAGGACCGGCCCATCTACTTCGTCCCCGACATGTTCCTGGGGGCCCACGTG
GCCCGGGTCACGGGGAGGAGGCTGGACCTCTTCCCCGGGGAGTGCCACGTGCACGCGGGGATCCGGGAGGAGCACCTGAA
GGCCCTCCTGGAAGCCCACCCGGGGGCGGAGTTCCTCATCCACCCGGAGTGCGGCTGCGGCAGCGGGTGCCTCTACCTCA
AGCCCGACGCCAAGATGCTCTCCACGGAGGGGATGGTGCGCTACGCCAAGGGGGCGGAGGCCCGGGAGTTCGTGGTGGCC
ACGGAGGTGGGGATCCTCCATCGCCTCAAGAAGGAGGCCCCGGAAAAAGCCTTCTTCCCGGTGAAGCCCGACGCCGTGTG
CGAGTACATGAAGCGGATCACCCTGGAGAAGGTCTACCTCTCCTTGAAGGAGATGCGCCACGTGGTCCGGGTGCCCGAGG
AGGTGGCGGGGAGGGCGCGCCGGGCCCTCGAGGCCATGGTGGCCGTGGGGTGA

Upstream 100 bases:

>100_bases
CACTCGGCCAAGGCCCTGGACCTCTCCCTCCTGGTGGTGCGTCCATGAGGGCGTGGAGGCGGTTCGGGCCCTGGTCCACC
ACCTCAGGAGGCCCCGCATA

Downstream 100 bases:

>100_bases
TGGAGCGCCGTAGCACAGACCTCCTCGTCCTGGGCGCCGGGGTGGCGGGGGTCTACGCCGCCTTGGCCGCGGAGGAGCGG
GGGGCCCGGGTCCTCCTCGT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MGRMRGEALAQEVLRLKRERNAVILAHSYQLPEVQEVADFVGDSLGLAREAQRTRAEVIVFCGVHFMAETAAILNPEKTV
LLPDLEAGCSLADSIRPEDVLAWKAKHPDGIVVAYVNTKAEVKALADVCVTSANAVEVVSRLPQDRPIYFVPDMFLGAHV
ARVTGRRLDLFPGECHVHAGIREEHLKALLEAHPGAEFLIHPECGCGSGCLYLKPDAKMLSTEGMVRYAKGAEAREFVVA
TEVGILHRLKKEAPEKAFFPVKPDAVCEYMKRITLEKVYLSLKEMRHVVRVPEEVAGRARRALEAMVAVG

Sequences:

>Translated_310_residues
MGRMRGEALAQEVLRLKRERNAVILAHSYQLPEVQEVADFVGDSLGLAREAQRTRAEVIVFCGVHFMAETAAILNPEKTV
LLPDLEAGCSLADSIRPEDVLAWKAKHPDGIVVAYVNTKAEVKALADVCVTSANAVEVVSRLPQDRPIYFVPDMFLGAHV
ARVTGRRLDLFPGECHVHAGIREEHLKALLEAHPGAEFLIHPECGCGSGCLYLKPDAKMLSTEGMVRYAKGAEAREFVVA
TEVGILHRLKKEAPEKAFFPVKPDAVCEYMKRITLEKVYLSLKEMRHVVRVPEEVAGRARRALEAMVAVG
>Mature_309_residues
GRMRGEALAQEVLRLKRERNAVILAHSYQLPEVQEVADFVGDSLGLAREAQRTRAEVIVFCGVHFMAETAAILNPEKTVL
LPDLEAGCSLADSIRPEDVLAWKAKHPDGIVVAYVNTKAEVKALADVCVTSANAVEVVSRLPQDRPIYFVPDMFLGAHVA
RVTGRRLDLFPGECHVHAGIREEHLKALLEAHPGAEFLIHPECGCGSGCLYLKPDAKMLSTEGMVRYAKGAEAREFVVAT
EVGILHRLKKEAPEKAFFPVKPDAVCEYMKRITLEKVYLSLKEMRHVVRVPEEVAGRARRALEAMVAVG

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=313, Percent_Identity=35.4632587859425, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34181; Mature: 34050

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRMRGEALAQEVLRLKRERNAVILAHSYQLPEVQEVADFVGDSLGLAREAQRTRAEVIV
CCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHEEE
FCGVHFMAETAAILNPEKTVLLPDLEAGCSLADSIRPEDVLAWKAKHPDGIVVAYVNTKA
EECHHHHHHHHHHCCCCCEEEECCCHHCCCHHHCCCCCCEEEEECCCCCCEEEEEECCHH
EVKALADVCVTSANAVEVVSRLPQDRPIYFVPDMFLGAHVARVTGRRLDLFPGECHVHAG
HHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCEEECCCCCEEEECC
IREEHLKALLEAHPGAEFLIHPECGCGSGCLYLKPDAKMLSTEGMVRYAKGAEAREFVVA
CHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCHHHHHCCCHHHHCCCCCCHHEEEH
TEVGILHRLKKEAPEKAFFPVKPDAVCEYMKRITLEKVYLSLKEMRHVVRVPEEVAGRAR
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RALEAMVAVG
HHHHHHHHCC
>Mature Secondary Structure 
GRMRGEALAQEVLRLKRERNAVILAHSYQLPEVQEVADFVGDSLGLAREAQRTRAEVIV
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHEEE
FCGVHFMAETAAILNPEKTVLLPDLEAGCSLADSIRPEDVLAWKAKHPDGIVVAYVNTKA
EECHHHHHHHHHHCCCCCEEEECCCHHCCCHHHCCCCCCEEEEECCCCCCEEEEEECCHH
EVKALADVCVTSANAVEVVSRLPQDRPIYFVPDMFLGAHVARVTGRRLDLFPGECHVHAG
HHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCEEECCCCCEEEECC
IREEHLKALLEAHPGAEFLIHPECGCGSGCLYLKPDAKMLSTEGMVRYAKGAEAREFVVA
CHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCHHHHHCCCHHHHCCCCCCHHEEEH
TEVGILHRLKKEAPEKAFFPVKPDAVCEYMKRITLEKVYLSLKEMRHVVRVPEEVAGRAR
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RALEAMVAVG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA