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The map label for this gene is nuoH [H]

Identifier: 54295611

GI number: 54295611

Start: 3078750

End: 3079772

Strand: Reverse

Name: nuoH [H]

Synonym: lpl2698

Alternate gene names: 54295611

Gene position: 3079772-3078750 (Counterclockwise)

Preceding gene: 54295612

Following gene: 54295610

Centisome position: 92.05

GC content: 41.06

Gene sequence:

>1023_bases
ATGCTTCATACTATTGGCATACTAATTTGGATTATTATTAAAATTATTGTGATAGTTGTCCCTTTACTGATTTCCGTGGC
CTACCTAACCTATGCGGAGCGTAAAGTGATTGGCTATATTCAAGTGCGTATCGGCCCGAACAGGGTTGGTTTAAAGGGCT
TGCTACAGCCATTTGCTGATTTATTGAAATTAATAACTAAAGAAATCATAGTTCCCACTCGATCAAACAAATACCTTTTT
GTTATTGCTCCACTTTTTGCTTTAGTCCCCTCCTTAGTCGGTTGGGCGGTAATCCCTTTTCAGGAAGGTGTTGTCCTGGC
AAATATTAACGCAGGAGTCTTATACTTATTTGCCATGAGTTCGTTGGGCGTATATGGTGTTCTTATTGCAGGATGGGCAT
CGAATTCCAAATATGCCATGTTTGGCGCACTGCGTAGTACTGCCCAAACAGTCTCTTACGAAATTGCTATGGGATTTGCT
CTTGTTGGTGTGCTCTTGGCCGCTGGAAGCATGAACTTGACTGATATTGTTAATTCTCAAAAAGGTGGAATGCTGCATTG
GTGGTTTATTCCCTTGCTCCCCCTATTCTTGGTTTTCTGGATCTCCGGTATTGCAGAAACTAACAGGGCTCCTTTTGACT
TGGCAGAAGGTGAATCAGAAATTGTTGCTGGCTTCCATGTAGAATATTCTGGCATTGGATTCGCTTTATTCTTTCTCTCT
GAATATGCCAGTATGATTTTGATTTCAACAGTTTTGGCTATTTTATTCATGGGCGGATGGCTGTCACCTTTTGAAGGTAT
TACGTTCCTGGATCAAATCTTTTTTATAGTACCCGGATTTGTTTGGTTGCTTCTGAAAATTAGTTTCTTCCTTTTTGTGT
ATTTGTGGGTAAGGGCTACTTTCCCCCGATATCGTTATGACCAGCTTATGCGTTTAGGCTGGAAGGTACTTATCCCTGTT
ACTATAGTTTGGTTAATAGTAACCGCCGTTATGGTGGTTGCTCATGTCAAGCCATGGTTTTGA

Upstream 100 bases:

>100_bases
TGCGGTTGATGTTGTGTGGGTGGCAAATGCAATGCCAGAAACAGTTGACCTTGGTCACTCGTTTGCTGCAATAACAATAA
AGCGCTAGAAAGGTATAAAA

Downstream 100 bases:

>100_bases
CGGTTAGAAGAGAAGCCGATGAAAAAAGTATATCATTATATAATTCACTATGTTCGTACCTACTTACTGTTAGAGCTATT
AGCCGGTTTATGGTTAACAG

Product: NADH-quinone oxidoreductase chain H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLHTIGILIWIIIKIIVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTAVMVVAHVKPWF

Sequences:

>Translated_340_residues
MLHTIGILIWIIIKIIVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTAVMVVAHVKPWF
>Mature_340_residues
MLHTIGILIWIIIKIIVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFADLLKLITKEIIVPTRSNKYLF
VIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMSSLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFA
LVGVLLAAGSMNLTDIVNSQKGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRATFPRYRYDQLMRLGWKVLIPV
TIVWLIVTAVMVVAHVKPWF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=320, Percent_Identity=42.5, Blast_Score=244, Evalue=7e-65,
Organism=Escherichia coli, GI1788618, Length=323, Percent_Identity=42.4148606811146, Blast_Score=280, Evalue=6e-77,
Organism=Escherichia coli, GI1789077, Length=195, Percent_Identity=29.7435897435897, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37968; Mature: 37968

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHTIGILIWIIIKIIVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LLKLITKEIIVPTRSNKYLFVIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMS
HHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCEEEEECCCCEEEEECCCHHHHHHHHH
SLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFALVGVLLAAGSMNLTDIVNSQ
HCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
KGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHH
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPRYRYDQLMRLGWKVLIPVTIVWLIVTAVMVVAHVKPWF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLHTIGILIWIIIKIIVIVVPLLISVAYLTYAERKVIGYIQVRIGPNRVGLKGLLQPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHH
LLKLITKEIIVPTRSNKYLFVIAPLFALVPSLVGWAVIPFQEGVVLANINAGVLYLFAMS
HHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCEEEEECCCCEEEEECCCHHHHHHHHH
SLGVYGVLIAGWASNSKYAMFGALRSTAQTVSYEIAMGFALVGVLLAAGSMNLTDIVNSQ
HCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
KGGMLHWWFIPLLPLFLVFWISGIAETNRAPFDLAEGESEIVAGFHVEYSGIGFALFFLS
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHH
EYASMILISTVLAILFMGGWLSPFEGITFLDQIFFIVPGFVWLLLKISFFLFVYLWVRAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPRYRYDQLMRLGWKVLIPVTIVWLIVTAVMVVAHVKPWF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA