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The map label for this gene is nadA [H]

Identifier: 54293776

GI number: 54293776

Start: 942494

End: 943837

Strand: Reverse

Name: nadA [H]

Synonym: lpl0832

Alternate gene names: 54293776

Gene position: 943837-942494 (Counterclockwise)

Preceding gene: 54293777

Following gene: 54293772

Centisome position: 28.21

GC content: 39.96

Gene sequence:

>1344_bases
ATGTTTAAAAATTCAACTACTTACCAACCCGAAGCGACCCTCATGGCTATTCGTAATGATATGGCTATATGTCAAAGCGA
TTATCCATTGGATTGGTATCAAGAAGATTTTATTCCTTATGCTCAGGAATATCAGGCTTTACCCGATAGAAAGCTTACGA
CTGTTTTAAATTGGATGAAACCTTATCTTACTAAAGCCCAAAATCATTTTGGTAACAAACTGTTACTTCTTGCCCATTAT
TATATGGGTGGAGAAATTGTTCGATTAATTGAACAGTTTGGGGGTAAAATCGGTGACTCCTACCAATTGGCTTTGATGGC
TGCGAATAACCCTGAAAAATCAGTCATAGTGGAATCAGCAGTTCATTTTATGGCGGAATCCATAAGCATTTTGGCTAATG
AAAATCAACACGTCTACATCACCAATCCCAAGTCAGGCTGCACCATGGAAATGCTTGCCAAAGACTTTATGGTCGAGCCT
GCTTTCCTTGATTTAAATGAGCGTTATGGTGCTGAAAATATTTTACCTGTTTGCTACATGAATACTTCTGGTCGTGTGAA
AGCCATGACCGGTGCCCAGGGAGGAGCGGTTTGTACAAGCTCCAATGTCAAAAAAATTTTTCAATGGGCTCAAAAGCAAA
ATAAAAAAATCCTGTTTATTCCTGATCAACACATGGGAGAAAATGTCGCTTACTGGTTGGGAATTAAAAATCTCGCTTAT
TGGCCTGGAGGAACTGCCGGCGCTAATTATTCACTACCAGAGCAAGACAAAAAAACACTCAAGCAATTTGACAAAGCAGA
GTTGATTTTATTCGCAAGCCAATGCGCGGTTCATACCCATTATCAACCTGAAATGTGTGATTATTGGAAAAGCCAGGGAT
ACACTACCATTGTACATCCAGAATGTCGTAATGATGTCATCAAAGTGGCTGATTACTCAGGTTCTACTGCATTCATATGG
GATCTGGTAGTCCATGACAAGGCAGGTACAAAAAGTTATGCCATCGGAACTGAAAACCACATGGTAGAAAACTTAAAGCA
ATATTGTAAAAACCTTGGAATTCGTGTTGTAAATCTTGCTGAAGCCCCTCAAAAAGACACTGAAAAAGGAGTCGGATGTG
GTTGTGCTACCATGTCTCGCAATGACCCGCCACATCTGGTCGCTCTCCTCGATTTACTTCGCCAGGGCAAATCTATGCCT
TATAATGAAGTAAAAGCAGGTGATGTGGTCAATGAATTCACAGGAACCAGAAATAGACTGCCAGTCAACGATCAACAATG
GGTTATAAATAATGCCAAAAAAGCTTTGGAAATGATGATTAATATCACAGAAGACAGGGTTTAA

Upstream 100 bases:

>100_bases
ACAGGCAGACAGTTCATTAGGATAGCTTGGTAAAAGCTATCCCATTAACAATAATGAAAGAACCCTTCCCACAAATCCCT
AATGACTAGAGGTAGATTTA

Downstream 100 bases:

>100_bases
TAAAGGATTATCAAAAAGCTATTATTGCATATACCCGCTCCCTAACGGTCGCGGCTCAGTTTTCCATCAAATCCGAGCCG
CGACCGTTAGGGAGCGGATG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MFKNSTTYQPEATLMAIRNDMAICQSDYPLDWYQEDFIPYAQEYQALPDRKLTTVLNWMKPYLTKAQNHFGNKLLLLAHY
YMGGEIVRLIEQFGGKIGDSYQLALMAANNPEKSVIVESAVHFMAESISILANENQHVYITNPKSGCTMEMLAKDFMVEP
AFLDLNERYGAENILPVCYMNTSGRVKAMTGAQGGAVCTSSNVKKIFQWAQKQNKKILFIPDQHMGENVAYWLGIKNLAY
WPGGTAGANYSLPEQDKKTLKQFDKAELILFASQCAVHTHYQPEMCDYWKSQGYTTIVHPECRNDVIKVADYSGSTAFIW
DLVVHDKAGTKSYAIGTENHMVENLKQYCKNLGIRVVNLAEAPQKDTEKGVGCGCATMSRNDPPHLVALLDLLRQGKSMP
YNEVKAGDVVNEFTGTRNRLPVNDQQWVINNAKKALEMMINITEDRV

Sequences:

>Translated_447_residues
MFKNSTTYQPEATLMAIRNDMAICQSDYPLDWYQEDFIPYAQEYQALPDRKLTTVLNWMKPYLTKAQNHFGNKLLLLAHY
YMGGEIVRLIEQFGGKIGDSYQLALMAANNPEKSVIVESAVHFMAESISILANENQHVYITNPKSGCTMEMLAKDFMVEP
AFLDLNERYGAENILPVCYMNTSGRVKAMTGAQGGAVCTSSNVKKIFQWAQKQNKKILFIPDQHMGENVAYWLGIKNLAY
WPGGTAGANYSLPEQDKKTLKQFDKAELILFASQCAVHTHYQPEMCDYWKSQGYTTIVHPECRNDVIKVADYSGSTAFIW
DLVVHDKAGTKSYAIGTENHMVENLKQYCKNLGIRVVNLAEAPQKDTEKGVGCGCATMSRNDPPHLVALLDLLRQGKSMP
YNEVKAGDVVNEFTGTRNRLPVNDQQWVINNAKKALEMMINITEDRV
>Mature_447_residues
MFKNSTTYQPEATLMAIRNDMAICQSDYPLDWYQEDFIPYAQEYQALPDRKLTTVLNWMKPYLTKAQNHFGNKLLLLAHY
YMGGEIVRLIEQFGGKIGDSYQLALMAANNPEKSVIVESAVHFMAESISILANENQHVYITNPKSGCTMEMLAKDFMVEP
AFLDLNERYGAENILPVCYMNTSGRVKAMTGAQGGAVCTSSNVKKIFQWAQKQNKKILFIPDQHMGENVAYWLGIKNLAY
WPGGTAGANYSLPEQDKKTLKQFDKAELILFASQCAVHTHYQPEMCDYWKSQGYTTIVHPECRNDVIKVADYSGSTAFIW
DLVVHDKAGTKSYAIGTENHMVENLKQYCKNLGIRVVNLAEAPQKDTEKGVGCGCATMSRNDPPHLVALLDLLRQGKSMP
YNEVKAGDVVNEFTGTRNRLPVNDQQWVINNAKKALEMMINITEDRV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=247, Percent_Identity=25.5060728744939, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 50410; Mature: 50410

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNSTTYQPEATLMAIRNDMAICQSDYPLDWYQEDFIPYAQEYQALPDRKLTTVLNWMK
CCCCCCCCCCCCEEEEHHCCHHHHCCCCCCCHHHHHCCCHHHHHHCCCCHHHHHHHHHHH
PYLTKAQNHFGNKLLLLAHYYMGGEIVRLIEQFGGKIGDSYQLALMAANNPEKSVIVESA
HHHHHHHHHCCCEEEEEEHHHHCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHH
VHFMAESISILANENQHVYITNPKSGCTMEMLAKDFMVEPAFLDLNERYGAENILPVCYM
HHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCHHHCCCCCCCEEEEE
NTSGRVKAMTGAQGGAVCTSSNVKKIFQWAQKQNKKILFIPDQHMGENVAYWLGIKNLAY
CCCCCEEEEECCCCCEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCEEE
WPGGTAGANYSLPEQDKKTLKQFDKAELILFASQCAVHTHYQPEMCDYWKSQGYTTIVHP
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECHHHEECCCCCHHHHHHHHCCCEEEECC
ECRNDVIKVADYSGSTAFIWDLVVHDKAGTKSYAIGTENHMVENLKQYCKNLGIRVVNLA
HHCCCEEEEECCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEC
EAPQKDTEKGVGCGCATMSRNDPPHLVALLDLLRQGKSMPYNEVKAGDVVNEFTGTRNRL
CCCCCHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCC
PVNDQQWVINNAKKALEMMINITEDRV
CCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFKNSTTYQPEATLMAIRNDMAICQSDYPLDWYQEDFIPYAQEYQALPDRKLTTVLNWMK
CCCCCCCCCCCCEEEEHHCCHHHHCCCCCCCHHHHHCCCHHHHHHCCCCHHHHHHHHHHH
PYLTKAQNHFGNKLLLLAHYYMGGEIVRLIEQFGGKIGDSYQLALMAANNPEKSVIVESA
HHHHHHHHHCCCEEEEEEHHHHCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHH
VHFMAESISILANENQHVYITNPKSGCTMEMLAKDFMVEPAFLDLNERYGAENILPVCYM
HHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCHHHCCCCCCCEEEEE
NTSGRVKAMTGAQGGAVCTSSNVKKIFQWAQKQNKKILFIPDQHMGENVAYWLGIKNLAY
CCCCCEEEEECCCCCEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCEEE
WPGGTAGANYSLPEQDKKTLKQFDKAELILFASQCAVHTHYQPEMCDYWKSQGYTTIVHP
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECHHHEECCCCCHHHHHHHHCCCEEEECC
ECRNDVIKVADYSGSTAFIWDLVVHDKAGTKSYAIGTENHMVENLKQYCKNLGIRVVNLA
HHCCCEEEEECCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEC
EAPQKDTEKGVGCGCATMSRNDPPHLVALLDLLRQGKSMPYNEVKAGDVVNEFTGTRNRL
CCCCCHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCC
PVNDQQWVINNAKKALEMMINITEDRV
CCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA