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The map label for this gene is coaE [H]

Identifier: 54294492

GI number: 54294492

Start: 1739483

End: 1740088

Strand: Direct

Name: coaE [H]

Synonym: lpl1561

Alternate gene names: 54294492

Gene position: 1739483-1740088 (Clockwise)

Preceding gene: 54294491

Following gene: 54294493

Centisome position: 51.99

GC content: 35.64

Gene sequence:

>606_bases
ATGGTTTATTCAGTGGGACTAACTGGTAATATTGCCAGTGGCAAAAGTACAGTCGCAGAATTTTTTTCCGAGCTGGGTAT
AAATGTTATTTATGCAGATAAAATTGCCAAAGAATTAACTTCTAAAGATACACCCTGCTACCAGGATATTATTTTACATT
TTGGTTCTTCAGTGGTTCTTAATAATGGTGAGCTTGATCGGAAGCATATAAGAGATATTATATTTTCCAATTCAAATGAG
CGCTTATGGCTTGAAAGTCTATTACATCCAGTCATCCGTAAAAAAATTGAAGAGCAACTCATCGTCTGCACTTCGCCCTA
TTGCCTTATTGAAATTCCTTTGTTGTTTAATAAACATCACTACCCCTATCTTCAAAAAGTTCTATTGGTTATTGCTCCCC
TGGAATCTCAGCTAGACAGAATTGTTAAAAGAGATCATTGCACAAAAAAACAAGCATTAGCTATTTTAGCCACGCAACCT
AATTTAGAGCAGCGCCTGGAAGCAGCGGATGATGTGCTTATCAATGAATCTGGATTGAGTGAATTAAAAGCTAAGGTGAA
TAAGCTTCATCAAAAATATCTTAGGGAAGCAAAAATAAAACAGTAA

Upstream 100 bases:

>100_bases
TTAGCTGCCCAGGCCTATTGTAAAGAAAACAGTACACTACCTGCTACTTGTTATATTAATATGGTAACTTGTGCAAACAA
AAATGAAGGAGCCCACTCAG

Downstream 100 bases:

>100_bases
CAATAAATTTCTAGCAAAAGACCAGTTAATATATGGATTTTAAAGATTTTTTTATTTTCAACAACTTTTATGTTAGTCTT
AACACAAAATTCACCTTAAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKDTPCYQDIILHFGSSVVLNNGELDRKHIRDIIFSNSNE
RLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQP
NLEQRLEAADDVLINESGLSELKAKVNKLHQKYLREAKIKQ

Sequences:

>Translated_201_residues
MVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKDTPCYQDIILHFGSSVVLNNGELDRKHIRDIIFSNSNE
RLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQP
NLEQRLEAADDVLINESGLSELKAKVNKLHQKYLREAKIKQ
>Mature_201_residues
MVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKDTPCYQDIILHFGSSVVLNNGELDRKHIRDIIFSNSNE
RLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQP
NLEQRLEAADDVLINESGLSELKAKVNKLHQKYLREAKIKQ

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=198, Percent_Identity=33.8383838383838, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI191252795, Length=198, Percent_Identity=33.8383838383838, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI110227607, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI110227605, Length=204, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227603, Length=204, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227601, Length=204, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI205277394, Length=204, Percent_Identity=25.4901960784314, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786292, Length=197, Percent_Identity=42.1319796954315, Blast_Score=155, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17554944, Length=187, Percent_Identity=29.9465240641711, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25143409, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644728, Length=201, Percent_Identity=29.8507462686567, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24658602, Length=167, Percent_Identity=29.3413173652695, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22876; Mature: 22876

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKDTPCYQDIILHFGSSVVL
CEEECCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHCCCEEEE
NNGELDRKHIRDIIFSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHH
ECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHCCCC
YPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQPNLEQRLEAADDVLINESGLS
CHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHEEEEECCCCHHHHHHHHHHHEECCCCHH
ELKAKVNKLHQKYLREAKIKQ
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKDTPCYQDIILHFGSSVVL
CEEECCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHCCCEEEE
NNGELDRKHIRDIIFSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHH
ECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHCCCC
YPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQPNLEQRLEAADDVLINESGLS
CHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHEEEEECCCCHHHHHHHHHHHEECCCCHH
ELKAKVNKLHQKYLREAKIKQ
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA