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The map label for this gene is lacF [H]

Identifier: 55980946

GI number: 55980946

Start: 920334

End: 921179

Strand: Reverse

Name: lacF [H]

Synonym: TTHA0977

Alternate gene names: 55980946

Gene position: 921179-920334 (Counterclockwise)

Preceding gene: 55980947

Following gene: 55980945

Centisome position: 49.8

GC content: 68.56

Gene sequence:

>846_bases
ATGAAGGACCGGTACCTTCCTTACCTTCTGATCCTTCCCTCCGTCCTCTTCCTCCTGGTCTTCTTCGGCTGGCCCCTCCT
CAGCGCCCTGGTCCTCGCCTTCCGGGAAGGGGAGGGGGTGGGCTTGGGCAACTTCCGCAGGATGGCCCAGGACCTCTACT
TTGGGGACGCCCTGCGGAACACCCTCTTCCTCACCGCCATCGTGGTCCCGCTCCAGCTCGCTTTAGCCCTGGCCATGGGC
CTCCTCCTGGAACGCCTCGGGCGCGGGCGCGACCTCTTCCTCTACTTCTGGACCGTGCCCCTCGGGATCTCGGACCTGGC
GGCGGGGATCGTGTGGCTTTCCATCTTCACCGAGCGGGGCTACCTCAACACCCTCCTCCACGCCCTCGGGGTCCTGGAGG
AGCCCGTGGGCTGGCTCACCTACGAGCACCCCACGGCCCTCTTCCTCGCCGTGGTGGCGGCGGAGGTCTGGCGGGCCACG
CCCTTGGTCCTCGTCATCCTGGTGGCGGGCCTCCAGCTCATCCCCAGGGAGCTGCACGAGGCGGCCGAGGTCTTCGGGGC
CACGCCCTGGGTCCGGTTCCGGAAGGTGACCCTCCCCCTCCTCAAGCCCAGCATCCAGACGGCCTTGATCCTGCGCACGG
TCCTCGCCTTTGAGGTCTTCGCCGTGGTGGTGGCCCTCTCCGGCCGGAACCTGCCGGTGCTGGCGGGGGAGGCCTACTTC
TGGTACGCCGACTACCAGAACCCGGGGGTGGCGGCGGCCTACGCCGTCCTCATCCTCCTCGTCTCCGTGGCCGCCACCCT
CTTTTACCTCCGGGCCCTCCGCGTCCGGGAGGAGGTGTACGGATGA

Upstream 100 bases:

>100_bases
AGCGGGAGGGCTTCCGGGAGTACTACGACCCCCTTACGGGGCAGGGGAGGGGGGGTGAGGGCTTCTCCTGGAGCGCCGCC
TTGGCCCTCTTCTGGACGCG

Downstream 100 bases:

>100_bases
GCCGGGTATGGCCCTGGCTTCTCGCCCTCGTCTTCACCTTCTGGGTGCTCCTTCCCATCTACCTCATCGCCCTGAGCGCC
TTCGCTCCCAGGGAGGCGGT

Product: sugar ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKDRYLPYLLILPSVLFLLVFFGWPLLSALVLAFREGEGVGLGNFRRMAQDLYFGDALRNTLFLTAIVVPLQLALALAMG
LLLERLGRGRDLFLYFWTVPLGISDLAAGIVWLSIFTERGYLNTLLHALGVLEEPVGWLTYEHPTALFLAVVAAEVWRAT
PLVLVILVAGLQLIPRELHEAAEVFGATPWVRFRKVTLPLLKPSIQTALILRTVLAFEVFAVVVALSGRNLPVLAGEAYF
WYADYQNPGVAAAYAVLILLVSVAATLFYLRALRVREEVYG

Sequences:

>Translated_281_residues
MKDRYLPYLLILPSVLFLLVFFGWPLLSALVLAFREGEGVGLGNFRRMAQDLYFGDALRNTLFLTAIVVPLQLALALAMG
LLLERLGRGRDLFLYFWTVPLGISDLAAGIVWLSIFTERGYLNTLLHALGVLEEPVGWLTYEHPTALFLAVVAAEVWRAT
PLVLVILVAGLQLIPRELHEAAEVFGATPWVRFRKVTLPLLKPSIQTALILRTVLAFEVFAVVVALSGRNLPVLAGEAYF
WYADYQNPGVAAAYAVLILLVSVAATLFYLRALRVREEVYG
>Mature_281_residues
MKDRYLPYLLILPSVLFLLVFFGWPLLSALVLAFREGEGVGLGNFRRMAQDLYFGDALRNTLFLTAIVVPLQLALALAMG
LLLERLGRGRDLFLYFWTVPLGISDLAAGIVWLSIFTERGYLNTLLHALGVLEEPVGWLTYEHPTALFLAVVAAEVWRAT
PLVLVILVAGLQLIPRELHEAAEVFGATPWVRFRKVTLPLLKPSIQTALILRTVLAFEVFAVVVALSGRNLPVLAGEAYF
WYADYQNPGVAAAYAVLILLVSVAATLFYLRALRVREEVYG

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=259, Percent_Identity=30.1158301158301, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789861, Length=237, Percent_Identity=29.535864978903, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31231; Mature: 31231

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRYLPYLLILPSVLFLLVFFGWPLLSALVLAFREGEGVGLGNFRRMAQDLYFGDALRN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TLFLTAIVVPLQLALALAMGLLLERLGRGRDLFLYFWTVPLGISDLAAGIVWLSIFTERG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHCCC
YLNTLLHALGVLEEPVGWLTYEHPTALFLAVVAAEVWRATPLVLVILVAGLQLIPRELHE
HHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEVFGATPWVRFRKVTLPLLKPSIQTALILRTVLAFEVFAVVVALSGRNLPVLAGEAYF
HHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEE
WYADYQNPGVAAAYAVLILLVSVAATLFYLRALRVREEVYG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDRYLPYLLILPSVLFLLVFFGWPLLSALVLAFREGEGVGLGNFRRMAQDLYFGDALRN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TLFLTAIVVPLQLALALAMGLLLERLGRGRDLFLYFWTVPLGISDLAAGIVWLSIFTERG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHCCC
YLNTLLHALGVLEEPVGWLTYEHPTALFLAVVAAEVWRATPLVLVILVAGLQLIPRELHE
HHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAEVFGATPWVRFRKVTLPLLKPSIQTALILRTVLAFEVFAVVVALSGRNLPVLAGEAYF
HHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEE
WYADYQNPGVAAAYAVLILLVSVAATLFYLRALRVREEVYG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]