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The map label for this gene is paaF [C]

Identifier: 54296892

GI number: 54296892

Start: 1036854

End: 1037912

Strand: Direct

Name: paaF [C]

Synonym: lpp0933

Alternate gene names: 54296892

Gene position: 1036854-1037912 (Clockwise)

Preceding gene: 54296891

Following gene: 54296894

Centisome position: 29.59

GC content: 40.13

Gene sequence:

>1059_bases
ATGACTGAAGAGGTGCTGTTTTCTCAGGAAGGTCAATTGGGATTCATTACTTTAAATCGACCAAAGGCTTTAAATGCTTT
AACTTTAACCATGATCATGGCACTGCAAAAGCAATTGTCAATTTGGAAAGAAGATAATTCTATTAAAGCAGTCGTCGTAC
AAGCTGTTCCGGGTAATGCTTTTTGCGCAGGTGGTGATATTCGTTGGCTATATAATGCGGGCCGTAGTAAAGACTCTGAG
CAGATGCAGTTCTTTTGGCATGAGTACAGGTTAAACCATTTTATTCATCATTTTGGTAAACCTTATATTTCTTTGCTGGA
TGGGATTACTATGGGAGGAGGGGTCGGTATTTCCTTACATGGAAGCCACCCTGTTGCCAGTGAGCGTTTTGTATTTGCAA
TGCCAGAAACAGGGATTGGTTTTTTTCCTGATATTGGTGCCAGCTATTTATTAAACAAATGCCCAGGGTTTTTAGGAGTC
TATTTGGGGTTAACCGGAAATAAATTGGGTCCTCATGATGCCAGGAAGGCAGGGTTAGTGAAGCAGATTGTCTTTGCAGA
GCAAATGCAGTCAATGATTGAGGCATTAAAGAGAGAAGATTTATCAGAAGATGCTTTCAATCTTGTTGATCAATGCATTT
CTTCTTTTGCAAGTGATGCCATGCCCACCGAGGCAAGTCAAATCAAACCTTTAATCGATGTCTGTTTCTCCAAGCCTAGT
GTTGAACTAATAAGAGAGTCTTTACAGAGCACAGACGGTGTGTGGGCTCTTGGGGTGGATAATACTTTGCTGCAAAAATC
GCCTCTGAGCCTTAAGATAACCCTTGCACAAATCCAAAAAGCCAAGGGCTTATCTTTAGCAGAATGTTTAAAAATGGATT
TCGATCTCGCCAGTCATTTTATGAAAGGTAGTGATTTTTATGAAGGAGTTCGCTCTTTATTGATTAATAAAGATAAAAAT
CCTCAATGGAGACCGTCCAGTTTGGAGTTGGTCACTGATGCCATGGTAGTGAGTTATTTTGAAAGCTCATCTTCCGGATT
GGAATTAATGATACTTTAG

Upstream 100 bases:

>100_bases
AAGCAATTCATTTTGCAAAAGTTTGCGCCACTGAAGATAAGAAGGAAGGAGTAGCTGCGTTTCTAGACAAGAGAACCGCG
GATTTTAAAGGGGTTTAATT

Downstream 100 bases:

>100_bases
TTTTTGGATTTTGATTGGGGGAATAATAGATTTCCCGTATGAATACTTCCTTATGGTTGAAAGCAGTCTGAAATATTATC
TGCTTGCTGTCATAAGGAAG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDNSIKAVVVQAVPGNAFCAGGDIRWLYNAGRSKDSE
QMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLHGSHPVASERFVFAMPETGIGFFPDIGASYLLNKCPGFLGV
YLGLTGNKLGPHDARKAGLVKQIVFAEQMQSMIEALKREDLSEDAFNLVDQCISSFASDAMPTEASQIKPLIDVCFSKPS
VELIRESLQSTDGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHFMKGSDFYEGVRSLLINKDKN
PQWRPSSLELVTDAMVVSYFESSSSGLELMIL

Sequences:

>Translated_352_residues
MTEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDNSIKAVVVQAVPGNAFCAGGDIRWLYNAGRSKDSE
QMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLHGSHPVASERFVFAMPETGIGFFPDIGASYLLNKCPGFLGV
YLGLTGNKLGPHDARKAGLVKQIVFAEQMQSMIEALKREDLSEDAFNLVDQCISSFASDAMPTEASQIKPLIDVCFSKPS
VELIRESLQSTDGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHFMKGSDFYEGVRSLLINKDKN
PQWRPSSLELVTDAMVVSYFESSSSGLELMIL
>Mature_351_residues
TEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDNSIKAVVVQAVPGNAFCAGGDIRWLYNAGRSKDSEQ
MQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLHGSHPVASERFVFAMPETGIGFFPDIGASYLLNKCPGFLGVY
LGLTGNKLGPHDARKAGLVKQIVFAEQMQSMIEALKREDLSEDAFNLVDQCISSFASDAMPTEASQIKPLIDVCFSKPSV
ELIRESLQSTDGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHFMKGSDFYEGVRSLLINKDKNP
QWRPSSLELVTDAMVVSYFESSSSGLELMIL

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=354, Percent_Identity=40.9604519774011, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI37594469, Length=310, Percent_Identity=40.3225806451613, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI194097323, Length=180, Percent_Identity=33.8888888888889, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1787659, Length=186, Percent_Identity=29.5698924731183, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI221142681, Length=216, Percent_Identity=24.0740740740741, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787660, Length=230, Percent_Identity=27.3913043478261, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=347, Percent_Identity=39.4812680115274, Blast_Score=240, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI25144157, Length=347, Percent_Identity=39.4812680115274, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI25145438, Length=186, Percent_Identity=29.5698924731183, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554946, Length=183, Percent_Identity=29.5081967213115, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=188, Percent_Identity=29.7872340425532, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=348, Percent_Identity=30.7471264367816, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571730, Length=350, Percent_Identity=40.8571428571429, Blast_Score=252, Evalue=2e-67,
Organism=Drosophila melanogaster, GI28571729, Length=350, Percent_Identity=40.8571428571429, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI20129971, Length=218, Percent_Identity=31.1926605504587, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24653477, Length=218, Percent_Identity=31.1926605504587, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 38854; Mature: 38723

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDNSIKAVVVQAVPGNA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCE
FCAGGDIRWLYNAGRSKDSEQMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLH
EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEE
GSHPVASERFVFAMPETGIGFFPDIGASYLLNKCPGFLGVYLGLTGNKLGPHDARKAGLV
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHH
KQIVFAEQMQSMIEALKREDLSEDAFNLVDQCISSFASDAMPTEASQIKPLIDVCFSKPS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
VELIRESLQSTDGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHF
HHHHHHHHHCCCCEEEEECCCHHHCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHH
MKGSDFYEGVRSLLINKDKNPQWRPSSLELVTDAMVVSYFESSSSGLELMIL
HCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
TEEVLFSQEGQLGFITLNRPKALNALTLTMIMALQKQLSIWKEDNSIKAVVVQAVPGNA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCE
FCAGGDIRWLYNAGRSKDSEQMQFFWHEYRLNHFIHHFGKPYISLLDGITMGGGVGISLH
EECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEEEE
GSHPVASERFVFAMPETGIGFFPDIGASYLLNKCPGFLGVYLGLTGNKLGPHDARKAGLV
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHH
KQIVFAEQMQSMIEALKREDLSEDAFNLVDQCISSFASDAMPTEASQIKPLIDVCFSKPS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
VELIRESLQSTDGVWALGVDNTLLQKSPLSLKITLAQIQKAKGLSLAECLKMDFDLASHF
HHHHHHHHHCCCCEEEEECCCHHHCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHH
MKGSDFYEGVRSLLINKDKNPQWRPSSLELVTDAMVVSYFESSSSGLELMIL
HCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA