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The map label for this gene is tig [H]

Identifier: 55980583

GI number: 55980583

Start: 583009

End: 584223

Strand: Direct

Name: tig [H]

Synonym: TTHA0614

Alternate gene names: 55980583

Gene position: 583009-584223 (Clockwise)

Preceding gene: 55980582

Following gene: 55980584

Centisome position: 31.52

GC content: 69.63

Gene sequence:

>1215_bases
GTGGCGGAGATCCTGGAGCGTTCCGGCTATCTGGTCAAGGTGCGGGTGGAGGTGCCCGCCGACCGGGTGAAGGCGAGCTA
CGAGGCCCTGCTTAAGGACCTCGCCTCCCGGGTGCGGGTGCCCGGCTTCCGGCCGGGCAAGGCCCCCCTGAAGGTGGTGG
AGGCCCGCCTGGGCCGGGAGGCGCTCCTCCAAGACCTTAAGGAGCGCCTGGTGGAGGAGACCTACCCCGAGGCGGTGCGG
GAGCTCGGCCTAAGCCCCGTGGCCGCCCGCGTGGTGGAGCAGGACCTGAGCGAGGGGGAGGGCTTCCGCTACGTGGCCGA
GGTGGAGAACTACCCCGAGGTGAGGCTTCCCGACTGGCGGAGCTTCGCCTTGGAGGTCTCCCCGCCCGAGGTCACCGAGG
AGATGGTGGAGAAGGCCCTGGAGGAGCTCCGCCAGCGCTACGCCGAGCTCGTCCCCGTGGAGCGGGAGGCCCAGGAAAAG
GACCACCTCTTCGTCCGCACCGAGGAGGGGGCGGAGTTCCCCATTGACCTCGCTAAAGCCCTTCCCCACGTGCGGGAGGC
CCTCCTCGGCAAGAAGGCGGGGGACGTGGTCATGGTCCCCGTGCTGAACGACAAGGGCGAGAAGGTGCGGGAGGTCAGGA
CCGAGGTCCTCGAGGTCAAGACCCTGAAGCTCCCCGAGCTGGACGAGGAGTTCGCCAAGACCCTGGAGGCGGAAAGCCTC
GAGGACCTCAAAAACCGGGTGCGGGAAAGCCTCAAGCGCCAGGCGGAGCGGGCCTACGAGGAGGCCAGGGAGCGGGCCTT
CTTGGAGAAGCTCGCCGAGGGCCTGGAGGTGGAGATCCCCCCTTCCATGCTCCGGGCGGAGGAGCGCCACCTCCTGGAGC
ACCTGGCCGAGGACCTCTACCGGCAGGGGATCAGCCTGGAGGCCTACCTCGAGGCCCTGAAGGAGAAGGGGGAGTTGGAG
AAGTTCCAGGAGGACCTGCGCAAGGAGGCGGAGAAGCGGGTCCGCATCGCCCTCGCCCGGGAGAAGCTCGCCGAGGAGCT
CAACCCCGAGGTCTCCGAGGAGGAGTGGCAGGCCTACCTCCAGGCCGCGGCCCGGGCCTACGGCGTTGCCGTCCAGGACC
TTCGCCGCCAGTTCGGCGAGGAGGGCCTCGCCCGGCTTAAGGAGCGCCTCCGCCAGGACAAGGCGGTGCAGGAGGCCCTG
AAGGCCCTGGGCTGA

Upstream 100 bases:

>100_bases
ACGCGCCGGACTTAGGATCCGGTGGGGCAACCCGTGCGGGTTCAAGTCCCGCTCCTCGCACCATCCGGGCGGCCCCCCTT
TCATCGGGACGAGGTGAAAC

Downstream 100 bases:

>100_bases
GGGCCTGGAACATGGTGGCCCAGGGGGGTTTCCCCCCTGGGTCTGCCGCTAAACTAAGGATTGGTATGGTCATACCCTAC
GTCATTGAGCAGACGGCCCG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAEILERSGYLVKVRVEVPADRVKASYEALLKDLASRVRVPGFRPGKAPLKVVEARLGREALLQDLKERLVEETYPEAVR
ELGLSPVAARVVEQDLSEGEGFRYVAEVENYPEVRLPDWRSFALEVSPPEVTEEMVEKALEELRQRYAELVPVEREAQEK
DHLFVRTEEGAEFPIDLAKALPHVREALLGKKAGDVVMVPVLNDKGEKVREVRTEVLEVKTLKLPELDEEFAKTLEAESL
EDLKNRVRESLKRQAERAYEEARERAFLEKLAEGLEVEIPPSMLRAEERHLLEHLAEDLYRQGISLEAYLEALKEKGELE
KFQEDLRKEAEKRVRIALAREKLAEELNPEVSEEEWQAYLQAAARAYGVAVQDLRRQFGEEGLARLKERLRQDKAVQEAL
KALG

