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The map label for this gene is nuoG [H]

Identifier: 54295612

GI number: 54295612

Start: 3079785

End: 3082136

Strand: Reverse

Name: nuoG [H]

Synonym: lpl2699

Alternate gene names: 54295612

Gene position: 3082136-3079785 (Counterclockwise)

Preceding gene: 54295613

Following gene: 54295611

Centisome position: 92.12

GC content: 41.37

Gene sequence:

>2352_bases
ATGGCTACTATTGAAATCGACGGTAAAACATTTGAAGCAGAAAACGGTAAAATGATTATAGAGGTTGCTGATGAGGCGGG
CATCTATATTCCACGTTTTTGCTATCATAAAAAATTATCTGTGGCAGCTAATTGCCGCATGTGTTTGGTCGAAGTGGAAA
ATGGGAGAAAACCGGTTCCTGCTTGCGCTACACCTATAACTAATGGGATGAAAGTATTTACAAAGTCAGAGCAGGCTATA
CACTCCCAAAAGGTAGTGATGGAATTTCTCTTGATAAATCATCCTTTGGATTGTCCTATCTGTGATCAGGGTGGAGAATG
TGAGCTTCAAGATATTTCTATGGGGTTTGGCGCTGATAAATCAGAGTATACAGAAAGCAAGCGTGCGGTAGACGATGAGA
ATTTAGGAACGCTAATATCTACTGAAATGACACGTTGCATTCATTGCACACGCTGTGTACGCTTCGGCGAGGAAATTGCA
GGGGTAAGAGAGCTGGGAGCTACCGGCCGTGGCGAAAAGACGCAGATTGGTACTTATGTAGAACACAGTATGACATCGGA
GGTTTCAGGGAATATCATAGACTTGTGCCCTGTTGGTGCTTTAACTTCCAAGCCTTATCGGTTTAAAGCCCGGGCATGGG
AATTGACTCAAAATGACAGTGTTGCGCCACATGATTGCCTGGGGTCAAATGTTCATATTCATACAAGAAATAATAAATTA
ATGCGTGTAGTTCCCAGGGAGAACGAATCTATCAACGAAACCTGGCTTTCAGACCGAGATAGATTTAGCTATTTGGGGTT
AAATGCGGCTTCAAGGGCGAGCAAACCACAAATCAAAAAAAATGGCCAATGGGAAGCGGTTGATTGGGAAACCGCACTTA
AGTTTGCGGCAGAAGGGATAAGCCGAGTTATCAAACAACATGGCCCAGAGCAAATGGCCGCTTTTGCGTCCAGTTCTTCT
ACCCTGGAAGAAATGTATTTACTACAAAAATTAATGAGAGAGTTAGGTGTTCAAAATCTAGATCACCGGTTACAACAAAT
TGATTTTAGAGATCAGGCATTTTTACCTACTACGCCAGTAAGCACTTTGCCTTACGCAGAGATAGATCATCAGAATTCAA
TTCTGTTAATAGGATGTAATATTCATAGAGAAGTACCGTTGGCAGGAACAAGGGTAAGAAAAGCTTTTCGCAATGGCGCA
AAAATTTATGCCCTTAATCCAGTAGATTTTGATTATCATTTTGATTTGTCCGGACGAGTCATTATTTCTCCTTTGGAAAT
GCCGATGCAATTAGCTAAATTAGCCTTAGCGCTTACAACCGAATTGGCATTGCTTCCAGAAGAAGTTCAAAAACTGTTAA
TAGGTTTGGAAGTAGACAAACAAACCAAACAAATAGCACAATCATTAAAAGAAGAGAAAGCCTGTTTGATAACCGGAGCA
ATAGTTGAAAATCATCCTGAAGCTTCCTTATTGCGTACTTTGGTCGCTATTGTTCAAAAACTTAGTGGAGCCAAATTAGT
CAGGTTAACGACTGGAGCAAACAGCGCGGGCGCATGTATTGCAGGTATGCTGCCGCATAGAACAGTTGCTGGGAAATCAA
TTGCAGAGCCGGGTTTCAATGTACAAGAAGCGTTAAATTCCAAGTTAAAAGGTTATTTACTCATGGGTGTTGAGCCAGGC
TATGATTTTGCAAATCCAGCCGGGGCAAGGCAATCAATGTTAGCTGCAGAGTTTGTTGTACTCTTATCAGCCTATGAGCA
TGAATCCATGCATGATTATGCAGATGTTATTTTACCGATCGCTCCTTATACTGAAACATCTGGAACATACATAAACATTG
ATAATACCTGGCAAACAGTAAAAGGAGTCATGTTACCATTCGGCGAATCACGGCCAGCCTGGAAGGTGCTTCGTGTTTTG
GGTAATTTATTGCACTGCAAAAAATTTGATTATACCTCAACAGAGGACATCTTGGAGGAAGTCAAAGAAGCAGTATCGAT
GACAATGGAGCACGAATACGAACCTTACTACCCTGAATCATTGCCTGTCATTAATCAATCACTGGTAAGAGTTGGAGAGT
GGCCTCTTTATCGAATAGATGCTATTACTAGAAATGCAAAAGAGTTACAATTATGTGCCGCATCAGAATCTGCCTGTATA
AGAATTCATCCATCAACTGCAGATAGATTGAAATTAGAAGAAATTGCTACTGTATCTCAAGGAGATATTGAGATAACATT
GCCGCTAAAACGTGATGAGCGCATTGCGGTTGATGTTGTGTGGGTGGCAAATGCAATGCCAGAAACAGTTGACCTTGGTC
ACTCGTTTGCTGCAATAACAATAAAGCGCTAG

