BacMap

Definition	Legionella pneumophila str. Paris, complete genome.
Accession	NC_006368
Length	3,503,610

Click here to switch to the map view.

The map label for this gene is paaF [C]

Identifier: 54296891

GI number: 54296891

Start: 1036075

End: 1036851

Strand: Direct

Name: paaF [C]

Synonym: lpp0932

Alternate gene names: 54296891

Gene position: 1036075-1036851 (Clockwise)

Preceding gene: 54296890

Following gene: 54296892

Centisome position: 29.57

GC content: 41.44

Gene sequence:

>777_bases
ATGAATTTAATTGAACAGGATATAGATAATAACGGAATCTTAACTTTAACTTTGAATAGGCCAGAGAAGCTCAATGCTTT
AAGCACTGATGTTCTGAGCGCATTAAATGAATTATTCTTTCAAGCGAAATCCAATCCCAAAGTCAAAGCATTATTGTTAA
CAGGAAATGGTAAAGCATTTTGCGCTGGGGCTGACATTAATCGACTGGCTGAATGTAACGCTCAAACTGGTTATGAATTT
GCTTGCCAGGGACAAGAGGTTTTTCGACTTTTGGAAACGATGGGGAAACCTTCACTTGCCGCAGTGAATGGTTTTGCTTT
CGGTGGCGGATGTGAGTTAGCGATATCTGCGACTCTTAGAATTGCTTCAAATAAGGCAATGTTTGGTCAGCCTGAGGTAA
AATTAGGTGTTATTCCCGGGTATGGCGGCACACAACGATTGGCCAGGCTAATTGGCAAAGGGCGCGCGATGGATTTATGT
TTGACTGGGCGCTTTATAAATGCTGAGACTGCCTTAAACTGGGGGTTAGTCAGTGAAGTTGTAGCACCAGAGGATTTGTT
GACTCAAGGAAAAAATATTCTAAACGGAATATTAAGCATGGCTCCTTTAGCAGTTGCCAGTGTAATGGAAGTGATAGATC
ATGGTTATGATTTATCACTCACAGAGGCACTTCATTTGGAAGCAATTCATTTTGCAAAAGTTTGCGCCACTGAAGATAAG
AAGGAAGGAGTAGCTGCGTTTCTAGACAAGAGAACCGCGGATTTTAAAGGGGTTTAA

Upstream 100 bases:

>100_bases
CATCAAATTCTTGAAGGCACTAATGAAATCATGCGTGAAATTATAGCGAAAGCAAGTTTGGATGAAGAGTATTTTATAGA
GTAATCATAGGGGATTATTG

Downstream 100 bases:

>100_bases
TTATGACTGAAGAGGTGCTGTTTTCTCAGGAAGGTCAATTGGGATTCATTACTTTAAATCGACCAAAGGCTTTAAATGCT
TTAACTTTAACCATGATCAT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNLIEQDIDNNGILTLTLNRPEKLNALSTDVLSALNELFFQAKSNPKVKALLLTGNGKAFCAGADINRLAECNAQTGYEF
ACQGQEVFRLLETMGKPSLAAVNGFAFGGGCELAISATLRIASNKAMFGQPEVKLGVIPGYGGTQRLARLIGKGRAMDLC
LTGRFINAETALNWGLVSEVVAPEDLLTQGKNILNGILSMAPLAVASVMEVIDHGYDLSLTEALHLEAIHFAKVCATEDK
KEGVAAFLDKRTADFKGV

Sequences:

>Translated_258_residues
MNLIEQDIDNNGILTLTLNRPEKLNALSTDVLSALNELFFQAKSNPKVKALLLTGNGKAFCAGADINRLAECNAQTGYEF
ACQGQEVFRLLETMGKPSLAAVNGFAFGGGCELAISATLRIASNKAMFGQPEVKLGVIPGYGGTQRLARLIGKGRAMDLC
LTGRFINAETALNWGLVSEVVAPEDLLTQGKNILNGILSMAPLAVASVMEVIDHGYDLSLTEALHLEAIHFAKVCATEDK
KEGVAAFLDKRTADFKGV
>Mature_258_residues
MNLIEQDIDNNGILTLTLNRPEKLNALSTDVLSALNELFFQAKSNPKVKALLLTGNGKAFCAGADINRLAECNAQTGYEF
ACQGQEVFRLLETMGKPSLAAVNGFAFGGGCELAISATLRIASNKAMFGQPEVKLGVIPGYGGTQRLARLIGKGRAMDLC
LTGRFINAETALNWGLVSEVVAPEDLLTQGKNILNGILSMAPLAVASVMEVIDHGYDLSLTEALHLEAIHFAKVCATEDK
KEGVAAFLDKRTADFKGV

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=40.9448818897638, Blast_Score=185, Evalue=3e-47,
Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=39.7727272727273, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI4502327, Length=254, Percent_Identity=31.496062992126, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI68989263, Length=172, Percent_Identity=37.7906976744186, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI70995211, Length=252, Percent_Identity=29.3650793650794, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI150378541, Length=253, Percent_Identity=31.2252964426877, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI31542718, Length=243, Percent_Identity=29.6296296296296, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI157694516, Length=228, Percent_Identity=27.1929824561404, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI213417737, Length=228, Percent_Identity=27.1929824561404, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI37594471, Length=199, Percent_Identity=30.6532663316583, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI37594469, Length=199, Percent_Identity=30.6532663316583, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI261878539, Length=77, Percent_Identity=50.6493506493506, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157694520, Length=183, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=40.080971659919, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=34.3873517786561, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=33.8645418326693, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790281, Length=237, Percent_Identity=32.0675105485232, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788682, Length=185, Percent_Identity=37.2972972972973, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=29.296875, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=29.2307692307692, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=37.1541501976285, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=37.8600823045267, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17540714, Length=226, Percent_Identity=32.7433628318584, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17558304, Length=163, Percent_Identity=38.6503067484663, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17560910, Length=172, Percent_Identity=36.046511627907, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17536985, Length=263, Percent_Identity=25.0950570342205, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=257, Percent_Identity=24.5136186770428, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25144276, Length=165, Percent_Identity=37.5757575757576, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=165, Percent_Identity=37.5757575757576, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17508951, Length=165, Percent_Identity=37.5757575757576, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144160, Length=207, Percent_Identity=31.8840579710145, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25144157, Length=207, Percent_Identity=31.8840579710145, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=29.3436293436293, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25141363, Length=227, Percent_Identity=27.7533039647577, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=245, Percent_Identity=22.8571428571429, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=205, Percent_Identity=28.2926829268293, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320241, Length=185, Percent_Identity=32.4324324324324, Blast_Score=82, Evalue=6e-17,
Organism=Drosophila melanogaster, GI20129971, Length=242, Percent_Identity=41.7355371900826, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24653477, Length=242, Percent_Identity=41.7355371900826, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24653139, Length=261, Percent_Identity=31.8007662835249, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=26.6129032258064, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19920382, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583077, Length=178, Percent_Identity=37.0786516853933, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24583079, Length=178, Percent_Identity=37.0786516853933, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI19921000, Length=178, Percent_Identity=37.0786516853933, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650670, Length=265, Percent_Identity=30.5660377358491, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357171, Length=181, Percent_Identity=29.8342541436464, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28571729, Length=301, Percent_Identity=25.9136212624585, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI28571730, Length=301, Percent_Identity=25.9136212624585, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583165, Length=176, Percent_Identity=32.3863636363636, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19921018, Length=177, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27503; Mature: 27503

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIEQDIDNNGILTLTLNRPEKLNALSTDVLSALNELFFQAKSNPKVKALLLTGNGKAF
CCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEE
CAGADINRLAECNAQTGYEFACQGQEVFRLLETMGKPSLAAVNGFAFGGGCELAISATLR
EECCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCEEEECCEEECCCCEEEEEEEEE
IASNKAMFGQPEVKLGVIPGYGGTQRLARLIGKGRAMDLCLTGRFINAETALNWGLVSEV
EECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCEECHHHHHCHHHHHHH
VAPEDLLTQGKNILNGILSMAPLAVASVMEVIDHGYDLSLTEALHLEAIHFAKVCATEDK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCH
KEGVAAFLDKRTADFKGV
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNLIEQDIDNNGILTLTLNRPEKLNALSTDVLSALNELFFQAKSNPKVKALLLTGNGKAF
CCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEE
CAGADINRLAECNAQTGYEFACQGQEVFRLLETMGKPSLAAVNGFAFGGGCELAISATLR
EECCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCEEEECCEEECCCCEEEEEEEEE
IASNKAMFGQPEVKLGVIPGYGGTQRLARLIGKGRAMDLCLTGRFINAETALNWGLVSEV
EECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCEECHHHHHCHHHHHHH
VAPEDLLTQGKNILNGILSMAPLAVASVMEVIDHGYDLSLTEALHLEAIHFAKVCATEDK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCH
KEGVAAFLDKRTADFKGV
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA