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The map label for this gene is nadB [H]

Identifier: 55980952

GI number: 55980952

Start: 925865

End: 927346

Strand: Reverse

Name: nadB [H]

Synonym: TTHA0983

Alternate gene names: 55980952

Gene position: 927346-925865 (Counterclockwise)

Preceding gene: 55980953

Following gene: 55980951

Centisome position: 50.13

GC content: 74.97

Gene sequence:

>1482_bases
ATGGAGCGCCGTAGCACAGACCTCCTCGTCCTGGGCGCCGGGGTGGCGGGGGTCTACGCCGCCTTGGCCGCGGAGGAGCG
GGGGGCCCGGGTCCTCCTCGTGAGCAAGGACCCCCTCCCCGCGGGCTCCACCCCCTGGGCCCAAGGGGGGGTGGCCTTTC
CCGTGGGGGAGGAGGACCTCGAGGCCCACCTCCGGGACACCCTCGTGGCCGGCCGGGGCCTCGTGGAGGAAGGGGTGGCC
CGCTCCATCCTGGAGGAGGCCCCCCGCCACCTGGAGAGGCTTCGCGCCTTCGGCCTTCCCTTCCACCCCGAGCCCACCCG
GGAAGGGGGGCACTCCCGCGCGAGGGTCTTCCACCTGGGCGGGGACCGGAGCGGGCTTCTCCTCCTCGAGGGGCTCCTTA
AGCGGCTTTCCACCCCCGTGGTCCCCGCCCAGGCCCTGAGCCTCCTCGTCTCCGGGAACCGGGTGGCCGGGGCCCTCCTC
TGGGGGCCGGGGGGGCTTTGGGAGGTCCGGGCTGGAGCCGTCCTCCTCGCCACGGGAGGGTTTGGCCGCCTCTTCCCTGT
GACCACGAACCCCCACGGGGCCACGGGGGACGGGATGGCCCTCGCCTGGCGGGCGGGGGCGGTGCTCCGGGACCTGGAGT
TCGTCCAGTTCCACCCCACGGCCCTTCCCAACGGGGCCCTGGTCTCCGAGGCCTGCCGGGGGGAGGGGGCCCTCCTCCTG
AACGCCCACGGGGAGCGGTTCATGCCCCGCTACGACCCCCTGGCGGAGCTCGCCCCACGGGACGTGGTGGCCCGGGCCGT
CTTCCGGGAGAGGGAGCGCACGGGCGGGGTTTACCTGGACCTGAGGCCAATCCCCCACCTGGAGGAGCGCTTCCCCACGG
TGGTGGCCCAGGCCCGGGCCTTGGGCCTGGACCCCCTGAGGGCGCCCCTTCCCGTGGCCCCGGCGGCCCACTACGCCATG
GGGGGGGTGAGGACCGACGCCTTCGGCCACACGGGGATCCCCGGGCTCTTCGCCGCGGGGGAGGTGGCCTCCACCGGCTT
CCACGGGGCGAACCGCCTGGCCTCCAACAGCCTCCTCGAGGGCCTGGTGGTGGGGTGGCGGGCCGCCCTAAGGGCCCTGG
AGGACCTGGCCTTTCCCCCAAGAGCCACCCCCCTCCCCGCCCTCGCCGCCCCACCCGAGGCGGTGGCGTCCCTAAGGGAG
GAAGCGGGGGAGGCCCTCGGGGTGGTGCGGCGGAAAGAAACCCTCCTCGCCTTCCTCCGCCGGGCGGAGGCCGTGCCCCT
GGAGGAGGTGGAACAGGCCAGCAGGGACCGGCTCGAGGCGGGAAGCCTCCTCCTCCTCATGCGCCTCCTCGCCCGGGCGG
CCTTGGCCCGGGAGGAGAGCCGGGGCGCCCACTTCCGGGAGGACTTCCCCCTGGAAGACCGCCCCAGGCACAGCCTCTTC
CAGGGGTGGCGCCTCGGTTTCCTTCCCGTGGGTGTGGAGTAG

Upstream 100 bases:

>100_bases
TCTACCTCTCCTTGAAGGAGATGCGCCACGTGGTCCGGGTGCCCGAGGAGGTGGCGGGGAGGGCGCGCCGGGCCCTCGAG
GCCATGGTGGCCGTGGGGTG

Downstream 100 bases:

>100_bases
GGGAGGAGGTCCTATGCAAGGCCACCCCGAGGTGATTCATAGCCTCAGGCAAGGCTTTCCGAGGAGCCCGCCGCCATCCT
CCAGTACATGGTGCACGCCG

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO; Quinolinate synthase B [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MERRSTDLLVLGAGVAGVYAALAAEERGARVLLVSKDPLPAGSTPWAQGGVAFPVGEEDLEAHLRDTLVAGRGLVEEGVA
RSILEEAPRHLERLRAFGLPFHPEPTREGGHSRARVFHLGGDRSGLLLLEGLLKRLSTPVVPAQALSLLVSGNRVAGALL
WGPGGLWEVRAGAVLLATGGFGRLFPVTTNPHGATGDGMALAWRAGAVLRDLEFVQFHPTALPNGALVSEACRGEGALLL
NAHGERFMPRYDPLAELAPRDVVARAVFRERERTGGVYLDLRPIPHLEERFPTVVAQARALGLDPLRAPLPVAPAAHYAM
GGVRTDAFGHTGIPGLFAAGEVASTGFHGANRLASNSLLEGLVVGWRAALRALEDLAFPPRATPLPALAAPPEAVASLRE
EAGEALGVVRRKETLLAFLRRAEAVPLEEVEQASRDRLEAGSLLLLMRLLARAALAREESRGAHFREDFPLEDRPRHSLF
QGWRLGFLPVGVE

Sequences:

>Translated_493_residues
MERRSTDLLVLGAGVAGVYAALAAEERGARVLLVSKDPLPAGSTPWAQGGVAFPVGEEDLEAHLRDTLVAGRGLVEEGVA
RSILEEAPRHLERLRAFGLPFHPEPTREGGHSRARVFHLGGDRSGLLLLEGLLKRLSTPVVPAQALSLLVSGNRVAGALL
WGPGGLWEVRAGAVLLATGGFGRLFPVTTNPHGATGDGMALAWRAGAVLRDLEFVQFHPTALPNGALVSEACRGEGALLL
NAHGERFMPRYDPLAELAPRDVVARAVFRERERTGGVYLDLRPIPHLEERFPTVVAQARALGLDPLRAPLPVAPAAHYAM
GGVRTDAFGHTGIPGLFAAGEVASTGFHGANRLASNSLLEGLVVGWRAALRALEDLAFPPRATPLPALAAPPEAVASLRE
EAGEALGVVRRKETLLAFLRRAEAVPLEEVEQASRDRLEAGSLLLLMRLLARAALAREESRGAHFREDFPLEDRPRHSLF
QGWRLGFLPVGVE
>Mature_493_residues
MERRSTDLLVLGAGVAGVYAALAAEERGARVLLVSKDPLPAGSTPWAQGGVAFPVGEEDLEAHLRDTLVAGRGLVEEGVA
RSILEEAPRHLERLRAFGLPFHPEPTREGGHSRARVFHLGGDRSGLLLLEGLLKRLSTPVVPAQALSLLVSGNRVAGALL
WGPGGLWEVRAGAVLLATGGFGRLFPVTTNPHGATGDGMALAWRAGAVLRDLEFVQFHPTALPNGALVSEACRGEGALLL
NAHGERFMPRYDPLAELAPRDVVARAVFRERERTGGVYLDLRPIPHLEERFPTVVAQARALGLDPLRAPLPVAPAAHYAM
GGVRTDAFGHTGIPGLFAAGEVASTGFHGANRLASNSLLEGLVVGWRAALRALEDLAFPPRATPLPALAAPPEAVASLRE
EAGEALGVVRRKETLLAFLRRAEAVPLEEVEQASRDRLEAGSLLLLMRLLARAALAREESRGAHFREDFPLEDRPRHSLF
QGWRLGFLPVGVE