Upstream 100 bases:

>100_bases
TGGCCAGTACAGAGTTTTGTTAAACATTTCTATGATGAATTTGAATATTTCATAAAGCATAAACGCTCGATCGTCGCAGC
ATAATTAAGAAGGTTAGACC

Downstream 100 bases:

>100_bases
AAAGGTATAAAAATGCTTCATACTATTGGCATACTAATTTGGATTATTATTAAAATTATTGTGATAGTTGTCCCTTTACT
GATTTCCGTGGCCTACCTAA

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MATIEIDGKTFEAENGKMIIEVADEAGIYIPRFCYHKKLSVAANCRMCLVEVENGRKPVPACATPITNGMKVFTKSEQAI
HSQKVVMEFLLINHPLDCPICDQGGECELQDISMGFGADKSEYTESKRAVDDENLGTLISTEMTRCIHCTRCVRFGEEIA
GVRELGATGRGEKTQIGTYVEHSMTSEVSGNIIDLCPVGALTSKPYRFKARAWELTQNDSVAPHDCLGSNVHIHTRNNKL
MRVVPRENESINETWLSDRDRFSYLGLNAASRASKPQIKKNGQWEAVDWETALKFAAEGISRVIKQHGPEQMAAFASSSS
TLEEMYLLQKLMRELGVQNLDHRLQQIDFRDQAFLPTTPVSTLPYAEIDHQNSILLIGCNIHREVPLAGTRVRKAFRNGA
KIYALNPVDFDYHFDLSGRVIISPLEMPMQLAKLALALTTELALLPEEVQKLLIGLEVDKQTKQIAQSLKEEKACLITGA
IVENHPEASLLRTLVAIVQKLSGAKLVRLTTGANSAGACIAGMLPHRTVAGKSIAEPGFNVQEALNSKLKGYLLMGVEPG
YDFANPAGARQSMLAAEFVVLLSAYEHESMHDYADVILPIAPYTETSGTYINIDNTWQTVKGVMLPFGESRPAWKVLRVL
GNLLHCKKFDYTSTEDILEEVKEAVSMTMEHEYEPYYPESLPVINQSLVRVGEWPLYRIDAITRNAKELQLCAASESACI
RIHPSTADRLKLEEIATVSQGDIEITLPLKRDERIAVDVVWVANAMPETVDLGHSFAAITIKR

Sequences:

>Translated_783_residues
MATIEIDGKTFEAENGKMIIEVADEAGIYIPRFCYHKKLSVAANCRMCLVEVENGRKPVPACATPITNGMKVFTKSEQAI
HSQKVVMEFLLINHPLDCPICDQGGECELQDISMGFGADKSEYTESKRAVDDENLGTLISTEMTRCIHCTRCVRFGEEIA
GVRELGATGRGEKTQIGTYVEHSMTSEVSGNIIDLCPVGALTSKPYRFKARAWELTQNDSVAPHDCLGSNVHIHTRNNKL
MRVVPRENESINETWLSDRDRFSYLGLNAASRASKPQIKKNGQWEAVDWETALKFAAEGISRVIKQHGPEQMAAFASSSS
TLEEMYLLQKLMRELGVQNLDHRLQQIDFRDQAFLPTTPVSTLPYAEIDHQNSILLIGCNIHREVPLAGTRVRKAFRNGA
KIYALNPVDFDYHFDLSGRVIISPLEMPMQLAKLALALTTELALLPEEVQKLLIGLEVDKQTKQIAQSLKEEKACLITGA
IVENHPEASLLRTLVAIVQKLSGAKLVRLTTGANSAGACIAGMLPHRTVAGKSIAEPGFNVQEALNSKLKGYLLMGVEPG
YDFANPAGARQSMLAAEFVVLLSAYEHESMHDYADVILPIAPYTETSGTYINIDNTWQTVKGVMLPFGESRPAWKVLRVL
GNLLHCKKFDYTSTEDILEEVKEAVSMTMEHEYEPYYPESLPVINQSLVRVGEWPLYRIDAITRNAKELQLCAASESACI
RIHPSTADRLKLEEIATVSQGDIEITLPLKRDERIAVDVVWVANAMPETVDLGHSFAAITIKR
>Mature_782_residues
ATIEIDGKTFEAENGKMIIEVADEAGIYIPRFCYHKKLSVAANCRMCLVEVENGRKPVPACATPITNGMKVFTKSEQAIH
SQKVVMEFLLINHPLDCPICDQGGECELQDISMGFGADKSEYTESKRAVDDENLGTLISTEMTRCIHCTRCVRFGEEIAG
VRELGATGRGEKTQIGTYVEHSMTSEVSGNIIDLCPVGALTSKPYRFKARAWELTQNDSVAPHDCLGSNVHIHTRNNKLM
RVVPRENESINETWLSDRDRFSYLGLNAASRASKPQIKKNGQWEAVDWETALKFAAEGISRVIKQHGPEQMAAFASSSST
LEEMYLLQKLMRELGVQNLDHRLQQIDFRDQAFLPTTPVSTLPYAEIDHQNSILLIGCNIHREVPLAGTRVRKAFRNGAK
IYALNPVDFDYHFDLSGRVIISPLEMPMQLAKLALALTTELALLPEEVQKLLIGLEVDKQTKQIAQSLKEEKACLITGAI
VENHPEASLLRTLVAIVQKLSGAKLVRLTTGANSAGACIAGMLPHRTVAGKSIAEPGFNVQEALNSKLKGYLLMGVEPGY
DFANPAGARQSMLAAEFVVLLSAYEHESMHDYADVILPIAPYTETSGTYINIDNTWQTVKGVMLPFGESRPAWKVLRVLG
NLLHCKKFDYTSTEDILEEVKEAVSMTMEHEYEPYYPESLPVINQSLVRVGEWPLYRIDAITRNAKELQLCAASESACIR
IHPSTADRLKLEEIATVSQGDIEITLPLKRDERIAVDVVWVANAMPETVDLGHSFAAITIKR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=748, Percent_Identity=34.7593582887701, Blast_Score=409, Evalue=1e-114,
Organism=Escherichia coli, GI145693161, Length=701, Percent_Identity=26.3908701854494, Blast_Score=224, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17565758, Length=700, Percent_Identity=35.2857142857143, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI32566231, Length=630, Percent_Identity=36.8253968253968, Blast_Score=364, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI193209088, Length=247, Percent_Identity=54.6558704453441, Blast_Score=292, Evalue=6e-79,
Organism=Drosophila melanogaster, GI24640559, Length=678, Percent_Identity=37.0206489675516, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24640557, Length=678, Percent_Identity=37.0206489675516, Blast_Score=392, Evalue=1e-109,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 86859; Mature: 86727

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIEIDGKTFEAENGKMIIEVADEAGIYIPRFCYHKKLSVAANCRMCLVEVENGRKPVP
CEEEEECCCEEECCCCEEEEEECCCCCCCCCHHHHHCCHHEECCCEEEEEEECCCCCCCC
ACATPITNGMKVFTKSEQAIHSQKVVMEFLLINHPLDCPICDQGGECELQDISMGFGADK
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCH
SEYTESKRAVDDENLGTLISTEMTRCIHCTRCVRFGEEIAGVRELGATGRGEKTQIGTYV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EHSMTSEVSGNIIDLCPVGALTSKPYRFKARAWELTQNDSVAPHDCLGSNVHIHTRNNKL
HHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCHHHCCCCEEEEECCCCE
MRVVPRENESINETWLSDRDRFSYLGLNAASRASKPQIKKNGQWEAVDWETALKFAAEGI
EEEECCCCCCCCHHHCCCCCCEEEECCCHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
SRVIKQHGPEQMAAFASSSSTLEEMYLLQKLMRELGVQNLDHRLQQIDFRDQAFLPTTPV
HHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
STLPYAEIDHQNSILLIGCNIHREVPLAGTRVRKAFRNGAKIYALNPVDFDYHFDLSGRV
CCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEECCCCCE
IISPLEMPMQLAKLALALTTELALLPEEVQKLLIGLEVDKQTKQIAQSLKEEKACLITGA
EECCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEH
IVENHPEASLLRTLVAIVQKLSGAKLVRLTTGANSAGACIAGMLPHRTVAGKSIAEPGFN
HHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
VQEALNSKLKGYLLMGVEPGYDFANPAGARQSMLAAEFVVLLSAYEHESMHDYADVILPI
HHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEC
APYTETSGTYINIDNTWQTVKGVMLPFGESRPAWKVLRVLGNLLHCKKFDYTSTEDILEE
CCCCCCCCCEEEECCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VKEAVSMTMEHEYEPYYPESLPVINQSLVRVGEWPLYRIDAITRNAKELQLCAASESACI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHCCHHHHEEEECCCCCEE
RIHPSTADRLKLEEIATVSQGDIEITLPLKRDERIAVDVVWVANAMPETVDLGHSFAAIT
EECCCCCHHEEHHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCHHHCCCCEEEEE
IKR
EEC
>Mature Secondary Structure 
ATIEIDGKTFEAENGKMIIEVADEAGIYIPRFCYHKKLSVAANCRMCLVEVENGRKPVP
EEEEECCCEEECCCCEEEEEECCCCCCCCCHHHHHCCHHEECCCEEEEEEECCCCCCCC
ACATPITNGMKVFTKSEQAIHSQKVVMEFLLINHPLDCPICDQGGECELQDISMGFGADK
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCH
SEYTESKRAVDDENLGTLISTEMTRCIHCTRCVRFGEEIAGVRELGATGRGEKTQIGTYV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EHSMTSEVSGNIIDLCPVGALTSKPYRFKARAWELTQNDSVAPHDCLGSNVHIHTRNNKL
HHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCHHHCCCCEEEEECCCCE
MRVVPRENESINETWLSDRDRFSYLGLNAASRASKPQIKKNGQWEAVDWETALKFAAEGI
EEEECCCCCCCCHHHCCCCCCEEEECCCHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHH
SRVIKQHGPEQMAAFASSSSTLEEMYLLQKLMRELGVQNLDHRLQQIDFRDQAFLPTTPV
HHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
STLPYAEIDHQNSILLIGCNIHREVPLAGTRVRKAFRNGAKIYALNPVDFDYHFDLSGRV
CCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEECCCCCE
IISPLEMPMQLAKLALALTTELALLPEEVQKLLIGLEVDKQTKQIAQSLKEEKACLITGA
EECCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEH
IVENHPEASLLRTLVAIVQKLSGAKLVRLTTGANSAGACIAGMLPHRTVAGKSIAEPGFN
HHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
VQEALNSKLKGYLLMGVEPGYDFANPAGARQSMLAAEFVVLLSAYEHESMHDYADVILPI
HHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEC
APYTETSGTYINIDNTWQTVKGVMLPFGESRPAWKVLRVLGNLLHCKKFDYTSTEDILEE
CCCCCCCCCEEEECCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VKEAVSMTMEHEYEPYYPESLPVINQSLVRVGEWPLYRIDAITRNAKELQLCAASESACI
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEHHHHCCHHHHEEEECCCCCEE
RIHPSTADRLKLEEIATVSQGDIEITLPLKRDERIAVDVVWVANAMPETVDLGHSFAAIT
EECCCCCHHEEHHHHHCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCHHHCCCCEEEEE
IKR
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]