Sequences:

>Translated_404_residues
MAEILERSGYLVKVRVEVPADRVKASYEALLKDLASRVRVPGFRPGKAPLKVVEARLGREALLQDLKERLVEETYPEAVR
ELGLSPVAARVVEQDLSEGEGFRYVAEVENYPEVRLPDWRSFALEVSPPEVTEEMVEKALEELRQRYAELVPVEREAQEK
DHLFVRTEEGAEFPIDLAKALPHVREALLGKKAGDVVMVPVLNDKGEKVREVRTEVLEVKTLKLPELDEEFAKTLEAESL
EDLKNRVRESLKRQAERAYEEARERAFLEKLAEGLEVEIPPSMLRAEERHLLEHLAEDLYRQGISLEAYLEALKEKGELE
KFQEDLRKEAEKRVRIALAREKLAEELNPEVSEEEWQAYLQAAARAYGVAVQDLRRQFGEEGLARLKERLRQDKAVQEAL
KALG
>Mature_403_residues
AEILERSGYLVKVRVEVPADRVKASYEALLKDLASRVRVPGFRPGKAPLKVVEARLGREALLQDLKERLVEETYPEAVRE
LGLSPVAARVVEQDLSEGEGFRYVAEVENYPEVRLPDWRSFALEVSPPEVTEEMVEKALEELRQRYAELVPVEREAQEKD
HLFVRTEEGAEFPIDLAKALPHVREALLGKKAGDVVMVPVLNDKGEKVREVRTEVLEVKTLKLPELDEEFAKTLEAESLE
DLKNRVRESLKRQAERAYEEARERAFLEKLAEGLEVEIPPSMLRAEERHLLEHLAEDLYRQGISLEAYLEALKEKGELEK
FQEDLRKEAEKRVRIALAREKLAEELNPEVSEEEWQAYLQAAARAYGVAVQDLRRQFGEEGLARLKERLRQDKAVQEALK
ALG

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=299, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 46288; Mature: 46157

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEILERSGYLVKVRVEVPADRVKASYEALLKDLASRVRVPGFRPGKAPLKVVEARLGRE
CCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHH
ALLQDLKERLVEETYPEAVRELGLSPVAARVVEQDLSEGEGFRYVAEVENYPEVRLPDWR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCHH
SFALEVSPPEVTEEMVEKALEELRQRYAELVPVEREAQEKDHLFVRTEEGAEFPIDLAKA
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCCCHHHHHH
LPHVREALLGKKAGDVVMVPVLNDKGEKVREVRTEVLEVKTLKLPELDEEFAKTLEAESL
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EDLKNRVRESLKRQAERAYEEARERAFLEKLAEGLEVEIPPSMLRAEERHLLEHLAEDLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHH
RQGISLEAYLEALKEKGELEKFQEDLRKEAEKRVRIALAREKLAEELNPEVSEEEWQAYL
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
QAAARAYGVAVQDLRRQFGEEGLARLKERLRQDKAVQEALKALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEILERSGYLVKVRVEVPADRVKASYEALLKDLASRVRVPGFRPGKAPLKVVEARLGRE
CHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCHH
ALLQDLKERLVEETYPEAVRELGLSPVAARVVEQDLSEGEGFRYVAEVENYPEVRLPDWR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCCCCHH
SFALEVSPPEVTEEMVEKALEELRQRYAELVPVEREAQEKDHLFVRTEEGAEFPIDLAKA
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCCCHHHHHH
LPHVREALLGKKAGDVVMVPVLNDKGEKVREVRTEVLEVKTLKLPELDEEFAKTLEAESL
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EDLKNRVRESLKRQAERAYEEARERAFLEKLAEGLEVEIPPSMLRAEERHLLEHLAEDLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHH
RQGISLEAYLEALKEKGELEKFQEDLRKEAEKRVRIALAREKLAEELNPEVSEEEWQAYL
HCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
QAAARAYGVAVQDLRRQFGEEGLARLKERLRQDKAVQEALKALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA