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The map label for this gene is glsA1 [H]

Identifier: 54295835

GI number: 54295835

Start: 3335834

End: 3337999

Strand: Reverse

Name: glsA1 [H]

Synonym: lpl2926

Alternate gene names: 54295835

Gene position: 3337999-3335834 (Counterclockwise)

Preceding gene: 54295837

Following gene: 54295832

Centisome position: 99.77

GC content: 34.53

Gene sequence:

>2166_bases
ATGACTCGAAGTCAATTGATTTTGGCTATTTTGGCAGGATTGGTCATAAGTATTGACAATATGATTAGTATTGTTGCGTT
TTCCTCGCTTATTTACCAAGGTGCGTTAGAAATTTATATTCCGTTGGTCATTAATATATTGGCAATTTCAGTAATTATTA
TAAGCGCCAGCTATTTGTTCATGTCTTCCCCTCCTTATGCAATCGCTCAGTTGCAAGATGAAGCGGCAATTTTGTATTCA
GCCATGGGTTTAGTGATAATTAAGTCGATGCCATCAAGTTCTACGAATGAAGCCATCTTTATTACGGTTCTCTTTATGCT
TGGAGTCACTACCTGTTTAACGGGCTTATCATTCTACTTCGTTGGAAAATTTAGGTTTGGAAATATTATCCGTTATCTGC
CATATCCTGTGATTTGTGGTTTTATGGCAGCGACAGGCTGGCTAGTTTTATCAGGAACATTTGCATTATTAACTGGTAAA
GCGCTGCATCAGAATTGGCTTGTTTTTTTTCATAAAGAGGAAATATTATTGTGGGCTCCAGGTTTTATTGCGGGAATAGT
TGTTTATATTTTTAAAGAAAAATTAGGTTATCGATACGCGCTTCAATTGATGTTTATTTCTCTTGTAATTCTATTCTATG
CTCTTTTTTATATTTTTAATTTGGAGTATTTGGTCGATCCAACGGAAGGGTACGTCTTGGGACCTTTCAATCAAAGCCAT
ATTGATTCGCTCATGAAACCTGAAATATGGCAAATGATTCATTATCCATTCTCAATGACCCTATTGAATTACATAGGGTT
AGTTATACTGGTAAGTTTTATTGCCTTGTTATTAAACGCAAGCAGTTATGAATTAATAGTTAATAAGCAATTGGATTTAA
ACAAGGAACTTCGTATAGCAGGTATTGGCAATGTATTCAGTGGATTACTTGGAGGAATGGTTGGCTATTTGTCTTTGTCA
GCGTCCACTGTTGCAAAAGAGTATGGCGGTGCTCGTATTATAGGGGTGATGGCTTTCGTTCCCATGTTGCTTATTTTGTG
CTTTGGTGCTGTGGTCGTTGAATGTTTCCCGAAAATGGCTATCGGCTGTTATTTGTTTTATATCGCTTTTTGCTTTCTAT
CTGAATGGTTGATCAATACCTGGCGTTTATTAAATTTAAGTGAATATTTAATCGTTTTACTGATATTGGTTATTGCTATT
GTCTTTAATATGATTACGGCGGTTGCTATAGGAACGGTTATTTCAATTTTTATCTTCGCTTTTCGCTACAGCAAAATAAA
TCCGGTTAAGTATTTGTTTTCCGGAGCAGATTATAATTCTTCTTTTGAGAGAAATCCTATATCTCAATCTATTTTATCGA
CACAGGGAGATGAAATTCAGTTTTTGAAGTTGCAAGGATTTCTTTTTTTTGGCTCTATTTACAGGCTGCTTCAGTTAATA
AAAAATATACAGAAGGCTCGATATATCATTTTAGACTTTGAGCTTGTCTACAATATCGACTCATCCCGCATTATTTTAAT
GAAAAACTTAAAGCTCCATGCGGAAAAGAATAATATTTCCTTTGCAATTTGTTCATTAAAGCCCATTGTTTATCATGAAT
TAATGAAAACCAATTTATTACAATCGAAAACCAATTGGCTTAAAGTCTTTACTGATCAAGAATCAGCTTTAGAGTGGTGT
GAAGATCAAGTTATAGAAAAATATACAGAAAATATAAATATTGAAGAAGTAACACTTGAGAAACAGTTACACTATTTAGG
TTTTTCCTCTGAACTGGTAGCATGGATTAGTGAAAAGGCTTCTATAAAACCTTATAACTCTGATGATATCATTTGTCATG
AAGGAGAAGAGTCAAACAGTGTTTACTTTATTCATCGGGGAAGAGTTACAGCATTTGTCGGTGATAAACGTGTACTTGTT
GTGGGTTCAGGTAATGTACTTGGTGAAATTGCCATCTACACTCATAAGAAGCGCACAGCAACATTAAAAACCAATGAAAA
AACCATTGTTTATGAAATTGATTTGAAATCAATCCAAGAGCTTTCTAAAAATAAACCCCTACTCTTGGTTCAATTTCACG
CATGTATGGCTAAAATTTTGGCAAATCGTCTCTCGGTACTAAATAAACGGATAAAAGTTTTTGATTCCACCGCCATATTG
CAATAA

Upstream 100 bases:

>100_bases
GGACTGCTATTTTAATTCGATCAGAAATGTGAAAAACTGGATTTTTCTGTTGTTTAGTAAAATAATCCTTTGGTTTTGAA
ATGAATGAGTGAGAGATAGG

Downstream 100 bases:

>100_bases
AAGTTAATAAAATATTCTTTTACTGTGAAATAATAATTAATAAGGAACAACGTTTTAAAGTTGTTCCAATTGTCTTAACT
GAATTCGATAGGCAACAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 720

Protein sequence:

>721_residues
MTRSQLILAILAGLVISIDNMISIVAFSSLIYQGALEIYIPLVINILAISVIIISASYLFMSSPPYAIAQLQDEAAILYS
AMGLVIIKSMPSSSTNEAIFITVLFMLGVTTCLTGLSFYFVGKFRFGNIIRYLPYPVICGFMAATGWLVLSGTFALLTGK
ALHQNWLVFFHKEEILLWAPGFIAGIVVYIFKEKLGYRYALQLMFISLVILFYALFYIFNLEYLVDPTEGYVLGPFNQSH
IDSLMKPEIWQMIHYPFSMTLLNYIGLVILVSFIALLLNASSYELIVNKQLDLNKELRIAGIGNVFSGLLGGMVGYLSLS
ASTVAKEYGGARIIGVMAFVPMLLILCFGAVVVECFPKMAIGCYLFYIAFCFLSEWLINTWRLLNLSEYLIVLLILVIAI
VFNMITAVAIGTVISIFIFAFRYSKINPVKYLFSGADYNSSFERNPISQSILSTQGDEIQFLKLQGFLFFGSIYRLLQLI
KNIQKARYIILDFELVYNIDSSRIILMKNLKLHAEKNNISFAICSLKPIVYHELMKTNLLQSKTNWLKVFTDQESALEWC
EDQVIEKYTENINIEEVTLEKQLHYLGFSSELVAWISEKASIKPYNSDDIICHEGEESNSVYFIHRGRVTAFVGDKRVLV
VGSGNVLGEIAIYTHKKRTATLKTNEKTIVYEIDLKSIQELSKNKPLLLVQFHACMAKILANRLSVLNKRIKVFDSTAIL
Q

Sequences:

>Translated_721_residues
MTRSQLILAILAGLVISIDNMISIVAFSSLIYQGALEIYIPLVINILAISVIIISASYLFMSSPPYAIAQLQDEAAILYS
AMGLVIIKSMPSSSTNEAIFITVLFMLGVTTCLTGLSFYFVGKFRFGNIIRYLPYPVICGFMAATGWLVLSGTFALLTGK
ALHQNWLVFFHKEEILLWAPGFIAGIVVYIFKEKLGYRYALQLMFISLVILFYALFYIFNLEYLVDPTEGYVLGPFNQSH
IDSLMKPEIWQMIHYPFSMTLLNYIGLVILVSFIALLLNASSYELIVNKQLDLNKELRIAGIGNVFSGLLGGMVGYLSLS
ASTVAKEYGGARIIGVMAFVPMLLILCFGAVVVECFPKMAIGCYLFYIAFCFLSEWLINTWRLLNLSEYLIVLLILVIAI
VFNMITAVAIGTVISIFIFAFRYSKINPVKYLFSGADYNSSFERNPISQSILSTQGDEIQFLKLQGFLFFGSIYRLLQLI
KNIQKARYIILDFELVYNIDSSRIILMKNLKLHAEKNNISFAICSLKPIVYHELMKTNLLQSKTNWLKVFTDQESALEWC
EDQVIEKYTENINIEEVTLEKQLHYLGFSSELVAWISEKASIKPYNSDDIICHEGEESNSVYFIHRGRVTAFVGDKRVLV
VGSGNVLGEIAIYTHKKRTATLKTNEKTIVYEIDLKSIQELSKNKPLLLVQFHACMAKILANRLSVLNKRIKVFDSTAIL
Q
>Mature_720_residues
TRSQLILAILAGLVISIDNMISIVAFSSLIYQGALEIYIPLVINILAISVIIISASYLFMSSPPYAIAQLQDEAAILYSA
MGLVIIKSMPSSSTNEAIFITVLFMLGVTTCLTGLSFYFVGKFRFGNIIRYLPYPVICGFMAATGWLVLSGTFALLTGKA
LHQNWLVFFHKEEILLWAPGFIAGIVVYIFKEKLGYRYALQLMFISLVILFYALFYIFNLEYLVDPTEGYVLGPFNQSHI
DSLMKPEIWQMIHYPFSMTLLNYIGLVILVSFIALLLNASSYELIVNKQLDLNKELRIAGIGNVFSGLLGGMVGYLSLSA
STVAKEYGGARIIGVMAFVPMLLILCFGAVVVECFPKMAIGCYLFYIAFCFLSEWLINTWRLLNLSEYLIVLLILVIAIV
FNMITAVAIGTVISIFIFAFRYSKINPVKYLFSGADYNSSFERNPISQSILSTQGDEIQFLKLQGFLFFGSIYRLLQLIK
NIQKARYIILDFELVYNIDSSRIILMKNLKLHAEKNNISFAICSLKPIVYHELMKTNLLQSKTNWLKVFTDQESALEWCE
DQVIEKYTENINIEEVTLEKQLHYLGFSSELVAWISEKASIKPYNSDDIICHEGEESNSVYFIHRGRVTAFVGDKRVLVV
GSGNVLGEIAIYTHKKRTATLKTNEKTIVYEIDLKSIQELSKNKPLLLVQFHACMAKILANRLSVLNKRIKVFDSTAILQ

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321564, Length=564, Percent_Identity=26.063829787234, Blast_Score=147, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR015868
- InterPro:   IPR014710
- InterPro:   IPR002645 [H]

Pfam domain/function: PF00027 cNMP_binding; PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 81386; Mature: 81254

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3 ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSQLILAILAGLVISIDNMISIVAFSSLIYQGALEIYIPLVINILAISVIIISASYLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
MSSPPYAIAQLQDEAAILYSAMGLVIIKSMPSSSTNEAIFITVLFMLGVTTCLTGLSFYF
ECCCCHHHHHHCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGKFRFGNIIRYLPYPVICGFMAATGWLVLSGTFALLTGKALHQNWLVFFHKEEILLWAP
EEEHHHCCHHHHCCHHHHHHHHHHCCHHHEECHHHHHCCHHHHCCEEEEEEECEEEEECC
GFIAGIVVYIFKEKLGYRYALQLMFISLVILFYALFYIFNLEYLVDPTEGYVLGPFNQSH
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCEEECCCCHHH
IDSLMKPEIWQMIHYPFSMTLLNYIGLVILVSFIALLLNASSYELIVNKQLDLNKELRIA
HHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEE
GIGNVFSGLLGGMVGYLSLSASTVAKEYGGARIIGVMAFVPMLLILCFGAVVVECFPKMA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGCYLFYIAFCFLSEWLINTWRLLNLSEYLIVLLILVIAIVFNMITAVAIGTVISIFIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRYSKINPVKYLFSGADYNSSFERNPISQSILSTQGDEIQFLKLQGFLFFGSIYRLLQLI
HHCCCCCHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHH
KNIQKARYIILDFELVYNIDSSRIILMKNLKLHAEKNNISFAICSLKPIVYHELMKTNLL
HHHHHCEEEEEEEEEEEECCCCEEEEEECCEEEEECCCCEEEEEECCHHHHHHHHHHHHH
QSKTNWLKVFTDQESALEWCEDQVIEKYTENINIEEVTLEKQLHYLGFSSELVAWISEKA
HCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCHHHHHHHHCCC
SIKPYNSDDIICHEGEESNSVYFIHRGRVTAFVGDKRVLVVGSGNVLGEIAIYTHKKRTA
CCCCCCCCCEEEECCCCCCCEEEEECCEEEEEECCCEEEEEECCCCEEEEEEEEECCCEE
TLKTNEKTIVYEIDLKSIQELSKNKPLLLVQFHACMAKILANRLSVLNKRIKVFDSTAIL
EEECCCEEEEEEECHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
Q
C
>Mature Secondary Structure 
TRSQLILAILAGLVISIDNMISIVAFSSLIYQGALEIYIPLVINILAISVIIISASYLF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
MSSPPYAIAQLQDEAAILYSAMGLVIIKSMPSSSTNEAIFITVLFMLGVTTCLTGLSFYF
ECCCCHHHHHHCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGKFRFGNIIRYLPYPVICGFMAATGWLVLSGTFALLTGKALHQNWLVFFHKEEILLWAP
EEEHHHCCHHHHCCHHHHHHHHHHCCHHHEECHHHHHCCHHHHCCEEEEEEECEEEEECC
GFIAGIVVYIFKEKLGYRYALQLMFISLVILFYALFYIFNLEYLVDPTEGYVLGPFNQSH
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCEEECCCCHHH
IDSLMKPEIWQMIHYPFSMTLLNYIGLVILVSFIALLLNASSYELIVNKQLDLNKELRIA
HHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEE
GIGNVFSGLLGGMVGYLSLSASTVAKEYGGARIIGVMAFVPMLLILCFGAVVVECFPKMA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGCYLFYIAFCFLSEWLINTWRLLNLSEYLIVLLILVIAIVFNMITAVAIGTVISIFIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRYSKINPVKYLFSGADYNSSFERNPISQSILSTQGDEIQFLKLQGFLFFGSIYRLLQLI
HHCCCCCHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHH
KNIQKARYIILDFELVYNIDSSRIILMKNLKLHAEKNNISFAICSLKPIVYHELMKTNLL
HHHHHCEEEEEEEEEEEECCCCEEEEEECCEEEEECCCCEEEEEECCHHHHHHHHHHHHH
QSKTNWLKVFTDQESALEWCEDQVIEKYTENINIEEVTLEKQLHYLGFSSELVAWISEKA
HCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCHHHHHHHHCCC
SIKPYNSDDIICHEGEESNSVYFIHRGRVTAFVGDKRVLVVGSGNVLGEIAIYTHKKRTA
CCCCCCCCCEEEECCCCCCCEEEEECCEEEEEECCCEEEEEECCCCEEEEEEEEECCCEE
TLKTNEKTIVYEIDLKSIQELSKNKPLLLVQFHACMAKILANRLSVLNKRIKVFDSTAIL
EEECCCEEEEEEECHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]