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The map label for this gene is sdhL [H]

Identifier: 54293772

GI number: 54293772

Start: 937851

End: 939227

Strand: Reverse

Name: sdhL [H]

Synonym: lpl0828

Alternate gene names: 54293772

Gene position: 939227-937851 (Counterclockwise)

Preceding gene: 54293776

Following gene: 54293767

Centisome position: 28.07

GC content: 41.18

Gene sequence:

>1377_bases
ATGAACATTAGTGTTTTTGATTTATTTTCTATAGGAATTGGGCCATCAAGCTCACACACAGTAGGCCCTATGTTAGCTGC
CAATGCTTTTTTGCAATTACTGGAGCAAAAAAATCTGTTTGATAAAACTCAGAGAGTCAAAGTAGAGCTTTATGGTTCGC
TGGCGCTTACTGGCAAGGGGCACGGTACTGATAAAGCCATTTTAAATGGTCTTGAAAACAAAGCGCCCGAGACAGTTGAT
CCTGCCTCCATGATCCCAAGAATGCATGAAATCCTTGATTCTAATCTACTCAATTTGGCCGGCAAGAAAGAAATTCCTTT
TCATGAGGCGACCGATTTTTTATTTTTACAAAAAGAATTATTACCCAAACACAGTAATGGAATGCGATTTTCTGCTTTTG
ATGGAAACGCTAATCTACTGATTGAACAAGTCTATTACTCTATTGGCGGCGGTTTTATTACAACTGAAGAAGACTTTGAT
AAATCAACAACCGATACCAATCCCCCCCCTTACCCCTTTGCAACAGCAACTGAATTATTGAATTTATGCAAAAAACATCA
CTTGACCATCGCTGAATTGATGTTAGTCAATGAAAAAACATGGAGAAGTACAGTAGAAATTCATAAAGGAATTCTGGACA
TTGCCAAAGTAATGGATGACTGTATCAATAACGGTTGCAAACACGATGGAGTGCTGCCTGGTGGCCTTAATTTAAAGCGA
CGGGCACCTGATTTGTATAGAAAATTAATAGAACAAAAAGGGGTTAAAAGTATTTTTGAACAATCAGATATTATGAATCA
TCTAAACCTTTATGCTATGGCTGTTAATGAAGAAAATGCAGCAGGAGGGCGAATTGTCACAGCCCCAACAAATGGAGCTG
CCGGGATTATTCCAGCTGTTCTTAAATATTGTCAGCAAGCTCACGACAGGATGAGCAACGAAGACATCTACACTTATTTT
CTGACTGCCGCAGCGATTGGAATCCTTTATAAAAAAGGCGCTTCAATTTCTGGCGCTGAAGTAGGATGCCAAGGTGAGGT
TGGTGTTGCCTCTTCCATGGCAGCTGCTGGTTTGACAGCGGTTCTTGGCGGAACCATCGAGCAGGTTGAAAATGCTGCAG
AAATTGCAATGGAACATCATCTGGGAATGACCTGTGATCCCGTTCTGGGCCTTGTGCAAATTCCATGCATCGAGAGAAAT
GCCATGGGAGCTGTGAAAGCAGTTAATGCAACCCGAATGGCACTCATAGGTGACGGTCAGCATCAAATCTCTTTGGATAA
AGTCATCAAAACAATGAAGCAAACCGGCATGGATATGCAAAGTATCTATAAGGAAACTTCCATGGGTGGATTAGCTGTTA
ACTTGCCTGAGTGTTAG

Upstream 100 bases:

>100_bases
AAAATTACCAGTCATAAGCTATCATTTAATTATATAATGGACAAAAAGGTAATATCCTTCTACACTTGCCCCTAATAATG
AACAAGAGATTTTAACGGCG

Downstream 100 bases:

>100_bases
TTATCTACCGCCCCTCACGGTCGCGGCTCGGATGATTAAATGAAATGATAATTAAAACTGAGCCACGACCGTGAGAGCGG
ATAACAAATTATCTAATTAA

Product: hypothetical protein

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNISVFDLFSIGIGPSSSHTVGPMLAANAFLQLLEQKNLFDKTQRVKVELYGSLALTGKGHGTDKAILNGLENKAPETVD
PASMIPRMHEILDSNLLNLAGKKEIPFHEATDFLFLQKELLPKHSNGMRFSAFDGNANLLIEQVYYSIGGGFITTEEDFD
KSTTDTNPPPYPFATATELLNLCKKHHLTIAELMLVNEKTWRSTVEIHKGILDIAKVMDDCINNGCKHDGVLPGGLNLKR
RAPDLYRKLIEQKGVKSIFEQSDIMNHLNLYAMAVNEENAAGGRIVTAPTNGAAGIIPAVLKYCQQAHDRMSNEDIYTYF
LTAAAIGILYKKGASISGAEVGCQGEVGVASSMAAAGLTAVLGGTIEQVENAAEIAMEHHLGMTCDPVLGLVQIPCIERN
AMGAVKAVNATRMALIGDGQHQISLDKVIKTMKQTGMDMQSIYKETSMGGLAVNLPEC

Sequences:

>Translated_458_residues
MNISVFDLFSIGIGPSSSHTVGPMLAANAFLQLLEQKNLFDKTQRVKVELYGSLALTGKGHGTDKAILNGLENKAPETVD
PASMIPRMHEILDSNLLNLAGKKEIPFHEATDFLFLQKELLPKHSNGMRFSAFDGNANLLIEQVYYSIGGGFITTEEDFD
KSTTDTNPPPYPFATATELLNLCKKHHLTIAELMLVNEKTWRSTVEIHKGILDIAKVMDDCINNGCKHDGVLPGGLNLKR
RAPDLYRKLIEQKGVKSIFEQSDIMNHLNLYAMAVNEENAAGGRIVTAPTNGAAGIIPAVLKYCQQAHDRMSNEDIYTYF
LTAAAIGILYKKGASISGAEVGCQGEVGVASSMAAAGLTAVLGGTIEQVENAAEIAMEHHLGMTCDPVLGLVQIPCIERN
AMGAVKAVNATRMALIGDGQHQISLDKVIKTMKQTGMDMQSIYKETSMGGLAVNLPEC
>Mature_458_residues
MNISVFDLFSIGIGPSSSHTVGPMLAANAFLQLLEQKNLFDKTQRVKVELYGSLALTGKGHGTDKAILNGLENKAPETVD
PASMIPRMHEILDSNLLNLAGKKEIPFHEATDFLFLQKELLPKHSNGMRFSAFDGNANLLIEQVYYSIGGGFITTEEDFD
KSTTDTNPPPYPFATATELLNLCKKHHLTIAELMLVNEKTWRSTVEIHKGILDIAKVMDDCINNGCKHDGVLPGGLNLKR
RAPDLYRKLIEQKGVKSIFEQSDIMNHLNLYAMAVNEENAAGGRIVTAPTNGAAGIIPAVLKYCQQAHDRMSNEDIYTYF
LTAAAIGILYKKGASISGAEVGCQGEVGVASSMAAAGLTAVLGGTIEQVENAAEIAMEHHLGMTCDPVLGLVQIPCIERN
AMGAVKAVNATRMALIGDGQHQISLDKVIKTMKQTGMDMQSIYKETSMGGLAVNLPEC

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=454, Percent_Identity=52.863436123348, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1788116, Length=455, Percent_Identity=50.989010989011, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1789161, Length=459, Percent_Identity=49.8910675381264, Blast_Score=420, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49505; Mature: 49505

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISVFDLFSIGIGPSSSHTVGPMLAANAFLQLLEQKNLFDKTQRVKVELYGSLALTGKG
CCCEEEEHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCC
HGTDKAILNGLENKAPETVDPASMIPRMHEILDSNLLNLAGKKEIPFHEATDFLFLQKEL
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LPKHSNGMRFSAFDGNANLLIEQVYYSIGGGFITTEEDFDKSTTDTNPPPYPFATATELL
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHH
NLCKKHHLTIAELMLVNEKTWRSTVEIHKGILDIAKVMDDCINNGCKHDGVLPGGLNLKR
HHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
RAPDLYRKLIEQKGVKSIFEQSDIMNHLNLYAMAVNEENAAGGRIVTAPTNGAAGIIPAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCHHHHHH
LKYCQQAHDRMSNEDIYTYFLTAAAIGILYKKGASISGAEVGCQGEVGVASSMAAAGLTA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VLGGTIEQVENAAEIAMEHHLGMTCDPVLGLVQIPCIERNAMGAVKAVNATRMALIGDGQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEECCC
HQISLDKVIKTMKQTGMDMQSIYKETSMGGLAVNLPEC
CCEEHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCC
>Mature Secondary Structure
MNISVFDLFSIGIGPSSSHTVGPMLAANAFLQLLEQKNLFDKTQRVKVELYGSLALTGKG
CCCEEEEHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCC
HGTDKAILNGLENKAPETVDPASMIPRMHEILDSNLLNLAGKKEIPFHEATDFLFLQKEL
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LPKHSNGMRFSAFDGNANLLIEQVYYSIGGGFITTEEDFDKSTTDTNPPPYPFATATELL
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHH
NLCKKHHLTIAELMLVNEKTWRSTVEIHKGILDIAKVMDDCINNGCKHDGVLPGGLNLKR
HHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
RAPDLYRKLIEQKGVKSIFEQSDIMNHLNLYAMAVNEENAAGGRIVTAPTNGAAGIIPAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCHHHHHH
LKYCQQAHDRMSNEDIYTYFLTAAAIGILYKKGASISGAEVGCQGEVGVASSMAAAGLTA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VLGGTIEQVENAAEIAMEHHLGMTCDPVLGLVQIPCIERNAMGAVKAVNATRMALIGDGQ
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEEECCC
HQISLDKVIKTMKQTGMDMQSIYKETSMGGLAVNLPEC
CCEEHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]