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The map label for this gene is rocC [H]

Identifier: 54293942

GI number: 54293942

Start: 1131583

End: 1133046

Strand: Reverse

Name: rocC [H]

Synonym: lpl0999

Alternate gene names: 54293942

Gene position: 1133046-1131583 (Counterclockwise)

Preceding gene: 54293950

Following gene: 54293940

Centisome position: 33.87

GC content: 40.71

Gene sequence:

>1464_bases
GTGAAGACTAATATTCCAACCCTATCAAAACCCATTAAAGACAGTGGTTACAGACGAGGTTTAAAAGATCGTCATGTCCA
ACTGATTGCACTAGGTGGAATTATCGGCTCTGGATATTTTTTAGGAACCGGTGAAGTAATTAATCTTGTTGGCCCCTCTG
TGTTTATTGCCTATTTACTTGGTGGGTTAATTATTTACCTAACCATGTTATGTATGGGTGAATTAGCAGTCGCCATTCCA
ATTTCCGGCTCTTTTGTTACTTACACTTCTGATTTTATATCCCCAACTGTCGCCTGCGGTGTCGGGTGGTCATATTGGAT
TACCTGGGTCGCCTATATCCCCGCAGAATGTGTTGCGGGAGGGATCATAATGGAATTGTTTACTGGGGTGAGCGGTTACA
TATGGGTGGTTTGCTTCGGATTAGTTATTACCTATATTAACCTTGCTAAAGTCGATACGTTTGGTGAAATTGAATTCTGG
CTCGCCTTAATTAAAATTATCTCATTACTCGCCTTTGTTTTCCTGGCAATACTAATTTTCTTTGGACTCATTCATGGATC
AGAACCACCCGGTATAATAGGATTTAAGTACCTGTTAGACGATGGAGGTCTGTTACCTAATGGGGCAATGTCGTTGTTGA
CAGCCATGGTTCTTTTGCTGGTTAATTATCAAGGATCTGAAATCATAGGACTTGCAGCAGGAGAATCTGAAAACCCTGCC
CGAATGATCCCTCACGCCATCCGTAACGTTACTTTCAGAATCCTGTTTCTCTACATCATTCCAGTATTTTGTCTGGTTTT
AATTTTTCCCTGGCAAAAAGCTGGGTTATCCAACTCAGTCTTCGCTGATGCGCTTAATTTCTACGGCCTGAAATGGGCAG
GAGCAGTAACGAGTTTTGTTACTCTGTCTGCAACCTTATCCTGCGCTAATTCCGGATTTTACGGTGCTGTGCGTTCTTTA
AATGCTTTGGCGCGTGATGGTATGGCTCCACACGTTTTAGCCAAATTTAATCAAAACTCTGTTCCTCAGAACGCCGTTAT
TGCCACACTGATTGGAGTTTGGATTCTTTTAGGCGTGGGTTACTTTTTTGGTCAAACGAAACTCTATATCGCTTTATTAT
TAGTATCCGGTTTTACCGGAACGCTGGCTTGGCTTTCTTTATGCATTGCTCAAATCAGCTTTAGAAACCGTTTGTATAAA
GCCGGTTACTCCATTAAAGATCTCCGTTATGTAACACCTTATTCACCCTATACCGGAATTCTTGCTGTCATTTTGATGGT
TGGCTCCTTATTTTTCTTACTGCTAAATAAAGATCCTATCTATAAATTATCATTTATTATTGGTGTGGTGAGTTTCATTA
TACCCGTCATCATCTATAAGGTCTTTGATTTATCCAAGGTTAGGAAAAAAGCATTGCATGTAAAAAGCCGGGTCAAATTC
CAGGATTTATTTCCGCCACAGTAA

Upstream 100 bases:

>100_bases
ATGAAAAATATTTTTTAATCTGGAGCAGTTTTAAATTTATATGGATAAATATAACATTAGCTCTATTATTTTTTACTAAC
ATAGTGAGAAAAAACAGCCC

Downstream 100 bases:

