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The map label for this gene is rodA [H]

Identifier: 54294260

GI number: 54294260

Start: 1481786

End: 1482904

Strand: Reverse

Name: rodA [H]

Synonym: lpl1325

Alternate gene names: 54294260

Gene position: 1482904-1481786 (Counterclockwise)

Preceding gene: 54294261

Following gene: 54294258

Centisome position: 44.32

GC content: 41.47

Gene sequence:

>1119_bases
ATGAGTAGACAAACGACTAAGCCCGTATATCGTTTTACAGCAAAGTCCCTTCACCTGGATTTTCCATTACTGGGATTAAT
ACTTACTCTTATTACCTTCGGACTCTTGATACTATACAGCGCTTCAAATGCCAATATGGGCATGATCATGCGCCAATCCA
TGAGGCTGCTCTTTGCTTTTCTAATCATGTTTGTATTGGGATTTATCCCGCCCCATAAATATAAAATCTGGACCCCATGG
ATTTATGGGGTTGGGTTAAGCCTGTTAATTGCAGTCATGCTAATGGGTAAAATTGGTAAAGGAGCTCAACGTTGGTTAGA
ACTGGGATTATTTCGTTTTCAACCTTCCGAGATTATGAAGCTGGCTGTACCTATGATGGCAGCCTGGTTTTTCGACCGAC
AATCCCATCCAAGCAGTCTACGCTCAATTGGTATTGCTTCCCTGATTATTTTTATTCCGGCTCTTCTTATTGCAAAACAA
CCTGATTTAGGTACTGCAATTATGGTTACTGTTGCCGGTTTATGTGTCGTATTTTTGGCAGGAATACGTTTTAAAATCAT
ATTATTAATTGCATTGCTGATGTGCTCAGCAATTCCTGTGGTCTGGAATTTGATGCATGACTACCAGAAACAAAGAGTCT
ATACCCTGATTGATCCTGAACAAGATCCACTTGGTGCTGGCTATCACATTATTCAATCCAAAATTGCCATTGGCTCAGGC
GGCCTAATGGGCAAAGGATGGTTAAAGGGTAGTCAATCACACCTCAACTTCTTGCCAGAACATGCTACTGATTTTATTTT
TGCGGTAAGTGGCGAAGAATTTGGCTTTGCCGGCGGATTTGCCATTGTCGCTCTAATAGTCTTAATTTCGCTACGCAGTT
TAAATATTGCCAATAATGCACAAACCACTTACACGCGCCTGCTTTCAGCCAGTCTGGCCATGACCTTTTTCCTTTCAGCA
TTTGTCAATATTGGTATGGTCATGGGGATTATTCCGGTTGTAGGTATACCTCTTCCGCTCGTCAGTTATGGTGGAACAGC
TATGGTAACTTTCCTCGCAAGCTTTGGAATTTTAATGTCGATAAGCTCGCACCGAATATTATTTAATAGCTTGAATTGA

Upstream 100 bases:

>100_bases
TTGCCATTGCCGTGGTGGTTGAAAATGATACCATCGCTTCCACTGTAGCACGTAAGGTGCTTGACACTTATTATCAACTT
TATCCTATTAAGAAAACACC

Downstream 100 bases:

>100_bases
TTTATTTTTTTATACTCTGATTTGTATAAATCACATTATGACATTTTAAAAGCTATTTCTTATGTATTTTTATTTGAACG
GTATTTTCCAAATTAATACC

Product: rod shape-determining protein rodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSRQTTKPVYRFTAKSLHLDFPLLGLILTLITFGLLILYSASNANMGMIMRQSMRLLFAFLIMFVLGFIPPHKYKIWTPW
IYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMKLAVPMMAAWFFDRQSHPSSLRSIGIASLIIFIPALLIAKQ
PDLGTAIMVTVAGLCVVFLAGIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNAQTTYTRLLSASLAMTFFLSA
FVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMSISSHRILFNSLN

Sequences:

>Translated_372_residues
MSRQTTKPVYRFTAKSLHLDFPLLGLILTLITFGLLILYSASNANMGMIMRQSMRLLFAFLIMFVLGFIPPHKYKIWTPW
IYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMKLAVPMMAAWFFDRQSHPSSLRSIGIASLIIFIPALLIAKQ
PDLGTAIMVTVAGLCVVFLAGIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNAQTTYTRLLSASLAMTFFLSA
FVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMSISSHRILFNSLN
>Mature_371_residues
SRQTTKPVYRFTAKSLHLDFPLLGLILTLITFGLLILYSASNANMGMIMRQSMRLLFAFLIMFVLGFIPPHKYKIWTPWI
YGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMKLAVPMMAAWFFDRQSHPSSLRSIGIASLIIFIPALLIAKQP
DLGTAIMVTVAGLCVVFLAGIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSGG
LMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNAQTTYTRLLSASLAMTFFLSAF
VNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMSISSHRILFNSLN

Specific function: This is one of the proteins responsible for the rod shape of E.coli. Is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=367, Percent_Identity=51.7711171662125, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1786277, Length=359, Percent_Identity=30.9192200557103, Blast_Score=161, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40856; Mature: 40725

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQTTKPVYRFTAKSLHLDFPLLGLILTLITFGLLILYSASNANMGMIMRQSMRLLFAF
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LIMFVLGFIPPHKYKIWTPWIYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMK
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LAVPMMAAWFFDRQSHPSSLRSIGIASLIIFIPALLIAKQPDLGTAIMVTVAGLCVVFLA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNA
CCCCCCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
QTTYTRLLSASLAMTFFLSAFVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
ISSHRILFNSLN
CCCCEEEEECCC
>Mature Secondary Structure 
SRQTTKPVYRFTAKSLHLDFPLLGLILTLITFGLLILYSASNANMGMIMRQSMRLLFAF
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LIMFVLGFIPPHKYKIWTPWIYGVGLSLLIAVMLMGKIGKGAQRWLELGLFRFQPSEIMK
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
LAVPMMAAWFFDRQSHPSSLRSIGIASLIIFIPALLIAKQPDLGTAIMVTVAGLCVVFLA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GIRFKIILLIALLMCSAIPVVWNLMHDYQKQRVYTLIDPEQDPLGAGYHIIQSKIAIGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
GLMGKGWLKGSQSHLNFLPEHATDFIFAVSGEEFGFAGGFAIVALIVLISLRSLNIANNA
CCCCCCCCCCCHHHHHCCHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
QTTYTRLLSASLAMTFFLSAFVNIGMVMGIIPVVGIPLPLVSYGGTAMVTFLASFGILMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
ISSHRILFNSLN
CCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]