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The map label for this gene is maoC [H]

Identifier: 55980937

GI number: 55980937

Start: 912076

End: 914082

Strand: Reverse

Name: maoC [H]

Synonym: TTHA0968

Alternate gene names: 55980937

Gene position: 914082-912076 (Counterclockwise)

Preceding gene: 55980938

Following gene: 55980925

Centisome position: 49.42

GC content: 71.8

Gene sequence:

>2007_bases
ATGAAGCTCCAAAGCTACCTCATGGGCGAGTGGCGGGAAGGCCAGGGCGAGGGCGTCCCCGTGCGGGACGCGAGCACGGG
GGAGGTCCTCGCCCGGGTGACGGCGGAGGGCCTCCCCGTGAAGGAGGCCGTGGCCTGGGGCCGGGAGGTGGGCGGAAAGG
CCCTTTTGGCCCTGGGCTTCCAGGAACGGGGAAGGCGGCTTAGGGCCCTGGCCCAGTACCTCTCCGAGCGGAAGGAGGCC
CTCTACCGCCTCTACGCCACCACGGGGGGGACGAGGCGGGACGCCTGGTACGACGTGGACGGGGGGATCGGGGTCCTTTA
CGCCTATAGCTCCCTCGCCCGCAACCTCCCCGAGGGCAACCTCCTCCCCGAGGACGACTTCCTTCCCCTCTCCAAGGACC
TCTCTTTCCAGGGGAGGCACGTCCTCGCCCCCAAGGGGGGGATCACCGTCCAGATCAACGCCTTCAACTTCCCCGTATGG
GGGCTCTTGGAGAAGTTCGCCCCCGCCTTCCTCGCGGGGGTCCCCACCCTGGCGAAGCCCGCCACCCCCACGGCCCACGT
GGCCGAGGCCCTGGTGCGGACGATGCTGGAGTCGGGCCTCCTCCCGGAAGGGAGCCTCCAGCTCCTCGTGGGAAGCGTGG
GGGACCTCTTTGACGCCCTGGACCACCGGGACAGCGTCTTCTTCACCGGGTCCAAGGCCACCGCCGACCGCCTCCGCCGC
CACCCGGCCTTCCTGGAGCGGGGGGCCCTCTTCAACGCCGAGGCCGACTCCCTAAACCCCGCCATCCTGGGGGAAAAGGC
CACGGAGGAGGAGCTTTCCCGCCTCGCCCAGGAGATCGCCCAGGAGCTCGTCATCAAGACGGGGCAGCGCTGCACCGCCA
TCCGCCGGGTCTTTGCGCCAAGGGAGCGCCTTAAGGCCCTCCTCGAGGCCACCCGAAAGCGCCTCGAGGCCTTAAGGCTC
GGCGACCCCCGGGAGGAGGGCGTGGACCTCGGGCCTTTGGCCTCCTTGGAGCAGAAGGCGGAGGTGGAAAAAGCGGTGGC
GGCCCTCCTGGAGGCGGGGGCCCGGGTCTACTGGAGGCACCCCGGGCGGGAGGACGGGGCCTTCTTCCCCCCCACCCTCC
TCCTCGCCGAGGACCCCTGGCCCGGGGCCCTCCACCAGGTGGAGCCCTTCGGCCCCGTGGCCACCTTCTTCCCCTACGGA
AGCCGGGAGGAGGCGGCGAGGCTTGCCGCTTTGGGCGGGGGAAGCCTCGTGGCCACCCTCGCCACCTCCGACCCCGAGGA
GGCGCGCTTTTACCTCCTGGCCCTCGCCCCCTACGTGGGGCGGCTTCACCTCCTGAACGCCCGCACCGCGGCCTCCTCCA
CGGGGCACGGCTCCCCCCTCCCCCGCCTCCTCCACGGCGGGCCAGGGCGGGCGGGAGGGGGCGAGGAGCTCGGCGGCCTC
CTCTCCGTGAGGCGCCACCTCGGGCGGGTCGCCCTCCAGGCCGACCCCTGGCTCCTCTCCGCCCTCACCGGGGAGTACGC
CAAGGGGGCGGAAAAGCCCGCGGAGGTCCACCCCTTCCGCAAGGCCTACGAGGACCTCGAGGTGGGCGAGACCCTCACCA
CCCACCGCCGCACCGTCACCGAAGCGGACATCGCCCTCTTCTCCGCCCTCTCCTGGGACCACTTCTACGCCCACACGGAC
GAGATCGCCGCCAGGGAGAGCCTCTTCGGGAAGCGGGTGGCCCACGGCTACTTCGTCCTCTCCGCCGCAGCGGGGCTTTT
CGTGGACCCCGCCCCGGGCCCGGTGCTCGCCAACTACGGCCTCGAGGGCCTGCGCTTCCTGGAGCCCGTGGGGGCCGGGG
ACACCCTCCAGGTCCGCCTCACGGTGAAGCGCAAGCGCCCCCGGGACGAAAAGACGGGCGTGGTGGAGTGGGCCGCGGAG
GTGGTGAACCAGGAAGGGAAGCCGGTCGCCACCTACACCGTCCTCACCCTGGTGGCCCGAAAGGGGGCCTTGGCGAAGGG
TTCCTGA

Upstream 100 bases:

>100_bases
AGAACCCCTTCGGGGCCACGCTTTGCAAGACGCTCTACCAGTGCGCCGCTTGCGGCGAGGTCTTTGAGGCCTTTAAGACC
GTCTAGGGAAAGGACGCGCG

Downstream 100 bases:

>100_bases
GCCGGGACAGAGGGACGCACGCCGAGGAGGCGGGGGGTCCCCCTACGAGGGCGACCGCTCCGCCTCCCACCGCTCCTTGA
GCCTCCGGAAGAGGGCCTCC

Product: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: Phenylacetic acid degradation protein paaZ [H]

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MKLQSYLMGEWREGQGEGVPVRDASTGEVLARVTAEGLPVKEAVAWGREVGGKALLALGFQERGRRLRALAQYLSERKEA
LYRLYATTGGTRRDAWYDVDGGIGVLYAYSSLARNLPEGNLLPEDDFLPLSKDLSFQGRHVLAPKGGITVQINAFNFPVW
GLLEKFAPAFLAGVPTLAKPATPTAHVAEALVRTMLESGLLPEGSLQLLVGSVGDLFDALDHRDSVFFTGSKATADRLRR
HPAFLERGALFNAEADSLNPAILGEKATEEELSRLAQEIAQELVIKTGQRCTAIRRVFAPRERLKALLEATRKRLEALRL
GDPREEGVDLGPLASLEQKAEVEKAVAALLEAGARVYWRHPGREDGAFFPPTLLLAEDPWPGALHQVEPFGPVATFFPYG
SREEAARLAALGGGSLVATLATSDPEEARFYLLALAPYVGRLHLLNARTAASSTGHGSPLPRLLHGGPGRAGGGEELGGL
LSVRRHLGRVALQADPWLLSALTGEYAKGAEKPAEVHPFRKAYEDLEVGETLTTHRRTVTEADIALFSALSWDHFYAHTD
EIAARESLFGKRVAHGYFVLSAAAGLFVDPAPGPVLANYGLEGLRFLEPVGAGDTLQVRLTVKRKRPRDEKTGVVEWAAE
VVNQEGKPVATYTVLTLVARKGALAKGS

Sequences:

>Translated_668_residues
MKLQSYLMGEWREGQGEGVPVRDASTGEVLARVTAEGLPVKEAVAWGREVGGKALLALGFQERGRRLRALAQYLSERKEA
LYRLYATTGGTRRDAWYDVDGGIGVLYAYSSLARNLPEGNLLPEDDFLPLSKDLSFQGRHVLAPKGGITVQINAFNFPVW
GLLEKFAPAFLAGVPTLAKPATPTAHVAEALVRTMLESGLLPEGSLQLLVGSVGDLFDALDHRDSVFFTGSKATADRLRR
HPAFLERGALFNAEADSLNPAILGEKATEEELSRLAQEIAQELVIKTGQRCTAIRRVFAPRERLKALLEATRKRLEALRL
GDPREEGVDLGPLASLEQKAEVEKAVAALLEAGARVYWRHPGREDGAFFPPTLLLAEDPWPGALHQVEPFGPVATFFPYG
SREEAARLAALGGGSLVATLATSDPEEARFYLLALAPYVGRLHLLNARTAASSTGHGSPLPRLLHGGPGRAGGGEELGGL
LSVRRHLGRVALQADPWLLSALTGEYAKGAEKPAEVHPFRKAYEDLEVGETLTTHRRTVTEADIALFSALSWDHFYAHTD
EIAARESLFGKRVAHGYFVLSAAAGLFVDPAPGPVLANYGLEGLRFLEPVGAGDTLQVRLTVKRKRPRDEKTGVVEWAAE
VVNQEGKPVATYTVLTLVARKGALAKGS
>Mature_668_residues
MKLQSYLMGEWREGQGEGVPVRDASTGEVLARVTAEGLPVKEAVAWGREVGGKALLALGFQERGRRLRALAQYLSERKEA
LYRLYATTGGTRRDAWYDVDGGIGVLYAYSSLARNLPEGNLLPEDDFLPLSKDLSFQGRHVLAPKGGITVQINAFNFPVW
GLLEKFAPAFLAGVPTLAKPATPTAHVAEALVRTMLESGLLPEGSLQLLVGSVGDLFDALDHRDSVFFTGSKATADRLRR
HPAFLERGALFNAEADSLNPAILGEKATEEELSRLAQEIAQELVIKTGQRCTAIRRVFAPRERLKALLEATRKRLEALRL
GDPREEGVDLGPLASLEQKAEVEKAVAALLEAGARVYWRHPGREDGAFFPPTLLLAEDPWPGALHQVEPFGPVATFFPYG
SREEAARLAALGGGSLVATLATSDPEEARFYLLALAPYVGRLHLLNARTAASSTGHGSPLPRLLHGGPGRAGGGEELGGL
LSVRRHLGRVALQADPWLLSALTGEYAKGAEKPAEVHPFRKAYEDLEVGETLTTHRRTVTEADIALFSALSWDHFYAHTD
EIAARESLFGKRVAHGYFVLSAAAGLFVDPAPGPVLANYGLEGLRFLEPVGAGDTLQVRLTVKRKRPRDEKTGVVEWAAE
VVNQEGKPVATYTVLTLVARKGALAKGS

Specific function: Phenylacetic acid aerobic catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=477, Percent_Identity=25.5765199161426, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI153266822, Length=486, Percent_Identity=25.5144032921811, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI25777730, Length=499, Percent_Identity=25.6513026052104, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI25777724, Length=485, Percent_Identity=23.9175257731959, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI21361176, Length=436, Percent_Identity=24.3119266055046, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI115387104, Length=494, Percent_Identity=24.8987854251012, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI25777728, Length=425, Percent_Identity=24, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI4507229, Length=456, Percent_Identity=26.7543859649123, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI238814322, Length=502, Percent_Identity=21.9123505976096, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1787653, Length=675, Percent_Identity=50.962962962963, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=420, Percent_Identity=27.8571428571429, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786504, Length=507, Percent_Identity=26.232741617357, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1787715, Length=514, Percent_Identity=26.2645914396887, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787684, Length=283, Percent_Identity=28.2685512367491, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787250, Length=357, Percent_Identity=28.0112044817927, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788042, Length=469, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081926, Length=338, Percent_Identity=28.4023668639053, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081896, Length=371, Percent_Identity=25.0673854447439, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87082295, Length=282, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25143876, Length=453, Percent_Identity=25.3863134657837, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25143874, Length=453, Percent_Identity=25.3863134657837, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551164, Length=291, Percent_Identity=24.3986254295533, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI133930964, Length=348, Percent_Identity=26.7241379310345, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115532534, Length=347, Percent_Identity=27.3775216138329, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17534447, Length=347, Percent_Identity=27.3775216138329, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562198, Length=437, Percent_Identity=23.3409610983982, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32564151, Length=270, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71986308, Length=414, Percent_Identity=24.3961352657005, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=338, Percent_Identity=26.0355029585799, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324950, Length=434, Percent_Identity=25.1152073732719, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323822, Length=449, Percent_Identity=22.9398663697105, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323821, Length=449, Percent_Identity=22.271714922049, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362580, Length=274, Percent_Identity=25.9124087591241, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI62472918, Length=274, Percent_Identity=25.9124087591241, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI62472926, Length=274, Percent_Identity=25.9124087591241, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI62472936, Length=274, Percent_Identity=25.9124087591241, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356737, Length=274, Percent_Identity=25.9124087591241, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20129399, Length=507, Percent_Identity=24.0631163708087, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR002539
- InterPro:   IPR011966 [H]

Pfam domain/function: PF00171 Aldedh; PF01575 MaoC_dehydratas [H]

EC number: NA

Molecular weight: Translated: 72201; Mature: 72201

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQSYLMGEWREGQGEGVPVRDASTGEVLARVTAEGLPVKEAVAWGREVGGKALLALGF
CCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECH
QERGRRLRALAQYLSERKEALYRLYATTGGTRRDAWYDVDGGIGVLYAYSSLARNLPEGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCC
LLPEDDFLPLSKDLSFQGRHVLAPKGGITVQINAFNFPVWGLLEKFAPAFLAGVPTLAKP
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCC
ATPTAHVAEALVRTMLESGLLPEGSLQLLVGSVGDLFDALDHRDSVFFTGSKATADRLRR
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
HPAFLERGALFNAEADSLNPAILGEKATEEELSRLAQEIAQELVIKTGQRCTAIRRVFAP
CHHHHHCCCEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
RERLKALLEATRKRLEALRLGDPREEGVDLGPLASLEQKAEVEKAVAALLEAGARVYWRH
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
PGREDGAFFPPTLLLAEDPWPGALHQVEPFGPVATFFPYGSREEAARLAALGGGSLVATL
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCEEEEE
ATSDPEEARFYLLALAPYVGRLHLLNARTAASSTGHGSPLPRLLHGGPGRAGGGEELGGL
ECCCCHHHHEEEEEHHHHHCCEEEEECHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHH
LSVRRHLGRVALQADPWLLSALTGEYAKGAEKPAEVHPFRKAYEDLEVGETLTTHRRTVT
HHHHHHHHHEEECCCCHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
EADIALFSALSWDHFYAHTDEIAARESLFGKRVAHGYFVLSAAAGLFVDPAPGPVLANYG
HHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCCCEEECCC
LEGLRFLEPVGAGDTLQVRLTVKRKRPRDEKTGVVEWAAEVVNQEGKPVATYTVLTLVAR
CCHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KGALAKGS
CCCCCCCC
>Mature Secondary Structure
MKLQSYLMGEWREGQGEGVPVRDASTGEVLARVTAEGLPVKEAVAWGREVGGKALLALGF
CCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECH
QERGRRLRALAQYLSERKEALYRLYATTGGTRRDAWYDVDGGIGVLYAYSSLARNLPEGN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCC
LLPEDDFLPLSKDLSFQGRHVLAPKGGITVQINAFNFPVWGLLEKFAPAFLAGVPTLAKP
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCC
ATPTAHVAEALVRTMLESGLLPEGSLQLLVGSVGDLFDALDHRDSVFFTGSKATADRLRR
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHH
HPAFLERGALFNAEADSLNPAILGEKATEEELSRLAQEIAQELVIKTGQRCTAIRRVFAP
CHHHHHCCCEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
RERLKALLEATRKRLEALRLGDPREEGVDLGPLASLEQKAEVEKAVAALLEAGARVYWRH
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
PGREDGAFFPPTLLLAEDPWPGALHQVEPFGPVATFFPYGSREEAARLAALGGGSLVATL
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCEEEEE
ATSDPEEARFYLLALAPYVGRLHLLNARTAASSTGHGSPLPRLLHGGPGRAGGGEELGGL
ECCCCHHHHEEEEEHHHHHCCEEEEECHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHH
LSVRRHLGRVALQADPWLLSALTGEYAKGAEKPAEVHPFRKAYEDLEVGETLTTHRRTVT
HHHHHHHHHEEECCCCHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
EADIALFSALSWDHFYAHTDEIAARESLFGKRVAHGYFVLSAAAGLFVDPAPGPVLANYG
HHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCCCEEECCC
LEGLRFLEPVGAGDTLQVRLTVKRKRPRDEKTGVVEWAAEVVNQEGKPVATYTVLTLVAR
CCHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KGALAKGS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]