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The map label for this gene is argE [H]

Identifier: 54294108

GI number: 54294108

Start: 1306415

End: 1307569

Strand: Direct

Name: argE [H]

Synonym: lpl1172

Alternate gene names: 54294108

Gene position: 1306415-1307569 (Clockwise)

Preceding gene: 54294107

Following gene: 54294109

Centisome position: 39.05

GC content: 38.79

Gene sequence:

>1155_bases
ATGACAACTTTAGATTGGTTAAAACAACTCATTTCTTTTGATACTACTTCGCGGAACTCTAATTTATCATTGATTGAATA
TTTGGCGAATGGGTTAAATGATTTCAAGGTAGATCCTATCCTAATTCACGATAGTAAAGAGCAGAAAGCTAATCTGTTAG
CTACTTTGCCAGGAAAACAAGGGGGGGTGGAAGGGGGTATTATTCTGTCTGGCCATACTGATGTTGTTCCTGTTGACGGT
CAAATTTGGGATAGTGATCCTTTTCAAGCCACTCTTAAAAATAACAAAGTGTATGGTCGTGGCGCGTGTGACATGAAAGG
ATTTATTGCAGTCGTGATGGCTTTAGTCCCACAATTGAAAGAAATGAACCTGGATTTTCCAGTTCATTTTGCATTTTCTT
ATGATGAGGAAATTGGTTGTCTTGGTGTGCCTTCTCTGATCGATAAAATAGTGGAGCTTAATTATCAACCGCGTGCTTGC
ATTGTAGGTGAGCCAACCTTAATGAAGCCTGTTGTGGGTCATAAAGGCAAATATTCTTATCGCTGCCAAATACATGGTGT
AGCTGCCCACTCTTCATTAACGAATCAAGGATGTAATGCTATCGAACATGCCGCGTCTTTTATAAGCTATCTTCGAGGGA
TGGCTAATGAATTTAAAAAATATGGAAATCGAGATTTTTCTTATGATGTTCCATATACAACACTTACCACCAATCTGATC
AAAGGAGGTAATGCTTATAATACTATTCCAAACTTGTGTGAGTTTGTTTTTGAATTTAGAAATCTGTCTACTGACAGCTC
TGAGGATTTAAATCAGGAAATTATGTCTTATGTTAAGGAAGAGCTTGCCCCTAACCTGCATCAGGATCATCCTGACTCTA
ATGTTAATCTTGATACGATAGCAAAAGCTCCTGGTTTGGATATGCCGATTACAGATCCTTTTGTCAGAGCAGCTCAAACA
GTTTGCCAGAGCGATAAGCTGATGAAAGTAGCTTACGCTACAGAAGCCGGGCTATTTCAACAGGCAGAAATTCCTACTAT
TGTGTGTGGTCCAGGTAGTATCGAACAAGCCCATAGAGCAAATGAATATGTTGAAGTAGAGCAATTACGATTATGTGAGG
AATTTATAATCAATATGCTGCGCTCTCATTTTTGA

Upstream 100 bases:

>100_bases
CGGTCTTTATCAGTTTGCTAGCAGTCCTTGCTTATCAGGAGGAAAGGAAGCTATCTGAGAATCAGCCAGAACATCTCGTT
GCAATTTAAAAGGTAGGAAT

Downstream 100 bases:

>100_bases
GCTTTATCAGATTGGTAAGTAAAAAATCATCGGTATTTGATGCTGATTTTACTAGCACTTTTATAAGGTATTCACAAAGA
TATACACAGTTTTTGTGGAT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKVDPILIHDSKEQKANLLATLPGKQGGVEGGIILSGHTDVVPVDG
QIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRAC
IVGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQEIMSYVKEELAPNLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQT
VCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF

Sequences:

>Translated_384_residues
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKVDPILIHDSKEQKANLLATLPGKQGGVEGGIILSGHTDVVPVDG
QIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRAC
IVGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQEIMSYVKEELAPNLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQT
VCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF
>Mature_383_residues
TTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKVDPILIHDSKEQKANLLATLPGKQGGVEGGIILSGHTDVVPVDGQ
IWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACI
VGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLIK
GGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQEIMSYVKEELAPNLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQTV
CQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=369, Percent_Identity=32.520325203252, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788816, Length=227, Percent_Identity=28.6343612334802, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42623; Mature: 42492

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKVDPILIHDSKEQKANLLATLPGKQ
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHCCEEEECCCCC
GGVEGGIILSGHTDVVPVDGQIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLK
CCCCCCEEEECCCCEEECCCEECCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
EMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACIVGEPTLMKPVVGHKGKYSY
HCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEE
RCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
EEEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQEIMSYVKEELAPNLHQDHPDSNVNLDTI
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
AKAPGLDMPITDPFVRAAQTVCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEECCCCHHHHHHH
NEYVEVEQLRLCEEFIINMLRSHF
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKVDPILIHDSKEQKANLLATLPGKQ
CHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHCCEEEECCCCC
GGVEGGIILSGHTDVVPVDGQIWDSDPFQATLKNNKVYGRGACDMKGFIAVVMALVPQLK
CCCCCCEEEECCCCEEECCCEECCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
EMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACIVGEPTLMKPVVGHKGKYSY
HCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEE
RCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
EEEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQEIMSYVKEELAPNLHQDHPDSNVNLDTI
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
AKAPGLDMPITDPFVRAAQTVCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEECCCCHHHHHHH
NEYVEVEQLRLCEEFIINMLRSHF
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]