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=555, Percent_Identity=33.3333333333333, Blast_Score=216, Evalue=5e-56,
Organism=Escherichia coli, GI1788928, Length=516, Percent_Identity=38.3720930232558, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI1790597, Length=513, Percent_Identity=35.0877192982456, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1786942, Length=561, Percent_Identity=34.4028520499109, Blast_Score=201, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17505833, Length=548, Percent_Identity=32.4817518248175, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17550100, Length=545, Percent_Identity=31.9266055045872, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71986328, Length=466, Percent_Identity=28.1115879828326, Blast_Score=92, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322701, Length=539, Percent_Identity=33.5807050092764, Blast_Score=216, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6322416, Length=551, Percent_Identity=33.3938294010889, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI17137288, Length=544, Percent_Identity=33.8235294117647, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24655642, Length=544, Percent_Identity=33.8235294117647, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24655647, Length=544, Percent_Identity=33.8235294117647, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24663005, Length=519, Percent_Identity=31.9845857418112, Blast_Score=184, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 52663; Mature: 52663

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRSTDLLVLGAGVAGVYAALAAEERGARVLLVSKDPLPAGSTPWAQGGVAFPVGEEDL
CCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCHHHH
EAHLRDTLVAGRGLVEEGVARSILEEAPRHLERLRAFGLPFHPEPTREGGHSRARVFHLG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
GDRSGLLLLEGLLKRLSTPVVPAQALSLLVSGNRVAGALLWGPGGLWEVRAGAVLLATGG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEECCCEEEEEECC
FGRLFPVTTNPHGATGDGMALAWRAGAVLRDLEFVQFHPTALPNGALVSEACRGEGALLL
CCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCEEEE
NAHGERFMPRYDPLAELAPRDVVARAVFRERERTGGVYLDLRPIPHLEERFPTVVAQARA
ECCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
LGLDPLRAPLPVAPAAHYAMGGVRTDAFGHTGIPGLFAAGEVASTGFHGANRLASNSLLE
CCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHH
GLVVGWRAALRALEDLAFPPRATPLPALAAPPEAVASLREEAGEALGVVRRKETLLAFLR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEAVPLEEVEQASRDRLEAGSLLLLMRLLARAALAREESRGAHFREDFPLEDRPRHSLF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
QGWRLGFLPVGVE
HCCCCCCEECCCC
>Mature Secondary Structure
MERRSTDLLVLGAGVAGVYAALAAEERGARVLLVSKDPLPAGSTPWAQGGVAFPVGEEDL
CCCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCHHHH
EAHLRDTLVAGRGLVEEGVARSILEEAPRHLERLRAFGLPFHPEPTREGGHSRARVFHLG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
GDRSGLLLLEGLLKRLSTPVVPAQALSLLVSGNRVAGALLWGPGGLWEVRAGAVLLATGG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEECCCEEEEEECC
FGRLFPVTTNPHGATGDGMALAWRAGAVLRDLEFVQFHPTALPNGALVSEACRGEGALLL
CCEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCEEEE
NAHGERFMPRYDPLAELAPRDVVARAVFRERERTGGVYLDLRPIPHLEERFPTVVAQARA
ECCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
LGLDPLRAPLPVAPAAHYAMGGVRTDAFGHTGIPGLFAAGEVASTGFHGANRLASNSLLE
CCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHH
GLVVGWRAALRALEDLAFPPRATPLPALAAPPEAVASLREEAGEALGVVRRKETLLAFLR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEAVPLEEVEQASRDRLEAGSLLLLMRLLARAALAREESRGAHFREDFPLEDRPRHSLF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
QGWRLGFLPVGVE
HCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]