>100_bases
ATTGAACATTACTTTTTGAAGTATTCTCGGGCGTGTCAAAACTCATTTATCACGCCCCGATTCATAAAATCACAGCAACC
AGCAAGCATCAATCAAAAAA

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MKTNIPTLSKPIKDSGYRRGLKDRHVQLIALGGIIGSGYFLGTGEVINLVGPSVFIAYLLGGLIIYLTMLCMGELAVAIP
ISGSFVTYTSDFISPTVACGVGWSYWITWVAYIPAECVAGGIIMELFTGVSGYIWVVCFGLVITYINLAKVDTFGEIEFW
LALIKIISLLAFVFLAILIFFGLIHGSEPPGIIGFKYLLDDGGLLPNGAMSLLTAMVLLLVNYQGSEIIGLAAGESENPA
RMIPHAIRNVTFRILFLYIIPVFCLVLIFPWQKAGLSNSVFADALNFYGLKWAGAVTSFVTLSATLSCANSGFYGAVRSL
NALARDGMAPHVLAKFNQNSVPQNAVIATLIGVWILLGVGYFFGQTKLYIALLLVSGFTGTLAWLSLCIAQISFRNRLYK
AGYSIKDLRYVTPYSPYTGILAVILMVGSLFFLLLNKDPIYKLSFIIGVVSFIIPVIIYKVFDLSKVRKKALHVKSRVKF
QDLFPPQ

Sequences:

>Translated_487_residues
MKTNIPTLSKPIKDSGYRRGLKDRHVQLIALGGIIGSGYFLGTGEVINLVGPSVFIAYLLGGLIIYLTMLCMGELAVAIP
ISGSFVTYTSDFISPTVACGVGWSYWITWVAYIPAECVAGGIIMELFTGVSGYIWVVCFGLVITYINLAKVDTFGEIEFW
LALIKIISLLAFVFLAILIFFGLIHGSEPPGIIGFKYLLDDGGLLPNGAMSLLTAMVLLLVNYQGSEIIGLAAGESENPA
RMIPHAIRNVTFRILFLYIIPVFCLVLIFPWQKAGLSNSVFADALNFYGLKWAGAVTSFVTLSATLSCANSGFYGAVRSL
NALARDGMAPHVLAKFNQNSVPQNAVIATLIGVWILLGVGYFFGQTKLYIALLLVSGFTGTLAWLSLCIAQISFRNRLYK
AGYSIKDLRYVTPYSPYTGILAVILMVGSLFFLLLNKDPIYKLSFIIGVVSFIIPVIIYKVFDLSKVRKKALHVKSRVKF
QDLFPPQ
>Mature_487_residues
MKTNIPTLSKPIKDSGYRRGLKDRHVQLIALGGIIGSGYFLGTGEVINLVGPSVFIAYLLGGLIIYLTMLCMGELAVAIP
ISGSFVTYTSDFISPTVACGVGWSYWITWVAYIPAECVAGGIIMELFTGVSGYIWVVCFGLVITYINLAKVDTFGEIEFW
LALIKIISLLAFVFLAILIFFGLIHGSEPPGIIGFKYLLDDGGLLPNGAMSLLTAMVLLLVNYQGSEIIGLAAGESENPA
RMIPHAIRNVTFRILFLYIIPVFCLVLIFPWQKAGLSNSVFADALNFYGLKWAGAVTSFVTLSATLSCANSGFYGAVRSL
NALARDGMAPHVLAKFNQNSVPQNAVIATLIGVWILLGVGYFFGQTKLYIALLLVSGFTGTLAWLSLCIAQISFRNRLYK
AGYSIKDLRYVTPYSPYTGILAVILMVGSLFFLLLNKDPIYKLSFIIGVVSFIIPVIIYKVFDLSKVRKKALHVKSRVKF
QDLFPPQ

