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The map label for this gene is lidL [H]

Identifier: 54294116

GI number: 54294116

Start: 1317139

End: 1318611

Strand: Direct

Name: lidL [H]

Synonym: lpl1180

Alternate gene names: 54294116

Gene position: 1317139-1318611 (Clockwise)

Preceding gene: 54294115

Following gene: 54294117

Centisome position: 39.37

GC content: 39.04

Gene sequence:

>1473_bases
ATGATGAGACAATTGGTTGTTGCAGGATTTTTCTTATTACTTCTAACTTCCCCTTTATCAGCGCTGGATGTTGATACCTA
TCGTAGCTCACAAAAACAATTCAATACTGAGGATAAGGCGGAACAGGGTGATGCTCAAGCACAGTTTGAATTAGGGCTTC
AATATGAAAAGGGCGATGGAGTAAAAAAAGATTTAAAGAAAGCGATTTATTGGTATCAGAAAGCTGCAGATCAAGGACAA
GCTGAGGCACAAAATAATCTCGGTGTATTGTATCTTAAAGGAGAGGGGGTGTCCCAAAACAGTCAGCAAGCAATGCATTG
GTTTAAGAAGGCTTCGGAACAGGGTTTGGCTATTGGTCAAAATAATATAGGAATTCTATATGAAAATGGCCTGGGTGTTA
AAAAAGATCTGGGCCAGGCTTTTATCTGGTATCAAAAGGCTGCAGAAGGCGGAAATTCAGACGGACAATATAACCTTGCG
GTGATGTACATGTATGGCAATGGTATACCAAAAGATATCAAGAAGGCGATTCACTGGTATATCAAAGCAGCAGAGCAAGG
AGATCTTGATGCTCAAAATAATCTTGGTGTTCTTTATGAGCGAGGCGAAGAGGTTCCAAGAGATTTAAAAGCAGCTATTA
GCTGGTATACCAGAGCAGCAAATGAAGGTTCACTGATTGCTCAAACTAACCTTGGTGTATTGTATATGACTGGTGATCCT
TCCATTCAAGATGGCAAGAAAGCAATATATTGGTATGAAAAAGCAGCGGCACAAGGTGGGGAAAAAGCTCAAAATAATCT
TGGGTATATTTATGAACAAGGAGTTGGTACAGAAAAGGATATGAAAAAGGCTATTTACTGGTACGAAAAAGCCGCAGAGA
ATGGATTTACTCTGGCTCAAAATAATTTAGGTGTTCTCTATTCAAATGATGGCGAGCTGCAAGATTACAAAAAGGCTTAT
TTATGGTTCAAAAAAGCCGCAGATCAAGGATTTGCCGAAGCCCAAAATAACTTGGGTTTAATGTATATGAAAGGCAATGG
ATTGTCAGTTAATTATCACGAAGCAGTCTTGTGGTACAAGAGAGCGGCAGAACAAGGATTACCTTTAGCGCAACATAATC
TGGCGATTATGTATATGAAAGGCTTGGGGATAAAGAAAGACAATAAACTGGCCATTAAGTGGTACCAAAAAGCTGCTGAA
AAAGGATTGGATTTGGCGCAAAACAATTTGGCGGTTATGTATATACGTGGTGAAGGAGTAAAAATAGATTTTAAGAAGGC
TATGTATTGGTATCAAAAGGCAGCTGAACAAGGTTTGGATTTGGCACAAATTAATCTGGGTATTATGTATCTTGATGGCA
TGGGTGTTGATAAAGATTTCGCTAAAGCGAAGTATTGGATTGGAAAAGCTAAGGACAGCGGTTCTCAAGATGCGCTGACC
ATATGGAATAAAAATAAATTGTGGAAATATTAG

Upstream 100 bases:

>100_bases
ATCTTACTCCTAATAGATGCACTTTGCTTGTCTGGCGCCAGAGCATCAATGTTTGTTCATCATCAATTGTGCTATAATTG
AACAATGATTACAGGGAGGT

Downstream 100 bases:

>100_bases
GGATCATTGGTGTGGGTCTTAGTTGATGTATTGTGCAAAATGCTCAAGTCTGGTTATATAATTATAATACGCTGAATAAT
CTAATGGATTAGAAAAGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MMRQLVVAGFFLLLLTSPLSALDVDTYRSSQKQFNTEDKAEQGDAQAQFELGLQYEKGDGVKKDLKKAIYWYQKAADQGQ
AEAQNNLGVLYLKGEGVSQNSQQAMHWFKKASEQGLAIGQNNIGILYENGLGVKKDLGQAFIWYQKAAEGGNSDGQYNLA
VMYMYGNGIPKDIKKAIHWYIKAAEQGDLDAQNNLGVLYERGEEVPRDLKAAISWYTRAANEGSLIAQTNLGVLYMTGDP
SIQDGKKAIYWYEKAAAQGGEKAQNNLGYIYEQGVGTEKDMKKAIYWYEKAAENGFTLAQNNLGVLYSNDGELQDYKKAY
LWFKKAADQGFAEAQNNLGLMYMKGNGLSVNYHEAVLWYKRAAEQGLPLAQHNLAIMYMKGLGIKKDNKLAIKWYQKAAE
KGLDLAQNNLAVMYIRGEGVKIDFKKAMYWYQKAAEQGLDLAQINLGIMYLDGMGVDKDFAKAKYWIGKAKDSGSQDALT
IWNKNKLWKY

Sequences:

>Translated_490_residues
MMRQLVVAGFFLLLLTSPLSALDVDTYRSSQKQFNTEDKAEQGDAQAQFELGLQYEKGDGVKKDLKKAIYWYQKAADQGQ
AEAQNNLGVLYLKGEGVSQNSQQAMHWFKKASEQGLAIGQNNIGILYENGLGVKKDLGQAFIWYQKAAEGGNSDGQYNLA
VMYMYGNGIPKDIKKAIHWYIKAAEQGDLDAQNNLGVLYERGEEVPRDLKAAISWYTRAANEGSLIAQTNLGVLYMTGDP
SIQDGKKAIYWYEKAAAQGGEKAQNNLGYIYEQGVGTEKDMKKAIYWYEKAAENGFTLAQNNLGVLYSNDGELQDYKKAY
LWFKKAADQGFAEAQNNLGLMYMKGNGLSVNYHEAVLWYKRAAEQGLPLAQHNLAIMYMKGLGIKKDNKLAIKWYQKAAE
KGLDLAQNNLAVMYIRGEGVKIDFKKAMYWYQKAAEQGLDLAQINLGIMYLDGMGVDKDFAKAKYWIGKAKDSGSQDALT
IWNKNKLWKY
>Mature_490_residues
MMRQLVVAGFFLLLLTSPLSALDVDTYRSSQKQFNTEDKAEQGDAQAQFELGLQYEKGDGVKKDLKKAIYWYQKAADQGQ
AEAQNNLGVLYLKGEGVSQNSQQAMHWFKKASEQGLAIGQNNIGILYENGLGVKKDLGQAFIWYQKAAEGGNSDGQYNLA
VMYMYGNGIPKDIKKAIHWYIKAAEQGDLDAQNNLGVLYERGEEVPRDLKAAISWYTRAANEGSLIAQTNLGVLYMTGDP
SIQDGKKAIYWYEKAAAQGGEKAQNNLGYIYEQGVGTEKDMKKAIYWYEKAAENGFTLAQNNLGVLYSNDGELQDYKKAY
LWFKKAADQGFAEAQNNLGLMYMKGNGLSVNYHEAVLWYKRAAEQGLPLAQHNLAIMYMKGLGIKKDNKLAIKWYQKAAE
KGLDLAQNNLAVMYIRGEGVKIDFKKAMYWYQKAAEQGLDLAQINLGIMYLDGMGVDKDFAKAKYWIGKAKDSGSQDALT
IWNKNKLWKY

Specific function: Unknown

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ybeT [H]

Homologues:

Organism=Homo sapiens, GI19923669, Length=362, Percent_Identity=33.1491712707182, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI151301150, Length=410, Percent_Identity=28.5365853658537, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI217330658, Length=177, Percent_Identity=34.4632768361582, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI217330656, Length=177, Percent_Identity=34.4632768361582, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI154689719, Length=244, Percent_Identity=30.7377049180328, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI33620759, Length=180, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI87081769, Length=321, Percent_Identity=37.6947040498442, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1786867, Length=99, Percent_Identity=42.4242424242424, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17563256, Length=411, Percent_Identity=28.2238442822384, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319410, Length=290, Percent_Identity=31.0344827586207, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319998, Length=280, Percent_Identity=31.7857142857143, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355295, Length=345, Percent_Identity=34.2028985507246, Blast_Score=155, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: NA

Molecular weight: Translated: 54961; Mature: 54961

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRQLVVAGFFLLLLTSPLSALDVDTYRSSQKQFNTEDKAEQGDAQAQFELGLQYEKGDG
CCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCCCHHHHCCCCCEEEEEEEEEECCCC
VKKDLKKAIYWYQKAADQGQAEAQNNLGVLYLKGEGVSQNSQQAMHWFKKASEQGLAIGQ
HHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEECC
NNIGILYENGLGVKKDLGQAFIWYQKAAEGGNSDGQYNLAVMYMYGNGIPKDIKKAIHWY
CCEEEEEECCCCCHHHHHHHHEEEHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHH
IKAAEQGDLDAQNNLGVLYERGEEVPRDLKAAISWYTRAANEGSLIAQTNLGVLYMTGDP
HEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCC
SIQDGKKAIYWYEKAAAQGGEKAQNNLGYIYEQGVGTEKDMKKAIYWYEKAAENGFTLAQ
CCCCCCEEEEEEEHHHHCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEE
NNLGVLYSNDGELQDYKKAYLWFKKAADQGFAEAQNNLGLMYMKGNGLSVNYHEAVLWYK
CCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCEEEHHHHHHHHH
RAAEQGLPLAQHNLAIMYMKGLGIKKDNKLAIKWYQKAAEKGLDLAQNNLAVMYIRGEGV
HHHHCCCCCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHCCCCCCCCCEEEEEEECCCE
KIDFKKAMYWYQKAAEQGLDLAQINLGIMYLDGMGVDKDFAKAKYWIGKAKDSGSQDALT
EEEHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCHHHHHHHHEEECCCCCCCCCEEE
IWNKNKLWKY
EECCCCCCCC
>Mature Secondary Structure
MMRQLVVAGFFLLLLTSPLSALDVDTYRSSQKQFNTEDKAEQGDAQAQFELGLQYEKGDG
CCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCCCHHHHCCCCCEEEEEEEEEECCCC
VKKDLKKAIYWYQKAADQGQAEAQNNLGVLYLKGEGVSQNSQQAMHWFKKASEQGLAIGQ
HHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEECC
NNIGILYENGLGVKKDLGQAFIWYQKAAEGGNSDGQYNLAVMYMYGNGIPKDIKKAIHWY
CCEEEEEECCCCCHHHHHHHHEEEHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHH
IKAAEQGDLDAQNNLGVLYERGEEVPRDLKAAISWYTRAANEGSLIAQTNLGVLYMTGDP
HEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCC
SIQDGKKAIYWYEKAAAQGGEKAQNNLGYIYEQGVGTEKDMKKAIYWYEKAAENGFTLAQ
CCCCCCEEEEEEEHHHHCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEE
NNLGVLYSNDGELQDYKKAYLWFKKAADQGFAEAQNNLGLMYMKGNGLSVNYHEAVLWYK
CCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCEEEHHHHHHHHH
RAAEQGLPLAQHNLAIMYMKGLGIKKDNKLAIKWYQKAAEKGLDLAQNNLAVMYIRGEGV
HHHHCCCCCCCCCEEEEEEECCCCCCCCCEEHHHHHHHHHCCCCCCCCCEEEEEEECCCE
KIDFKKAMYWYQKAAEQGLDLAQINLGIMYLDGMGVDKDFAKAKYWIGKAKDSGSQDALT
EEEHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCHHHHHHHHEEECCCCCCCCCEEE
IWNKNKLWKY
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]