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=363, Percent_Identity=25.068870523416, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788480, Length=431, Percent_Identity=36.6589327146172, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI87081708, Length=473, Percent_Identity=31.7124735729387, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI48994972, Length=473, Percent_Identity=32.76955602537, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789017, Length=408, Percent_Identity=33.8235294117647, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1786789, Length=473, Percent_Identity=31.2896405919662, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1786602, Length=456, Percent_Identity=30.2631578947368, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1786302, Length=386, Percent_Identity=31.8652849740933, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1790653, Length=368, Percent_Identity=31.7934782608696, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87081915, Length=415, Percent_Identity=30.6024096385542, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI87081869, Length=319, Percent_Identity=24.1379310344828, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=366, Percent_Identity=24.3169398907104, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324061, Length=467, Percent_Identity=30.1927194860814, Blast_Score=193, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6320772, Length=435, Percent_Identity=29.6551724137931, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324059, Length=430, Percent_Identity=31.8604651162791, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6324990, Length=441, Percent_Identity=28.5714285714286, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6324924, Length=448, Percent_Identity=27.2321428571429, Blast_Score=169, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6322892, Length=456, Percent_Identity=30.4824561403509, Blast_Score=169, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324553, Length=440, Percent_Identity=28.4090909090909, Blast_Score=168, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321053, Length=434, Percent_Identity=30.4147465437788, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320717, Length=438, Percent_Identity=26.9406392694064, Blast_Score=156, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6321629, Length=479, Percent_Identity=27.348643006263, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6319824, Length=434, Percent_Identity=27.4193548387097, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6319543, Length=430, Percent_Identity=27.4418604651163, Blast_Score=146, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=458, Percent_Identity=24.235807860262, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322967, Length=432, Percent_Identity=27.7777777777778, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=416, Percent_Identity=25, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6319608, Length=438, Percent_Identity=25.3424657534247, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324981, Length=447, Percent_Identity=26.3982102908277, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320364, Length=559, Percent_Identity=24.3291592128801, Blast_Score=104, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53203; Mature: 53203

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNIPTLSKPIKDSGYRRGLKDRHVQLIALGGIIGSGYFLGTGEVINLVGPSVFIAYLL
CCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCHHCCEEECCCHHHHHHHHHHHHHHHH
GGLIIYLTMLCMGELAVAIPISGSFVTYTSDFISPTVACGVGWSYWITWVAYIPAECVAG
HHHHHHHHHHHHHHHEEEEECCCCEEEEEHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHH
GIIMELFTGVSGYIWVVCFGLVITYINLAKVDTFGEIEFWLALIKIISLLAFVFLAILIF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FGLIHGSEPPGIIGFKYLLDDGGLLPNGAMSLLTAMVLLLVNYQGSEIIGLAAGESENPA
HHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
RMIPHAIRNVTFRILFLYIIPVFCLVLIFPWQKAGLSNSVFADALNFYGLKWAGAVTSFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
TLSATLSCANSGFYGAVRSLNALARDGMAPHVLAKFNQNSVPQNAVIATLIGVWILLGVG
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YFFGQTKLYIALLLVSGFTGTLAWLSLCIAQISFRNRLYKAGYSIKDLRYVTPYSPYTGI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHH
LAVILMVGSLFFLLLNKDPIYKLSFIIGVVSFIIPVIIYKVFDLSKVRKKALHVKSRVKF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDLFPPQ
CCCCCCC
>Mature Secondary Structure
MKTNIPTLSKPIKDSGYRRGLKDRHVQLIALGGIIGSGYFLGTGEVINLVGPSVFIAYLL
CCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCHHCCEEECCCHHHHHHHHHHHHHHHH
GGLIIYLTMLCMGELAVAIPISGSFVTYTSDFISPTVACGVGWSYWITWVAYIPAECVAG
HHHHHHHHHHHHHHHEEEEECCCCEEEEEHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHH
GIIMELFTGVSGYIWVVCFGLVITYINLAKVDTFGEIEFWLALIKIISLLAFVFLAILIF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FGLIHGSEPPGIIGFKYLLDDGGLLPNGAMSLLTAMVLLLVNYQGSEIIGLAAGESENPA
HHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCH
RMIPHAIRNVTFRILFLYIIPVFCLVLIFPWQKAGLSNSVFADALNFYGLKWAGAVTSFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHCCCHHHHHHHHHH
TLSATLSCANSGFYGAVRSLNALARDGMAPHVLAKFNQNSVPQNAVIATLIGVWILLGVG
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YFFGQTKLYIALLLVSGFTGTLAWLSLCIAQISFRNRLYKAGYSIKDLRYVTPYSPYTGI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHH
LAVILMVGSLFFLLLNKDPIYKLSFIIGVVSFIIPVIIYKVFDLSKVRKKALHVKSRVKF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDLFPPQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-lysine [Periplasm] = Proton [Cytoplasm] + L-lysine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]